KEGG   Oryctolagus cuniculus (rabbit): 100008904
Entry
100008904         CDS       T03373                                 
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04015  Rap1 signaling pathway
ocu04020  Calcium signaling pathway
ocu04024  cAMP signaling pathway
ocu04072  Phospholipase D signaling pathway
ocu04081  Hormone signaling
ocu04082  Neuroactive ligand signaling
ocu04261  Adrenergic signaling in cardiomyocytes
ocu04270  Vascular smooth muscle contraction
ocu04540  Gap junction
ocu04611  Platelet activation
ocu04713  Circadian entrainment
ocu04714  Thermogenesis
ocu04724  Glutamatergic synapse
ocu04726  Serotonergic synapse
ocu04728  Dopaminergic synapse
ocu04730  Long-term depression
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04911  Insulin secretion
ocu04912  GnRH signaling pathway
ocu04913  Ovarian steroidogenesis
ocu04915  Estrogen signaling pathway
ocu04916  Melanogenesis
ocu04918  Thyroid hormone synthesis
ocu04921  Oxytocin signaling pathway
ocu04922  Glucagon signaling pathway
ocu04923  Regulation of lipolysis in adipocytes
ocu04924  Renin secretion
ocu04925  Aldosterone synthesis and secretion
ocu04926  Relaxin signaling pathway
ocu04927  Cortisol synthesis and secretion
ocu04928  Parathyroid hormone synthesis, secretion and action
ocu04934  Cushing syndrome
ocu04935  Growth hormone synthesis, secretion and action
ocu04961  Endocrine and other factor-regulated calcium reabsorption
ocu04962  Vasopressin-regulated water reabsorption
ocu04970  Salivary secretion
ocu04971  Gastric acid secretion
ocu04972  Pancreatic secretion
ocu04976  Bile secretion
ocu05012  Parkinson disease
ocu05030  Cocaine addiction
ocu05031  Amphetamine addiction
ocu05032  Morphine addiction
ocu05034  Alcoholism
ocu05142  Chagas disease
ocu05146  Amoebiasis
ocu05163  Human cytomegalovirus infection
ocu05165  Human papillomavirus infection
ocu05200  Pathways in cancer
ocu05207  Chemical carcinogenesis - receptor activation
ocu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100008904
   04020 Calcium signaling pathway
    100008904
   04072 Phospholipase D signaling pathway
    100008904
   04024 cAMP signaling pathway
    100008904
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100008904
   04081 Hormone signaling
    100008904
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100008904
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100008904
  09152 Endocrine system
   04911 Insulin secretion
    100008904
   04922 Glucagon signaling pathway
    100008904
   04923 Regulation of lipolysis in adipocytes
    100008904
   04912 GnRH signaling pathway
    100008904
   04913 Ovarian steroidogenesis
    100008904
   04915 Estrogen signaling pathway
    100008904
   04921 Oxytocin signaling pathway
    100008904
   04926 Relaxin signaling pathway
    100008904
   04935 Growth hormone synthesis, secretion and action
    100008904
   04918 Thyroid hormone synthesis
    100008904
   04928 Parathyroid hormone synthesis, secretion and action
    100008904
   04916 Melanogenesis
    100008904
   04924 Renin secretion
    100008904
   04925 Aldosterone synthesis and secretion
    100008904
   04927 Cortisol synthesis and secretion
    100008904
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100008904
   04270 Vascular smooth muscle contraction
    100008904
  09154 Digestive system
   04970 Salivary secretion
    100008904
   04971 Gastric acid secretion
    100008904
   04972 Pancreatic secretion
    100008904
   04976 Bile secretion
    100008904
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100008904
   04961 Endocrine and other factor-regulated calcium reabsorption
    100008904
  09156 Nervous system
   04724 Glutamatergic synapse
    100008904
   04728 Dopaminergic synapse
    100008904
   04726 Serotonergic synapse
    100008904
   04730 Long-term depression
    100008904
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100008904
  09159 Environmental adaptation
   04713 Circadian entrainment
    100008904
   04714 Thermogenesis
    100008904
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100008904
   05207 Chemical carcinogenesis - receptor activation
    100008904
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100008904
   05165 Human papillomavirus infection
    100008904
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100008904
   05142 Chagas disease
    100008904
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100008904
  09165 Substance dependence
   05030 Cocaine addiction
    100008904
   05031 Amphetamine addiction
    100008904
   05032 Morphine addiction
    100008904
   05034 Alcoholism
    100008904
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100008904
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100008904
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100008904
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ocu04147]
    100008904
   04031 GTP-binding proteins [BR:ocu04031]
    100008904
Exosome [BR:ocu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100008904
  Exosomal proteins of other body fluids (saliva and urine)
   100008904
  Exosomal proteins of colorectal cancer cells
   100008904
  Exosomal proteins of bladder cancer cells
   100008904
GTP-binding proteins [BR:ocu04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    100008904
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA GTP_EFTU
Other DBs
NCBI-GeneID: 100008904
NCBI-ProteinID: XP_002721850
Ensembl: ENSOCUG00000017968
UniProt: A0A5F9DVF8
LinkDB
Position
Unknown
AA seq 977 aa
MGLRYCLDGNNMSGQRHLPPEVGEQPPQPALEAPGPAAPGAGPGPAEEMETQPPASEPVP
AQAGAEACEPPEVSGGTLEGLAVAADQEFGGDGGYSPPPEEAMPFEVQQPSVGGFWPTPG
PIAGLEASVDPGVSGSAGPGLGGYSPPPEEAMPFEFEEPAGQGGCSQPASGVPDLAPGGT
DLGVPGAPPGKSGALRPASAGLGGGYSPPPEEAMPFQLDGEAFGDDSPPPGLPRALPQVA
NGDGGSSAAIAVPSAVCLAPATDAPPLWVPEAVRAAANFAGASPPMEIAGPPLEMRSAPV
GVDDAPVSMDSPPIASDGPPIKVSGAPDKRERGERPPVEGEAAEMEGGSVSASAEKGEVP
SPGDGASGAPAGAAPAAGAAPAAPAEPEAGGAPAAPGTAAAGAAPADAEADADTRAAPGA
AAAPDAGAAPAAGGAPGAPAEHAAAAGAPQAAPAAPASGARRRLHLLRPPSPEIQAADPP
TPRPARAAAWRGRAERGRSRRRYDDEGSTSGDADSSSGDESEERAAGCFHWFQRRTRRRR
KPQRNLLRNFLVQAFGGCFGGRSESPQPKPASPSKAKKVSLAEKRRQMRREAMEKRAQKR
AEKKRSRLIDKQLQAEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDA
QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNV
PDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDL
LRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVI
REDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFAR
YTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFN
DCRDIIQRMHLRQYELL
NT seq 2934 nt   +upstreamnt  +downstreamnt
atgggcctgcgctactgcctcgacggcaataatatgtcaggacaacgccatctcccccct
gaagtcggggagcagcctccacagccagccttggaggccccagggccagctgcccccggt
gctgggcctggcccagccgaagagatggagacccagccgcctgccagcgagcccgtcccc
gcacaggctggcgccgaggcctgtgaaccccctgaggtctccgggggcaccctggagggc
ctcgccgtggcagctgaccaggaattcggaggcgatggaggctacagcccacctcccgag
gaagccatgccttttgaggtccagcagcccagcgtgggaggcttctggcccaccccaggg
cccatcgcaggcctcgaggcctctgtggatcccggagtctcgggcagtgccgggcctggc
ctgggaggctacagccccccaccagaagaagccatgccctttgagttcgaggagcctgct
ggccagggaggctgcagccagccagcatcgggggtccccgacctcgctcccggtggcaca
gacctgggggtccctggagctcctcccgggaagtccggggcgctcaggcctgccagcgct
ggccttggaggaggctatagccctccccccgaggaggctatgccatttcagcttgatgga
gaggcctttggggacgacagcccaccccccgggctcccccgagcgctcccacaagttgcc
aacggcgacggtggcagcagcgcggcaatcgcggtcccgagtgcggtctgcctcgctccc
gccaccgacgcgccacccctctgggtcccagaggctgtcagagctgctgctaacttcgcg
ggcgccagccccccgatggagatcgccggacccccgctcgagatgcgcagcgcccccgtc
ggggtcgacgacgctcccgtcagcatggacagccccccaatcgcgagtgatggcccgccc
atcaaggtctccggagccccagataagagggagcgcggcgagagacccccagttgaggga
gaagcagccgagatggaaggaggctcggtcagcgcctctgcggagaaaggagaagtcccc
tctccgggggacggagcctcgggcgccccagctggggccgctcccgccgccggagccgct
cccgccgccccggcggagcccgaagccgggggagccccggccgctcctggcactgcggcc
gccggggcagccccggccgatgccgaagccgacgccgacacccgcgcagcccccggcgcc
gcagccgctcctgatgccggggcagcccctgccgccggtggagcccctggtgccccggcc
gagcacgccgcagccgccggggccccccaggcagcccccgccgcgcctgcctccggggcc
agacgcaggctccatctgctcagaccccccagccccgagatccaggctgctgacccgcct
actccgcggcctgctcgcgcggctgcctggcggggcagagctgagcgcggccgaagccgc
cgccgctacgacgacgaggggtcgaccagcggcgacgccgactcctccagcggggacgag
tccgaagagcgggccgccggctgcttccactggttccagcgccgcacacgccgccgccgc
aagccccagcgcaacttgctccgcaacttcctcgtgcaggctttcgggggctgcttcggt
ggtcgatctgagagcccccagcccaagcccgcgagccccagcaaggccaagaaggtttct
ctggcagagaagcgccgacagatgcgcagggaggccatggagaagcgcgcccagaagcgc
gccgagaagaaacgcagcaggctcatcgacaagcagctgcaggccgagaagatgggctac
atgtgcactcaccgcctgctgcttctaggtgctggagagtctggtaaaagcaccatcgtg
aagcagatgaggatcctgcatgttaatgggtttaatggagagggcggcgaagaggacgcg
caggctgccaggagcaacagcgatggtgagaaggcaacgaaggtgcaggacatcaaaaac
aacctgaaggaggccatcgaaaccatcgtggccgccatgagcaacctggtgcctccggtg
gagctggccaaccctgagaaccagttcagagtggactacattctgagcgtgatgaacgtg
cccgactttgatttccctcccgagttctacgagcacgccaaggctctgtgggaggacgaa
ggagtgcgggcctgctacgagcgctccaacgagtaccagctgattgactgcgcccagtac
ttcctggacaagattgatgtcatcaagcaggccgactacgtgcccagcgaccaggacctg
ctgcgctgccgtgtcctgacctctggaatctttgagaccaagttccaggtggacaaagtc
aacttccacatgttcgatgtgggcggccagcgcgacgagcgccgcaagtggatccagtgc
ttcaacgacgtgactgccatcatcttcgtggtggccagcagcagctacaacatggtcatc
cgcgaggacaaccagaccaaccgtctgcaggaggcgctgaacctcttcaagagcatctgg
aacaacagatggctgcgcaccatctccgtgattctgttcctcaacaagcaagacctgctg
gctgagaaggtgctggctgggaaatccaagattgaggactactttccagaattcgctcgc
tacactactcctgaggatgctactcccgagcccggagaggacccacgcgtgacccgggcc
aagtacttcatccgcgacgagttcctgagaatcagcaccgctagtggagatgggcgccac
tactgctaccctcacttcacctgcgctgtggacacggagaacatccgccgcgtgttcaac
gactgccgtgacatcatccagcgcatgcacctgcgtcagtacgagctgctctaa

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