Oryctolagus cuniculus (rabbit): 100009498
Help
Entry
100009498 CDS
T03373
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00220
Arginine biosynthesis
ocu00330
Arginine and proline metabolism
ocu01100
Metabolic pathways
ocu04020
Calcium signaling pathway
ocu04022
cGMP-PKG signaling pathway
ocu04066
HIF-1 signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04370
VEGF signaling pathway
ocu04371
Apelin signaling pathway
ocu04611
Platelet activation
ocu04915
Estrogen signaling pathway
ocu04921
Oxytocin signaling pathway
ocu04926
Relaxin signaling pathway
ocu04931
Insulin resistance
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu05415
Diabetic cardiomyopathy
ocu05417
Lipid and atherosclerosis
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100009498 (NOS3)
00330 Arginine and proline metabolism
100009498 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100009498 (NOS3)
04371 Apelin signaling pathway
100009498 (NOS3)
04066 HIF-1 signaling pathway
100009498 (NOS3)
04020 Calcium signaling pathway
100009498 (NOS3)
04071 Sphingolipid signaling pathway
100009498 (NOS3)
04022 cGMP-PKG signaling pathway
100009498 (NOS3)
04151 PI3K-Akt signaling pathway
100009498 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100009498 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100009498 (NOS3)
04921 Oxytocin signaling pathway
100009498 (NOS3)
04926 Relaxin signaling pathway
100009498 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100009498 (NOS3)
05418 Fluid shear stress and atherosclerosis
100009498 (NOS3)
05415 Diabetic cardiomyopathy
100009498 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100009498 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100009498 (NOS3)
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100009498 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100009498
NCBI-ProteinID:
NP_001076202
Ensembl:
ENSOCUG00000023757
UniProt:
Q6Y5E2
LinkDB
All DBs
Position
13
Genome browser
AA seq
1209 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPASPPPTPPAPDHSPKPSS
NSPPLTRPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTQRRCLGSLVFPRKLQSRPT
QGAPPPEQLLVQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRENELVFGA
KQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQR
GPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQ
VPDEPPELFTLPPELVLEVSLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFS
GWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAK
VTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFR
YQPDPWKGSGAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSY
AQQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMS
GPYNSSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGS
RAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGE
DAKAAARDIFSPKRSWKRQRYRLSTQTEGLQLLPGLIHVHRRKMFQATILSVENLQSSKS
TRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPTEPVAVEQLEK
GSPGGPPPSWVRDPRLPPCSLRQALTFFLDITSPSSPRLLRLLSTLAEEPSEQQELEALS
QDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSIYPGEIH
LTVAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGP
GTGIAPFRGFWQQRLHDIESKGLQPAPLTLVFGCRCSQLDHLYRDEVQDAQQRGVFGCVL
TAFSREPDSPKTYVQDILRTELASEVHRVLCLERGHMYVCGDVTMATSVLQTVQRILATE
GDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFD
LPGSDTPGP
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcccgggccaccctgtggcctggggctgggg
ctgggcctcgggctgtgcggcaagcagggcccagcctccccagcaccagagcccagccgg
gcgcccgcatccccacccccaacccctccagcgccagaccacagccccaaacctagctcc
aacagtcctccgctaactcggcccccggaggggccgaagttccctcgagtgaagaactgg
gaggtgggcagcatcacctacgacaccctcagtgcccaggcacagcaggacgggccttgc
acccaaagacgctgcctgggctcccttgtgtttccccggaaactgcagagccggcccacc
cagggcgctccaccccctgaacagctgctggttcaggccagggacttcatcaaccagtac
tacagctccatcaagaggagcggctcccaggcccatgagcaacggcttcaggaagtggag
gccgaggtggcagccacaggcacctaccagcttcgggaaaatgaactggtctttggggcc
aagcaggcctggcgcaacgctccccgctgtgtgggccggatccagtgggggaagctgcag
gtcttcgatgcccgggactgcaggtctgcacaggaaatgttcacctacatctgcaaccac
atcaagtatgccaccaaccggggcaaccttcgttcagccatcacagtgttcccccagcgc
ggcccgggccgcggagacttccggatctggaacagccagctggtgcgctatgcgggctac
agacagcaggacggctctgtgcggggggacccagccaacgtggagatcaccgagctctgc
atccagcacggctggaccccaggaaacgggcgcttcgatgtgctgcccctgctgcttcag
gtcccggacgagcccccagaactcttcactctgccccctgagttggtcctggaggtgtcc
ctggagcaccccacgctggagtggttcgcggccctgggtcttcgctggtatgccctcccg
gcagtgtccaacatgctgctggaaatcggggggctagagttccctgcagcccctttcagc
ggctggtacatgagcacggagatcggcacacggaacctgtgtgaccctcaccgctacaac
atcctggaggatgtggccgtctgcatggacttggatacccggacaacgtcgtccctgtgg
aaagacaaggcggcggtggagattaacttggctgtgctgcacagttaccagctcgccaaa
gtgaccattgtggatcaccacgctgccacagcgtccttcatgaagcacctggagaatgag
cagaaggccagagggggctgccctgctgactgggcctggatcgtgccccccatctcgggc
agcctcactcctgtcttccatcaagagatggtcaactatttcctgtcccctgccttccgc
taccagccagacccctggaaggggagtggagccaagggcactggcatcaccaggaagaag
acctttaaggaagtggccaatgcagtgaagatctctgcctcactcatgggcacagtgatg
gcaaagagagtgaaggccacaatcctgtacggctccgagactggccgggcccagagctac
gcgcagcagctggggaggctcttccggaaggcgttcgacccccgggttctgtgcatggac
gagtatgatgtggtgtccctcgaacacgagacgctggtgttggtggtgaccagcacattt
gggaatggagatccaccagagaacggagagagttttgcagcagccctgatggagatgtcc
ggcccctacaacagctctccgcggccagagcagcacaagagttacaaaatccgcttcaac
agcgtctcctgctcagacccgctggtgtcttcttggcggcggaagaggaaggagtccagt
aacacagacagtgcaggggctctaggcaccctcaggttctgtgtgttcggcctgggctcc
cgggcatacccccacttctgtgcctttgctcgtgcggtggacacgcggctggaagagctg
ggcggggagcggctgctgcagctgggccagggcgatgagctatgcggccaggaggaggcc
ttccgcggctgggcccaggctgccttccaggcctcctgtgagactttctgcgtgggagag
gatgccaaggctgctgcccgggacatatttagccccaaacggagctggaagcgccagagg
taccggctgagtacccagaccgagggcctacagttgctgccaggtctgatccacgtgcac
aggcggaagatgttccaggccacaatcctctcagtagaaaacctgcaaagcagcaaatcc
acccgggccacaatcctggtgcgtctggatactggtggccaggaagggctacagtaccag
ccaggggaccacataggagtctgcccacccaaccggcctggcctcgtggaggcgctgctg
agccgtgtggaggacccgccgccacccacggagcctgtggcagtggagcagctggagaaa
ggcagccctggtggccctccccccagctgggtgcgggacccccggctgcccccgtgctcg
ctgcgccaggctctcaccttcttcctggacatcacctctccatccagtcctcgactcctt
cgactgctcagcaccttggctgaagagcccagcgaacagcaggagttggaggccctcagc
caggacccccggcgctacgaggagtggaagtggttccgctgccccacgctgctggaggtg
ctggagcaattcccgtccgtggcactgcctgctcccctgctcctcacccagctgcccctg
ctgcagccccggtactactcagtcagctcggcacccagcatctacccaggagagatccac
ctgactgtcgctgtgctggcctacaggacccaggatgggctgggccccctgcactatgga
gtctgctccacgtggctgagccaactcaaggctggagaccccgtgccctgcttcatcagg
ggggctccctccttccggctgccacctgatcccagcttgccctgcatcctggtgggcccc
ggcaccggcatcgcccccttccgggggttctggcagcagcgcctgcatgacattgagagc
aaagggctgcagcccgcgcccctgactctggtgttcggctgccgatgctcccagctggat
cacctgtaccgcgacgaggtgcaggacgcccagcagcgcggagtgtttggctgcgtcctc
accgccttctccagggaacccgacagccccaagacctacgtgcaggacatcctgaggacc
gagctggcgtctgaggtgcaccgcgtgctgtgcctcgaacgcggccacatgtatgtctgc
ggagatgtcaccatggcaaccagcgtcctgcagacggtgcagcgaatcctggccaccgag
ggcgacatggagctggacgaggccggtgacgtcatcggcgtgctgcgggatcagcaacgc
taccacgaggacattttcgggctcacgctgcgcacccaggaggtgacaagccgcatacgc
acccagagtttctccttgcaggagcggcagctgcggggcgcggtgccctgggcgttcgac
ctacccggctccgacacccccggcccctga
DBGET
integrated database retrieval system
