Oryctolagus cuniculus (rabbit): 100009471
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Entry
100009471 CDS
T03373
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu02010
ABC transporters
ocu04024
cAMP signaling pathway
ocu04152
AMPK signaling pathway
ocu04530
Tight junction
ocu04971
Gastric acid secretion
ocu04972
Pancreatic secretion
ocu04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100009471 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
100009471 (CFTR)
04152 AMPK signaling pathway
100009471 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
100009471 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
100009471 (CFTR)
04972 Pancreatic secretion
100009471 (CFTR)
04976 Bile secretion
100009471 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
ocu02000
]
100009471 (CFTR)
Enzymes [BR:
ocu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
100009471 (CFTR)
Transporters [BR:
ocu02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
100009471 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_21
AAA_29
T2SSE
AAA_16
RsgA_GTPase
DO-GTPase2
DUF87
MeaB
Zeta_toxin
MMR_HSR1
AAA_30
NTPase_1
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
100009471
NCBI-ProteinID:
NP_001076185
Ensembl:
ENSOCUG00000010733
UniProt:
Q00554
LinkDB
All DBs
Position
7:145770301..146110081
Genome browser
AA seq
1481 aa
AA seq
DB search
MQKSPLEKAGVLSKLFFSWTRPILRKGYRQRLELSDIYQIPSADSADNLSEKLEREWDRE
LASKKKPKLINALRRCFFWRFMFYGILLYLGEVTKAVQPLLLGRIIASYDPDNKVERSIA
IYLGIGLCLLFVVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
ISLLSNNLNKFDEGLALAHFVWISPLQVTLLMGLLWELLQASAFCGLAFLIVLALVQAGL
GRMMMKYRDQRAGKINERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAA
YVRYFNSSAFFFSGFFVVFLSVLPYALTKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMDNVTAFWEEGFGELFEKAKQNNSDRK
ISNGDNNLFFSNFSLLGAPVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEG
KIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVIKACQLEEDISKFTEKDNTV
LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSSYFYGTFSELQSLRPDFSSKLMGYDSFDQFSAERRNS
ILTETLRRFSLEGDASISWNDTRKQSFKQNGELGEKRKNSILNPVNSMRKFSIVPKTPLQ
MNGIEEDSDASIERRLSLVPDSEQGEAILPRSNMINTGPMLQGCRRQSVLNLMTHSVSQG
PSIYRRTTTSARKMSLAPQTNLTEMDIYSRRLSQESGLEISEEINEEDLKECFIDDVDSI
PTVTTWNTYLRYITVHRSLIFVLIWCIVIFLAEVAASLVVLWLFGNTAPQDKENSTKSGN
SSYAVIITNTSSYYFFYIYVGVADTLLALGLFRGLPLVHTLITVSKILHHKMLHSVLQAP
MSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVVGAIAVVSVLQPYIFLATV
PVIAAFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHK
ALNLHTANWFLYLSTLRWFQMRIEMIFVLFFIAVAFISILTTGEGEGRVGIILTLAMNIM
STLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEETKSTKSIKPSSNCQLSKVMIIENQHVK
KDDVWPSGGQMTVKGLTAKYIDSGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR
LLNTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVA
DEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI
TYQIIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENTVRQYESIQKLLSEKSLFRQ
AISSSDRAKLFPHRNSSKHKSRPQITALKEEAEEEVQGTRL
NT seq
4446 nt
NT seq
+upstream
nt +downstream
nt
atgcagaagtcgcctctggagaaggccggcgtcctctccaaactttttttcagctggact
agaccgattttgagaaaaggatacagacaacgcctggaattgtcagacatttaccaaatc
ccttctgctgattctgcagacaacctgtctgagaagctggagagagaatgggatagagag
ctggcttcaaagaaaaaacccaagctcattaatgcccttcggaggtgctttttctggaga
tttatgttctatggaatcttattatatttaggggaagtcaccaaagccgtacagcctctc
ctattggggcgaatcatagcttcctatgatccagacaacaaggtggagcgctccattgcc
atttacctgggcataggtctgtgcttactctttgttgtgaggaccctactcctacaccca
gcaatttttggtcttcatcatattggaatgcagatgagaatagccatgttcagtttgatt
tataagaagactttaaagctgtcaagccgtgttctagataaaataagtattgggcaactt
attagtctcctttccaacaacctgaacaaatttgatgaagggcttgcgctggcccatttc
gtgtggatttcacctctgcaagtgactctgctgatggggctgctctgggaactactacag
gcctctgccttctgcggccttgctttcctaatagtccttgcccttgttcaagccgggcta
gggagaatgatgatgaagtacagggatcagagagctggaaagatcaatgagagactagtg
atcacttcagaaatgattgaaaacatccaatctgttaaagcatactgctgggaggaagcg
atggaaaaaatgattgaaaacctaagacaaacagaactgaaactgacccggaaagcagcc
tacgtgagatacttcaacagctcagccttcttcttctcagggttctttgtggtgttttta
tctgtgcttccttacgcacttaccaaaggaatcatcctgcgcaaaatattcaccaccatc
tcattctgcatcgttctgcgcatggccgttactcggcagttcccctgggctgtgcaaaca
tggtatgactcacttggagcaataaacaaaatccaggatttcttacaaaagcaagaatat
aaaacactggaatacaacttaacaactacagaggtcgtgatggataatgtaacagccttc
tgggaagagggatttggggaattatttgagaaagcaaagcaaaacaatagtgatagaaaa
atctccaatggtgataacaacctcttcttcagtaatttctcacttcttggtgctcctgtc
ttgaaagatatcagcttcaagatagaaagagggcagctgttggcggtggctggatctact
ggtgctggaaagacttcgcttctgatgatgattatgggagagttggagccttcagagggt
aaaattaagcacagtggaagaatatcattctgctctcagttttcctggatcatgcctggc
accattaaagagaacatcatcttcggtgtttcctacgatgagtatagatacaagagtgtc
atcaaagcttgccaactagaagaggacatctccaagtttacagagaaagacaatacagtt
cttggagaaggtggaattactctgagtggaggtcaacgagcaagaatttctttagcaaga
gcagtatacaaagatgctgatttgtacctattggactctccttttggatatctagatgtc
ttaacagaaaaagaaatatttgagagctgtgtctgtaaattgatggccaacaaaactaga
attttggtcacttctaaaatggaacatttaaagaaagctgacaaaatattaattttacat
gaaggcagcagctatttttatggtactttttctgaactccaaagtctacggccggatttt
agctcaaagctcatgggatatgattcttttgaccagtttagtgcagaaagaagaaattca
atcctaactgagaccttacggcgtttctcattagaaggagatgctagcatctcctggaat
gataccagaaaacaatcttttaaacagaatggagagttgggggaaaaacggaagaactct
attctcaatccagtcaactctatgagaaaattttctattgtaccaaaaactcctttacaa
atgaatggcattgaagaagattcggacgcatccatagagcggaggctgtccttggttcca
gattcagaacagggagaggcgattctacctcgaagcaacatgatcaacactggccccatg
ctgcagggctgcaggaggcagtcggttctgaacctgatgacacactcggtcagccaaggt
cccagcatttacagaaggacaaccacatccgcacgaaaaatgtctctggcccctcagaca
aacttgactgaaatggacatatattcaagacggttatctcaagaaagtggcttggaaatt
agtgaagagattaatgaagaagacttaaaggaatgctttattgatgatgtggacagcata
cctacagtgaccacatggaatacataccttcggtatattactgtccacaggagcttgatt
tttgtgctaatttggtgcatagttatttttctagctgaggtggctgcctccttggttgtg
ttgtggctatttggaaacactgctcctcaagacaaagagaatagtacaaaaagtgggaac
agcagctatgctgtgattatcaccaacaccagctcttactactttttttacatttatgtg
ggagtagccgacaccttgcttgcattgggattattcagaggtttgccactggtgcatact
ctaatcacagtgtcgaaaattttacaccacaaaatgttacattctgttcttcaggcgccc
atgtcaacactcaacacattgaaagcaggtgggattcttaatagattctccaaggatata
gccattctggatgatctgctgcctcttaccatatttgacttcatccagttattgttaatt
gtggttggagccatagcagtggtttcggttttacaaccttacatcttcctagcaacagtt
ccagtgatagcagccttcattttattgagagcgtacttcctccatacctcacagcaactc
aagcaactggaatctgaaggtaggagtccaattttcactcatcttgttacaagcttgaaa
ggattatggacacttcgtgcctttggacggcagccttactttgaaactctgttccacaaa
gctctgaatttacacactgccaactggttcttgtatctgtcaacactacgctggttccaa
atgaggatagaaatgatttttgtcctcttcttcattgccgtagccttcatttccatttta
acaacaggtgaaggagaaggaagagttggtattattctaactttagccatgaatatcatg
agtacgttgcagtgggctgtgaactccagcatagatgtagatagcttgatgcgatctgtg
agtcgagtctttaagtttattgacatgccaacagaagaaactaagtctaccaaatccatc
aaaccatccagtaactgccagctatcaaaagttatgattattgagaatcaacatgtgaag
aaagatgacgtctggccctcaggaggccaaatgactgtcaaaggtctcacagcaaaatat
atagacagcggaaatgccatcctggagaacatttccttctcaataagtcctggccagagg
gtgggcctcttaggaagaactggctcagggaagagtactttgttatcagcatttttgaga
ctactgaacactgaaggagaaatccagattgatggtgtgtcttgggattcgatcactttg
cagcagtggagaaaagcctttggagtgatcccacagaaagtatttatcttttctggaaca
tttagaaaaaacttggatccctatgaacaatggagtgatcaagaaatatggaaagttgca
gatgaggttggactcagatctgtaatagaacaatttcctgggaagcttgattttgtcctt
gtggatgggggctatgtcctcagccatggccataagcagttgatgtgcttggccagatct
gttctcagtaaggcaaagatcttgctgcttgatgaacccagtgctcatctggatcctata
acataccaaataattcggagaactctgaaacaagcatttgctgattgcacagtaatcctc
tgtgaacacaggatagaggcaatgttggaatgccaacgatttctggtcatagaagagaac
acagtgcggcagtacgaatccatccagaaattgctgagtgagaagagcctcttccggcag
gccatcagctcctcggacagggcaaagctcttcccccacaggaactcaagcaagcacaag
tctcggccccagatcactgctctgaaggaggaggcagaagaagaagtacaaggaacaagg
ctctag
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