KEGG   Oryctolagus cuniculus (rabbit): 100346742
Entry
100346742         CDS       T03373                                 
Name
(RefSeq) adenylate cyclase type 4 isoform X1
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00230  Purine metabolism
ocu01100  Metabolic pathways
ocu01522  Endocrine resistance
ocu04015  Rap1 signaling pathway
ocu04020  Calcium signaling pathway
ocu04022  cGMP-PKG signaling pathway
ocu04024  cAMP signaling pathway
ocu04062  Chemokine signaling pathway
ocu04072  Phospholipase D signaling pathway
ocu04081  Hormone signaling
ocu04082  Neuroactive ligand signaling
ocu04114  Oocyte meiosis
ocu04211  Longevity regulating pathway
ocu04213  Longevity regulating pathway - multiple species
ocu04261  Adrenergic signaling in cardiomyocytes
ocu04270  Vascular smooth muscle contraction
ocu04371  Apelin signaling pathway
ocu04540  Gap junction
ocu04611  Platelet activation
ocu04713  Circadian entrainment
ocu04714  Thermogenesis
ocu04723  Retrograde endocannabinoid signaling
ocu04724  Glutamatergic synapse
ocu04725  Cholinergic synapse
ocu04727  GABAergic synapse
ocu04742  Taste transduction
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04911  Insulin secretion
ocu04912  GnRH signaling pathway
ocu04913  Ovarian steroidogenesis
ocu04914  Progesterone-mediated oocyte maturation
ocu04915  Estrogen signaling pathway
ocu04916  Melanogenesis
ocu04918  Thyroid hormone synthesis
ocu04921  Oxytocin signaling pathway
ocu04923  Regulation of lipolysis in adipocytes
ocu04925  Aldosterone synthesis and secretion
ocu04926  Relaxin signaling pathway
ocu04927  Cortisol synthesis and secretion
ocu04928  Parathyroid hormone synthesis, secretion and action
ocu04934  Cushing syndrome
ocu04935  Growth hormone synthesis, secretion and action
ocu04970  Salivary secretion
ocu04971  Gastric acid secretion
ocu04972  Pancreatic secretion
ocu04976  Bile secretion
ocu05032  Morphine addiction
ocu05163  Human cytomegalovirus infection
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05207  Chemical carcinogenesis - receptor activation
ocu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100346742
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100346742
   04072 Phospholipase D signaling pathway
    100346742
   04024 cAMP signaling pathway
    100346742
   04022 cGMP-PKG signaling pathway
    100346742
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100346742
   04081 Hormone signaling
    100346742
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100346742
   04062 Chemokine signaling pathway
    100346742
  09152 Endocrine system
   04911 Insulin secretion
    100346742
   04923 Regulation of lipolysis in adipocytes
    100346742
   04913 Ovarian steroidogenesis
    100346742
   04915 Estrogen signaling pathway
    100346742
   04921 Oxytocin signaling pathway
    100346742
   04926 Relaxin signaling pathway
    100346742
   04935 Growth hormone synthesis, secretion and action
    100346742
   04918 Thyroid hormone synthesis
    100346742
   04928 Parathyroid hormone synthesis, secretion and action
    100346742
   04925 Aldosterone synthesis and secretion
    100346742
   04927 Cortisol synthesis and secretion
    100346742
  09154 Digestive system
   04970 Salivary secretion
    100346742
   04971 Gastric acid secretion
    100346742
   04972 Pancreatic secretion
    100346742
   04976 Bile secretion
    100346742
  09156 Nervous system
   04724 Glutamatergic synapse
    100346742
   04727 GABAergic synapse
    100346742
   04725 Cholinergic synapse
    100346742
   04723 Retrograde endocannabinoid signaling
    100346742
  09157 Sensory system
   04742 Taste transduction
    100346742
   04750 Inflammatory mediator regulation of TRP channels
    100346742
  09149 Aging
   04211 Longevity regulating pathway
    100346742
   04213 Longevity regulating pathway - multiple species
    100346742
  09159 Environmental adaptation
   04713 Circadian entrainment
    100346742
   04714 Thermogenesis
    100346742
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100346742
   05207 Chemical carcinogenesis - receptor activation
    100346742
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100346742
   05163 Human cytomegalovirus infection
    100346742
  09165 Substance dependence
   05032 Morphine addiction
    100346742
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100346742
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100346742
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100346742
Enzymes [BR:ocu01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100346742
SSDB
Motif
Pfam: Guanylate_cyc Adcy_cons_dom AC_N CD52
Other DBs
NCBI-GeneID: 100346742
NCBI-ProteinID: XP_008267668
Ensembl: ENSOCUG00000002958
LinkDB
Position
17:complement(45262524..45278744)
AA seq 1086 aa
MARLFSPRPPPSDDLFYETYYSLSQQYPLLLLLLGIVLCALVALLGVAWASGRELISDPS
FLSTVLCALGGFSLLLGLASREQRLQRWTRALSGLVWAALLALGHGFLFTGGVVSAWNQV
SFFLFVIFTAYAMLPLGMRDAVAAGLASSLSHLLVLGLYLGPQPDSQPALLPQLAANAVL
FVCGNAVGAYHKALMERALRATFREALSSLQSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPVSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGHELLRPSLLMT
RYLESWGAAKPFAHLSHIDSPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDELDTGDA
KFFQVIEQLNSQKQWRQSKDFSPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNF
IIQMLVTDRPPALAITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSGLVATR
PGLRVALGTATILLVFIMAITSLFFLPASLDCPPWAPNVSSIAFNLSWQLPGSLPLLSVP
YSMHCCVLGSLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYVGPLD
SRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTR
LLLENVLPAHVAPQFIGQKRRNEDLYHQSYECVCVLFASIPDFKEFYSESNINHEGLECL
RLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQVQQQAHCQDAER
SCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTV
NVASRMESTGVLGKIQVTEETAQALQSLGYTCCIRGIIKVKGKGQLRTYFLNTDLTRTGP
PSATLG
NT seq 3261 nt   +upstreamnt  +downstreamnt
atggcgcgcctcttcagcccccggccgcctcccagcgacgacctcttttacgagacctac
tacagcttgagccaacagtacccgctactgctgctgctgctggggatcgtgctgtgcgcg
ctcgtggcgctgctcggcgtcgcctgggccagcggcagggagctgatctcagacccgagc
ttcctaagcaccgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctggcttcc
cgcgagcagcgacttcagcgctggacgcgcgccctgtccggcctcgtgtgggccgcgctg
ctagcgctcggccacggcttcctgttcacagggggcgtggtgagcgcctggaaccaggtg
tcctttttcctcttcgtcatcttcacggcgtatgccatgctgcccttggggatgcgggac
gcggtcgctgcaggcctggcctcttcactctcgcacctgctggtcctggggctgtacctt
gggccacagcctgattcgcagccggcgctgctgccgcagcttgcagccaacgcagtgctg
ttcgtgtgtgggaacgcggtgggggcgtaccacaaagcgctgatggagcgtgccctgcgc
gccaccttccgcgaggcgctcagctccctgcagtcgcgccggcggctggacaccgagaag
aagcaccaggaacacctgctgttgtccatccttcctgcctacctggccagggagatgaag
gcagagatcatggctcggctgcaggctggacaggggtcccggccagagagcaccaacaac
ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg
ggcttcaccaggctggccagcgagtgctcccccaaggagctggtgctcatgctcaacgag
ctctttggaaaattcgaccagatcgccaaggagcacgaatgcatgcggatcaagatccta
ggggactgctactactgtgtctccgggcttccagtctccctgccagaccatgccatcaac
tgcgtacgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggt
gtagatatcaacatgcgtgtgggcgtgcactcgggcagcgtgctctgcggagtcatcggc
ctgcagaagtggcagtacgatgtctggtcccatgacgtcacactggccaaccacatggag
gcaggcggcgtgccaggacgagtgcacatcacgggggccacgctggctctgctggccggg
gcttacgcagtggaggacgcagccatggaacaccgggacccgtaccttcgagagctaggg
gagccgacctacctggtcattgatccccgggccgaggaggaggacgagaagggcacagca
ggagggctgctgtcctctctcgagggccacgagctgctgcgtccgtctctgctgatgacc
cgctacctggagtcgtggggtgcagccaagccttttgcccacctgagccacatagacagc
cctgtgtccacctccacccctctcccggagaaggccttggcttccttcagcccccagtgg
agcctggaccggagccgtaccccccggggcctagacgatgagctggacaccggggatgcc
aagtttttccaggtcatcgaacagctcaactctcagaaacaatggaggcagtcgaaggac
ttcagcccactgacgctctacttcagagagaaggagatggagaaggagtaccgtctctcc
gcactccctgccttcaagtactatgcagcctgcaccttcctggtttttctctccaacttc
atcatccagatgctggtgacagacaggcccccagctctggccatcacctacagcatcacc
ttcctcctcttcttcctcctgctcttcgtctgcttctcagagcacctgacgaagtgtgtc
ctgaagggccccaagatgctgcactggctgcccacactgtccggcctggtagccacacgc
cctggactgcgagtggccctgggcactgccaccatcctcctcgtcttcatcatggccatt
accagcctgttcttcctaccagcatcgctggactgtccaccctgggctcccaatgtgtcc
tccattgctttcaacctctcctggcagctccctgggtccctgcccctcctcagtgtccca
tactccatgcactgctgcgtgctgggctccctgtcctgctccctctttctgcacatgagc
ttcgaactcaagctgctgctgctgctgctctggctcgtggcctcctgctccctcttcctg
cactcccacgcctggctgtccgactgcctcatcgcccgcctctacgtgggacccttggac
tccaggccgggcgtgctgaaggagcccaagctgatgggagccatctccttcttcatcttc
ttcttcaccctccttgtcctggctcgacagaatgagtattactgccgcctggacttcctg
tggaagaagaagctgaggcaagagcgcgaggagacagagatgatggagaatctgacccgg
ctgctcttggagaacgtgctccctgcacacgtggccccccagttcattggccagaaacgg
cgcaacgaggacctctaccaccagtcctacgagtgtgtttgtgtcctcttcgcctccatc
ccagactttaaggagttctactcggaatccaacatcaaccacgaagggctcgagtgtttg
cggctactcaatgagatcattgctgatttcgatgagctgctctccaagcccaagttcagc
ggggtggagaagatcaaaaccatcggcagcacctacatggcagccacaggcttaaacgcc
acctctggccaggatgcccaacaggtccagcaacaggcccactgccaggatgctgagcga
agctgcagccaccttggcaccatggtggaatttgcagtggccctggggtccaagctagac
gtcatcaacaagcactcgttcaacaacttccgcctgcgtgtggggctgaaccacggacca
gtagtggctggagtcattggggcccagaagccacaatatgacatctggggcaacacggtg
aatgtggccagccgcatggagagcaccggagtcctgggcaaaatccaggtgactgaggag
acagcccaggccctgcagtcgctgggctacacctgctgcattcggggcatcatcaaggtc
aaaggcaaagggcagctgcgcacctacttcctgaacacggacttgacgcgaactgggcct
ccctcagccaccctgggctga

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