Oryctolagus cuniculus (rabbit): 100346489 Help Entry 100346489         CDS       T03373                                  Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ocu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100346489  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ocu03036]     100346489 Chromosome and associated proteins [BR:ocu03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100346489 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH Motif Other DBs NCBI-GeneID:  100346489 NCBI-ProteinID:  XP_051682360 LinkDB All DBs Position 20:11212520..11601767 Genome browser AA seq 6896 aa AA seqDB search MASSTVAPAEDQQVAVGIDDLHISLQAEQEDTQKKTFTCWINSQLAKHTPPSAVSDLFTD IKKGHVLLDLLEVLSGQQLPRDKGLNPFQCRINIEHALTFLKNRSIKLINIHVADIIDGN PSIILGLIWTIILHFHIEELARTLSCNYNEPAAAEVSVVDSSPTSSPPAKKCSKAQERWK LSAKKALLLWAQEQCATYESVSITDFKSSWRNGLAFLAVIHALRPDLIDMTSAKQRSNKD NLQEAFRIAERELKIPRLLEPEDVDVANPDEKSIMTYVAQFLQYSKDAPVTRDEAQGETK AAMDWLARQEKKLQKALKDSEHEPYFKKYHSFLSFLESFDEEKKPFLDLLPLTRPPDELS EEELRLRGDWDGLNQQINTWKTELNQALPSPLCHIEGWLQELEELVGEELPASQNYSEAM ILTQEKMTLFKSLMDRCDSNSNTLMAFENRDEKHLPLVPPNKLEEMKRRLNNILERRFAL LLEFHYYKCWVLGLLEEVKSKLDVWNVRYGNKASVELLQEDWHKFIEEKGFLVQLDTSFQ KCEEIYKHLAGECQNINEQYTVMESNICMYKKYLYNVKSTLQKVLASWATYMEKLRSLKA CFEETKKEQIKEVPFEILSQWNVEHITLNEVGNFLIGVSNDEVGASISKELRRLNKRWRK FISKTQLEMKLPLIKKQDQPIPDTSGNILPSKEEKPTADVLTDASTELSGDHDWNIRAGG EGEKEKEEFPGQLKVAEEVEKLSGRVEIWEAETASVLDLLRQGDDAGTSMEEPLQHLLAK GSMYEELVARTEDTLQMDIQNISSQESLQHVLTAGLQAKIQEAKEKIQINVVKLMAASKT SSDVSAGLDARLQLEESRKELESHMAKAEQLLEQRERPGALISKYKEALILLNTKCMAKY LRAVEEMKGSVTEDVQLSWEEESRAVCAKWESLHHELSLYIQQLKIDIEKGKLSDTISKL EKQINKEKKLIRRGRTKGLLQEHEACFSKEGILPQLHQHMDVLRELCEELPSQHSQQEGK RALRDYEQKIERLLRCATEIHATLQATAGDPSGNKGTVATTENGGRDSHGEVPFAKPDHQ PPTEQAMEPANFVPASEVKPQQEASVAEQHEKEHSLTLDSLQKRYVTQKEILELHLQSNK FRITSAFSSENEESSACLRDKLTDLQGLKNETDAYWKEFEITSLKLENLVSDVEKPAIVK ARDGLKEKEGELHLTLHARLKSLETALQTVSPVERETVFLCGLDLSLPEIVIQDFHLVNV DGIYQHLRDIQDSVAKQIEICNEELDSFASKELHPSDVQAAQNITLTCKAQLEGMSHKVQ TRDGALRALEDFLECLGTAKPSAEGTADRPAEQNPEAPGNASNAENEVGATQLLKDRARH LDESLEVLGVSLKDVQQGEDTSCEKLLEASSLRVLGSCGSSPREELTEEARLLEACILRN NELFKNIQDVQSQIGKLGLKDPTIPAVKHRKKSLIRLDKDLDGYEEEKKHLQELALSLPQ FHDGRELVLSQQCHRTVRLWENTKAALAECLEQCGRVLELLKQYHNFKSSLTTLIQKEEN AISLQASYMGRENLKKRITEIETIKEEFNEHVEVVDKINQICKNLQFHLNKMKTFEEPPF EKEANIIVDRWLDINEKTEDHYENLGRALALWDKLYNMKNVCDEWTEEVVQKMELHPLTA EDRDRLEEELQVHEQKVAEFSRRVAEIQFLLQSSEKPLELQVMESSILKQMEQVKQCLTG ASSCSALADNAAELREDLDQAKTQIGVTESLLKALSPSDSLEIFTKLEEIQQQILQQKHS MTVLETQVGCMTPELAELKKQYESVSDLFTAKKSVLQDHFSKLLNDQCKNFNDWFSNVKM NLKECFESSETKKNVEQKLQKLSDFLTLEGRSSKIQQVETVVRHVTKHLPHARVAELNSW LLSQELELGQMESVCRARAKELAELLQQLLRLQDDHRNLSKWLTNQEDKWKEMQESGEKA ELFCQALARKREQFESMAQLNNSLKEQGLTEEEDIIMESARLIDKYQTLLRQGHGIEEEA QLAPAEDQGFNDLAHDVIHWIKEIKESLMALNSSEGKMPLEERIRKIKEIILLKPEGDAK IQTLLREAGSSEALSVQETLGDIRSQWDSTLHLASTYLSHQEMLLLEGEKYLQSKEDLRL MLTELRKKQEAGFALQHGLQEKKAQLKICKKFLEKAQDLTSLLKELRAQGSYLLQCTNNP SFSEEPWLEIKRLHQSLLQQLQDSVQKLEGHVQEHQSYQVCLTESNAALDSLSKELASFA DQPVDRIAVEEKLQKLEEFQHQLSLQGGALDKISALAKSVQQNTSSVGQKVIKEDVKSLQ HKQKDLESRIESAKQEAESQLHSAHLQLQRAKEGTGELTVPGGEQQEGSPEEAAAVGKLE EDGDINKNSAVEMILSKQLSLGVQESMKNSEDEQKVRGLQDQPLELDVVLRNEQLKEIEE LYAQLEAKRAAIETLAEASALGLHDTGDPAQHLDTLLQALATLKEDRESQYCLLADFQGQ LSVAATSVKAWLAEKENLKGGSLDIAAHLDKIKKLLASIEEEKGLLSKLKMEWENVSEHL TGMDQKLLESQMKQLERGWEQVEQLLQKKYSQRAVERDAFASLVSKIRDLEMSLQKQQQR LRSRLSSAGAQEGDQSVVASATELQTLKQGFSVLKGQAELQMKRLWGEKDKTILEDAINN LKSQLDALEPLSLEVENQMKKCEMSSEVRETILWVKNLLGELVHPVSLLPEDILSQIRKR KVTHDSILEKQQAVESLAEKVKDHISNLPADESSDLQYLLEYLQNQYQMLVLKSTERSQQ LECQLEERSRLFAVIGKVHSTLQESEMLMTDKMGATCTEAELGRHLVTLKGSQEELQEVE RLISTQLPELATISEDLNVFERLFLDDQLKNLKTRVSRTQRFIENRCGEVEHKVKFFREF QEKISVLQKEVDDLQHKELLLTQEINQDAKQEFRTLKDRLAGIQCGVLQMLKLKEVFEIM GLEWDHSRLDQLQSQVNEKEKELEEQMKQVDLFVTARDKYQESLDNMRAVDLHVENRAEG LLNAPGASPESCLLQAQILDQRLEKTKCSYDDLMKQLTESEAFDDSFKEKEIAHIMQKAE EKDNLRKLLQNMISHFQPKDTDEKNLQDRLERSLRLLNQIERQLQQPLLIHLDVAHIQNE KDNCEAFWEQVQAEMCAVRAVAVPETQREERTPPESRGVHATLRDVEDLQRQLRTSIDLR KNVLSDAHENVIRYNEAVTRAVGIIASLGATCASHPVDLDNLEESLAAPRRKQEELESTL ADIQGLAERLGTVCSPQAQRQLQCTLQELVAKKSALQEAARGADAEQARYLQNYKNYGKI KEKICANLKKMGTVLGQSISPLPVSYKEALERLEESKVLVSNAESAEEDLLELRQVVRRL SARCTEGDRVHLQRILLALWEEWLRLLEAARAWEMWCETLKQGWKFVSEEMEREAIILDN LQEELPEVSKTREAAPKEELCELLESLSQCEQHVEKQQLLLNLLLERMKSVQNVPEGPGA GTTTPALQEVTSMHDRCNRLFQKVQKSKELMQTEIQERHAFTREIVALKHLFQQTATSFQ NATQEHPLKAEQLEELQSILREGKRTFETLMEKLRIKYSEMYTIVPAEVGSQVEECRRAL EDTEEKISNEVLKSSPSYAMSRKIEEINSGLQNVEKMLQQKSKNIEKAQEIQKKTWDELD LWHARLNELDAEVQDVVEQDPVQAQEWMDHLMIPLQRYQQVSQRAESRTSQLNKATIKME EYSELLKSIEVWVENTSRLLANPADYDSAKTLSHHASTLQMALEDSEQKHSLLHSVLTDL EELSTIFDTDDLTQSIQGLSSQITALQQKLLESLPQIQRMADDVVAIESEVKSMEKKVSK IKTILLSKEIFDFSPEEHLKHGEVILDNLRPMKKTIAEIVSYQVGLRLPQAGRGPLPVFQ RTSQLLQDLKLLENVTQEQNELLKAVIKQTNEYDEEIQKFQQILSDHADDVSREHTSAGQ AAHLPQAQGEVEQAQKQILSLNQKKEEVLGDLKTAVLTLHRHLKQDQEEGERQLLPAGAS EEGGVAEGDISEWQVNPRGSMSFLPALKEEVEEGSVKSETGDKKAEPSSASWSLPWKHGE EVEEDRASSSSATLVQEVNGKISTCDSSMAQILVPATPNTEQGPEFSLRPGQTEEGAAPP IQVLDFSEEPGAAGATVERGGPELAEVLHACRSQVAELELWLQQANVAFEPETLNADMQQ VVEQELVGCQAMLTDIEHKVASLLETCRDQSLGESGAIQYEAEALSLKLRTVKCNLEKVQ MMLQEKYSEDQHPTILKKPPDHQGVLQPGDLSEWERTETERPQFHRQKDILEPQVMELKP MEQKDLIKFIEFNTKKMWPQDCQHEKDPTQESSMSNRASSPENDAPDSVSWPQGRSGGRW LYLHRKLSSRTRPALPQLVEPQVATNTSILPSVSVYNFKYPTTEELKTYTTQLEDLHQEA STLQTQEPMTEDRCSGLDKKLFELFLPLSQHLDLVEELLQTPGLVREDVSAQQVHYETLA LELKKLYLSLSNKKGDLVKAVTWPGRNTSLLLECLEQLQACLEHARATAVSRGKSLKAGL DYKRSYQSEIKRLYDQLTQKKTSLQQSLNEMSGQAVGEQLQKADACTAELQNSESRVAKL RAEGERLHLPWALLQEVSKLEDVLDSMWAILRSRYSALSSPFVSESQQDALLRGVEELVR IGKEKLSHDHLQPAKSKAALQAQAQSHKVFFQKLLADMLFIQTYSSKVSPLLQKREGFWA EQVAEVKLLEEESRQRGVALQSLLQKWEAFDENYACLEKDLEILLSTLPSVSLVEETEER LAERISLYQQIKRNVDGKHVRLYQTLNEGKQLLATVSCPELGGQMAKLEEQWLSLDKRLD RELHRLQTQLKHLRSYNRDSDELTRWLGSAQQTLNHWKEQSLNVSQDLDTVRSNISRFFE FTKEVDEKSSLKTAVVSTGDQLLHLKEADTATLRACLAQFEQKWTLLITQLPDIQEKLHQ LQMEKLPSRKAITEMIDWMDSMESALEGAELSPGSAAQVRSLLRKHKEFRMEMDYKQWIV DFVNQSLLQLSTCDVESKRYERTAFAEDLGEMNRRWHQVHGALNRKIQHLEQLLESVTEH ENKIQMLDNWMEAQEERLRTLQRPEAVVSVEKVLLECQDIENQLEIKSKALDELRQSSLT LESGGAPLVKDATSRIHELFQKRARVTSQINQLKNSMQSVLREWKTGNRLCSEMEVMTVR FRYCLELGKPLISSLEALGCQVQNLQALQDEAESSEGSWEKLQEVTRKLQGFCPAVAELI REKCQATLSRWTQVNQEIAEQLQKAQSALQLWRTYHSAHSEASARLQQQEAKFQQLATIN MSGNNLAETLPLALQDIKELHRDVQETREAFARSSALLDRLPQPAESSAHAFLSGQPHSL QRAAFLEKTLLMKASEFEFVLSQLKEFWDQLESLQGLMHEKENVDKLHQQEREENPNSLL NRVLALTAHSPDLERLNEVSLKLPLSEVAVKTLQSMNRQWIQATATAMDRCRELQDAGLK ENFLYCCEKWVRLLEKMEEKLGGSAGDSLAALLEEQKTFQMLEAEVSISQRVADVWVTQS LQLLDTAEVERSPEFVAGFSELADRWQRAAQGVRQRAREAEGLVRKWWCFTASAEELLRF LADTSHLLSALKGRDHYSLSQTRSLLQELKNKEIHFRRWQTTYALTLEAGGKLQDMSDQE SRASVGETMSQLQDSWTSTELQLGEMVQQFQGTLEAWEQCGKKLQELKSRLQGVKVQSRA SLPELHEDLQKEKERIKDLEKSLATWSQNWQELEAVQAELGRRALAEDAMGLRQQMEHLH RQWDDLCLRVAMRKQEIEDKLNSWILFNEKNKEVCAWLVQMENKVLQTADISIEEMIEKL QKDCMEEINLFSENKLRLKQMGDQLIQASNKTRAAEVDDKLNKINDRWQHLFDVIGSRVK KLKETFAFIQQLDRNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDLQRDIEQ HSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRMKIEETW RLWQKFLDDYSRFEDWLQSAERTAACPNSSEVLYTNAKEELKRFEAFQRQIHERLTQLEL INKQYRRLARENRTDAASKLKQMVHEGNQRWDSLQRRVTAILRRLRHFTNQRDEFEGTRE SILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKIDQLIVCGEQLIQKSE PLDAVLIEDELEDLHRYCQEVFGRVCRFHRRLTSPAPGLEDEKETSENETDMEDPREMPP DSWRKRGESEEPPSPQSLCHLVPPAPGHERSGCETPVSVDSIPLEWDHTGDVGGSSSHED DEEGPYYSALSDVEIPENPEAYLKMTTKTLQASSGKSISDGHSWLVPDSPSCPKHRYKQM EGDRSGPPVPSDSSTPYKPAYVKLLLRPSAEGGKEGPTVLNGSRQPEDERGAGVTGQQPG TLDRWELIQAQELHGKLRMKQSWRQLDSDIGSIAAWLANTEAEMETLQTAEPPSDVQEMG LRVRRLQEIVKASDTYKALLDSVHGSSQESLPSESAEAAELQSRLHQLRVRWEAAQGAVD SWRAGLRQSLMQCQDFHQLSQNLLLYLASAEGRRQEAHVADPKADPQVLLECQRRLMQLQ KELVEHQPQVNSLREIANSLLVKGPGEDYIEAAEKVHVIEKKLHQLLEQVAQDLMSLQGS QTQDPALPAVDEVDSGQQPPAASMPAPRARLGAEKTTRGRKEADSRVPGPGSSRPPRSFL ARVLRAALPLQLLLLLLLLLACLLPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT NT seq 20691 nt NT seq  +upstreamnt  +downstreamnt atggcgtccagcactgtggctcccgccgaagaccagcaggtggccgtgggcatcgatgat ctccatatttcactccaagcggaacaggaagacactcagaagaagaccttcacctgctgg ataaactcgcagttggcaaagcacacgccgccctcagctgtgtcagacctcttcaccgac attaaaaagggccatgtgctcctggacctgctcgaagtactctcgggccaacagttgccg cgggataaaggacttaatccgttccagtgcagaatcaatatagaacacgccctgacattc ctgaagaaccgatcgatcaagctcatcaatatccatgttgctgatatcatagatggaaac ccatccattatcctcggccttatttggacaataatactgcatttccatatcgaggagctg gcccggactctttcttgcaattacaatgaacctgccgcggctgaggtgagcgtggtggat tcgtctcctacctcaagtcctccagctaagaagtgctccaaggcccaagaaagatggaag ctgtccgccaagaaggctctcctgctgtgggcccaggagcagtgtgccacgtatgagtct gtcagtataacagatttcaaatcaagctggaggaatgggctggcctttctggctgtcatt catgccttgcgtccagacctaattgacatgaccagtgcgaagcagaggtccaacaaagac aatctccaggaggcctttcgaatcgcagagcgagaactcaaaatccccaggctgctggaa ccagaagatgtggatgtcgccaatcctgatgaaaaatccatcatgacctatgtggcacag tttctgcagtattcaaaggatgcccctgtgacgagagacgaggctcagggagagacgaaa gccgctatggactggctggctcggcaagagaaaaaactgcaaaaggcgctcaaagattca gaacatgagccctactttaaaaagtatcacagcttcctgtcctttttggagtccttcgat gaagaaaaaaaacccttcttggacctcctgccgctcacaaggcccccagatgagttgagt gaggaggagttgcggttgcgaggagactgggacggcctcaaccagcagattaacacgtgg aagacagagctgaaccaggccctgccttcgcctctctgtcacattgaagggtggcttcag gagctggaggagcttgtgggtgaggagctgcctgcctcccagaactactctgaagccatg atcctgacccaggagaaaatgaccttgttcaagagtctgatggatagatgtgacagcaat tcaaatacgctcatggcgtttgaaaacagagatgaaaagcacctgccattggtgccgcct aacaaattggaggagatgaagagacgactgaacaacattttggagagaagattcgctttg cttctagaattccattactataagtgctgggttcttggtttgctggaggaagtgaaatcc aagttggacgtgtggaacgttcgctacgggaacaaggcctcggtggaattgctgcaggaa gactggcataaatttattgaagaaaaagggttcctagttcagctggatacttcttttcaa aaatgtgaagaaatttataagcatctggctggagagtgtcagaatatcaatgaacaatac acagtgatggaaagcaacatttgcatgtataaaaagtatctatataatgtaaagtccact ctgcagaaagtgctggcgagttgggcaacgtacatggaaaagcttcgctcactgaaggct tgttttgaggagacaaagaaggaacaaattaaagaggttccctttgagatcttatcccag tggaatgtggagcacattactttaaatgaagtggggaatttcttaattggagtcagcaac gatgaagtgggagcatctatttctaaggaactgaggcggctgaataagcgatggagaaag ttcatttcaaaaactcagctggaaatgaagctcccacttattaaaaaacaagatcagccc attcccgacacttctggaaatattctaccatctaaagaagaaaagccaactgctgatgtt ttgacagacgcatcgaccgaactttctggagatcatgactggaacataagggctggagga gaaggtgaaaaggagaaggaagaattcccggggcagctcaaagtggctgaagaggtggag aagctcagcggacgggtggagatctgggaggcggaaaccgcgtctgttttggatcttctg aggcagggagatgacgcggggacatccatggaggaacccttgcagcatctccttgccaaa ggctccatgtacgaagagctagtggccagaaccgaagatacattacaaatggatattcag aatatttccagccaggagtcccttcaacacgttctcacggctggactacaggccaagatt caagaagctaaagagaaaatccagatcaatgtggtaaaactcatggcagcatcaaagacc tcaagtgatgtttcagcaggcttggatgccaggctgcagctagaggagtcacggaaggag ctggaatcacacatggccaaggctgagcagctactggagcagcgagagcgccccggtgcc ctcatctcaaagtacaaggaagcattaatacttcttaatactaagtgtatggcgaagtac ttgagagctgtggaagaaatgaagggtagtgtaacggaggacgtgcagctgtcttgggaa gaagagagcagagctgtctgtgccaagtgggagtctcttcatcatgagttgtctttgtat attcaacaactgaagatagatattgagaaaggaaagctgagtgacacgatttcaaaactc gaaaagcaaataaataaagagaagaaacttattcgcagaggaaggaccaagggcctgctc caggaacacgaggcttgcttctctaaggaaggcatcctgccccagctccatcagcacatg gatgtcctcagggagctgtgtgaggagctcccttcacagcacagtcagcaggaagggaag cgagcactccgggactatgaacaaaagatagaaagacttctgagatgtgcgacggagatt cacgccaccctgcaggccaccgcgggagacccgtcggggaacaaggggactgtggccacg actgagaatggaggaagggattcccacggggaggtgccatttgcaaaacctgatcatcag ccgccaacggaacaggcgatggagccagctaacttcgtgcctgcatcggaggtaaagcct caacaagaagcaagcgtcgcggagcagcatgagaaggaacacagcctcactctagacagt ttacagaagaggtatgttacacagaaggaaattcttgaactacaccttcaaagcaacaaa ttcaggataacttctgcgttctccagtgaaaatgaagagagtagtgcttgcttacgggac aaactgaccgatctccagggcttaaaaaatgaaactgatgcttactggaaggagtttgaa atcacctccctgaaattagaaaatcttgtgagtgatgtggagaagcctgcgatagttaag gcacgagatggactaaaggaaaaagaaggggagcttcacctaacccttcacgccaggctg aagtctttggagacagcactgcagactgtgtcccctgtagagagggagacagtgtttctc tgtggcttggatttgtcccttcctgaaattgtcatccaggactttcatcttgtcaatgtt gatggcatctatcaacacctgagggacatccaggactccgtagcaaagcagattgaaatc tgtaatgaagagttggacagcttcgcatcaaaggaattgcacccatctgacgtgcaggca gcacagaacattacactgacctgcaaagcgcaacttgaaggaatgagccacaaggtgcag accagggacggcgccctcagagctctggaagactttctggaatgtctaggaacagctaaa ccctctgctgagggcaccgcagaccggccagccgagcagaacccggaagcaccaggaaac gcctccaacgcagaaaacgaagtgggcgcaactcagctgctgaaagacagggccaggcat ttggacgaaagtttggaggtgcttggcgtcagccttaaagatgtgcagcaaggcgaagac acgtcctgtgaaaagctgctggaggcttcgagcctgagggtactggggtcctgtggctcc agcccacgggaggagctcaccgaggaagccagattactggaagcttgcattctcagaaat aacgagctcttcaaaaacattcaagatgtacagagccagatcggtaaacttggccttaag gaccctaccatcccagccgtgaagcatcggaaaaaatcattaatcagactggataaggat ctggatggatacgaggaagagaagaagcaccttcaagaattggctctttctctcccgcaa ttccacgatggcagagaactcgtactgagtcagcaatgccaccgtaccgtgcgcctgtgg gagaacacgaaagctgcgctggccgaatgccttgaacaatgtggaagagttttggagctc ctaaaacaatatcataattttaaaagcagcttgaccactttgattcagaaagaagagaac gccatctccctccaggcttcgtacatgggaagggaaaacctgaagaagaggatcacagag attgagacgatcaaggaagaatttaatgaacatgtagaagttgtagacaagataaaccag atctgcaaaaatctacaatttcatttaaataaaatgaaaacctttgaagaaccacctttt gaaaaagaggctaatatcattgtggacagatggcttgatataaacgagaagacagaagac cactatgaaaatcttggtcgcgctctagctttgtgggacaaactttataacatgaaaaac gtctgtgatgagtggaccgaagaggttgttcaaaagatggagctccatccgctgactgct gaggacagagacaggctggaggaagagttacaagtccacgagcagaaagttgcggagttt tccaggagggtggctgaaatacagtttttgctgcaaagcagtgaaaaaccacttgaactc caggtcatggagtcctctattttgaagcagatggaacaagtgaaacagtgtttaactgga gcttcgagctgttctgcactggcagacaacgctgccgagctgcgggaggatctagaccag gccaagacccagattggggtgacagagtccctcctaaaagccctgtccccttctgacagc ttggaaatcttcactaagcttgaggagatccagcagcagattctgcagcagaagcacagt atgactgtccttgagacgcaggtcggctgtatgactcctgagctcgcggagctgaaaaag caatacgagagcgtcagcgatttgttcactgccaagaagagtgttctgcaggatcacttt tccaagttactgaacgatcaatgcaagaacttcaacgactggttcagcaacgttaaaatg aacctcaaggagtgtttcgagtcatcagaaaccaaaaagaatgtggaacaaaagctacaa aaactttctgatttcctgaccctggaaggaagaagcagcaaaatccagcaggtggaaaca gtcgtgagacacgtgaccaagcatctgccccacgcgcgtgttgcagagctcaacagttgg cttttgagtcaagaactggaactgggacagatggagtctgtgtgccgggctcgagccaag gagctggctgagctgttgcagcagctcctgagactccaagatgaccacagaaatcttagt aaatggttgactaatcaagaagataagtggaaagaaatgcaagaatcgggagagaaagct gagctgttttgccaagctttggctagaaagagggaacaattcgaatctatggcccaattg aacaactcattgaaggaacaggggctgaccgaggaagaagacataataatggaatcagca cgtttgattgacaaataccagacattattgagacaaggacacggaattgaggaagaggcc cagttagcacctgctgaggaccagggttttaatgatcttgcacacgatgtaattcactgg ataaaggagattaaagaatcgcttatggctttgaattcatcggaaggcaaaatgccgctg gaggagaggatccgaaagataaaggaaatcattttgctaaaacctgaaggggatgccaaa atacagaccctcctgagagaggccgggagcagcgaggccctgtctgtccaggagaccctc ggcgacatcaggagccagtgggacagcacgctgcatttagccagcacgtacctgagccat caagaaatgcttctgctcgagggagagaagtacctgcaaagcaaggaggacctgagactg atgctcacggagctgaggaagaagcaggaggcgggctttgctctgcagcacggcctgcag gagaagaaagcgcagctgaaaatctgtaagaagttcctggagaaagcgcaggacttgacg tccttgctgaaggagctgagagctcagggaagctacctgctgcagtgcaccaacaacccc agcttcagcgaggagccctggctggagataaagcgtctacaccaaagtcttcttcagcag ctccaggactccgtgcagaagctggaaggtcacgttcaggagcaccagtcctaccaggtt tgcctcacggaatcgaatgccgcgctggacagtctctccaaggaactcgccagttttgcc gatcagcctgtggatcgaatcgcagtggaggagaagctgcagaaactagaggagttccaa catcaactcagtttacagggcggcgcgttagacaagatttcagctttagccaagtccgtc cagcaaaacacgtcgtctgtgggacagaaggttatcaaagaggatgtaaaatcacttcag cataaacaaaaagatttggaaagcagaatcgagtctgctaagcaggaggctgaaagtcag ctccacagtgctcacctccagttgcaacgcgcaaaggaagggacaggggagttgactgtg cccggcggggagcagcaggagggcagcccggaggaggcggctgcagtgggaaagttggag gaagacggagacataaacaagaattcagctgtggagatgattttgtcaaaacaactttcc cttggcgttcaagaaagcatgaaaaacagcgaagatgagcagaaagtcagggggctgcaa gatcaacctttagaattggatgtcgtgttaagaaatgaacaattaaaagagatagaggaa ttatacgcccagctggaagcaaagagagcagccatcgaaacactggccgaagccagcgcc 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gagtatttacagaatcagtaccaaatgctagttctaaaatcaacagaaagatcccagcag ttagaatgtcaactggaagagagaagcagacttttcgcggtgatagggaaggtgcattcg acgctgcaggaaagtgagatgctgatgacagacaagatgggagccacctgcacagaagcg gagctgggacgccacctcgtcactttgaaaggatctcaggaggaactgcaggaagttgag aggctaatctcaacacagctcccggaactcgccaccatctccgaggatctcaatgtgttt gaacgattatttctggatgaccaattgaaaaatcttaagactagggtcagcagaacacag agattcatcgagaatagatgcggggaagtagaacacaaagtaaagtttttcagagaattc caggaaaaaatatccgtgctgcagaaggaagttgacgatctacagcacaaggagctgctg ctcactcaagaaataaaccaggatgcaaaacaagagtttcgcactctgaaagacagactc gccggtattcagtgcggcgtcttacagatgttgaaacttaaagaagtgtttgagattatg ggcctagagtgggatcattcgcgactggaccaattacaaagccaagtgaatgaaaaagaa aaggagcttgaagaacaaatgaaacaggtggacctgtttgtgaccgcgcgtgacaaatat caggagtccctggataacatgagggctgtggacctgcacgttgagaacagggctgaaggc cttctgaacgctcctggcgcatcaccagaaagctgtctgctccaggcccagattctggac cagagactcgagaagaccaagtgctcatacgatgacctgatgaagcagctgactgaaagc gaggccttcgacgactcattcaaagagaaggaaatagcacacataatgcaaaaagcagaa gaaaaggataacttacgcaagctcctgcaaaacatgatctcacacttccagccgaaagac acggatgagaagaatttgcaggacagactcgaacgttccttacgtcttttaaatcagata gaacgtcaactacagcagcctttacttatacacttggacgttgcacacattcaaaacgaa aaggacaactgtgaagcattttgggagcaggttcaggcagaaatgtgtgctgttagagct gtggctgtgcccgagacgcaaagggaggagagaacccctcctgaaagcaggggtgtgcac gcaacactgcgtgacgttgaagatcttcagaggcagctccgcacaagcattgacttgcgc aaaaatgtgttgagtgatgctcatgaaaatgtcattcgctacaacgaagcagtcaccagg gcagtggggatcatcgcgtccctcggagccacctgtgcatcgcacccagtagacctggac aatctggaagaatcactggcagcgcctcggcgcaagcaggaggagctggaatccactcta gcggacatccagggcctcgcggagaggctgggcactgtgtgcagcccccaggcccagcgg cagctgcagtgcactttgcaggaactggttgcgaagaagtcagccttgcaggaggcagcc agaggagcggacgctgagcaagcaaggtatctccagaattacaagaactatgggaaaatt aaagagaaaatttgtgccaacctcaagaaaatggggacagtgcttgggcagtccatctcc ccactgcctgtgtcttacaaagaagccctggagcgcttggaggagagcaaggttctggtg tcaaacgccgagtcagccgaggaagacctgctggaactacgccaggtggtcagacgcctg agcgccaggtgcacagagggtgacagagtccatttgcagcggatcctgctggccctgtgg gaggaatggctgaggctgctggaagctgccagagcgtgggagatgtggtgcgagaccctg aagcagggctggaagttcgtcagtgaagaaatggaacgagaagcaattattttagataat cttcaagaggaacttccagaagtttccaaaacaagagaggcagcccccaaagaggagctg tgtgagctgttggagagcctgagccagtgtgagcagcacgtggagaagcagcagctgctg ctgaacctcctgctcgagcgcatgaagagtgtccagaatgttccagaaggccccggggct gggacgaccaccccagcactgcaagaggtcacttctatgcatgaccgatgcaacaggctt tttcaaaaagtccaaaaaagtaaggaattgatgcagactgaaatccaggagagacacgcc ttcacgagagaaatcgttgctttgaagcatttatttcaacagactgcaacttctttccaa aatgcaacgcaggagcacccgttaaaggccgagcagctggaggagctccaaagcattctt agggaagggaagcgaacctttgagactctgatggagaagctgcggatcaagtactcggag atgtacaccatcgtccccgcggaggttggctcccaggtggaggaatgccggagagccctg gaggacaccgaggagaagatcagcaacgaagtcttgaagagttccccgtcatatgccatg agtagaaaaatagaagaaattaacagcggacttcaaaatgttgaaaagatgttgcagcag aagagcaaaaatattgagaaagctcaagaaattcaaaagaaaacgtgggatgagctcgat ctctggcacgccaggctcaatgaactggatgctgaagtccaggacgttgttgaacaggac ccagtgcaggcccaggagtggatggaccacctgatgattcctctccagcggtatcagcaa gtgtcccagagagcggaatccagaacctcgcaattaaataaggccacgatcaagatggag gaatacagtgagcttctgaagagcattgaggtttgggtagagaataccagtcgtctgctg gccaatcctgctgactacgactctgccaagacactgagtcaccatgctagcaccctccag atggctttggaagactcagaacagaagcacagtctgctacactctgttctcacggacctg gaagagctgtccacaattttcgatacggatgacctcacgcagtccatccaggggttgagc agtcaaatcactgctttacagcagaagttactggagagccttccacagattcagcgcatg gctgatgatgtggtcgctattgaatcggaagtaaaatcaatggagaaaaaagtctcaaaa attaaaactatcctgctatccaaagagatatttgatttttcaccagaagaacatctgaaa catggggaggtcatcctggacaacctgcggcccatgaagaagaccattgctgagatagtg tcttaccaagtggggctgcggctgccgcaggcgggaaggggccctctgcccgtgttccag cgcacaagccaacttctccaggacctcaagctgctggagaacgtgactcaggagcagaac gagttactaaaggcagtcataaaacagactaatgaatatgatgaagaaatacagaagttc cagcagatcttaagcgatcacgcagatgacgtctcccgtgaacacacgtcagcaggccag gctgcccacctgccacaggcccagggagaagtggaacaggcgcagaagcagattctgagt ttaaaccagaaaaaagaagaggtgttgggggacttgaagactgctgtgctaacccttcac cggcatttgaagcaagaccaagaagaaggggaaagacagttgcttccagccggagcgtcc gaggaaggtggcgtggccgaaggggatatttctgagtggcaggtgaacccgagaggctcc atgtctttcctgccagcactcaaggaagaggtggaggagggctccgtgaagagcgaaact ggagataagaaggcggagccatcttctgcgtcgtggtctttaccctggaagcatggcgag gaggtggaggaagaccgagcatcctcatcgtcggccaccctggttcaggaggtgaatgga aaaataagcacctgtgacagttccatggcgcagattcttgtaccagccacaccaaacacc gagcaaggcccagaattctcgctgaggcccggccaaacagaagagggtgccgcgcctccc atccaggttctggacttttctgaggagccgggagctgccggagccacggtggagagaggt gggcctgagcttgcagaagtcctccatgcctgcagatcccaggtagccgagctggagctg tggctgcaacaagccaacgtggcattcgagccggaaacattaaacgcagacatgcagcag gtggtggagcaggagttggtcggctgccaggctatgctcacagacatcgagcacaaggtc gcttccctgttggagacctgcagggaccagagcctgggcgagagtggagccatccagtac gaagcggaagccctttctctgaaactcagaactgtcaagtgcaacttggagaaggtccag atgatgttgcaagagaagtacagtgaggatcagcatcctaccattctaaagaaacctcca gatcatcaaggcgttctacaaccaggtgacctttcggaatgggaacggaccgaaacggaa aggccacagttccacagacaaaaagatatcctagaaccacaggtcatggagctaaaacca atggaacagaaagatttaatcaaattcatagaatttaatactaagaaaatgtggccccag gattgccagcatgaaaaagatccaactcaggaatcatcaatgagcaatagggcctccagc cctgaaaatgatgctccagactcggtgtcgtggccccagggccgcagtggcgggaggtgg ctgtatctgcaccgtaagctgtcatccagaaccagacccgccctgccacagctggtggag ccgcaggttgccactaacacgagtattctacccagtgtgagtgtgtataactttaaatac ccaacaactgaagaactgaaaacctacaccactcaactcgaagacctgcaccaagaagca agcaccctccagacacaggaacccatgacagaagacaggtgcagtggtttggataagaaa ttatttgagctgtttctgcccctcagtcagcaccttgaccttgtggaggagctgcttcag acgcctgggcttgtcagagaggacgtttcggcacagcaggtgcactacgagaccctggct ctggagttgaagaagctttatttatctctgagcaacaagaaaggtgaccttgtgaaggcc gtgacgtggcccggcaggaacaccagcttgctcctcgagtgcctggagcagctccaagcc tgcctggagcacgcccgggccacggctgtctctagaggcaagtccctgaaagccggcctg gactacaagcgcagttaccagagcgaaatcaagcggctgtatgatcagctcacccagaag aagacgtccttgcagcagtctttgaatgaaatgagcggccaggccgttggagagcagctg cagaaagccgatgcgtgcacagcggagctgcagaactctgagagccgagtggccaagctg cgagccgaaggcgagaggcttcacctgccgtgggctttgctccaggaggtttccaagtta gaggacgttctcgacagcatgtgggcgatcctcagaagcaggtactcagcgctcagcagc ccctttgtctcggagagccagcaggatgccttgttgcgaggcgtggaggagctagtgcgt atcgggaaggaaaagctttcccacgaccacctgcagccagccaagagcaaagctgctttg caggcgcaggcacagagtcacaaggtttttttccagaagcttcttgccgacatgttgttc atccaaacatactcttccaaagtgtctcctttgttgcaaaagagagagggattttgggcc gaacaagtggcggaagttaaattgctggaggaggaatcgcgccagcgtggcgtggcgctg cagagtttgctgcagaaatgggaagcatttgatgaaaactacgcgtgtcttgagaaggac ctggaaattcttctgtccacactgccctccgtgagtctggtggaagagacagaggaaaga ttagcagaacggatctcactctaccagcaaataaaacgcaacgtcgatggaaagcatgtc cggctataccaaactctgaatgaaggcaaacagctgctggccaccgtgagctgccccgaa ctagggggccagatggccaaactggaggagcagtggctgtcgctggacaagaggcttgac cgggagctgcatcgcctgcagacgcagctgaagcatctgcgcagctacaacagagactcc gatgagctcaccaggtggctgggatccgcccagcaaactctgaatcactggaaagagcag tccctcaacgtgtctcaggatctggacacagtcagaagcaacataagccgcttctttgag ttcacaaaggaggtggacgagaagtcctccctgaagacagccgtggtcagcaccggggac cagcttctgcatctcaaagaggctgacacggccaccctgagagcctgcttagcacagttt gaacaaaagtggacgctgctcatcactcagcttccagatattcaggagaagctgcaccag ctacagatggagaaactgccgtctcgcaaagcaatcacagaaatgatcgactggatggac tccatggagagcgccctcgaaggcgctgagctgtccccaggctccgcggcgcaagttaga agcctcctgcggaagcacaaagagtttcgaatggagatggactataagcagtggatagtg gactttgtgaaccagtcgctacttcagttaagcacctgtgacgtggagagcaagcgctac gagaggaccgcgtttgccgaggacctgggggagatgaaccgcaggtggcaccaagttcac ggggccctgaacaggaagatacagcatctagagcagcttttggaaagcgtcaccgagcat gaaaacaaaatacagatgctggacaactggatggaggctcaggaagagaggctgcggact ctgcagcgaccggaggccgtggtctcggtggagaaggtgctgctcgagtgccaggatata gaaaatcagcttgaaattaaatcaaaagcgctggacgagttgagacagagctccctgaca ctggagagcggaggggcgccactggtgaaggacgcgacatctagaatccatgagctattc cagaagagggcccgcgtgaccagtcagatcaatcagctcaaaaactccatgcagtcggtg ttgcgggaatggaagactggtaacagactctgcagtgagatggaggtgatgacggtccgg ttccggtactgcctggaacttggcaagcccctgatttcctcgctggaagccttgggatgt caggtgcagaacctgcaggctcttcaggacgaagctgagagcagcgaagggagctgggag aagctccaggaggtgactagaaaactccaaggtttctgccccgcggtggctgaactcatc cgcgagaagtgccaagctacgctctcaaggtggacccaggtaaaccaagagatcgcagag cagttgcagaaggcccagagcgcgctccagctctggaggacctatcacagcgctcactcg gaagcctcagcaaggctgcagcagcaggaggccaagttccagcagctggccaccatcaac atgtctgggaacaacctggcagagaccttgcccttggccctgcaggacatcaaggagctg caccgtgacgtgcaggagaccagagaagcctttgctcgaagctccgccctcttggaccgg ctcccacagcctgcagagtccagcgcccacgcgttcctctctggccagccccactccctg cagagggctgcgttcctggaaaagacgctgctgatgaaggccagcgaatttgagtttgtc ctctcgcagcttaaggagttttgggatcaactggaatctttacaaggtcttatgcatgag aaagagaatgtggataaactccaccagcaagaaagagaagaaaatcccaactcactcctg aaccgagtgctggcactgacggcccactcacccgatcttgagcggctgaatgaagtgagc ctgaagctcccactgagcgaggtggccgtgaagacgctgcagagcatgaaccggcaatgg atccaagccacggccacggccatggaccgctgcagggagctgcaggacgctggactgaag gaaaactttctttactgctgtgagaagtgggtccgacttttggagaagatggaagagaag ctgggagggagtgctggtgacagcctcgccgcactgctggaggagcagaagacgttccag atgttagaagctgaagtttccataagccagagagttgctgatgtttgggtcacgcagtcc ctacaactcctggacacagcggaggtagagaggagccctgaatttgttgcggggttctcg gagctggcggaccgctggcagcgagctgcccagggcgtgcggcagagggcgcgcgaggcg gaggggctggtgcggaagtggtggtgcttcacggcctcggcggaggagctgctgcgcttc ctggccgacaccagccacctgctgtctgccctgaagggccgggaccactacagcctttcc cagacccgaagcctgctgcaggagctgaagaataaagaaatccactttcggagatggcag accacctatgcgctgaccttggaggctgggggaaagttacaggacatgagtgaccaggaa tccagggcgtccgttggcgagaccatgagccagcttcaggacagctggacgagcacagag ctccagctgggagagatggtgcagcagttccagggcacgctggaggcctgggagcagtgt ggaaagaaactccaggagctgaagagcaggctgcaaggtgtgaaggtgcagagcagggct tctcttccagagctccacgaggacctccagaaggagaaggagcgcattaaggatctggag aagtctctagcgacctggtctcagaactggcaagagcttgaggccgtgcaggcggagctg ggccggcgcgccctggcggaggacgcgatggggctgcgacagcagatggagcacctgcac agacaatgggacgacctgtgcttgcgagtggccatgcgcaaacaggagattgaagacaaa ctcaattcatggatcctattcaatgaaaagaataaagaagtgtgtgcgtggctggtgcag atggaaaacaaagttctgcagaccgcggatatcagcattgaagaaatgattgagaagctg cagaaggactgcatggaagaaataaacttgttcagtgaaaacaagctgcggctaaagcag atgggtgaccagttaatccaggcgagcaacaagacgagggcggctgaggtcgacgacaaa ctcaacaagatcaacgaccgctggcagcatctttttgatgtcattggctccagggtgaag aagctgaaggagacctttgccttcattcagcagctggacagaaacatgagcaaccttcgc acctggctggctcgaatcgagtccgagctctccaagcccgtcgtgtatgacgtgtgcgat gatcaagagatccagaagcggctggcagagcagcaggatctgcagcgagatattgagcag cacagcgcgggggtggagtccgtgtttaacatctgcgatgtcctcctgcacgactcggac gcatgcgcaaacgagaccgagtgtgactccattcagcagaccaccaggagcctggacagg cgctggaggaacatctgtgccatgtccatggagcggcgcatgaaaatcgaggagacgtgg cgcctgtggcagaagttcttagacgactattcccgcttcgaggactggctgcagtcggcc gagaggacggcggcctgccccaactcctccgaggtgttgtacacaaacgccaaagaagag ctgaagaggttcgaggcttttcagcggcagatccacgagaggctcacgcagctggaactc atcaacaagcagtaccggcgcctggcgcgtgagaaccgcacggacgcggccagcaaactg aagcagatggtgcacgagggcaaccagcgctgggacagcctccagcggcgggtcacggcc atcctgcggcgcctccggcatttcacgaaccagagggacgagttcgaggggaccagggag agcattctggtgtggctgacggagatggacctgcagctgaccaacgtggagcacttctcc gagagcgatgcggacgacaagatgcgccagctgaacggcttccagcaggagatcacgctg aataccaacaagatcgaccagctcatcgtgtgtggcgagcagctgattcagaagagcgag cccctggacgccgtgctgatcgaggacgagctggaggacctccaccgatactgccaggag gtgttcggcagggtgtgccgcttccaccggcggctcacctcccccgcgccaggcttagaa gatgaaaaggagacctctgagaatgaaacagacatggaagaccccagagagatgccccct gactcttggcggaaaaggggggagagcgaggagcccccgtctccccagtctctctgtcac ctggtgcccccggcgcccgggcacgagcggtccggctgcgagacccctgtcagtgtggac tccatccccctcgagtgggaccacacgggtgacgtgggcggctcctcctctcacgaagac gacgaggaaggtccgtactacagtgcactatcagatgtagaaatccccgaaaatcctgag gcctatcttaaaatgaccacaaaaactttgcaagcgtcttctggtaaatccatttctgac ggccactcgtggcttgttccagacagcccgtcctgccccaagcatcgttacaaacagatg gaaggtgataggagtggaccgcccgtcccctcagactccagcacgccttataaaccagcc tatgtgaagctcctgttacgtccaagtgccgaaggtggcaaagaaggccctacagtcctg aatggcagccgacagccggaagatgagagaggcgcaggtgtaacaggacagcagccaggt accttggacagatgggagctgattcaagcgcaggagcttcacggcaaactcagaatgaaa cagagctggcggcagctcgactctgacatcggcagcatcgccgcgtggctggcaaacacc gaagcggagatggaaacgctgcagacggcagagccgccctctgatgtccaggaaatgggg ctccgagtgcggaggctgcaggagatagtaaaggcctctgacacctacaaggcgttgctg gactctgtgcacgggagcagccaggagtctctgcccagcgagagcgccgaggcggccgag ctccagagcaggctgcaccagctgcgcgtgcgctgggaggcggcccagggcgcagtggac agctggcgcgcgggcctgcggcagtcgctcatgcagtgccaggacttccaccagctgagt cagaacctgctgctgtacttggccagcgctgagggtcggaggcaggaggctcatgttgct gaccccaaggccgacccccaggttctcctggagtgtcagaggaggctgatgcaactgcag aaggagctagtggaacatcaacctcaagtgaactccttacgggagattgccaacagcctc ctcgttaaggggccgggggaagactacatcgaggccgcagagaaggtccatgtcattgag aagaagctccaccagttactggagcaggtggcccaagacctgatgtccctgcagggaagc cagacccaggacccagccctgcctgctgtcgacgaggtggactcgggccagcagcctccg gcagcgtccatgccagctccccgggcgaggctgggagcggagaagaccacacgaggcagg aaggaggcagacagcagggtgcccggccccggcagctcccggccaccgcgctccttcctc gcccgcgtgctgagggcagcactgcccctccagctgctgctgctgctgctgctgctgctg gcctgcctgctgccctcctccgaagaggactacagctgcacccaggccaacaacttcgcc cgctccttctacccaatgctgcggtacaccaacgggccgccccctacctag

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