Oryctolagus cuniculus (rabbit): 100009114
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Entry
100009114 CDS
T03373
Symbol
ALOX15
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX15
KO
K00460
arachidonate 15-lipoxygenase [EC:
1.13.11.33
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00590
Arachidonic acid metabolism
ocu00591
Linoleic acid metabolism
ocu01100
Metabolic pathways
ocu04148
Efferocytosis
ocu04216
Ferroptosis
ocu04217
Necroptosis
ocu04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
100009114 (ALOX15)
00591 Linoleic acid metabolism
100009114 (ALOX15)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100009114 (ALOX15)
09143 Cell growth and death
04216 Ferroptosis
100009114 (ALOX15)
04217 Necroptosis
100009114 (ALOX15)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100009114 (ALOX15)
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.33 arachidonate 15-lipoxygenase
100009114 (ALOX15)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
100009114
NCBI-ProteinID:
NP_001075751
UniProt:
P12530
Structure
PDB
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Position
19:complement(9791738..9800636)
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AA seq
663 aa
AA seq
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MGVYRVCVSTGASIYAGSKNKVELWLVGQHGEVELGSCLRPTRNKEEEFKVNVSKYLGSL
LFVRLRKKHFLKEDAWFCNWISVQALGAAEDKYWFPCYRWVVGDGVQSLPVGIGCTTVGD
PQGLFQKHREQELEERRKLYQWGSWKEGLILNVAGSKLTDLPVDERFLEDKKIDFEASLA
WGLAELALKDSLNVLAPWKTLDDFNRIFWCGRSKLARRVRDSWQEDSLFGYQFLNGANPM
LLRRSVQLPARLVFPPGMEELQAQLEKELKAGTLFEADFALLDNIKANVILYCQQYLAAP
LVMLKLQPDGKLMPMVIQLHLPKIGSSPPPLFLPTDPPMVWLLAKCWVRSSDFQVHELNS
HLLRGHLMAEVFTVATMRCLPSIHPVFKLIVPHLRYTLEINVRARNGLVSDFGIFDQIMS
TGGGGHVQLLQQAGAFLTYRSFCPPDDLADRGLLGVESSFYAQDALRLWEIISRYVQGIM
GLYYKTDEAVRDDLELQSWCREITEIGLQGAQKQGFPTSLQSVAQACHFVTMCIFTCTGQ
HSSIHLGQLDWFTWVPNAPCTMRLPPPTTKDATLETVMATLPNLHQSSLQMSIVWQLGRD
QPIMVPLGQHQEEYFSGPEPRAVLEKFREELAIMDKEIEVRNEKLDIPYEYLRPSIVENS
VAI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggtgtctatcgcgtctgcgtgtccaccggggcctcgatctacgcgggctccaaaaac
aaagtggagctgtggctggttggccagcacggagaggtggagctcgggtcgtgcctgcgg
cccacacggaacaaggaggaggaattcaaggtgaacgtttccaagtacctgggatcgctg
ctgttcgtgagactgcgcaaaaaacactttctcaaggaagacgcctggttttgcaactgg
atctccgtgcaggccctcggggccgctgaggacaagtactggttcccgtgctaccgctgg
gtggtgggcgacggcgtccagagcttgccagtgggcattggctgcaccacggtcggggat
ccgcagggcctgtttcagaaacacagagagcaggagctggaagagagaaggaagctgtac
cagtgggggagctggaaggaggggttaatcctgaacgtggcggggtccaagttaactgac
ctccctgtggatgagcgatttctggaggacaagaaaatcgacttcgaggcttcgctggcc
tgggggctggcagagctcgctttgaaggactcgctcaatgttctggctccctggaaaact
ctcgatgacttcaataggattttctggtgcgggcggagcaagctggcgaggcgggtgcgg
gactcctggcaggaggactccttgttcgggtaccagtttctcaatggcgccaaccccatg
ctgctgaggcgctctgtccagcttcctgcccgcctggtgttccctccgggcatggaggag
ctgcaggcccagctggagaaggagctcaaggcaggcacgctgtttgaagccgacttcgcc
ctgctggataacatcaaggccaacgtcatcctgtattgccagcagtacctggctgccccg
ctggtcatgttgaaactgcagcccgatgggaaactcatgcctatggtcatccagctccat
ttgccaaaaatcggatcctccccaccaccgcttttcctgcccacggacccccccatggtc
tggctgctggccaaatgctgggtccgtagctctgacttccaggttcatgagctgaattct
catcttctgaggggacacttgatggccgaggtcttcacggtggccaccatgagatgtctt
ccatccatacatcctgtcttcaagctgatcgtcccccacctgcgatacaccttggagatc
aacgtccgcgccaggaacgggctggtctctgacttcggcatttttgaccagataatgagc
acgggcggcggcggccacgtgcagctgctccagcaagctggagccttcttaacctatcgc
tccttctgtccccctgacgatctggccgaccggggcctgctgggagtcgagtcttccttc
tacgctcaggacgcgctgcggctctgggaaatcatctcccgctacgtgcagggaatcatg
ggcctctactacaaaaccgacgaggctgtgagggacgacctggagctgcagagctggtgc
cgagagatcactgaaatcgggctgcaaggggcccagaagcaagggttccccacctcttta
cagtccgtggcccaggcttgccactttgtcaccatgtgcatcttcacctgcacgggccag
cactcctccatccacctgggccagttggactggttcacgtgggtccctaacgcgccctgc
accatgcggctgcccccgccgaccaccaaggacgcgacgctggagacggtgatggccaca
ctgcccaacttgcatcagtcttctctccagatgtccatcgtctggcagctaggcagggac
cagcccattatggtgcctttgggccagcaccaggaggagtacttctcgggccctgagccc
agggctgtgctggagaagttcagggaggaactggccatcatggataaggaaattgaggtc
cggaatgaaaagctggacataccctatgagtacctgcgccccagcattgtggagaacagt
gtggccatttga
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