Oryctolagus cuniculus (rabbit): 100008979
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Entry
100008979 CDS
T03373
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B
KO
K04849
voltage-dependent calcium channel N type alpha-1B
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu04010
MAPK signaling pathway
ocu04020
Calcium signaling pathway
ocu04721
Synaptic vesicle cycle
ocu04723
Retrograde endocannabinoid signaling
ocu04725
Cholinergic synapse
ocu04726
Serotonergic synapse
ocu04727
GABAergic synapse
ocu04728
Dopaminergic synapse
ocu04930
Type II diabetes mellitus
ocu05016
Huntington disease
ocu05020
Prion disease
ocu05022
Pathways of neurodegeneration - multiple diseases
ocu05032
Morphine addiction
ocu05033
Nicotine addiction
ocu05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100008979 (CACNA1B)
04020 Calcium signaling pathway
100008979 (CACNA1B)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
100008979 (CACNA1B)
04725 Cholinergic synapse
100008979 (CACNA1B)
04728 Dopaminergic synapse
100008979 (CACNA1B)
04726 Serotonergic synapse
100008979 (CACNA1B)
04723 Retrograde endocannabinoid signaling
100008979 (CACNA1B)
04721 Synaptic vesicle cycle
100008979 (CACNA1B)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100008979 (CACNA1B)
09164 Neurodegenerative disease
05016 Huntington disease
100008979 (CACNA1B)
05020 Prion disease
100008979 (CACNA1B)
05022 Pathways of neurodegeneration - multiple diseases
100008979 (CACNA1B)
09165 Substance dependence
05032 Morphine addiction
100008979 (CACNA1B)
05033 Nicotine addiction
100008979 (CACNA1B)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100008979 (CACNA1B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ocu04040
]
100008979 (CACNA1B)
Ion channels [BR:
ocu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100008979 (CACNA1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Phage_TAC_15
Motif
Other DBs
NCBI-GeneID:
100008979
NCBI-ProteinID:
NP_001075660
Ensembl:
ENSOCUG00000012674
UniProt:
Q05152
Structure
PDB
PDBj
LinkDB
All DBs
AA seq
2339 aa
AA seq
DB search
MVRFGDELGGRYGGAGGAERARGGGAGGAGGPGPGGLPPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGIFCFEAGIKILALGFVLHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDPDPVGDFPCGKEAPARLCEGDTECREYWAGPNFGITNFDNI
LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
AAKKSRSDLIQAEEGEGRLTGLCAPGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
KAQSFYWTVLCVVALNTLCVAMVHYNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPR
SYFRSSFNCFDFGVIVGSIFEVVWAAVKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLV
VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFKDETPTTNFDTFPAAILTVFQI
LTGEDWNAVMYHGIESQGGVSRGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
LRASCEALYSEMDPEERLRYATARHLRPDVKTHLDRPLVVEPGRDAPRGPPGGKSRPDGS
EAPEGADPPRRHHRHRDKDKAPATVPSAGEQDRAEALRAEGGELGPREERGRPRRSRSKE
APGAPEVRSDRGRGPCPEGGRRHHRRGSPEEAAEREPRRHRAHRHGPDPGKEGPASGTRG
ERRARHRTGPRACPREAESSEEPARRHRARHKAPPTQETAEKDKEAAEKGGEATEAEKDK
EARNHQPKELPCDLEAIGMLGVGAVHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDTS
TTVHIPVTLTGPPGETTVVPSGNVDLESQAEGKKEVETSDVMRSGPRPIVPYSSMFCLSP
TNLLRRCCHYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKYMDYIFTGVFT
FEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDISTIKSLRVLRV
LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
ERACIDFAISARPLTRYMPQNKQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
ANNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIG
MQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSSRACDEHSNAS
ECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYD
PAACGRISYSDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISSEDMTVHFTSTLMA
LIRTALDIKLAPAGTKQHQCDAELRKEISCVWANLPQKTLDLLVPPHKPDEMTVGKVYAA
LMIFDFYKQNKTSRDQTQQAPGGLSQLGPVSLFHPLKATLEQTQPALRGARAFLRQKSSA
SLSNGGAVQTQESGIKESVSWGTQRTQDVLCEARAPLERGHSAEIPVGQPGTLAVDVQMQ
NMTLSGPDAEPQPGLESQGRAASMPRLAAETQPAPDASPMKRSISTLAPRPHTARLGSTA
LDRPAPSQAPHHHHHRCHRRRDRKQRSLEKGPSLSADTDGAPDSTVGPGLPTGEGPPGCR
RERERRQERGRSQERRQPSSSSSEKHRFYSCDRFGGREPPQPKPSLSSHPTSPTAGQEPG
PHPQGSGSVHGSPLLSTSGASTPGRGRRQLPQTPLTPRPSVTYKTANSSPVHFAGAPSGL
PAFSPGRLSRGLSEHNALLQRDPLSRPLAPGSRIGSDPYLGQRLDSEAPARALPEDAPAF
EETAASNSGRSSRTSYVSSLTSQPPPLRRVPNGYHCTLGLGGGGRARRGCHHPDRDRRC
NT seq
7020 nt
NT seq
+upstream
nt +downstream
nt
atggtccgcttcggggacgagctgggcggccgctatgggggcgcgggcggcgcggagcgg
gcccggggcggcggggccggcggggctggcggcccgggccccggggggctgccgccgggc
cagcgggtcctctacaaacagtcgatcgcgcagcgcgcgcggaccatggcgctgtacaac
cccatcccggtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgag
gacaacgtcgtccgcaaatacgccaagcgcatcaccgagtggcctccgttcgagtacatg
atcctggccaccatcatcgccaactgcatcgtgctggccctggagcagcacctccctgac
ggggacaagacgcctatgtccgagcgcctggatgacaccgagccctacttcattgggatc
ttctgcttcgaggcggggatcaagatcctggccctgggctttgttctgcacaagggctcc
tatctgcggaacggctggaacgtcatggacttcgtggtagtcctcacggggattcttgcc
acagccggaaccgacttcgacctgcgaacgctgagggctgtgcgtgtgctaaggcccctg
aagctggtgtctgggattccgagcttgcaggtggtgctcaagtccatcatgaaggccatg
gtcccgctgctgcagatcgggctgctgctcttcttcgccatcctcatgtttgccatcatc
ggcctcgagttctacatgggcaagttccacaaggcctgcttccccaacagcacagaccca
gatcccgtgggtgacttcccctgtggcaaggaggccccggcccggctctgtgagggagac
acggagtgccgggagtactgggccggacccaactttggtatcaccaactttgacaacatc
ctgtttgccatcttgaccgtgttccagtgcatcaccatggagggctggactgacatcctc
tacaatacaaacgatgcagccggcaacacgtggaactggctctacttcatccctctcatc
atcatcggctccttcttcatgctcaacctggtgctgggtgtgctctcaggagagtttgct
aaggagcgcgagagagtggagaaccgccgcgccttcctgaagctccggcggcagcagcag
attgagcgggagctcaacgggtacctggagtggatcttcaaggctgaggaagtcatgctg
gctgaggaggacaggaacgcagaggagaagtcccctctggatgcagtgttgaagagagca
gctgccaagaagagcagaagcgacctgatccaggccgaggagggggagggccggctcaca
ggcctctgtgctcccggttccccgttcgcccgtgccagcctgaaaagcgggaagacggag
agctcgtcgtacttccggaggaaggagaagatgttccgcttcttcatccggcgcatggtg
aaggcacagagcttctactggacggtgctgtgtgtggtggcactgaacacactgtgcgtg
gccatggtgcactacaaccagccgcagcggctcaccacggcattgtactttgcagagttt
gttttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggcccagg
agctacttccggtcctccttcaactgttttgactttggggtcatcgtgggcagtatcttt
gaagtggtctgggctgctgtcaagccagggacctccttcgggatcagtgttctgcgggct
ctgcgcttactgagaatcttcaaggtcaccaaatactggaactccctacggaacctggtg
gtgtctctgctcaactccatgaagtccatcatcagcctcctcttcctgctcttcctgttc
attgttgtctttgctctgctggggatgcagctgtttggaggccagttcaactttaaagac
gagaccccaacgaccaactttgacaccttccctgctgctatcctcaccgtcttccagatc
ctgaccggagaggactggaatgcggtcatgtaccacgggatcgagtcgcaaggtggcgtc
agcagaggaatgttctcctccttctacttcattgtcctcactctgtttgggaactacacc
ctgctgaatgtcttcctggccattgctgtggacaaccttgccaatgctcaggagctgacc
aaggatgaagaggagatggaagaagcagccaatcagaaactcgccttgcagaaggccaag
gaagtggctgaagtcagccccatgtctgctgcgaacatctccattgccgccaggcagcag
aactcggccaaagcgcgctcggtgtgggagcagcgagccagccagctgcggctgcagaac
ctgagggccagctgcgaggcgctgtacagcgagatggaccccgaggagaggctgcgctac
gccaccgcgcgccacctgcggcccgacgtgaagacgcacctggaccggccgctggtggtt
gagcccggccgcgacgctccgcggggccccccgggggggaagtcccggccggatggctcg
gaggcccccgagggtgcggatcccccgcgcaggcatcaccggcaccgagacaaggacaag
gctcccgccacggtcccctcggcgggggaacaggacagagccgaagctctgagggcagag
ggcggggagctggggccccgcgaggagcgggggcggccacgccgcagccgcagcaaggag
gccccgggcgccccggaggtgcgcagcgatcgcggccgtggcccgtgtcctgaaggtggt
cggcgccaccaccggcgcgggtcaccggaggaggcagctgagagggagccccgccgccac
cgcgcgcaccggcacgggcccgacccgggcaaggagggcccagcgtccgggaccaggggc
gagcggcgcgcacgacaccgcacgggcccccgggcgtgcccccgggaggctgagagcagc
gaggagcctgcgcggcggcaccgggctcggcacaaggcgccgcccacccaggagaccgcg
gagaaggacaaggaggctgccgagaaggggggcgaggccacggaggccgagaaggacaag
gaggctcggaaccaccagcccaaggagctgccctgtgacctggaggccatcggcatgctg
ggagtgggcgctgtgcatacgctgcccagcacctgtctgcagaaggtggaggagcagcca
gaggatgcggacaaccagcggaacgtcacccgcatgggtagtcagcccccggacaccagc
accactgtgcacattcctgtgacgctgaccggcccccccggggagaccacggtagtgccc
agtggaaacgtggacctggaaagtcaagcagaggggaagaaggaggtggaaaccagcgat
gtgatgaggagcggccctcggcccattgtcccgtacagttccatgttctgtttaagccca
accaacctgctgcgccgctgctgccactacattgtgaccatgcgatacttcgagatggtc
atcctcgtggtcatcgccctgagcagcatcgccctggctgccgaggaccccgtgagaaca
gactctcccaggaataatgctctgaagtacatggactacatcttcacaggcgtcttcacc
ttcgagatggtgataaagatgatcgatttgggactgctgctacaccctggagcctatttc
cgggatctgtggaacattctggacttcattgtggtcagtggggccctggtggcatttgct
ttctcaggatccaaagggaaagacatcagcaccatcaaatccctgagagtcctgcgtgtg
ctgcggccactcaagaccatcaagcggctgcccaagctcaaggccgtgtttgactgtgtg
gtgaactcactgaaaaacgtcctcaacatcctgatcgtctacatgctcttcatgttcatc
tttgccgtcattgccgtgcagctcttcaaagggaagttcttctactgcacggacgaatcc
aaggagctggagcgtgactgcaggggtcagtatttggattatgagaaggaggaagtggaa
gctcaaccgaggcagtggaagaaatatgacttccactatgacaacgtgctctgggctctg
ctaacgctcttcacggtgtccacaggggaagggtggcccatggtgctgaaacactctgtg
gatgccacctacgaggagcagggcccgagccccgggtaccgcatggagctctccatcttc
tacgtggtctactttgtggtctttcccttcttctttgtcaacatcttcgtggccttgatc
atcatcaccttccaggagcagggggacaaggtgatgtccgagtgcagcctggagaagaac
gagagggcttgcatcgactttgccatcagcgccagacccctgacgcggtacatgccccag
aacaagcagtcgttccagtataagacgtggacgttcgtggtgtccccaccttttgagtac
ttcatcatggctatgatcgccctcaacactgtggtgctgatgatgaagttctacgatgcg
ccgtacgagtatgagctaatgctgaaatgcctgaacatcgtgttcacgtccatgttctcc
atggagtgtgtgctgaagatcatcgccttcggggtgctgaactatttcagagatgcctgg
aatgtctttgactttgtcacggtgttgggaagtattactgatattttggtaacagagatt
gcgaacaacttcatcaacctcagcttcctgcgcctgttccgggccgcgcggctcatcaag
ctgctgcgccagggctacaccatccgcatcctgctttggaccttcgtgcagtccttcaag
gcgctgccctacgtgtgtctcctcatcgccatgctcttcttcatctacgccatcattggc
atgcaggtttttgggaacatcgccctggacgatgacaccagcatcaacaggcacaataac
ttccggacgtttctgcaggccttgatgttgctgttcaggagcgccacgggggaggcctgg
cacgagataatgctgtcgtgcctcagcagccgggcctgcgacgagcactccaatgccagc
gagtgcggcagcgactttgcctacttttacttcgtctccttcatcttcctctgctccttt
ctgatgttgaacctctttgtggctgtgatcatggacaattttgagtaccttacacgggac
tcttccatcttagggcctcaccacctggatgagttcatccgggtctgggctgaatacgac
ccggccgcgtgtgggcgcatcagttacagtgacatgtttgagatgctgaagcacatgtcc
ccacccctggggctggggaagaagtgccctgctcgagtcgcgtacaagcgcctggtccgc
atgaacatgcccatctccagtgaggacatgacggtgcacttcacatccacgctgatggct
ctcattcggacagcgctggacatcaagctggcaccagctgggaccaagcagcaccagtgc
gacgcagagctgaggaaggagatttcctgtgtgtgggccaatctgccccagaagaccctg
gacttactggtaccaccccataagcctgacgagatgacggtgggcaaagtctatgcagct
ctgatgatcttcgacttctacaaacagaacaaaaccagcagagaccagactcagcaagcc
cccggaggcctgtcccagctgggccccgtgtccctgttccacccgctgaaggccacgctg
gagcagactcagccggcgctgcgtggagcccgggctttcctgcggcagaagagttctgcc
tccctgagcaacggcggggccgtacaaacccaggagagcggcatcaaggaatcggtttct
tggggcactcagaggacccaggatgtgctttgcgaggccagggcacccctggagcggggc
cactcagctgagatcccagtcgggcagcctgggacactggctgtagatgtccagatgcag
aacatgactctgagtggccctgacgccgagccgcagccagggctggagagccagggccga
gccgcctccatgccccgcctggccgcagaaacacagcccgcgcctgacgccagccccatg
aagcgctccatctccacgctggccccgcgcccccacacggcccggctcggcagcaccgcg
ctggaccgcccagcccccagccaggccccgcaccatcaccaccaccgctgccaccgccgc
agggacaggaagcagcggtccctggagaagggtcccagcctgtctgctgacacagatggg
gcccccgacagcacggtggggccaggactgcccacgggggagggcccccccggctgcagg
cgggagcgggagcgcaggcaggagcggggccggtcccaggagcggaggcagccctcgtcc
tcctcctcggagaagcatcgcttctactcctgtgaccgcttcgggggccgcgaaccccca
cagcccaagccctccctcagtagtcaccccacgtcgccgacggccgggcaggagccggga
ccccacccgcaggggagtggttcggttcacgggagccccctgctgtccacatctggtgct
agcaccccgggccgggggcggaggcagctcccccagacccccttgaccccccgccccagc
gtcacctacaagacggccaactcctcgcctgtccacttcgccggggcaccgagcggcctc
cccgccttctcccccggccggctcagccggggcctctcagaacacaacgccctgctgcag
agggacccgctcagccggcccctggcgcccggctcgcgcatcggctccgacccctacctg
gggcagcggctggacagcgaggcgcccgcccgtgccctgcccgaggacgcgcccgccttt
gaggagaccgcggccagcaactcgggccgctcctcccggacctcgtacgtgtcctcactg
acctcgcagcccccgccgctgcgccgcgtgcccaacggctaccactgcactctggggctg
ggcgggggcggccgggcgcggcgcggctgccaccaccccgaccgcgaccgccggtgctag
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integrated database retrieval system
