Oryctolagus cuniculus (rabbit): 100009243 Help Entry 100009243         CDS       T03373                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00220   Arginine biosynthesis ocu00330   Arginine and proline metabolism ocu01100   Metabolic pathways ocu04020   Calcium signaling pathway ocu04081   Hormone signaling ocu04145   Phagosome ocu04371   Apelin signaling pathway ocu04713   Circadian entrainment ocu04730   Long-term depression ocu04926   Relaxin signaling pathway ocu04970   Salivary secretion ocu05010   Alzheimer disease ocu05014   Amyotrophic lateral sclerosis ocu05022   Pathways of neurodegeneration - multiple diseases ocu05410   Hypertrophic cardiomyopathy ocu05412   Arrhythmogenic right ventricular cardiomyopathy ocu05414   Dilated cardiomyopathy ocu05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     100009243 (NOS1)    00330 Arginine and proline metabolism     100009243 (NOS1)  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04081 Hormone signaling     100009243 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100009243 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     100009243 (NOS1)   09154 Digestive system    04970 Salivary secretion     100009243 (NOS1)   09156 Nervous system    04730 Long-term depression     100009243 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     100009243 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100009243 (NOS1)    05014 Amyotrophic lateral sclerosis     100009243 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     100009243 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100009243 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     100009243 (NOS1)    05414 Dilated cardiomyopathy     100009243 (NOS1)    05416 Viral myocarditis     100009243 (NOS1) Enzymes [BR:ocu01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      100009243 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  100009243 NCBI-ProteinID:  NP_001075854 Ensembl:  ENSOCUG00000014718 UniProt:  O19132 LinkDB All DBs Position 21:15449530..15534686 Genome browser AA seq 1435 aa AA seqDB search MEEHVFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGVASETHVVLILRGPEGFTTNLETTFTGDGTPKTI RVTQPLGAPTKAVDLSHQPPSAGKEQPRPVDGAAGPGSWPQPTQGHGQEAGSPSRANGLA PRTSSQDPAKKSGWAGLQGSGDKNELLKEIEPVLTLLAGGSKAVDGGGPAKAETRDTGVQ VDRDFDAKSHKPLPLGVENDRVFSDLWGKGSAPVVLNNPYSEKEQPPASGKQSPTKNGSP SKCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMFPSQHTRRPEDIRTKEQL FPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASR CVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRV WNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRSRFDVLPLLLQANGNDPELF QIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIG VRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSA TESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPCFEYQPDPWNTH VWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLC EIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFRCALMEMRHPNSL QEERKSYKVRFNSVSSYSDSRKSSGDGPDVRDHFESAGPLANVRFSVFGLGSRAYPHFCA FGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKAN NSLISNDRSWKRNKFRLTYVAEAPGLTQGLSSVHKKRVSAARLLSRQNLQSPKSSRSTIF VRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANQMVKVELLEERNTALG VISNWKDEPRLPPCTVFQAFKYYLDITTPPTPLQLQQFASLASNEKEKQRLLVLSKGLQE YEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAI VSYHTRDGEGPIHHGVCSSWLNRIPADEVVPCFVRGAPSFRLPRNPQVPCILVGPGTAFA PFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQSKIDHIYREEALQAKNKGVFRELYTAYSR EPDKPKKYVQDILQEQLAEQVYRALKEQGGHIYVCGDVTMAADVLKAVQRIMAQQGKLSA EDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4308 nt NT seq  +upstreamnt  +downstreamnt atggaggagcacgtgtttggcgttcagcaaatccagcccaatgtcatctcggtccgtctc tttaagcgcaaggtggggggcctggggttcctggtgaaggagcgcgtcagcaagcccccc gtgatcatctccgacctgattcgaggcggggccgccgagcagagcggccttatccaggcc ggcgacatcattctcgccgtcaacggcaggcccttggtggacctgagctacgacagtgcc ctggaagtgctccggggtgttgcctcggagacccacgtcgtcctcatcctgaggggcccc gagggcttcaccacgaacctggagaccaccttcaccggagacggcacccccaagaccatc cgggtaacccagcccctgggtgcccccaccaaagccgtcgatctatcccaccagccgccg tcggccggcaaagagcagccacggccagtggacggggccgcggggcctggcagctggcct cagcccacccaaggtcacgggcaggaagccggctcaccctcccgcgccaatggcctggcc cccagaacatcaagccaggaccctgccaagaaaagtggctgggcgggcctgcaaggcagt ggcgataagaacgagctcctgaaggagattgagcccgtgctgaccctcctcgccggtggg agcaaggcagttgacggagggggccctgccaaggcggagacgagagacacgggagtccag gtggacagggatttcgatgccaagtcgcacaagcctctgcctcttggcgtggagaacgac cgagtcttcagtgacctgtgggggaagggcagcgcgcctgtggtcctcaacaacccctat tcagagaaggagcagccccctgcctcgggcaaacagtcccccactaagaacggcagcccc tccaagtgcccccgcttcctcaaggtcaagaactgggagacagacgtggttctcactgat accctgcaccttaagagcaccctggaaaccggatgcaccgagcacatatgcatggggtcc atcatgttcccctcccagcacacacggaggccggaagacatccgcacaaaagagcagctc ttccctcttgccaaagaattcatcgatcagtactactcctccatcaaaagatttggctcc aaagcccacatggagagactggaggaggtgaataaggagattgaaagcaccagcacctac cagctcaaggacacggagctcatctacggggccaagcatgcctggcggaacgcctcccgc tgcgtcggcaggatccagtggtccaagctgcaggtgtttgatgcccgagactgcaccaca gctcatggcatgttcaactacatctgcaaccacatcaagtacgccaccaacaaagggaac ctcaggtcggccatcaccatatttccccagaggactgatggcaagcatgacttccgtgtc tggaactctcagctcatccgctacgccggctataagcagcccgatggctccaccctgggg gacccagccaacgtacagttcacagagatctgcatacagcagggctggaagcccccgagg agccgtttcgatgtcctgccgctgctgctccaagccaacggcaatgaccctgagctcttc cagatcccgccggaactggtgctggaagtgcccatcaggcaccccaagtttgagtggttc aaggacctgggactgaagtggtacggcctcccagctgtgtccaacatgctcctggagatt ggcggcctggagttcagcgcctgtcccttcagcggctggtacatgggcacggagatcggt gtccgcgactactgcgacaactcccgctacaacatcctggaggaagtggccaagaagatg aacttggacatgaggaagacgtcctccctgtggaaggaccaagcgctggtggagatcaac atcgccgttctctacagcttccagagcgacaaggtgaccatcgtggaccaccactctgcc actgagtccttcattaagcacatggagaatgagtaccgctgtcgggggggctgccccgcc gactgggtgtggatcgtgccccccatgtcgggcagtatcactcccgtcttccaccaggag atgctcaactaccgactcaccccctgcttcgaataccagcctgatccttggaacacccac gtctggaaaggcaccaatgggacccccacgaagcggcgcgccatcggcttcaagaaactg gcagaagccgtgaagttctcagccaagctgatggggcaggcgatggccaagagggtcaaa gcaacaatcctctatgccacagagaccggcaaatcacaagcctatgccaaaaccctgtgt gagatcttcaagcatgcctttgatgccaaggtgatgtccatggaagaatacgacattgtg cacctggaacacgaaactctggtcctggtggtgaccagcacctttggcaatggagacccc cctgagaacggagagaaattccgctgcgccttgatggaaatgaggcaccccaactctctg caggaggagcggaagagctacaaggttcgcttcaacagcgtctcctcctactcggactcc cgcaagtcatcaggcgatgggcccgacgtcagagaccactttgagagcgctggacccctg gccaatgtgaggttctccgtgttcggcctgggctcacgggcgtaccctcacttctgcgcc ttcggacatgccgtggacaccctcctggaagagctgggaggggagaggatcctgaagatg agagaaggagatgagctctgtgggcaggaagaggccttcaggacctgggccaagaaggtc ttcaaggcggcctgtgacgtgttctgcgtgggggatgacgtcaacatcgagaaggcaaac aattccctgatcagcaacgaccgcagctggaagaggaacaagttccgcctcacctacgtg gccgaagcccccggactgacacaaggcctttccagtgtccacaagaagcgagtctccgcc gctcggctccttagccgtcaaaacctccagagccctaaatccagccgctccaccatcttc gtgcgtctgcacaccaacgggagtcaggagctgcagtaccagcctggggaccacctgggg gtcttccctggcaaccacgaggacctcgtgaacgccctcatcgagcggctggaagacgcg ccccctgccaaccagatggtcaaagtggagctcctggaggagcggaacacagctttgggc gtcatcagtaactggaaagacgagccccgcctgccgccctgcacggtcttccaggccttc aagtactacctggacatcaccacgccgcccacgcccctgcagctgcagcagtttgcctcc ctggccagcaacgagaaagagaagcaacgcctgttggtcctcagcaagggtctgcaggag tacgaggagtggaaatggggcaagaaccccaccatcgtggaggtgctggaggagttcccg tccatccagatgccggccaccctgctgctcacccagctgtccctgctgcagccgcgctac tactccatcagctcctccccagacatgtaccccgacgaggtgcacctcaccgtggccatt gtctcctaccacacccgagatggagaaggaccaattcaccacggtgtgtgctcctcttgg ctcaaccgaatacctgcagacgaggtggtgccctgctttgtgagaggcgcgcccagtttc cgcctgccccggaacccccaagtcccctgcatcctggtggggccgggcaccgcattcgca cctttccggagcttctggcaacagcggcagtttgacatccagcacaaaggaatgagcccc tgccccatggtcctggtgttcgggtgccggcagtccaagatcgatcacatctacagggag gaggcgctccaggccaagaacaagggcgtcttcagagagctgtacacggcctactcccgg gagcccgacaagccgaagaagtacgtgcaggacatcctgcaggagcagctggcggagcag gtgtaccgggccctcaaggagcagggtggccacatctacgtgtgcggggacgtgaccatg gccgccgacgtgctcaaagccgtgcagcgcatcatggctcagcaggggaagctgtcggcc gaggacgccggcgtgttcatcagcaggctgagggatgacaaccggtaccatgaggatatt ttcggagtcaccctgcggacgtacgaagtgaccaaccgccttagatctgagtccatcgcc ttcatcgaggagagcaaaaaagacaccgatgaggttttcagctcctaa

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