Oryctolagus cuniculus (rabbit): 100340245
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Entry
100340245 CDS
T03373
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X2
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00230
Purine metabolism
ocu01100
Metabolic pathways
ocu04024
cAMP signaling pathway
ocu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100340245
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100340245
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100340245
Enzymes [BR:
ocu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100340245
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
100340245
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD
SpoVT_C
PEX15_N
DUF7334
Motif
Other DBs
NCBI-GeneID:
100340245
NCBI-ProteinID:
XP_002715028
Ensembl:
ENSOCUG00000009218
UniProt:
A0A5F9CBU0
LinkDB
All DBs
Position
12:830941..1466200
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AA seq
1062 aa
AA seq
DB search
MASPEELAAPRPQAPLPAAGDEPGSGSGKLRPEPRRSAAGGGSAAGPGPAPERPGRGRAE
RAAPPRPPPAPAGRAGPAGGPGALSALGGCWVAARAPFALALSSPVPSSSPSSSYFWPPP
PLPPPSFLPSASAFRLPVRLPGREGAAAGGGGGGDAGGGGQEARAPLSVPASSSPRGGGG
RRRLFLSPALHGLLLPARAGPRPRPPPPRLPFGAAVRRAGFPGFPGAGGGCSGPGPGSGP
GPGPGPGGGGRTPRRPGGAGFALASLLFGPDMEDGPSNNASCFRRLTECFLSPSLTDEKV
KAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESTPKEVSRYQDTNMQGVVYELN
SYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGLKEGRPRL
VPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGD
LIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKT
YFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKT
KEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVI
GVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHS
ICTAEEWQGLMRFTLPSRLCKEVELFHFDIGPFENMWPGIFVYMIHRSCGTSCFELEKLC
RFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNSYGLFTDLERKGLLIACLCHDLDHRG
FSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKA
IIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTA
NDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTE
PLLKACRDNLSQWEKVIRGEETALWISSPATAPDPCPGKTED
NT seq
3189 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccggaggagctcgccgctccccgcccccaggcgcccctgccagcggccggg
gacgagccgggctccggctccggcaaactccgcccggagccccggcgcagcgcggccggc
ggggggagcgcggcgggcccgggcccggcccccgagcggccaggccgcggccgggccgag
cgcgccgcgcccccgcgcccgccccccgcccccgcaggccgcgccggccccgctgggggc
cccggcgcgctctctgcgctcggcggctgctgggtggctgcccgcgctcccttcgcgctc
gccctctcctcccccgtcccctcctcctctccatcttcctcttacttctggccgccgccc
cccctgccccctccctcatttctcccctccgcgtctgcctttcgcctccccgtgcgtctc
ccagggagggagggcgcggcggcgggaggcggcggcggcggcgatgctggcggcggcgga
caggaggcgagagctccgctgagcgtccccgccagcagcagtccccgcggcggcggcggg
cggcggcggctcttcctctcgcctgcgctccacggcttgctgctcccagcccgcgccggg
ccgcggccgcggccgccgccgccccggcttccctttggcgcggccgtccgccgcgcgggc
ttccccggcttcccgggcgctggcgggggctgctccggccccggccccggctccggcccc
ggccccggccccggccccggcggcggcggccgaactccacggcggcccggaggcgccggc
tttgcgctcgcctcgctgctcttcggccccgacatggaagatggaccttctaataatgcg
agctgcttccgaaggctgaccgagtgtttcctcagccccagtttgacagatgaaaaagtg
aaggcgtatctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagt
gcagagactgtagaaaaatggctgaagaggaagaacaacaaaccagaagatgaatcgact
cctaaggaagtcagcaggtaccaagatactaacatgcaaggggttgtgtatgaactgaac
agctacatagaacaacggctggacacggggggagataaccagctgctactctacgagttg
agcagcatcattaagatagccacgaaagctgatgggtttgcactgtatttccttggagag
tgcaataatagcctgtgtgtgttcaccccgccgggcttaaaggaaggcaggccccgcctc
gtccctgccgggcccatcacccagggtacgaccatctctgcctacgtggccaagtccagg
aagacgctgctagtggaagacatccttggggatgaacgatttccaagaggcactgggctg
gagtcagggactcgtatccagtctgttctttgcttgcccatcgtcactgccattggtgat
ttgattggcatccttgagctgtatcggcactggggcaaagaagccttctgcctcagtcac
caggaggttgcaacagcaaatcttgcctgggcttcggtagcaatacatcaggtgcaggtg
tgcagaggccttgccaaacagactgaattgaatgactttctactcgacgtatcaaaaaca
tattttgataacatagtcgcaatagattctctacttgaacacataatgatatatgcaaaa
aacctggtgaatgccgatcgttgcgcacttttccaggtagaccataagaacaaggagtta
tattcagacctttttgatattggagaggagaaggaaggaaagcctgtcttcaagaagacc
aaagagatcagattttcaattgagaagggaattgctggtcaagtagcaagaaccggggaa
gtcctgaacattccggatgcctatgcagatccacgcttcaacagagaagtggacttgtac
acaggctacaccactcggaacatcctgtgtatgcccatcgtgagccgcgggagcgtgata
ggcgtggtgcagatggtgaacaaaatcagcggcagtgccttctcaaagacggatgagaac
aacttcaaaatgtttgctgtcttctgcgctctcgccttacactgtgctaatatgtaccac
aggatccgtcactcggagtgcatttaccgggtcaccatggagaagctgtcctaccacagc
atctgcacagcagaggagtggcaaggcctcatgcgcttcaccctgccctcgcggctctgc
aaggaggttgagctgttccactttgacattggtccttttgagaacatgtggcctggaatt
tttgtctatatgatccatcggtcctgtgggacatcctgctttgagcttgaaaagctgtgc
cgttttatcatgtctgtgaagaagaactaccggcgcgttccttaccacaactggaagcac
gcggtgaccgtggcacactgcatgtatgccatactgcagaacagctacgggctgttcaca
gacctggagcgcaaaggactgctgattgcgtgcctgtgtcatgacctggaccaccggggc
ttcagtaacagctacctgcagaagtttgaccaccccctggcggcactgtactccacctcc
acgatggagcagcaccacttctcccagacggtgtccatcctccagttggaagggcacaac
atcttctccaccctgagctccagtgagtatgaacaggtgcttgagatcatccgcaaagcc
atcattgccacagaccttgctttgtactttggaaacaggaagcagctggaagagatgtac
cagactggatcgctaaaccttaataaccaatcacatagagaccgggtaattggtttgatg
atgactgcctgcgacctttgttctgtgacaaaactgtggccggttacaaagttgacagca
aatgatatatatgcagaattctgggctgagggtgatgaaatgaagaagctgggaatacaa
cccattcctatgatggacagagacaagcgggacgaagtccctcaaggccagcttggattc
tacaatgctgtagccattccctgttacaccaccctcacccaaatcctgcctcccaccgag
cctctgcttaaggcatgcagggataacctcagtcagtgggagaaggtgatccgaggagag
gagacggcgctgtggatctcatcaccagccacggcccccgacccctgtcctgggaagacg
gaggactga
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