| Entry |
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| Name |
(RefSeq) insulin-like growth factor 1 receptor isoform X3
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| KO |
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| Organism |
ocu Oryctolagus cuniculus (rabbit)
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| Pathway |
| ocu01521 | EGFR tyrosine kinase inhibitor resistance |
| ocu04213 | Longevity regulating pathway - multiple species |
| ocu04550 | Signaling pathways regulating pluripotency of stem cells |
| ocu04914 | Progesterone-mediated oocyte maturation |
| ocu05202 | Transcriptional misregulation in cancer |
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| Brite |
KEGG Orthology (KO) [BR:ocu00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100144342
04014 Ras signaling pathway
100144342
04015 Rap1 signaling pathway
100144342
04066 HIF-1 signaling pathway
100144342
04068 FoxO signaling pathway
100144342
04151 PI3K-Akt signaling pathway
100144342
04152 AMPK signaling pathway
100144342
04150 mTOR signaling pathway
100144342
09133 Signaling molecules and interaction
04081 Hormone signaling
100144342
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100144342
04140 Autophagy - animal
100144342
09143 Cell growth and death
04114 Oocyte meiosis
100144342
09144 Cellular community - eukaryotes
04510 Focal adhesion
100144342
04520 Adherens junction
100144342
04550 Signaling pathways regulating pluripotency of stem cells
100144342
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100144342
04914 Progesterone-mediated oocyte maturation
100144342
09156 Nervous system
04730 Long-term depression
100144342
09149 Aging
04211 Longevity regulating pathway
100144342
04213 Longevity regulating pathway - multiple species
100144342
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100144342
05202 Transcriptional misregulation in cancer
100144342
05205 Proteoglycans in cancer
100144342
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100144342
05214 Glioma
100144342
05218 Melanoma
100144342
05215 Prostate cancer
100144342
05224 Breast cancer
100144342
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100144342
01522 Endocrine resistance
100144342
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:ocu01001]
100144342
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:ocu04090]
100144342
Enzymes [BR:ocu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100144342
Protein kinases [BR:ocu01001]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100144342
CD molecules [BR:ocu04090]
Proteins
100144342
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:87283661..87540557
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| AA seq |
1366 aa
MKSGSGGGSRTSAWGLLFLSAALSVWPTSGEICGPGIDIRNDFQQLKRLENCTVIEGFLH
ILLISKAEDYRNYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
MCPGTLEEKPLCEKTAINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCH
APDDDTACVACRHYYFSGVCVPACPPNTYRFEGWRCVDRDFCANIPNADGGDSEGFVIHD
GECMQECPSGFIRNGSQSMFCIPCEGPCPKVCEEDKKTKTIDSVNSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKISHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEDVTGTKGRQSKGDINTR
NNGERASCESDILHFTSTNTWKNRIILTWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDLEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDILSASNSSSQLIVKWSPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKEDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDVAQVANTTLSGRGRNGTAVDMYNSTDLEELETEYPFFE
TRVDKEITVISNLRPFTSYRIDIHSCNHEAEKLGCSASNFVFARTKPAEGADDIPGPVTW
EARPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQQYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTEPVFFYVPAKATYESFMHLIIALPVAILLIVGGLLIVLYVFHR
KRSNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEVENRAPAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVV
LWEIATLAEQPYQGFSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLE
IIGSVRDEMEPGFREVSFYYSEENKPPEAEELDLEPENMESVPLDPSANAAAAVAALQPD
RHKAENGPSAGAMVLRASFDERRPYAHMNGGRTDERALPLPQSSTC |
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| NT seq |
4101 nt +upstreamnt +downstreamnt
atgaagtctggctccggaggagggtcccggacctcggcgtgggggctcctgtttctctcc
gccgcgctctcggtctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aatgacttccagcagctgaagcgcctggagaactgcacggtgatcgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgcaactaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctgttc
cccaacctcacggtcatccgcggctggaagctcttctacaactatgccctggtcattttc
gagatgactaacctcaaagacatagggctctataacctgaggaacatcacccggggggcc
atcaggatcgagaagaacgccgacctctgctacctctccacggtggactggtctctcatc
ctggacgccgtgtccaacaactacattgtggggaacaagtccccaaaggagtgcggggac
atgtgtccagggaccttggaggagaagccgttgtgcgagaagaccgccatcaacaacgag
tacaactaccgctgctggaccaccaaccgctgccagaaaatgtgccccagcgcgtgcggg
aagcgggcatgcaccgagaacaacgaatgctgccaccccgagtgcctgggcagctgccac
gcgcctgacgacgacacggcctgcgtcgcctgccgccactactatttctccggcgtctgc
gtgcccgcctgcccgcccaacacctaccgattcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccctaacgccgatggcggcgactccgagggctttgtcatccacgac
ggcgagtgcatgcaggagtgcccgtcgggcttcatccgcaacggcagccagagcatgttc
tgcattccctgtgaaggtccgtgccccaaggtctgtgaggaagacaagaaaacaaagacc
attgattctgttaattctgctcaaatgctccaaggctgcaccatcttcaaggggaatctg
ctcattaacatccgacgaggcaataacattgcctcggagctggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatcagccactcgcacgccttggtctccttgtcc
ttcctgaagaacctccgccagatcctaggggaggagcagctggaagggaactactccttc
tacgtcctggacaaccagaacttgcagcagctctgggactgggaccaccgcaacctgacc
atcaaagctgggaagatgtacttcgccttcaaccccaaactgtgcgtgtcggaaatttac
cgcatggaggacgtgacggggacgaaaggacgccagagcaagggcgacataaacaccagg
aacaacggggagagagcctcctgtgagagcgacatcctgcatttcacctccaccaacacg
tggaagaaccgcatcatcctaacctggcaccgctaccgcccccctgactacagggatctc
atcagcttcaccgtctactacaaggaggcaccctttaaaaatgtgacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctccctcccaacaag
gacctagagcctggtattctactgcaagggctgaagccctggactcagtacgccgtctac
gtcaaggccgtgaccctcaccatggtggagaatgaccacatccgaggggccaagagtgaa
atcttgtacattcgcaccaacgcctcagttccttccatccccttggacatcctctcggca
tccaactcctcgtctcagctgatcgtgaagtggagccccccgtccctgcccaacgggaac
ctgagctactacatcgtgaggtggcagcggcagccccaggacggctacctgtaccggcac
aactactgctccaaagaagacaaaattcccatcaggaagtatgcggacggcaccatcgac
gtggaggaggtgacggagaaccccaagacggaggtctgtggcggagagaaggggccttgc
tgcgcgtgccccaagaccgaagccgagaagcaggctgagaaggaggaggcggagtaccgc
aaggtgttcgagaacttcctgcacaactccatcttcgtgcccagacccgagaggaagcgg
agagatgtcgcccaggtggccaacaccacgctgtccggccgaggcaggaacggcacggcg
gtggacatgtacaacagcacggacctggaggagctggagacagaataccctttctttgag
accagagtggacaaggagataacggtcatatctaacctgcggccgtttacttcctaccgc
atcgatatccacagctgcaaccacgaggcggagaagctggggtgcagtgcctccaacttt
gtctttgcgagaaccaagcctgcagaaggagcggatgacattccgggccctgtgacctgg
gaagcaaggcctgaaaactccatctttctgaagtggccggaacctgagaaccccaacgga
ttgatcctaatgtatgagataaaatacgggtctcagatcgaggaccagagggaatgtgtg
tccagacagcagtaccgaaagtatggaggagccaagctcaaccggctaaacccggggaac
tatacagcccggattcaggctacgtcgctctccgggaacgggtcgtggacggagcctgtg
ttcttctatgtcccagccaaagccacctacgagagcttcatgcacctgatcatcgcgctg
ccggtcgccatcctgctcatcgtgggagggctgctgatcgtgctgtacgtcttccacagg
aagagaagtaacagcagactggggaacggagtgctgtacgcctctgtgaacccggagtac
ttcagtgcagccgacgtatacgtccctgacgagtgggaggtggcgcgggagaagatcacc
atgagccgcgagcttggccagggctccttcgggatggtctacgaaggcgtcgccaagggc
gtggtaaaggatgagccggaaaccagggtggccatcaagacggtgaacgaggccgccagc
atgcgggagaggatcgagtttctcaacgaggcgtctgtgatgaaggagttcaattgtcac
cacgtggtgcggttgctgggggtggtgtcccagggccagcccaccctggtcatcatggag
ctgatgacgcgaggggacctcaagagctatctcaggtccctgcgaccggaagtggagaat
cgggccccagcccctccgagtctgagtaagatgatccaaatggccggggagattgcagat
ggcatggcatacctcaacgccaacaagttcgtgcacagagaccttgctgcccggaactgc
atggtggccgaggatttcacagtcaagatcggagatttcggaatgacgcgggacatctac
gagacggactactaccggaaaggggggaaaggcttgctgcccgtgcgctggatgtccccc
gagtccctcaaagatggagtcttcaccacccactctgacgtctggtccttcggagtcgtc
ctctgggagatcgccacgctggcagagcagccgtaccagggattctccaacgagcaggtc
ctgcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatgctg
tttgagctgatgcgcatgtgttggcaatacaaccccaagatgcggccttccttcctggag
atcatcggcagtgtcagagacgagatggagcccggcttccgcgaggtctccttctactac
agcgaggagaacaagccgcccgaggccgaggagctcgacctggagcccgagaacatggag
agcgtgcccctggacccctccgcgaacgccgctgccgccgtcgccgccctgcagcccgac
aggcacaaggccgagaacggcccgagtgcaggggcgatggtcctgcgagccagctttgac
gagaggcgaccctacgcgcacatgaatgggggccgcacagacgagcgggccctgccgctg
ccgcagtcttcgacctgctga |
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