Oryctolagus cuniculus (rabbit): 100344504
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Entry
100344504 CDS
T03373
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00562
Inositol phosphate metabolism
ocu01100
Metabolic pathways
ocu04014
Ras signaling pathway
ocu04015
Rap1 signaling pathway
ocu04020
Calcium signaling pathway
ocu04024
cAMP signaling pathway
ocu04070
Phosphatidylinositol signaling system
ocu04919
Thyroid hormone signaling pathway
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu05205
Proteoglycans in cancer
Module
ocu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100344504
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100344504
04015 Rap1 signaling pathway
100344504
04020 Calcium signaling pathway
100344504
04070 Phosphatidylinositol signaling system
100344504
04024 cAMP signaling pathway
100344504
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100344504
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100344504
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100344504
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ocu04131
]
100344504
Enzymes [BR:
ocu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100344504
Membrane trafficking [BR:
ocu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100344504
Endocytosis
Macropinocytosis
Phospholipase C
100344504
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
100344504
NCBI-ProteinID:
XP_051679373
Ensembl:
ENSOCUG00000001816
LinkDB
All DBs
Position
18:38605306..38949813
Genome browser
AA seq
2314 aa
AA seq
DB search
MTSEEMAASVTPATQRKVVSALSTAEESKEKASGIGVPKVCTGRQSRQLPHSISQLNTFK
EDCSRSHLPEVISIAREKIVSDENSNERCWEQSVPESMKNLNISCSSLLRNHQHGLPPSQ
FYETCDSVTEQDLCLETGIPSPLERKVFPGIQLEIAGPPMDISPLGNHPAVMETDGSHPG
SNVALLHFHYEVDRRTSDTFCTMAENLTLDDCGNCVPLPPVEGEQKKNYMAYTSQLAGLA
QSCDNQNGQLPCGHCDTLNEKYLCFEGTCQKVDGVCSSDSFDKEDFTASPPAKTFLSQFE
HFPDNCEEVEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGRVAWS
YVDQKRNALLVSRGRVTEPLSSLEMRQGGSHHLSEAPWYLIYHAVRREETENPVGSLLRF
FTKLPASETAHGRVSLGPCLKQCVRDTVCEYRATLQRTSISQYVTGSLLEATTSLGTRSG
LLSTFGGSAGRMMLKERQPGTSMASSNALPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRKVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTSQNGERNALEDLVMRFN
EVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MEQSDMDTMRSLKDAMALHESSREYRKAVTRALHIPGCRVVPFCGVFLKELCEVLDGASG
LMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSLE
TEEEDSPSEGGGSRKNSLKDKARWQFIIGDLLDSENDIFEQPKDCDSHGSEESQKAFDHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPA
STKAKLGMLSNTTEPGKFPLLGNAGLNGLAEGVLDLFSVKAVYMGHPGIDIHTVCVQNKL
SSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKNAEKPNVQRNNTLGIS
TTKKKKKMLMRGESGDATDDEMVTRKGKMYKECRSRSGSDPQDINEQEEPEANAISSPPN
PLPSRRAHSLTTAASPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKG
FQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTIEE
NTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIF
GVGILQLNDFLVNCQGEHCTYDDILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFAS
KNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWD
GDDGMPIIYHGHTLTTKIPFKEVVEAIDRNAFITSDLPIIISIENHCSLPQQRKMAEIFK
TVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASM
QAQAYNGGNGNPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNGQEDNILEDRPEN
KSCNDKLQFEYSEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDL
VIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSFCEGI
RQNWEETPSALNPATSLSALIRTPRCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTY
PAATRIDSSNPSPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDK
SCPMYQKFSPLERDLDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRT
KPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQL
RNLHNEVLEISSLFINSRRMEENPSGSALPASLMFNTEERKCLQTHRVTVHGVPGPEPFV
VFTINGGTKAKQLLQQILKMDHDTKPVATDYFLMEEKYFISKEKNECRKQPFQRAIGPEE
EILQILSSWFPEEGYVGRIVFKTQQEIPEEKTIVQDDREVILSSEEESFFVQVHDVSPEQ
PRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTGTKKSSTPKPS
QRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASELKKFTKSTKQPRG
LTSPSQLLASENIQNKEEKPMCGLSPGDTMDYRQ
NT seq
6945 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaggaaatggcagcttctgttactcctgcgactcagagaaaagtagtgtct
gctctgtcaacagcagaggaaagtaaggaaaaggcctccggcatcggcgttccaaaggtg
tgtaccgggaggcagagcaggcagttgcctcattccatctcacaactgaacacatttaaa
gaagactgctccaggagccatttgcccgaggttatctcaatagcaagggagaaaatagtg
agcgacgagaacagtaatgaaaggtgctgggagcagagcgtgccggagtcgatgaagaac
cttaacattagctgcagcagcttgctgagaaaccatcagcatggcctgcccccgagccag
ttttatgaaacgtgtgactctgtcaccgagcaagacttgtgtttggaaactggaattcct
tctccactggaaagaaaggtgtttcctggaattcaactggaaatagctggacctcccatg
gatattagtcctttaggaaatcatccagcggttatggagactgatggatcacaccctggc
agcaacgtggcactattgcattttcattatgaggttgacagaagaacatcagacactttc
tgtaccatggcagaaaacttaaccttggatgattgtggaaactgtgtaccactgcctcct
gttgagggggagcagaagaaaaattacatggcatacacttctcaactggcgggcttggcc
caaagctgtgataatcagaatgggcagctgccgtgtggtcattgtgacaccttgaatgaa
aaatacttgtgctttgaaggcacttgccagaaggttgacggggtatgttcaagtgatagc
tttgacaaggaggattttactgccagtccgcctgccaagacctttttgagccaatttgag
cactttcctgataattgtgaagaggtagaagatttttttaaaagcaaaaaggaacgttcc
actttgctggtcagaagattttgtaaaaatgacagggaagttaagaaatctgtatatact
gggacaagagcaattgtgagaactctgccttctggccacattgggagggtcgcttggagt
tatgttgatcaaaagagaaatgctctcttagtatctcgtgggagagtgacagaacctctt
tcttctttggagatgaggcaaggtgggagccatcatttgtcagaagccccgtggtatctg
atctaccatgcagtgagaagagaagaaacagaaaatccagttggatctcttctccggttc
ttcacaaagctcccagcctcagagacagctcatgggagggtcagcctaggtccctgcctg
aagcagtgcgtccgagacactgtgtgtgagtatcgtgccaccctgcaaaggacctccatc
tctcagtacgtcaccggttctctcctggaagcaaccacgtctttaggaacaagaagtggt
cttctcagtacttttggaggttccgctggacgaatgatgctgaaagaacgccaaccaggc
acctctatggccagttccaatgccctcccttcaagttcagctggaatcagcaaggaactg
atcgatctgcagcccctcatccagttcccagaggaagtggccagcatcttaacagagcag
gaacagaatatctaccgaaaggtcttgcctgttgactacctttgcttcttaaccagggac
ttaggcacaccagaatgccagaggtccctgccctgtctcaaagcatccatctcagcatcg
attcttacctctcagaatggagaacgcaatgccctggaagaccttgtgatgagatttaat
gaggtgagctcctgggtgacgtggctgatcctcacagcaggctccatggaggagaagcgg
gaagtcttctcttacctggtgcacgtggccaaatgctgctggaacatgggcaactacaac
gctgtcatggagttcctggctggcctcaggtcgagaaaagttttgaaaatgtggcagttc
atggagcagtcagacatggataccatgagaagcctaaaggatgccatggccctgcacgag
tcctcgcgggagtaccggaaggcggtgacgcgagctctgcatatccccggctgcagggtg
gtgcccttctgcggtgtgttcctgaaggagctctgtgaggtcctcgacggagcttccggc
ctcatgaagctttgcccacgctacaattcccaggaggagactttagagtttgtagccgac
tacagtggccaagataatttcttacaacgcgtgggacagaatggcttaaagaattcggag
aaggagtccacggtcaacagcatcttccaggtcatcagaagctgcagtcggagtctggag
acagaagaggaggacagccccagtgaaggcggtggctccaggaaaaattccttgaaggac
aaagccaggtggcagtttataattggagatttgctggattcagaaaatgatatctttgag
cagcccaaggactgtgactcgcacggatctgaggagtcgcagaaggcctttgatcatggg
acagagctcatcccatggtatgtgctgtccatccaagctgatgtgcaccagttcctgctg
cagggggccacggtcatccactacgaccaggacacacacctatctgcccgctgcttcctc
cagcttcagcctgacaatagcaccttgacctggataaagcccaccactgcctccccagcc
agcactaaagcaaaacttggtatgcttagtaacacaaccgagcctggcaaattcccgtta
ctgggcaatgctggattaaatggcctagcggagggggtcttggatctgttttcagtgaag
gctgtgtacatgggacaccctggcattgatatacacactgtgtgtgttcagaacaaactg
agtagcatgtttctgtctgagaccggtgtgacactgctctatgggcttcagaccacagac
aatagattattgcactttgtggcaccaaagcacacagctaaaatgctcttcagtggattg
ttggaactcactaaagctgtgagaaagatgaggaagttccccgaccaaagacagcagtgg
ctgcggaaacagtatgtcagcctctaccaggaggatgggcgatatgaaggcccaacattg
gctcatgctgtggagttgtttggtggcaggcggtggagtactcgaaaccccagccctggg
acatcagcaaagaatgccgagaagcctaatgtacagagaaacaacaccctgggcataagc
accaccaagaagaagaagaaaatgcttatgaggggtgagagtggagatgcaacagatgac
gaaatggtgacccgaaagggcaagatgtacaaagagtgtcgaagccgcagcggttcggat
cctcaagacattaatgaacaggaggaaccagaggcaaatgccatctccagtcctcccaac
cccctcccttccagaagagcccactctttgaccacggctgcgtcccccaacttggctgcc
gggacgtcgtctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaacaagagc
ccgtccagtgcttggagcagcagcagctggcatgggcggatcaaaggaggaatgaaggga
tttcagagcttcatggtttcagacagtaacatgagttttgttgaatttgttgagctgttc
aaatcgttcagtgtaaggagccgcaaagacctgaaggatctcttcgatgtgtacgcggtg
ccctgcaaccgatctggctccgagtcggccccgctctacaccaacctgaccattgaggaa
aacactagcgacctgcagccagacctagatttgttgaccagaaatgtctcggatttggga
ttgttcattaagagtaagcagcaactgtcagacaaccagaggcagatctctgacgccatt
gctgctgcgagtatcgtgacaaatggcactgggatcgagagtacatccctgggcatattt
ggggttggaattctccagctcaacgacttcctagtgaattgccaaggagaacactgcacg
tacgatgacatcctcagcatcatccagaagttcgagcctagcatcagtatgtgtcaccaa
ggtctaatgtcatttgaaggatttgcgaggtttctgatggataaagagaattttgcctcg
aaaaatgatgagtcacaggagaacattaaagaattgcagctacccctgtcctactattac
attgagtcttcacacaatacctacctcacaggccatcagctgaaaggggagtcctcagta
gaactctacagccaggtcctcttgcaaggctgtaggagtgtagagttggactgctgggat
ggagatgatgggatgcccatcatttatcatggacatacactgacaaccaagatccccttc
aaggaagtagttgaagccattgatcgaaatgctttcatcacctctgacctgccgatcatc
atatcaattgagaaccactgttcattgcctcagcaacgaaaaatggccgagattttcaag
acagtgtttggggaaaagctggtggctaaattcttgtttgagactgacttctcagatgat
ccgatgcttccttcacctgaccagctgaggaggaaagtgcttcttaaaaacaagaagctc
aaggcccatcagacaccagtggatatcttaaagcaaaaggctcatcagttagcttccatg
caagcacaggcttataatggtgggaatggcaaccccccacctgccaataatgaagaagaa
gaagatgaagaggatgaatatgactatgactatgaatccctttcagatgcagacgtcctt
actgcttcccctgctcctaacggtcaggaagacaacattctggaagacagacctgaaaac
aagtcctgtaatgacaagcttcagtttgagtacagtgaagaaatccccaaaaggataaag
aaagcagataactcggcttgcaacaaaggaaaggtgtatgacatggaactgggagaggaa
ttttatcttcctcaaaataaaaaagaaagcagacagattgcaccagagctttctgacctc
gtcatctattgccaagctgtgaaatttccagggctgtcaactctaaatgcatctggctct
agcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcagaatg
agcccaggggagacagcatcgtttaacaaaacatctggaaaaagtttctgtgaaggcatt
cgccagaactgggaggagacgccctccgctctgaaccccgccacgtcgctcagcgctctc
attcgaactccccgatgctaccacatctcgtcgctgaacgaaaatgccgccaaacggctg
tgccgcaggtattcgcagaagctgatccagcacaccgcctgtcagctgctcaggacctac
ccggccgccacccgcatcgactcctccaaccccagccccctcatgttctggctccatggg
atacagctcgtggccctcaactaccagacggacgatctccctttgcatttaaatgctgcg
atgtttgaggcaaatggtggctgcggttatgttttgaaacccccagttctgtgggacaag
agctgtcccatgtaccagaagttttctccactggaaagggatctggacaacatggagcct
gctgtctactctttaactattgtctctggtcaaaacgtgtgccccagtaacagcacagga
agcccgtgcattgaagtggacgtcctgggcatgcccctggacagctgccatttccgcacg
aagcccatccaccgaaacaccctgaaccccatgtggaacgaacagtttctgttccgggtt
cactttgaagaccttgtgtttcttcgtttcgcagttgtggaaaacaacagttcagcagta
accgcccagagaatcattccactcaaggctttaaaaagaggatatcgacatcttcagctg
cgaaacctccacaatgaagtcttggaaatctccagtttattcataaacagcagaaggatg
gaagaaaatccctcaggcagtgccttgccagcctctttgatgtttaacacagaagaaaga
aaatgtttgcagactcacagagtcacggtacatggggtcccaggcccagagccctttgtg
gtttttactataaatggaggcaccaaggcaaaacagcttctccagcaaattctgaaaatg
gaccatgacaccaaacctgttgccacagactattttttgatggaagagaagtattttata
tctaaagaaaagaatgagtgcaggaagcagcctttccagagagccattggcccagaagaa
gagatcctgcagatcctgagcagctggttcccagaagaaggctatgtgggcaggatcgtc
ttcaaaactcagcaggaaatcccagaagagaaaaccattgttcaagatgacagagaggtg
atcttgagctcagaggaagagagcttctttgtccaggtgcatgacgtttccccagagcag
ccacggacagtcatcaaggcaccccgtgtcagcactgcacaggacgtcattcagcagacc
ttgtgcaaagccaaatattcctacagcatcctgagcaatcccaacccaagtgactacgtg
cttctggaagaggtggtgaaagacactggcaccaagaagtcttctaccccaaagccctct
cagcgagtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaaggtgcg
ggaaaattcatccttaagctaaaggaacaggtgcaggcttcccgagaagataaaagaaaa
ggcatttcttttgccagtgaactcaaaaagttcaccaagtcaactaaacagcctcgagga
ctcacatcaccttctcagctcttagcctcagaaaacatccaaaacaaggaggagaaaccc
atgtgtggtttgtcccctggagacacaatggattatcggcagtga
DBGET
integrated database retrieval system
