KEGG   Oryctolagus cuniculus (rabbit): 100008856
Entry
100008856         CDS       T03373                                 
Symbol
JUN
Name
(RefSeq) transcription factor Jun
  KO
K04448  transcription factor AP-1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04024  cAMP signaling pathway
ocu04137  Mitophagy - animal
ocu04210  Apoptosis
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04510  Focal adhesion
ocu04530  Tight junction
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04662  B cell receptor signaling pathway
ocu04668  TNF signaling pathway
ocu04722  Neurotrophin signaling pathway
ocu04912  GnRH signaling pathway
ocu04915  Estrogen signaling pathway
ocu04921  Oxytocin signaling pathway
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05030  Cocaine addiction
ocu05031  Amphetamine addiction
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05161  Hepatitis B
ocu05162  Measles
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05200  Pathways in cancer
ocu05203  Viral carcinogenesis
ocu05207  Chemical carcinogenesis - receptor activation
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05224  Breast cancer
ocu05231  Choline metabolism in cancer
ocu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100008856 (JUN)
   04012 ErbB signaling pathway
    100008856 (JUN)
   04310 Wnt signaling pathway
    100008856 (JUN)
   04668 TNF signaling pathway
    100008856 (JUN)
   04024 cAMP signaling pathway
    100008856 (JUN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100008856 (JUN)
  09143 Cell growth and death
   04210 Apoptosis
    100008856 (JUN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100008856 (JUN)
   04530 Tight junction
    100008856 (JUN)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100008856 (JUN)
   04621 NOD-like receptor signaling pathway
    100008856 (JUN)
   04625 C-type lectin receptor signaling pathway
    100008856 (JUN)
   04660 T cell receptor signaling pathway
    100008856 (JUN)
   04658 Th1 and Th2 cell differentiation
    100008856 (JUN)
   04659 Th17 cell differentiation
    100008856 (JUN)
   04657 IL-17 signaling pathway
    100008856 (JUN)
   04662 B cell receptor signaling pathway
    100008856 (JUN)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100008856 (JUN)
   04915 Estrogen signaling pathway
    100008856 (JUN)
   04921 Oxytocin signaling pathway
    100008856 (JUN)
   04926 Relaxin signaling pathway
    100008856 (JUN)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100008856 (JUN)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100008856 (JUN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100008856 (JUN)
   05207 Chemical carcinogenesis - receptor activation
    100008856 (JUN)
   05208 Chemical carcinogenesis - reactive oxygen species
    100008856 (JUN)
   05203 Viral carcinogenesis
    100008856 (JUN)
   05231 Choline metabolism in cancer
    100008856 (JUN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100008856 (JUN)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100008856 (JUN)
   05211 Renal cell carcinoma
    100008856 (JUN)
   05224 Breast cancer
    100008856 (JUN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100008856 (JUN)
   05170 Human immunodeficiency virus 1 infection
    100008856 (JUN)
   05161 Hepatitis B
    100008856 (JUN)
   05171 Coronavirus disease - COVID-19
    100008856 (JUN)
   05162 Measles
    100008856 (JUN)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100008856 (JUN)
   05169 Epstein-Barr virus infection
    100008856 (JUN)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100008856 (JUN)
   05135 Yersinia infection
    100008856 (JUN)
   05133 Pertussis
    100008856 (JUN)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100008856 (JUN)
   05142 Chagas disease
    100008856 (JUN)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100008856 (JUN)
   05321 Inflammatory bowel disease
    100008856 (JUN)
  09165 Substance dependence
   05030 Cocaine addiction
    100008856 (JUN)
   05031 Amphetamine addiction
    100008856 (JUN)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100008856 (JUN)
   05418 Fluid shear stress and atherosclerosis
    100008856 (JUN)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100008856 (JUN)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100008856 (JUN)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100008856 (JUN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ocu03000]
    100008856 (JUN)
Transcription factors [BR:ocu03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    100008856 (JUN)
SSDB
Motif
Pfam: Jun bZIP_1 bZIP_2 bZIP_Maf ZapB PspA_IM30 Fib_alpha DUF3450 FlaC_arch
Other DBs
NCBI-GeneID: 100008856
NCBI-ProteinID: NP_001185876
LinkDB
Position
13:108115505..108116620
AA seq 337 aa
MSAKMETTFYDDALNASFLQTESGAYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
LHSQNTLPSVTSAAQPVSGAGMVAPAVASVAGGGGGSGGFSAGLHSEPPVYANLSNFNPS
ALSSGGGAPSYGAAGLAFPAQPQQQQPPPPPQPPHHLPQQIPVQHPRLQALKEEPQTVPE
MPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSEL
ASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
NT seq 1014 nt   +upstreamnt  +downstreamnt
atgagtgcaaagatggaaacgaccttctacgacgatgccctcaacgcctcgttcctgcag
accgagagcggcgcctacggctacagtaaccccaagatcctgaaacagagcatgaccctg
aacctggccgacccggtgggcagcctgaagccgcacctccgcgccaagaactcggacctc
ctcacctctcccgacgtggggctgctcaagctggcgtcgcccgagctggagcgcctcatc
atccagtccagcaacgggcacatcaccaccacgccgacccccacccagttcctgtgcccc
aagaacgtgaccgacgagcaggagggcttcgccgagggcttcgtgcgcgccctagccgag
ctgcacagccagaacacgctgcccagcgtcacgtccgcggcgcagccggtcagcggggcg
ggcatggtggctccggccgtggcctcggtggcgggcggcggcggcggcagcggcggcttc
agcgccggcctgcacagcgagccgcctgtctacgccaacctcagcaacttcaacccgagc
gcgctgagcagcggcggcggggcgccctcctacggcgcggccggcctggcctttcccgcg
cagccccagcagcaacagccgccgccgccgccgcagccgccgcaccacctgccccagcag
atccccgtgcagcacccgcggctgcaggcgctcaaggaggagccgcagaccgtgcccgag
atgcccggcgagacgccgcccctgtcccccattgacatggagtcccaggagcggatcaag
gcggagaggaagcgcatgaggaaccgcatcgccgcctccaagtgccggaaaaggaagctg
gagaggatcgctcggctggaggaaaaagtgaaaaccttgaaagcgcagaactcggagctg
gcgtccacggccaacatgctcagggaacaggtggcacagctgaaacagaaagtcatgaac
cacgttaacagcgggtgccaactcatgctaacgcagcagttgcaaacgttctga

KEGG   Oryctolagus cuniculus (rabbit): 100337999
Entry
100337999         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04014  Ras signaling pathway
ocu04024  cAMP signaling pathway
ocu04068  FoxO signaling pathway
ocu04071  Sphingolipid signaling pathway
ocu04137  Mitophagy - animal
ocu04140  Autophagy - animal
ocu04141  Protein processing in endoplasmic reticulum
ocu04210  Apoptosis
ocu04215  Apoptosis - multiple species
ocu04217  Necroptosis
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04510  Focal adhesion
ocu04530  Tight junction
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04722  Neurotrophin signaling pathway
ocu04723  Retrograde endocannabinoid signaling
ocu04728  Dopaminergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04910  Insulin signaling pathway
ocu04912  GnRH signaling pathway
ocu04914  Progesterone-mediated oocyte maturation
ocu04917  Prolactin signaling pathway
ocu04920  Adipocytokine signaling pathway
ocu04926  Relaxin signaling pathway
ocu04930  Type II diabetes mellitus
ocu04931  Insulin resistance
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05010  Alzheimer disease
ocu05012  Parkinson disease
ocu05016  Huntington disease
ocu05017  Spinocerebellar ataxia
ocu05020  Prion disease
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05142  Chagas disease
ocu05145  Toxoplasmosis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05162  Measles
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05200  Pathways in cancer
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05231  Choline metabolism in cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100337999
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100337999
   04012 ErbB signaling pathway
    100337999
   04014 Ras signaling pathway
    100337999
   04310 Wnt signaling pathway
    100337999
   04668 TNF signaling pathway
    100337999
   04068 FoxO signaling pathway
    100337999
   04071 Sphingolipid signaling pathway
    100337999
   04024 cAMP signaling pathway
    100337999
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100337999
   04137 Mitophagy - animal
    100337999
  09143 Cell growth and death
   04210 Apoptosis
    100337999
   04215 Apoptosis - multiple species
    100337999
   04217 Necroptosis
    100337999
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100337999
   04530 Tight junction
    100337999
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100337999
   04621 NOD-like receptor signaling pathway
    100337999
   04622 RIG-I-like receptor signaling pathway
    100337999
   04625 C-type lectin receptor signaling pathway
    100337999
   04660 T cell receptor signaling pathway
    100337999
   04658 Th1 and Th2 cell differentiation
    100337999
   04659 Th17 cell differentiation
    100337999
   04657 IL-17 signaling pathway
    100337999
   04664 Fc epsilon RI signaling pathway
    100337999
  09152 Endocrine system
   04910 Insulin signaling pathway
    100337999
   04920 Adipocytokine signaling pathway
    100337999
   04912 GnRH signaling pathway
    100337999
   04914 Progesterone-mediated oocyte maturation
    100337999
   04917 Prolactin signaling pathway
    100337999
   04926 Relaxin signaling pathway
    100337999
   04935 Growth hormone synthesis, secretion and action
    100337999
  09156 Nervous system
   04728 Dopaminergic synapse
    100337999
   04723 Retrograde endocannabinoid signaling
    100337999
   04722 Neurotrophin signaling pathway
    100337999
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100337999
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100337999
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100337999
   05208 Chemical carcinogenesis - reactive oxygen species
    100337999
   05231 Choline metabolism in cancer
    100337999
  09162 Cancer: specific types
   05210 Colorectal cancer
    100337999
   05212 Pancreatic cancer
    100337999
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100337999
   05170 Human immunodeficiency virus 1 infection
    100337999
   05161 Hepatitis B
    100337999
   05171 Coronavirus disease - COVID-19
    100337999
   05162 Measles
    100337999
   05167 Kaposi sarcoma-associated herpesvirus infection
    100337999
   05169 Epstein-Barr virus infection
    100337999
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100337999
   05135 Yersinia infection
    100337999
   05133 Pertussis
    100337999
   05152 Tuberculosis
    100337999
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100337999
   05142 Chagas disease
    100337999
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100337999
   05012 Parkinson disease
    100337999
   05016 Huntington disease
    100337999
   05017 Spinocerebellar ataxia
    100337999
   05020 Prion disease
    100337999
   05022 Pathways of neurodegeneration - multiple diseases
    100337999
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100337999
   05418 Fluid shear stress and atherosclerosis
    100337999
   05415 Diabetic cardiomyopathy
    100337999
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100337999
   04936 Alcoholic liver disease
    100337999
   04932 Non-alcoholic fatty liver disease
    100337999
   04931 Insulin resistance
    100337999
   04933 AGE-RAGE signaling pathway in diabetic complications
    100337999
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100337999
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100337999
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100337999
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100337999
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 100337999
NCBI-ProteinID: XP_017202927
Ensembl: ENSOCUG00000010663
LinkDB
Position
15:complement(62662369..62990547)
AA seq 464 aa
MSLHFLYYCSEPTLDVKLAFCQGFDKQVDVSYIAKYYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACSSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIDEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLHPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttcttatactactgcagtgaaccaaccttggatgtgaaacttgccttt
tgtcagggatttgataaacaagtggatgtgtcatatattgccaaatattacaacatgagc
aaaagcaaagtggacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaacctaaagcctattggctctggggctcagggaatagtttgtgct
gcctatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggaattccaa
gatgtctacctggtcatggaactgatggacgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctctatcagatgttgtgtggcattaagcacctc
cactctgctggaattatccacagggatttaaaacccagtaacattgtagtcaaatccgat
tgcacgttgaaaatcctcgactttggactggccaggacagcatgctccagcttcatgatg
actccgtatgtggtgacacgttattacagagccccagaggtcatcctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatatcgaccagtggaacaaagtcattgagcaactagga
acgccgtgtccagaattcatgaagaaattgcagcctacagtaagaaactatgtggagaac
cggcccaagtatgcgggactcaccttccccaagctctttccagattccctcttcccagca
gactccgagcacaataagctcaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgacccagcaaagaggatatcggtggatgacgccttacagcatccttacatcaac
gtctggtatgaccccgccgaagtggaagcgcctccacctcagatatacgacaagcagctg
gatgaaagagaacacaccattgacgagtggaaagaacttatctacaaggaagtaatgaat
tcagaagaaaagactaagaatggcgtagtgaaaggacagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccatccatcctcgtctgtcaacgacatctcctccatgtcc
accgaccagaccctggcgtctgacactgacagcagcctggaagcctcggcaggacccctg
ggttgttgcaggtga

KEGG   Oryctolagus cuniculus (rabbit): 100338341
Entry
100338341         CDS       T03373                                 
Name
(RefSeq) eukaryotic translation initiation factor 5A-1
  KO
K03263  translation initiation factor 5A
Organism
ocu  Oryctolagus cuniculus (rabbit)
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:ocu03012]
    100338341
Translation factors [BR:ocu03012]
 Eukaryotic type
  Initiation factors
   eIF-5
    100338341
SSDB
Motif
Pfam: IF5A-like_N eIF-5a EFP_N
Other DBs
NCBI-GeneID: 100338341
NCBI-ProteinID: XP_051681219
LinkDB
Position
19:complement(9453200..9457768)
AA seq 154 aa
MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVG
IDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDGYLSLLQDSGEVREDLRLPEGDLG
KEIEQKYDCGEEILITVLSAMTEEAAVAIKAMAK
NT seq 465 nt   +upstreamnt  +downstreamnt
atggcagatgatttggacttcgagacaggagatgcaggggcctcagccaccttcccaatg
cagtgctcagcattacgtaagaatggctttgtggtgctcaaaggccggccatgtaagatc
gtcgagatgtctacttcgaagactggcaagcatggccatgccaaggtccacctggtcggt
attgacatctttactgggaagaaatatgaagatatctgcccgtcaactcataatatggat
gtccccaacattaaaaggaatgacttccagctgattggcatccaggatgggtacctatcc
ctgctccaggacagtggggaggtgcgagaggacctccgtctgcctgagggagacctcggc
aaggagatcgagcagaagtacgactgtggagaagagatcctgatcacggtgctgtctgcc
atgacagaggaggcagctgttgcaatcaaggccatggcaaaataa

KEGG   Oryctolagus cuniculus (rabbit): 100342664
Entry
100342664         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase 9 isoform X2
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04014  Ras signaling pathway
ocu04024  cAMP signaling pathway
ocu04068  FoxO signaling pathway
ocu04071  Sphingolipid signaling pathway
ocu04137  Mitophagy - animal
ocu04140  Autophagy - animal
ocu04141  Protein processing in endoplasmic reticulum
ocu04210  Apoptosis
ocu04215  Apoptosis - multiple species
ocu04217  Necroptosis
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04510  Focal adhesion
ocu04530  Tight junction
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04722  Neurotrophin signaling pathway
ocu04723  Retrograde endocannabinoid signaling
ocu04728  Dopaminergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04910  Insulin signaling pathway
ocu04912  GnRH signaling pathway
ocu04914  Progesterone-mediated oocyte maturation
ocu04917  Prolactin signaling pathway
ocu04920  Adipocytokine signaling pathway
ocu04926  Relaxin signaling pathway
ocu04930  Type II diabetes mellitus
ocu04931  Insulin resistance
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05010  Alzheimer disease
ocu05012  Parkinson disease
ocu05016  Huntington disease
ocu05017  Spinocerebellar ataxia
ocu05020  Prion disease
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05142  Chagas disease
ocu05145  Toxoplasmosis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05162  Measles
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05200  Pathways in cancer
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05231  Choline metabolism in cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100342664
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100342664
   04012 ErbB signaling pathway
    100342664
   04014 Ras signaling pathway
    100342664
   04310 Wnt signaling pathway
    100342664
   04668 TNF signaling pathway
    100342664
   04068 FoxO signaling pathway
    100342664
   04071 Sphingolipid signaling pathway
    100342664
   04024 cAMP signaling pathway
    100342664
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100342664
   04137 Mitophagy - animal
    100342664
  09143 Cell growth and death
   04210 Apoptosis
    100342664
   04215 Apoptosis - multiple species
    100342664
   04217 Necroptosis
    100342664
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100342664
   04530 Tight junction
    100342664
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100342664
   04621 NOD-like receptor signaling pathway
    100342664
   04622 RIG-I-like receptor signaling pathway
    100342664
   04625 C-type lectin receptor signaling pathway
    100342664
   04660 T cell receptor signaling pathway
    100342664
   04658 Th1 and Th2 cell differentiation
    100342664
   04659 Th17 cell differentiation
    100342664
   04657 IL-17 signaling pathway
    100342664
   04664 Fc epsilon RI signaling pathway
    100342664
  09152 Endocrine system
   04910 Insulin signaling pathway
    100342664
   04920 Adipocytokine signaling pathway
    100342664
   04912 GnRH signaling pathway
    100342664
   04914 Progesterone-mediated oocyte maturation
    100342664
   04917 Prolactin signaling pathway
    100342664
   04926 Relaxin signaling pathway
    100342664
   04935 Growth hormone synthesis, secretion and action
    100342664
  09156 Nervous system
   04728 Dopaminergic synapse
    100342664
   04723 Retrograde endocannabinoid signaling
    100342664
   04722 Neurotrophin signaling pathway
    100342664
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100342664
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100342664
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100342664
   05208 Chemical carcinogenesis - reactive oxygen species
    100342664
   05231 Choline metabolism in cancer
    100342664
  09162 Cancer: specific types
   05210 Colorectal cancer
    100342664
   05212 Pancreatic cancer
    100342664
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100342664
   05170 Human immunodeficiency virus 1 infection
    100342664
   05161 Hepatitis B
    100342664
   05171 Coronavirus disease - COVID-19
    100342664
   05162 Measles
    100342664
   05167 Kaposi sarcoma-associated herpesvirus infection
    100342664
   05169 Epstein-Barr virus infection
    100342664
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100342664
   05135 Yersinia infection
    100342664
   05133 Pertussis
    100342664
   05152 Tuberculosis
    100342664
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100342664
   05142 Chagas disease
    100342664
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100342664
   05012 Parkinson disease
    100342664
   05016 Huntington disease
    100342664
   05017 Spinocerebellar ataxia
    100342664
   05020 Prion disease
    100342664
   05022 Pathways of neurodegeneration - multiple diseases
    100342664
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100342664
   05418 Fluid shear stress and atherosclerosis
    100342664
   05415 Diabetic cardiomyopathy
    100342664
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100342664
   04936 Alcoholic liver disease
    100342664
   04932 Non-alcoholic fatty liver disease
    100342664
   04931 Insulin resistance
    100342664
   04933 AGE-RAGE signaling pathway in diabetic complications
    100342664
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100342664
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100342664
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100342664
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100342664
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 100342664
NCBI-ProteinID: XP_002721353
Ensembl: ENSOCUG00000015542
UniProt: A0A5F9CRG3
LinkDB
Position
Unknown
AA seq 424 aa
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
NT seq 1275 nt   +upstreamnt  +downstreamnt
atgagtgacagtaaatgtgacagtcagttttacagtgtgcaagtggcagactcaacgttc
actgtcctaaaacgttaccagcagttgaaaccaattggctctggagcccaaggaatcgtt
tgtgctgcttttgatacagttcttgggataaatgttgcagtcaagaaactaagccgtcct
tttcaaaatcaaactcatgcaaagagagcttatcgagaacttgtcctgttaaagtgtgtc
aatcataaaaacataattagtttgttaaatgtatttacaccacaaaaaactctagaagaa
tttcaagatgtgtatttggtgatggaattaatggatgctaacctatgtcaggtgattcac
atggagctggaccatgagagaatgtcctaccttctttaccagatgctttgtggcatcaaa
catctgcactcagccgggataattcacagagacttgaagcctagcaacattgtagtgaaa
tcagactgcacccttaagatccttgattttggcctggcccggacagcgtgcaccaatttc
atgatgaccccctatgtggtaacgcggtattatcgggcacctgaagtcatcctgggtatg
ggctacaaagagaacgtggacatctggtctgtcgggtgcatcatggcagaaatggtcctc
cataaagtcctgttcccaggaagagactatattgatcagtggaacaaagtcattgagcag
ctaggaacaccgtccgcagagttcatgaagaaacttcagccaactgtgaggaactatgtg
gaaaacagaccgaagtaccctggaatcaaatttgaagagctctttccagattggatattc
ccatcagaatcagaacgagacaaaataaaaacgagtcaagccagggatctgttatcaaaa
atgttggtgatcgaccccgacaagcggatctctgtggacgaggctctgcgccacccgtac
atcactgtctggtacgatcctgccgaggcagaggcgccaccacctcagatttacgatgcc
caattggaagaaagagaacatgcaattgaggagtggaaagagctaatttacaaagaagta
atggactgggaagaaagaagcaagaatggtgttgtgaaagatcagccttcagatgcagca
gtaagtagcaacgccactccttcccagtcgtcatctatcaatgacatctcatccatgtcc
acggagcagacactggcctcagacacagacagcagtcttgatgcctcaacaggacctctg
gaaggttgtcgatga

KEGG   Oryctolagus cuniculus (rabbit): 100346929
Entry
100346929         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04014  Ras signaling pathway
ocu04024  cAMP signaling pathway
ocu04068  FoxO signaling pathway
ocu04071  Sphingolipid signaling pathway
ocu04137  Mitophagy - animal
ocu04140  Autophagy - animal
ocu04141  Protein processing in endoplasmic reticulum
ocu04210  Apoptosis
ocu04215  Apoptosis - multiple species
ocu04217  Necroptosis
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04510  Focal adhesion
ocu04530  Tight junction
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04722  Neurotrophin signaling pathway
ocu04723  Retrograde endocannabinoid signaling
ocu04728  Dopaminergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04910  Insulin signaling pathway
ocu04912  GnRH signaling pathway
ocu04914  Progesterone-mediated oocyte maturation
ocu04917  Prolactin signaling pathway
ocu04920  Adipocytokine signaling pathway
ocu04926  Relaxin signaling pathway
ocu04930  Type II diabetes mellitus
ocu04931  Insulin resistance
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05010  Alzheimer disease
ocu05012  Parkinson disease
ocu05016  Huntington disease
ocu05017  Spinocerebellar ataxia
ocu05020  Prion disease
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05142  Chagas disease
ocu05145  Toxoplasmosis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05162  Measles
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05200  Pathways in cancer
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05231  Choline metabolism in cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100346929
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100346929
   04012 ErbB signaling pathway
    100346929
   04014 Ras signaling pathway
    100346929
   04310 Wnt signaling pathway
    100346929
   04668 TNF signaling pathway
    100346929
   04068 FoxO signaling pathway
    100346929
   04071 Sphingolipid signaling pathway
    100346929
   04024 cAMP signaling pathway
    100346929
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100346929
   04137 Mitophagy - animal
    100346929
  09143 Cell growth and death
   04210 Apoptosis
    100346929
   04215 Apoptosis - multiple species
    100346929
   04217 Necroptosis
    100346929
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100346929
   04530 Tight junction
    100346929
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100346929
   04621 NOD-like receptor signaling pathway
    100346929
   04622 RIG-I-like receptor signaling pathway
    100346929
   04625 C-type lectin receptor signaling pathway
    100346929
   04660 T cell receptor signaling pathway
    100346929
   04658 Th1 and Th2 cell differentiation
    100346929
   04659 Th17 cell differentiation
    100346929
   04657 IL-17 signaling pathway
    100346929
   04664 Fc epsilon RI signaling pathway
    100346929
  09152 Endocrine system
   04910 Insulin signaling pathway
    100346929
   04920 Adipocytokine signaling pathway
    100346929
   04912 GnRH signaling pathway
    100346929
   04914 Progesterone-mediated oocyte maturation
    100346929
   04917 Prolactin signaling pathway
    100346929
   04926 Relaxin signaling pathway
    100346929
   04935 Growth hormone synthesis, secretion and action
    100346929
  09156 Nervous system
   04728 Dopaminergic synapse
    100346929
   04723 Retrograde endocannabinoid signaling
    100346929
   04722 Neurotrophin signaling pathway
    100346929
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100346929
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100346929
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100346929
   05208 Chemical carcinogenesis - reactive oxygen species
    100346929
   05231 Choline metabolism in cancer
    100346929
  09162 Cancer: specific types
   05210 Colorectal cancer
    100346929
   05212 Pancreatic cancer
    100346929
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100346929
   05170 Human immunodeficiency virus 1 infection
    100346929
   05161 Hepatitis B
    100346929
   05171 Coronavirus disease - COVID-19
    100346929
   05162 Measles
    100346929
   05167 Kaposi sarcoma-associated herpesvirus infection
    100346929
   05169 Epstein-Barr virus infection
    100346929
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100346929
   05135 Yersinia infection
    100346929
   05133 Pertussis
    100346929
   05152 Tuberculosis
    100346929
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100346929
   05142 Chagas disease
    100346929
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100346929
   05012 Parkinson disease
    100346929
   05016 Huntington disease
    100346929
   05017 Spinocerebellar ataxia
    100346929
   05020 Prion disease
    100346929
   05022 Pathways of neurodegeneration - multiple diseases
    100346929
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100346929
   05418 Fluid shear stress and atherosclerosis
    100346929
   05415 Diabetic cardiomyopathy
    100346929
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100346929
   04936 Alcoholic liver disease
    100346929
   04932 Non-alcoholic fatty liver disease
    100346929
   04931 Insulin resistance
    100346929
   04933 AGE-RAGE signaling pathway in diabetic complications
    100346929
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100346929
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100346929
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100346929
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100346929
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 100346929
NCBI-ProteinID: XP_051693488
Ensembl: ENSOCUG00000002873
UniProt: G1TPJ7
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFERLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVISGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAPA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagatcggagattctacattc
acagtcctgaagcgatatcagaatctaaaacctataggttctggagctcaaggaatagtc
tgtgcagcttatgatgccattcttgaaagaaatgttgccatcaagaagctaagccggccg
tttcagaatcaaacgcatgctaagagggcctacagagagctggttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatctctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcgaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactccgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaaaatccttgactttggactggccaggactgcaggaacaagcttt
atgatgacgccttatgtggtgactcgctactacagagcgcctgaggtcatcctgggcatg
ggctacaaggagaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
ctgggaacaccatgtcctgagttcatgaagaaactgcaaccaacagtaaggacttacgtg
gaaaacagacctaagtatgccggatatagctttgagaggctcttccccgatgtgcttttc
ccagctgactcggaacacaacaagcttaaagccagtcaggcaagggatttgctctctaaa
atgctggtgatagatgcatctaagaggatctctgtagacgaagctctccagcacccatac
atcaatgtctggtacgatccctctgaagcagaagccccaccaccaaagattcctgacaaa
cagttagacgaaagggaacacacgatagaagaatggaaagaattgatatacaaggaagtg
atggatttggaagaaagaaccaagaatggagttatacgagggcagccctctcctttaggt
gcagcagtgatcagtggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagacccgactttggcctcggatacagacagcagtctggaagccccagct
gggcctctgggctgctgtagatga

DBGET integrated database retrieval system