Oryctolagus cuniculus (rabbit): 100008806 Help Entry 100008806         CDS       T03373                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu01521   EGFR tyrosine kinase inhibitor resistance ocu01522   Endocrine resistance ocu04010   MAPK signaling pathway ocu04012   ErbB signaling pathway ocu04014   Ras signaling pathway ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04066   HIF-1 signaling pathway ocu04068   FoxO signaling pathway ocu04072   Phospholipase D signaling pathway ocu04144   Endocytosis ocu04151   PI3K-Akt signaling pathway ocu04510   Focal adhesion ocu04520   Adherens junction ocu04540   Gap junction ocu04630   JAK-STAT signaling pathway ocu04810   Regulation of actin cytoskeleton ocu04912   GnRH signaling pathway ocu04915   Estrogen signaling pathway ocu04921   Oxytocin signaling pathway ocu04926   Relaxin signaling pathway ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu05160   Hepatitis C ocu05163   Human cytomegalovirus infection ocu05165   Human papillomavirus infection ocu05171   Coronavirus disease - COVID-19 ocu05200   Pathways in cancer ocu05205   Proteoglycans in cancer ocu05206   MicroRNAs in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05208   Chemical carcinogenesis - reactive oxygen species ocu05210   Colorectal cancer ocu05212   Pancreatic cancer ocu05213   Endometrial cancer ocu05214   Glioma ocu05215   Prostate cancer ocu05218   Melanoma ocu05219   Bladder cancer ocu05223   Non-small cell lung cancer ocu05224   Breast cancer ocu05225   Hepatocellular carcinoma ocu05226   Gastric cancer ocu05230   Central carbon metabolism in cancer ocu05231   Choline metabolism in cancer ocu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100008806 (EGFR)    04012 ErbB signaling pathway     100008806 (EGFR)    04014 Ras signaling pathway     100008806 (EGFR)    04015 Rap1 signaling pathway     100008806 (EGFR)    04630 JAK-STAT signaling pathway     100008806 (EGFR)    04066 HIF-1 signaling pathway     100008806 (EGFR)    04068 FoxO signaling pathway     100008806 (EGFR)    04020 Calcium signaling pathway     100008806 (EGFR)    04072 Phospholipase D signaling pathway     100008806 (EGFR)    04151 PI3K-Akt signaling pathway     100008806 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100008806 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100008806 (EGFR)    04520 Adherens junction     100008806 (EGFR)    04540 Gap junction     100008806 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100008806 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     100008806 (EGFR)    04915 Estrogen signaling pathway     100008806 (EGFR)    04921 Oxytocin signaling pathway     100008806 (EGFR)    04926 Relaxin signaling pathway     100008806 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     100008806 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100008806 (EGFR)    05206 MicroRNAs in cancer     100008806 (EGFR)    05205 Proteoglycans in cancer     100008806 (EGFR)    05207 Chemical carcinogenesis - receptor activation     100008806 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     100008806 (EGFR)    05230 Central carbon metabolism in cancer     100008806 (EGFR)    05231 Choline metabolism in cancer     100008806 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100008806 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     100008806 (EGFR)    05212 Pancreatic cancer     100008806 (EGFR)    05225 Hepatocellular carcinoma     100008806 (EGFR)    05226 Gastric cancer     100008806 (EGFR)    05214 Glioma     100008806 (EGFR)    05218 Melanoma     100008806 (EGFR)    05219 Bladder cancer     100008806 (EGFR)    05215 Prostate cancer     100008806 (EGFR)    05213 Endometrial cancer     100008806 (EGFR)    05224 Breast cancer     100008806 (EGFR)    05223 Non-small cell lung cancer     100008806 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     100008806 (EGFR)    05171 Coronavirus disease - COVID-19     100008806 (EGFR)    05163 Human cytomegalovirus infection     100008806 (EGFR)    05165 Human papillomavirus infection     100008806 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100008806 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100008806 (EGFR)    01522 Endocrine resistance     100008806 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ocu01001]     100008806 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ocu04147]     100008806 (EGFR) Enzymes [BR:ocu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100008806 (EGFR) Protein kinases [BR:ocu01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    100008806 (EGFR) Exosome [BR:ocu04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    100008806 (EGFR)   Exosomal proteins of pancreatic cancer cells    100008806 (EGFR)   Exosomal proteins of bladder cancer cells    100008806 (EGFR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like Kinase-like APH ABC1 Kdo Motif Other DBs NCBI-GeneID:  100008806 NCBI-ProteinID:  XP_008260065 Ensembl:  ENSOCUG00000010481 LinkDB All DBs Position 10:complement(45658882..45803851) Genome browser AA seq 1209 aa AA seqDB search MRPSGPVGPALLALLAALLQAGQALEEKRVCQGTSNKLTQLGPFEDHFLSLQRMFNSCEV VLGNLEITYVQRNHDLSFLKTIQEVAGYVLIALNTVESIPLESLQIIRGNVLYENTYALA VLSNYGANKTGLRELPMRNLQEILHGAVRFSNNPVLCNVETIQWRDIVHGDFLSNMSLDM QNPLGSCQKCDPSCPNGSCWGAGGENCQRLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV VTDHGSCVRACGPDSYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK NCTSISGDLHILPVAFRGDSFTRTPPLDPEELDILKTVREITGFLLIQAWPENKTDLHAF ENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLQEISDGDVIVSGNRDLCYANTINWKKL FGTSSQKTKIINNRGDKDCKAAGHVCDPLCSSEGCWGPEPRDCVSCRNVSRGKECVERCN VLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIKCAHFIDGPHCVKTCPAGVM GENDTLVWKFADAGRICRLCHPNCTYGCAGPGLEGCATNGPKIPSIATGVVGGLFLLVVL GLGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKLKVLGS GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI CLTSTVQLVTQLMPFGCLLDYVREHKDNIGSQHLLNWCVQIAKGMNYLEDRRLVHRDLAA RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY GVTVWELMTFGSKPYDGIPASEIASVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK FRELIVEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMGDVIDADEYLIPQ QGFFNSPSTSRTPLLSSLSATSNSSTMACVDRNGQSCPVKEDSLLQRYSSDPTGGVTEDS MDDTFLPVPEYINQYIPKRPAGSVQNPVYHNQPLHPAPGRDPHYQDPHSSAVGNPEYLNT TQPPCPNGIFDSPTPWAQKGSHQMSLDNPDYQQDFFPKDGKLNGIFKGPTAENAEYLRVA PPGREFTTA NT seq 3630 nt NT seq  +upstreamnt  +downstreamnt atgcgaccctcggggccggtcgggcccgcgctcctggcgctgctggccgcgctcctgcag gcgggacaggcgctggaggagaagagagtttgccagggcacaagcaacaagctgacccag ctgggcccttttgaggaccacttcctgagcctgcagaggatgttcaacagctgtgaggtg gtgctggggaacctggagatcacctacgtgcagaggaaccacgacctctccttcttaaag accatccaggaggtggctggctacgtgctcattgccctcaacaccgtggagagcatccct ttggagagcctgcaaatcatccgaggaaacgtgctgtatgagaacacctacgccttagcc gttctgtccaactacggagccaacaagaccgggctgagggagctgcccatgcggaacttg caggaaatccttcatggagctgtgcgattcagcaacaaccctgtcctgtgcaatgtggag accatccagtggcgggacattgttcacggtgactttctgagcaacatgtctctggacatg cagaaccccctgggcagctgccagaagtgtgacccaagctgtcccaatggaagctgctgg ggcgcaggcggcgagaactgccagagactgaccaaaatcatctgcgcccagcagtgctct ggacgctgccgcggcaagtcccccagcgactgctgccacaaccagtgtgctgctggctgc acaggcccacgggagagcgactgcttggtctgccgtaaattcagagacgaagccacatgc aaggacacctgcccacctctcatgctgtacaaccccaccacatatcagatggatgtcaac cccgagggaaaatacagctttggtgccacctgtgtcaagaaatgtccccgtaactacgtg gtgacagatcatggctcctgtgtccgggcctgtggtcctgacagctacgaggtggaggaa gatggcgtccgcaagtgtaagaagtgcgaggggccttgtcgcaaagtttgtaatgggata ggaattggtgaatttaaagacacgttgtccataaatgccacaaacatcaaacacttcaaa aactgcacgtccatcagtggtgatctgcacatcctgccggtggcattcaggggggattcc ttcacccgcaccccgcccctggaccccgaggagctggacatcctgaaaaccgtgcgggag atcacagggtttctactgattcaggcgtggccagaaaacaagactgacctccatgccttt gagaacctagaaatcatccgtggcaggacaaagcagcatggtcagttttctcttgcggtt gtcggcctggacataacatccctgggactgcgctccctccaagagattagcgatggagac gtgatcgtttcaggaaaccgagacctgtgctatgcaaacacaataaactggaaaaagctt tttggaacctccagccagaaaaccaaaattatcaacaaccggggagacaaggactgcaag gccgctggccacgtctgtgacccgctgtgctcatcggagggctgctggggccccgagccc agggactgtgtctcctgccggaatgtcagccgtggcaaggagtgtgtggagaggtgcaac gttctggagggtgagcccagggagtttgtggagaactctgagtgcattcagtgccatccg gaatgtctgccccaggccatgaacatcacctgcacaggacggggtccagataactgcatc aagtgtgcacacttcatcgatggccctcactgcgtcaagacctgcccagcaggagtcatg ggggaaaacgacaccctggtctggaagtttgccgacgctggacgcatctgccgcctgtgc cacccaaactgcacctatggctgtgctgggccaggtctcgaaggctgtgcaacaaatggg cccaaaatcccctccatcgccacgggggtcgtgggcggcctcttcctgctggtggtgctg ggcctcggcatcggcctcttcatgcgcaggcgccacattgtccggaagcgcacattgcgc cgactgctgcaggagagagagctcgtggagcctcttacacccagtggggaggcccccaac caagccctcctgaggattttaaaggaaacagaattcaagaagctcaaagtcctgggctct ggagcgtttggcaccgtgtataagggactctggattccagaaggcgagaaagttaaaatc cctgtggccatcaaggagttaagagaagccacgtctccaaaggccaacaaggagatcctg gatgaggcctacgtgatggccagcgtggacaacccccatgtgtgtcgcctcctgggcatc tgcctgacctccactgtgcagctcgtcacacagctcatgcccttcggttgcctgctggac tacgtccgagagcacaaagacaacatcggctcccagcacctgctcaactggtgtgtgcag attgcaaagggcatgaactacctggaggaccggcgtctggtgcaccgcgacctggctgcc aggaatgtgctggtaaagacaccgcaacacgtcaagatcacagattttgggctggccaag ctgctcggtgcagaggagaaagaataccatgcagaggggggcaaggtccccatcaagtgg atggctttggaatcgattttacaccggatttacacccaccagagtgatgtctggagctac ggagtcaccgtttgggagttgatgacctttgggtccaagccttacgacggaatccctgcc agtgagatcgcgtctgtgctggagaaaggagaacgacttccacagccccccatctgcact attgacgtctacatgatcatggtcaagtgctggatgatagatgctgacagtcgcccaaag ttccgggagttgattgtggaattttccaaaatggcccgagaccctcagcgttaccttgtc attcagggggatgagcggatgcatttgccaagccctacagattccaatttttaccgtgcc ctgatggacgaagaagacatgggcgacgtcatagatgctgacgagtacctcattcctcag cagggcttcttcaacagcccctccacatcacggacgccgctcttaagctctctgagtgcg accagcaacagttccaccatggcttgtgtggataggaacgggcagagctgtcctgtcaag gaagacagcctcctgcagcggtacagctcagaccccactggtggcgtgactgaggacagc atggatgacacgtttctcccagtgcctgaatacataaaccagtacattcccaagaggcct gcaggctctgtgcagaaccctgtctaccataaccagcctctgcacccggctccgggcaga gacccccactaccaggatccccacagcagcgcagtgggaaaccctgaatatctcaacacc acccagcctccctgtcccaatggcatctttgacagccccaccccctgggcccagaagggc agccaccaaatgagcctggacaaccccgattaccagcaagacttttttcccaaggatggc aagctgaatggcatcttcaagggtcctacggctgaaaacgcagaatacctaagggtagca ccaccaggccgtgaatttaccacagcgtga

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