Oryctolagus cuniculus (rabbit): 100008676 Help Entry 100008676         CDS       T03373                                  Symbol PKM Name (RefSeq) pyruvate kinase PKM isoform 1   KO K00873   pyruvate kinase [EC:2.7.1.40] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00010   Glycolysis / Gluconeogenesis ocu00620   Pyruvate metabolism ocu01100   Metabolic pathways ocu01200   Carbon metabolism ocu01230   Biosynthesis of amino acids ocu04922   Glucagon signaling pathway ocu04930   Type II diabetes mellitus ocu05165   Human papillomavirus infection ocu05203   Viral carcinogenesis ocu05230   Central carbon metabolism in cancer Module ocu_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ocu_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100008676 (PKM)    00620 Pyruvate metabolism     100008676 (PKM)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     100008676 (PKM)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     100008676 (PKM)    05230 Central carbon metabolism in cancer     100008676 (PKM)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100008676 (PKM)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100008676 (PKM)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ocu04131]     100008676 (PKM)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ocu04147]     100008676 (PKM) Enzymes [BR:ocu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      100008676 (PKM) Membrane trafficking [BR:ocu04131]  Autophagy   Chaperone mediated autophagy (CMA)    Selective cargos     100008676 (PKM) Exosome [BR:ocu04147]  Exosomal proteins   Proteins found in most exosomes    100008676 (PKM) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C HpcH_HpaI Motif Other DBs NCBI-GeneID:  100008676 NCBI-ProteinID:  NP_001182573 Ensembl:  ENSOCUG00000006119 UniProt:  P11974 Structure PDBPDBj LinkDB All DBs Position 17:1302766..1326053 Genome browser AA seq 531 aa AA seqDB search MSKSHSEAGSAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVET LKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGL ISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV FASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE IPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSHSTDLMEAMAMGSVEAS YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQE AWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt atgtcgaagtcccacagtgaagccgggtctgccttcatccagacgcagcagctgcacgca gccatggcggacacattcctggagcacatgtgccggctggacatcgactccgcgcccatc acggcccgcaacacgggcatcatctgtaccatcggccctgcctcccgatcggtggagacg ctgaaggagatgatcaagtctgggatgaacgtggcgcgcatgaacttctcccacggaact cacgagtaccatgcggagaccatcaagaacgtgcgcacagccacggaaagctttgcctca gaccccatcctctaccggcccgtcgcggtggctctggacactaagggacccgagatccga acggggctcatcaagggcagcggcacggcggaggtggagctgaagaagggagccacgctc aagatcacgctggacaacgcctacatggagaagtgcgacgagaacatcctgtggctggac tacaagaacatttgcaaggtggtggacgtgggcagcaaggtctacgtggacgacggcctc atctccctgcaggtgaagcagaaaggtcctgacttcctggtgacggaggtggagaacggt ggcttcttgggcagcaagaagggcgtgaacctccccggggctgcggtggacctgcctgcc gtgtccgagaaggacatccaggatctgaagttcggcgtggagcaggacgtggacatggtg tttgcctctttcatccgcaaggcggctgacgtccatgaggtcaggaagatcctgggagag aaagggaagaacatcaagatcatcagcaaaattgagaaccacgagggggtgcgcaggttt gatgagatcctggaggccagcgacgggatcatggtggctcgtggtgatcttggcattgag attcctgcagagaaggtcttccttgcccagaagatgataattgggcgatgcaaccgtgct gggaagcctgtcatctgtgccacgcagatgctggagagcatgatcaagaagccccgcccc acccgcgccgagggcagtgacgtggccaacgcggtcctggatggagccgactgcatcatg ctgtctggagagacggccaagggcgactacccgctggaggccgtccgcatgcagcacctg atagctcgcgaggctgaggcagccatgttccaccgcaagctgttcgaagaacttgcgcga gcctccagtcactccacagacctcatggaggccatggccatgggcagcgtggaggcttcc tataagtgtttagcggcagctttgatagttctgacggagtctggcaggtctgctcaccaa gtggcccggtaccgcccgcgcgcccccatcattgccgtgacacggaaccaccagaccgcc cgccaggcccacctgtaccgtgggatcttcccggtggtgtgtaaggatccggtccaggag gcctgggctgaggatgtcgacctccgggtgaacttggccatgaatgtcggcaaggcccgc ggtttcttcaagaagggagatgtggtcattgtgctcaccggatggcgccctggctctggc ttcaccaacaccatgcgcgtggtgcccgtgccgtga

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