Oncorhynchus clarkii lewisi (westslope cutthroat trout): 139376925
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Entry
139376925 CDS
T10872
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ocla Oncorhynchus clarkii lewisi (westslope cutthroat trout)
Pathway
ocla00270
Cysteine and methionine metabolism
ocla00480
Glutathione metabolism
ocla01100
Metabolic pathways
ocla01240
Biosynthesis of cofactors
ocla04216
Ferroptosis
Module
ocla_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ocla00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
139376925
09106 Metabolism of other amino acids
00480 Glutathione metabolism
139376925
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
139376925
Enzymes [BR:
ocla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
139376925
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Motif
Pfam:
GCS
GCS2
HasA
Motif
Other DBs
NCBI-GeneID:
139376925
NCBI-ProteinID:
XP_070976033
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Position
20:76676782..76684931
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AA seq
630 aa
AA seq
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MGLLSKGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNGKVRLVLNGGEVLETLQDKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYKPTPVEKGVSKSLFFPDEAI
NQHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEKFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIMMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTGEERGLEPLKTNKFRILKSRYDSIDSYLSSCGDRYNDIDLTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFEEKIYLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAFVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDIYKGCNPALDSSSSAAQNGLDSEGDNEYTLMSIDTIINGKEGIFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHPQYKQDSVITDRI
NYDLLRKCDSITKGEERCPELIGDPVNRGK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcaaaagggtcaccgctcaactgggaagaaaccaaaaagtatgcagac
catgttcgaaaacatggcatcgttcagtttctcaacatctataacaaggtgaaagaacga
cagaaagatgtgttattatggggcgatgaggtggaatacatgttgatcgaaatggatgag
aaaaatggaaaggttcgtcttgttctcaatggtggggaggttttggaaacccttcaagac
aaaggagaaaagaccaaccccaaccatcctaccctttggaggccagagtatggcagctac
atgatcgaagggactccggggcagccctatggtgggacgatgtcagagttcaacacagtg
gaggacaacatggggaagcgaaggcgagaggcctcatctgtgctgaataagaatgaaacg
cttgccaccatcacgtcattcccaaggttaggctgcccaggcttcacacagccagaatac
aagccaacacctgttgaaaagggagtgtcaaaatcactgttcttcccagatgaagccata
aaccaacacccaagattcagcaccctgaccagaaacattcgtcacagaagaggagagaag
gtggtgatcaacgtacccatctttaaagacaaatgcaccccatctccatttgtggagaag
tttccggaagacgatggggaggctgccagggcagctctacctgatcacatctacatggat
gccatgggatttggaatgggcaactgctgtcttcaggtgacattccaagcttgcagcatt
gaagaggcgaggtacctttatgaccaactagcaacattctgccctataatgatggctctc
agtgctgcttcgccgttctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcctcggtagatgacaggaccggggaagagagggggctggagcctttgaaaacc
aacaaatttcgaatcttgaaatccagatatgattcaatcgacagctacctctccagctgt
ggcgataggtacaatgacatagatctgacaatagacgaggagatcaacaaacagctgctg
gatgcagggatcgacaaactgctggcccaacacatagcccatctcttcattcgggatccg
ctctcactatttgaagagaaaatttacttggatgatgaaaacgagtctgatcactttgag
aatctgcagtcaaccaactggcagacaatgaggttcaaacctcctcctccaaactcggac
atcggatggcgagttgagttccgtcccatggaggtgcaacttaccgattttgaaaactct
gcattcgttgttttcatcgtcctgctcaccagggttatactgtcctataaactggacttt
ctcatccccttgtcaaaggttgatgaaaacatgaaagttgcccagaaaagaaatgcagtc
caagagggcatgttttacttccggaaggacatctataaaggctgcaaccctgccctcgat
agctcctcatcggctgcccagaatggcttggacagtgagggtgacaatgagtacacactg
atgagcattgacacaatcatcaatggaaaggaaggaatttttcaagggttgataccaatc
ctcaactgctacctagaaaacatggaggtggatgttgatacaagatgcaccatcctgaac
tacctgaagctcatcaagagacgtgcctccggtgaactgatgaccatggctaaatggatg
agggagtttgtggacaagcacccccaatacaagcaagacagtgtcataactgacagaatc
aactacgacctactccgcaagtgtgacagcatcacaaaaggagaggagcgatgcccagaa
cttattggtgacccagtcaatcggggcaaatga
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