Oryctolagus cuniculus (rabbit): 100328559
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Entry
100328559 CDS
T03373
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00020
Citrate cycle (TCA cycle)
ocu00480
Glutathione metabolism
ocu01100
Metabolic pathways
ocu01200
Carbon metabolism
ocu01210
2-Oxocarboxylic acid metabolism
ocu01230
Biosynthesis of amino acids
ocu04146
Peroxisome
ocu05230
Central carbon metabolism in cancer
Module
ocu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ocu_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100328559 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100328559 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100328559 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100328559 (IDH1)
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100328559 (IDH1)
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GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
100328559
NCBI-ProteinID:
XP_002712664
Ensembl:
ENSOCUG00000002671
UniProt:
A0A5F9CXT8
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Position
7:24474193..24494225
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AA seq
414 aa
AA seq
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MSKKIHGGSVVEMQGDEMTRIIWELIKEKLIYPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYHVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG
KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFANALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLSQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatccatggcggttctgtggttgagatgcaaggagatgaaatgacaaga
attatttgggaattgattaaagagaaacttatatatccgtatgtggaattggatctgcat
agctatgacttaggcatagagaaccgggatgccaccaatgaccaagtcaccaaggatgca
gcagaagctataaagaagtaccacgtgggcgtcaagtgtgctaccatcaccccggatgag
aagagagttgaggagttcaagttgaaacaaatgtggaaatcgcctaatggcaccatccga
aatattctgggtggcactgtcttcagagaagctattatctgcaaaaatatcccccggctt
gtgactgggtgggtaaaacccatcatcataggccgccatgcttatggagatcaatacaga
gcaactgattttgttgtccccgggcctgggaaagtagagataacctacacgccaagtgat
gggacccagaaggtgacatacctggtgcataactttgaagagggtggtggcgttgccatg
gggatgtacaatcaagataaatcgattgaagattttgcacacagttccttccagatggct
ctgtctaagggctggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgtttcaaagacatctttcaggagatttatgacaagcagtacaaatcccagtttgaa
gcccaaaagatctggtatgagcacaggctcatcgacgacatggtggcccaagcaatgaaa
tcagaaggaggcttcatctgggcctgtaaaaattatgatggagatgtgcagtcagactcc
gtggcccaagggtatggctctctcggcatgatgaccagtgtgctgatttgtccagatggc
aagacagtggaagcagaggctgcccacgggactgtaacgcgtcactaccgcatgcaccag
aaaggacaggagacatccacaaatcccattgcttccatttttgcctggaccagagggcta
gcccacagagcaaagcttgataacaataaagagctcagcttcttcgcaaacgctttggaa
gaagtctgtattgagactattgaggctggcttcatgaccaaggacttggctgcttgcatt
aaaggtttacccaatgtgcaacgctctgactacttgaatacatttgagttcatggacaaa
cttggagaaaacttgaagataaaactatctcaggccaaactttaa
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