Oryctolagus cuniculus (rabbit): 100008746
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Entry
100008746 CDS
T03373
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
KO
K12385
Niemann-Pick C1 protein
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
ocu04142
Lysosome
ocu04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
100008746 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
100008746 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
100008746 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
ocu02000
]
100008746 (NPC1)
Transporters [BR:
ocu02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
100008746 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
100008746
NCBI-ProteinID:
NP_001075540
Ensembl:
ENSOCUG00000009850
UniProt:
Q9TT75
LinkDB
All DBs
Position
9:51377392..51426957
Genome browser
AA seq
1286 aa
AA seq
DB search
MSAAPRGGPVSARGRLLGLLLLLLCPAQVLPQSCVWYGECGIASGDKRYNCQYSGPPKPL
PKDGYDLIQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCEL
TCSPRQSQFLNVTATEAYVDPATNQTKTNVKELQYYIGQRFADAMYNACRDVEAPSSNDK
ALGLLCGKDANACNATNWIEYMFDKNNGQAPFTITPIFSDLPVRGMEPMNNATKGCNEAV
DEVTGPCSCQDCSVVCGPKPQPPPPPIPWRIFGLDAMYVIMWITYMAFLFMFFGTFFAVW
CYRKRYFVSEYTPIDSNIAFSVNTSDKGEASCCDLLGAAFEGCLRRLFTRWGSFCVRNPG
CVIFFSLGFIAACSSGLVYVRVTTNPIDLWSAPSSQARQDKEFFDAHFGPFFRTEQLIIR
APHTNKHTYQPYPSGADVPFGPPLDKQILHQVLDLQTAIEDITASYNNETVTLQDICLAP
LSPYNKNCTILSVLNYFQNSHSMLDHEQGDDFFVYADYHTHFLYCVRVPASLNDTSLLHD
PCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVSNYYNDTEKLQRAKAWEKEFINFV
KNYENPNLTISFTAERSIEDELDRESNSDVFTVVISYAVMFLYISLALGHIKSCRRFLVD
SKVSLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQR
DERLQGETLDQQLGRVLGEVAPSIFLSSFAETVAFFLGGLSVMPAVHTFSLFAGMAVFID
FLLQITCFVSLLGLDIKRQEKNQLDVLCCFRGAEAGTSIQASESYLFRFFKNSYSPLLLK
DWMRPIVIAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVVDYFKSLGQYLHAGPPVYF
VLEEGHNYTSLQGQNMVCGGLGCDNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVK
PQSSCCRVSNVTEQFCNASVVDPACVRCRPLTPEGKQRPQGEDFMRFLPMFLSDNPNPKC
GKGGHAAYGTAVNILGNGTEVGATYFMTYHTVLQTSADFIDAMKKAQLIAGNATATMGLK
GSRCRVFPYSVFYVFYEQYLTILDDAVFNLGVSLGAVFVVAVVLLGCELWSAVIMCVTIT
MILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSGKGSRVARAEEALA
HMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIG
PSTNKAKSCATQERYKGTERERLLNF
NT seq
3861 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcagccccacgcggcggccccgtgagcgcgcgcggccggttgctcggcctgctc
ctgctgctgctgtgcccggcgcaggtgcttccccagtcctgtgtttggtatggagagtgt
ggcattgcctccggagataagagatacaactgccaatattctggcccgccaaaaccattg
cccaaggatggctacgacttaatacaggaactctgtccaggatttttctttgacaatgtc
agcctctgttgtgatgtgcagcagcttcaaacactgaaagacaacctgcagctgccgcta
cagtttctgtccagatgtccgtcctgtttctataacctaatgaacctgttttgtgagctg
acatgcagccctcgccagagtcagtttctgaatgttacagccactgaagcgtatgtagat
cctgccacgaaccagacaaaaacaaacgtaaaggaattacagtactacattggacagagg
ttcgccgatgccatgtacaacgcctgccgggacgtagaggccccctccagtaatgacaag
gccctgggcctgctgtgtgggaaggacgccaacgcctgcaatgctaccaactggatcgag
tacatgttcgacaagaacaacggacaggcaccctttaccatcacccccatcttctcagat
ctcccagtccgtgggatggagcccatgaataatgccaccaaaggctgcaacgaggctgta
gatgaggtcacggggccctgcagctgccaggactgctccgtcgtttgtggtcctaagccc
cagcccccgccacctcccataccctggagaatctttggcttggacgccatgtatgtcatc
atgtggatcacctacatggcatttctgtttatgttttttggaacgttttttgcagtgtgg
tgctacagaaagcggtactttgtttctgagtacactcccattgatagcaacatagctttc
tctgttaacaccagcgacaaaggggaggcgtcctgctgcgacctgctaggggcagcattt
gagggctgtctgaggagactcttcactcgctggggatccttctgtgtccgaaaccccggc
tgcgtcatcttcttctcactcggcttcatcgccgcgtgttcttcaggcctggtgtatgtc
cgggtcaccaccaaccccattgacctgtggtcagcgcccagcagccaggcccgccaggac
aaagagttctttgacgcgcactttgggcctttcttccggaccgagcagctcatcatccga
gccccccacaccaacaagcacacctaccagccgtacccctcgggcgccgacgtgcccttt
ggaccaccgctcgacaaacagattttgcaccaggttcttgacttgcagacagccattgaa
gacattactgcatcctacaacaacgagactgtgacacttcaggacatctgcttggcccct
ctctcaccatataacaagaactgcaccatcctgagcgtgttaaactacttccagaacagc
cattccatgctggaccacgagcaaggggacgacttctttgtgtacgccgattaccacacg
cactttctctactgtgtccgggttcctgcctctctgaatgatacaagtttgctccatgat
ccttgtctgggcacatttggtggcccagtgttcccgtggcttgtgttaggaggctatgat
gatcaaaactacaacaatgccaccgccctcgtgattaccttccctgtcagtaattactat
aatgatacagagaagctccagagggccaaggcctgggaaaaagagtttattaattttgtg
aaaaactacgagaatccaaacctgaccatctctttcactgccgagcgcagtattgaagat
gaactagatcgcgaaagtaacagcgacgtcttcaccgtcgtcattagctatgccgtcatg
tttctgtatatttccctggccttggggcacatcaaaagctgccgcaggtttctggtggat
tcgaaagtctccctgggcatcgcgggcatcctgattgtgctgagctcggtggcctgctcc
ttgggcatcttcagctacattgggatccccttgaccctcatcgtgatcgaagtcatccca
ttcctggtgctggctgtcggggtggacaacatcttcattctggtgcagacttaccagaga
gatgaacgtcttcaaggggaaaccctggaccagcagctgggccgggtcctgggagaagta
gctcctagcatcttcctgtcctcctttgccgagacggtagcatttttcttaggaggcctg
tcggtgatgccggccgtccacaccttctccctgtttgcggggatggcggtcttcattgac
ttcctcctccagatcacctgctttgtgagtcttttgggattagacattaagcgtcaagag
aaaaaccagctggacgtcctgtgctgcttcaggggtgcagaggctgggacgagcattcag
gcctccgagagctacttgtttcgcttcttcaaaaactcctattctccacttctgctcaag
gactggatgcggcccattgtgatagcggtatttgtgggcgttctctcgttcagcatcgca
gtcctgaacaaggtggaaattggattggatcagtctctctcaatgcctgacgactcctac
gtggtggattatttcaagtccctcgggcagtacctgcatgcggggccgcccgtgtacttt
gtcctggaggaagggcacaactacacctccctgcaggggcagaacatggtgtgcggcggc
ctgggctgcgacaacgactccttggtgcagcagatattcaacgcggcccagctggacaac
tacacccgcatcggcttcgcgccctcctcctggatcgacgattacttcgattgggtgaag
ccgcagtcgtcttgctgccgggtctccaacgtcacggagcagttctgcaacgcctcagtg
gtggaccctgcctgcgtccgctgcaggccgctcaccccagagggcaagcagaggcctcag
ggggaggacttcatgagattcctgcccatgttcctgtctgacaaccccaaccccaagtgt
ggcaaagggggacatgctgcttacggcaccgcagtcaacatcctgggcaacggcaccgag
gtcggggccacgtacttcatgacctaccacaccgtgctgcagacctcggccgacttcatc
gacgccatgaagaaagcccagctgatagccgggaacgccaccgccaccatgggcctgaag
ggcagccgttgccgggtgttcccgtacagtgtgttctacgtcttctatgaacagtacctc
accattctggacgatgccgtctttaacctcggcgtgtccctgggagcggtgttcgtggtg
gccgtggtgctcctgggctgtgagctctggtctgcagtcatcatgtgtgtcaccatcacc
atgatcttggtcaacatgtttggggtcatgtggctgtggggcatcagcctgaacgcggtg
tccttggtcaacctggtgatgagctgtggcatctccgtggagttctgcagccacataacc
agagcgttcacagtgagtggcaaaggaagccgagtggcccgcgcggaggaggcgctcgct
cacatgggcagctctgtattcagtggaatcacacttacaaaatttggagggattgtggtg
ttggcttttgccaaatctcagattttccagatcttttacttcaggatgtatttggccatg
gtcctgctgggcgccacgcacgggttgatattcctcccggtcttgctcagttacataggc
ccttcaacaaataaagccaaaagttgtgccactcaagagcgatacaaaggtactgagcga
gagcgactcctaaatttctag
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