KEGG   Oryctolagus cuniculus (rabbit): 100341599
Entry
100341599         CDS       T03373                                 
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01521  EGFR tyrosine kinase inhibitor resistance
ocu01522  Endocrine resistance
ocu04012  ErbB signaling pathway
ocu04015  Rap1 signaling pathway
ocu04062  Chemokine signaling pathway
ocu04081  Hormone signaling
ocu04137  Mitophagy - animal
ocu04144  Endocytosis
ocu04360  Axon guidance
ocu04370  VEGF signaling pathway
ocu04510  Focal adhesion
ocu04520  Adherens junction
ocu04530  Tight junction
ocu04540  Gap junction
ocu04611  Platelet activation
ocu04613  Neutrophil extracellular trap formation
ocu04625  C-type lectin receptor signaling pathway
ocu04727  GABAergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04810  Regulation of actin cytoskeleton
ocu04912  GnRH signaling pathway
ocu04915  Estrogen signaling pathway
ocu04917  Prolactin signaling pathway
ocu04919  Thyroid hormone signaling pathway
ocu04921  Oxytocin signaling pathway
ocu04926  Relaxin signaling pathway
ocu05100  Bacterial invasion of epithelial cells
ocu05135  Yersinia infection
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05163  Human cytomegalovirus infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05168  Herpes simplex virus 1 infection
ocu05203  Viral carcinogenesis
ocu05205  Proteoglycans in cancer
ocu05207  Chemical carcinogenesis - receptor activation
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05219  Bladder cancer
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100341599
   04015 Rap1 signaling pathway
    100341599
   04370 VEGF signaling pathway
    100341599
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100341599
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100341599
   04137 Mitophagy - animal
    100341599
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100341599
   04520 Adherens junction
    100341599
   04530 Tight junction
    100341599
   04540 Gap junction
    100341599
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100341599
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100341599
   04613 Neutrophil extracellular trap formation
    100341599
   04625 C-type lectin receptor signaling pathway
    100341599
   04062 Chemokine signaling pathway
    100341599
  09152 Endocrine system
   04912 GnRH signaling pathway
    100341599
   04915 Estrogen signaling pathway
    100341599
   04917 Prolactin signaling pathway
    100341599
   04921 Oxytocin signaling pathway
    100341599
   04926 Relaxin signaling pathway
    100341599
   04919 Thyroid hormone signaling pathway
    100341599
  09156 Nervous system
   04727 GABAergic synapse
    100341599
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100341599
  09158 Development and regeneration
   04360 Axon guidance
    100341599
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100341599
   05207 Chemical carcinogenesis - receptor activation
    100341599
   05208 Chemical carcinogenesis - reactive oxygen species
    100341599
   05203 Viral carcinogenesis
    100341599
  09162 Cancer: specific types
   05219 Bladder cancer
    100341599
  09172 Infectious disease: viral
   05161 Hepatitis B
    100341599
   05168 Herpes simplex virus 1 infection
    100341599
   05163 Human cytomegalovirus infection
    100341599
   05167 Kaposi sarcoma-associated herpesvirus infection
    100341599
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100341599
   05152 Tuberculosis
    100341599
   05100 Bacterial invasion of epithelial cells
    100341599
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100341599
   05418 Fluid shear stress and atherosclerosis
    100341599
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100341599
   01522 Endocrine resistance
    100341599
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100341599
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocu04131]
    100341599
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100341599
Protein kinases [BR:ocu01001]
 Non-receptor tyrosine kinases
  SRC family
   100341599
Membrane trafficking [BR:ocu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100341599
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    100341599
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100341599
  Macropinocytosis
   Kinases
    100341599
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 100341599
NCBI-ProteinID: XP_051701024
Ensembl: ENSOCUG00000009585
LinkDB
Position
4:complement(10460132..10505905)
AA seq 542 aa
MGSSKSKPRDASQRRRSLEPAESAHGGAGGAFPSTQTPNKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcagcaagagcaagcccagggacgcgagccagcggcgccgcagcctggagccg
gccgagagcgcccacggaggggccggcggcgccttccccagcacgcagacccccaacaag
ccggcctccgccgacggccaccgcggccccagcgccgccttcgcccctgctgccgccgag
cccaaactcttcgggggcttcaactcttcggacaccgtcacctccccgcagagggccggg
ccgctggctggcggggtgaccaccttcgtggccctctacgactatgagtcccggacggag
accgacctgtccttcaagaagggggagcggctgcagatcgtcaacaacacgaggaaggtg
gatgtcagggagggagactggtggctggcccactcgctcagcacgggacagaccggctac
atccccagcaactacgtggcgccctccgactccatccaggccgaggagtggtacttcggc
aagattaccaggcgggagtcggagcggttactgctcaatgcagaaaacccaagggggacc
ttcctggtgcgcgagagtgagaccacgaaaggtgcctactgcctgtcagtgtcggacttc
gacaacgccaagggcctcaacgtgaagcactacaagatccgcaagctggacagcggcggc
ttctacatcacctcccgcacgcagttcagcagcctgcagcagctcgtggcctactactcc
aagcacgccgacggcctgtgccaccgcctcaccaccgtgtgccccacgtccaagccgcag
actcagggcctggccaaggacgcctgggagatcccccgcgagtcgctgcggctggaggtc
aaactgggccagggctgcttcggcgaggtgtggatggggacctggaacggcaccaccagg
gtggccatcaaaaccctgaagcccggcaccatgtccccggaggccttcctgcaggaggca
caggtcatgaagaagctgcggcacgagaagctggtgcagctgtacgccgtggtgtccgag
gagcccatctacatcgtcacagagtacatgagcaaggggagcttgctggacttcctcaag
ggagagacgggcaagtacctccggctgccgcagctggtggacatggctgcgcagatcgcc
tcaggcatggcgtacgtggagcggatgaactacgtgcaccgggacctccgagccgccaac
atcctggtgggggagaacctggtgtgcaaggtggctgacttcgggctggcccggctcatc
gaagacaacgagtacacggcccggcaaggtgccaagttccccatcaagtggacagctccg
gaggctgcactctatggccggttcaccatcaagtcagacgtgtggtcctttggcatcctg
ctgacggagctcaccacaaagggacgggtgccctaccccgggatggtgaaccgcgaggtg
ctggaccaggtggagcggggctaccggatgccctgcccgcccgagtgccccgagtccctg
catgacctcatgtgccagtgctggcggaaggagccggaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactacttcacgtccaccgagccccagtaccagcctggagag
aacctatag

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