KEGG   Oryctolagus cuniculus (rabbit): 100343958
Entry
100343958         CDS       T03373                                 
Name
(RefSeq) adenylate cyclase type 3 isoform X1
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00230  Purine metabolism
ocu01100  Metabolic pathways
ocu01522  Endocrine resistance
ocu04015  Rap1 signaling pathway
ocu04020  Calcium signaling pathway
ocu04022  cGMP-PKG signaling pathway
ocu04024  cAMP signaling pathway
ocu04062  Chemokine signaling pathway
ocu04072  Phospholipase D signaling pathway
ocu04081  Hormone signaling
ocu04082  Neuroactive ligand signaling
ocu04114  Oocyte meiosis
ocu04211  Longevity regulating pathway
ocu04213  Longevity regulating pathway - multiple species
ocu04261  Adrenergic signaling in cardiomyocytes
ocu04270  Vascular smooth muscle contraction
ocu04371  Apelin signaling pathway
ocu04540  Gap junction
ocu04611  Platelet activation
ocu04713  Circadian entrainment
ocu04714  Thermogenesis
ocu04723  Retrograde endocannabinoid signaling
ocu04724  Glutamatergic synapse
ocu04725  Cholinergic synapse
ocu04727  GABAergic synapse
ocu04740  Olfactory transduction
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04911  Insulin secretion
ocu04912  GnRH signaling pathway
ocu04913  Ovarian steroidogenesis
ocu04914  Progesterone-mediated oocyte maturation
ocu04915  Estrogen signaling pathway
ocu04916  Melanogenesis
ocu04918  Thyroid hormone synthesis
ocu04921  Oxytocin signaling pathway
ocu04923  Regulation of lipolysis in adipocytes
ocu04925  Aldosterone synthesis and secretion
ocu04926  Relaxin signaling pathway
ocu04927  Cortisol synthesis and secretion
ocu04928  Parathyroid hormone synthesis, secretion and action
ocu04934  Cushing syndrome
ocu04935  Growth hormone synthesis, secretion and action
ocu04962  Vasopressin-regulated water reabsorption
ocu04970  Salivary secretion
ocu04971  Gastric acid secretion
ocu04972  Pancreatic secretion
ocu04976  Bile secretion
ocu05032  Morphine addiction
ocu05163  Human cytomegalovirus infection
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05207  Chemical carcinogenesis - receptor activation
ocu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100343958
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100343958
   04371 Apelin signaling pathway
    100343958
   04020 Calcium signaling pathway
    100343958
   04072 Phospholipase D signaling pathway
    100343958
   04024 cAMP signaling pathway
    100343958
   04022 cGMP-PKG signaling pathway
    100343958
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100343958
   04081 Hormone signaling
    100343958
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100343958
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100343958
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100343958
   04062 Chemokine signaling pathway
    100343958
  09152 Endocrine system
   04911 Insulin secretion
    100343958
   04923 Regulation of lipolysis in adipocytes
    100343958
   04912 GnRH signaling pathway
    100343958
   04913 Ovarian steroidogenesis
    100343958
   04915 Estrogen signaling pathway
    100343958
   04914 Progesterone-mediated oocyte maturation
    100343958
   04921 Oxytocin signaling pathway
    100343958
   04926 Relaxin signaling pathway
    100343958
   04935 Growth hormone synthesis, secretion and action
    100343958
   04918 Thyroid hormone synthesis
    100343958
   04928 Parathyroid hormone synthesis, secretion and action
    100343958
   04916 Melanogenesis
    100343958
   04925 Aldosterone synthesis and secretion
    100343958
   04927 Cortisol synthesis and secretion
    100343958
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100343958
   04270 Vascular smooth muscle contraction
    100343958
  09154 Digestive system
   04970 Salivary secretion
    100343958
   04971 Gastric acid secretion
    100343958
   04972 Pancreatic secretion
    100343958
   04976 Bile secretion
    100343958
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100343958
  09156 Nervous system
   04724 Glutamatergic synapse
    100343958
   04727 GABAergic synapse
    100343958
   04725 Cholinergic synapse
    100343958
   04723 Retrograde endocannabinoid signaling
    100343958
  09157 Sensory system
   04740 Olfactory transduction
    100343958
   04750 Inflammatory mediator regulation of TRP channels
    100343958
  09149 Aging
   04211 Longevity regulating pathway
    100343958
   04213 Longevity regulating pathway - multiple species
    100343958
  09159 Environmental adaptation
   04713 Circadian entrainment
    100343958
   04714 Thermogenesis
    100343958
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100343958
   05207 Chemical carcinogenesis - receptor activation
    100343958
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100343958
   05163 Human cytomegalovirus infection
    100343958
  09165 Substance dependence
   05032 Morphine addiction
    100343958
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100343958
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100343958
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100343958
Enzymes [BR:ocu01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100343958
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA Peptidase_S49_N
Other DBs
NCBI-GeneID: 100343958
NCBI-ProteinID: XP_051699163
Ensembl: ENSOCUG00000015443
LinkDB
Position
2:complement(174169933..174246041)
AA seq 1214 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDADRGVGRTHEISVRNSGACLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVGFAALFDCYVVVMCAVVFSSDKLAPLVVAGIGLLLDLV
LFVVCKKGLLPDRLTRKAVPYLLWLLITAQIFSYLGLNFAQAHAASDTVGWQAFFLFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELQGMQLLREILANIFLYLCVIIVG
VMSYYMADRKQRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGGSRCD
YLEEKGIETYLIIASQPAVKAAAQNGLHGSALPNGAPASSKPSSPALIETKEPVGGSQAG
SSTWEEPEQQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQ
VVKKRNTFLLSMRFMDPDLESRYSEEKEKQSGAAFSCSCVVLLCTALVQILIDPWLMTNY
VTFVVGEVLLLILTVCSLAAIFPRAFPKKLVAFSTWIDQTRWARNTWAMLAIFILVMANV
VDMLSCLQDYAGPGNGTAGQELGGGCLENPKYYSYVAVLSLVATIMLVQVSHMVKLTLML
LVTGAVAAINLTAWSPVFDEYDHRRFQEHGFPLVALEKMQVVSAPGLNGTDSRLPLMPSK
YSMTAMMLVMMLSFYYFSRHVEKLARTLFLWKMEVHDQKERVNEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVHQRVWGVLGAASRGRRCLGHLQFWARAAREPAGTGQGPERHGGQRSHAPGRAPG
LAWPRLHPDPCSPQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAYPN
GSSVTLPHQVVDNP
NT seq 3645 nt   +upstreamnt  +downstreamnt
atgcccaggaaccagggcttctcggagcccgagtactcggccgagtactccgccgagtac
tcggtcagcctgccgtcggatgcggaccgcggcgtgggccggacgcacgagatctccgtg
cggaactcgggcgcctgcctgtgtctgccccgcttcatgcggctgaccttcgtgccggag
tccttggagaacctctaccagacctacttcaagcggcagcgccacgagaccctgctggtg
ctggtgggcttcgcggccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc
tcgagcgacaagctggcgccgctcgtcgtggctggcatcgggctgctgttggacctcgtg
ctcttcgtggtctgcaagaaggggctgctgcccgaccggctcacccggaaggcggtgccc
tacctgctgtggctgctgataacagcccagatcttctcctacctgggcctgaacttcgcg
caggcccacgcggccagcgacacggtgggctggcaggccttcttcctcttctccttcttc
atcacgctgccactcagcctcagccccatcgtcatcatctctgtggtctcctgtgtggtg
cacacgctcgtcctgggggtcactgtggcccagcagcagcaggacgagctgcaggggatg
cagctgctcagggagatcctggccaacatcttcctctacctgtgcgtcatcatcgtgggc
gtcatgtcctactacatggccgaccgcaagcagcgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctcatgctg
tccatcctgcccaagcacgtggccgatgagatgttgaaggacatgaagaaggatgagagc
cagaaagaccagcagcagttcaacaccatgtacatgtaccgccacgagaatgtcagcatc
ctcttcgccgacatcgtgggcttcactcagctctcctctgcctgcagcgcccaggagctc
gtgaagctgctcaacgagctctttgcgcgcttcgacaagctggcggccaaataccaccag
ctgcggatcaagatcctgggcgactgctactactgcatctgcgggctgcccgactaccgg
gaggaccacgccgtgtgctccatcctcatggggctcgccatggtggaggccatctcgtat
gtgcgggagaagacgaagactggcgtggacatgcgtgtgggggtgcacacaggcactgta
ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtccaccgacgtcacc
gtggccaacaagatggaggccggcggcatccccgggcgcgtgcacatctcccagagcacc
ctggactgcctgaagggagagttcgacgtggagcccggcgaggggggcagccgctgcgac
tacctggaggagaagggcatcgagacctacctcatcatcgcctcccagcccgccgtgaag
gccgccgcccagaacggcctccacggctcggccctgcccaacggagcgccagcttcctcc
aagcccagctcgcctgccctcattgagaccaaggagcccgtggggggcagccaggccggc
agttccacgtgggaggagcccgagcagcaggaggcgcaggcggacaacccctccttcccc
aaccctcgccggaggctgcgcctgcaggacctggccgaccgcgtggtggacgcctccgag
gacgagcacgagctcaaccagctgctcaacgaggccctgctggagcgcgagtccgcccag
gtggtgaagaagaggaacaccttcctcctgtccatgcggttcatggaccccgacctggag
tcccgctactcggaggagaaggagaagcagagcggggccgccttcagctgctcctgcgtc
gtcctgctgtgcacggccctggtgcagatcctcatcgacccctggctgatgacaaactac
gtgacctttgtggtcggggaggtcctgctcctgatcctgaccgtctgctcgctggctgcc
atctttccccgggcctttcctaagaagctggtagccttctccacgtggatcgaccagacc
cgctgggccaggaacacctgggccatgctggccatcttcatcctggtgatggcaaatgtc
gtggacatgctcagctgtctgcaggactacgcgggaccgggcaatggcacggcggggcag
gagctggggggcggctgcctggagaaccccaagtattacagctacgtggccgtgctgtcg
ctcgtcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatgctg
ctcgtcacgggcgccgtggccgccatcaacctcaccgcctggagccccgtcttcgacgag
tacgaccacaggcgcttccaggagcacggcttccccctggtggccctggagaagatgcag
gtcgtttccgcccctgggctcaacggtaccgacagcaggctgccgctgatgccatccaag
tactcgatgacagcgatgatgctggtcatgatgctgagcttttactacttctcgcgccac
gtggaaaagctggcacggaccctgttcctgtggaagatggaggtccacgatcagaaggag
cgtgtcaatgagatgcggcgctggaacgaggccttggtcaccaacatgctgcctgagcac
gtggcacgccatttcctggggtccaagaagagagacgaggagctgtacagccagtcctat
gatgagatcggagtcatgttcgcctccctgcccaacttcgccgacttctacaccgaggag
agcatcaacaatgggggcatcgagtgcctgcgcttcctcaacgagatcatctccgacttt
gactctctcctggacaatcccaaatttcgggtcatcacgaagatcaaaaccattggcagc
acctatatggcggcttcgggagtcaccccagatgtcaacaccaacggctttaccagctcc
aacaaggaagagaagtcagacaaggagcgctggcagcacctggccgacctggccgacttc
gcactcgccatgaaggacacgctgaccaacatcaacaatcagtccttcaacaacttcatg
ctgcgcataggcatgaacaaaggaggggttctggctggcgtcatcggagcccggaaacca
cactatgacatctggggcaacactgtcaatgtggccagcagaatggagtccacaggggtc
atgggcaacattcaggtacatcagcgagtgtggggtgtgctgggggcggcctccagaggg
agaagatgccttggccatctgcagttctgggcaagggcagcccgtgagcctgctgggact
gggcaagggccagaaaggcatggaggccagcgcagccatgctccggggagagcaccaggc
ctggcgtggcctaggctccaccctgacccctgctctccacaggtggtggaggaaacgcaa
gtgatcctgagagagtacggcttccgcttcgtgaggcgcggccccatctttgtgaaagga
aagggggaactgctgaccttcttcctgaaggggcgggacaagcccgctgcctaccccaac
ggctcctcggtgaccctgccccaccaggtggtcgacaacccctga

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