KEGG   Oryctolagus cuniculus (rabbit): 100346929
Entry
100346929         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04014  Ras signaling pathway
ocu04024  cAMP signaling pathway
ocu04068  FoxO signaling pathway
ocu04071  Sphingolipid signaling pathway
ocu04137  Mitophagy - animal
ocu04140  Autophagy - animal
ocu04141  Protein processing in endoplasmic reticulum
ocu04210  Apoptosis
ocu04215  Apoptosis - multiple species
ocu04217  Necroptosis
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04510  Focal adhesion
ocu04530  Tight junction
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04722  Neurotrophin signaling pathway
ocu04723  Retrograde endocannabinoid signaling
ocu04728  Dopaminergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04910  Insulin signaling pathway
ocu04912  GnRH signaling pathway
ocu04914  Progesterone-mediated oocyte maturation
ocu04917  Prolactin signaling pathway
ocu04920  Adipocytokine signaling pathway
ocu04926  Relaxin signaling pathway
ocu04930  Type II diabetes mellitus
ocu04931  Insulin resistance
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05010  Alzheimer disease
ocu05012  Parkinson disease
ocu05016  Huntington disease
ocu05017  Spinocerebellar ataxia
ocu05020  Prion disease
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05142  Chagas disease
ocu05145  Toxoplasmosis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05162  Measles
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05200  Pathways in cancer
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05231  Choline metabolism in cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100346929
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100346929
   04012 ErbB signaling pathway
    100346929
   04014 Ras signaling pathway
    100346929
   04310 Wnt signaling pathway
    100346929
   04668 TNF signaling pathway
    100346929
   04068 FoxO signaling pathway
    100346929
   04071 Sphingolipid signaling pathway
    100346929
   04024 cAMP signaling pathway
    100346929
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100346929
   04137 Mitophagy - animal
    100346929
  09143 Cell growth and death
   04210 Apoptosis
    100346929
   04215 Apoptosis - multiple species
    100346929
   04217 Necroptosis
    100346929
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100346929
   04530 Tight junction
    100346929
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100346929
   04621 NOD-like receptor signaling pathway
    100346929
   04622 RIG-I-like receptor signaling pathway
    100346929
   04625 C-type lectin receptor signaling pathway
    100346929
   04660 T cell receptor signaling pathway
    100346929
   04658 Th1 and Th2 cell differentiation
    100346929
   04659 Th17 cell differentiation
    100346929
   04657 IL-17 signaling pathway
    100346929
   04664 Fc epsilon RI signaling pathway
    100346929
  09152 Endocrine system
   04910 Insulin signaling pathway
    100346929
   04920 Adipocytokine signaling pathway
    100346929
   04912 GnRH signaling pathway
    100346929
   04914 Progesterone-mediated oocyte maturation
    100346929
   04917 Prolactin signaling pathway
    100346929
   04926 Relaxin signaling pathway
    100346929
   04935 Growth hormone synthesis, secretion and action
    100346929
  09156 Nervous system
   04728 Dopaminergic synapse
    100346929
   04723 Retrograde endocannabinoid signaling
    100346929
   04722 Neurotrophin signaling pathway
    100346929
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100346929
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100346929
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100346929
   05208 Chemical carcinogenesis - reactive oxygen species
    100346929
   05231 Choline metabolism in cancer
    100346929
  09162 Cancer: specific types
   05210 Colorectal cancer
    100346929
   05212 Pancreatic cancer
    100346929
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100346929
   05170 Human immunodeficiency virus 1 infection
    100346929
   05161 Hepatitis B
    100346929
   05171 Coronavirus disease - COVID-19
    100346929
   05162 Measles
    100346929
   05167 Kaposi sarcoma-associated herpesvirus infection
    100346929
   05169 Epstein-Barr virus infection
    100346929
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100346929
   05135 Yersinia infection
    100346929
   05133 Pertussis
    100346929
   05152 Tuberculosis
    100346929
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100346929
   05142 Chagas disease
    100346929
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100346929
   05012 Parkinson disease
    100346929
   05016 Huntington disease
    100346929
   05017 Spinocerebellar ataxia
    100346929
   05020 Prion disease
    100346929
   05022 Pathways of neurodegeneration - multiple diseases
    100346929
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100346929
   05418 Fluid shear stress and atherosclerosis
    100346929
   05415 Diabetic cardiomyopathy
    100346929
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100346929
   04936 Alcoholic liver disease
    100346929
   04932 Non-alcoholic fatty liver disease
    100346929
   04931 Insulin resistance
    100346929
   04933 AGE-RAGE signaling pathway in diabetic complications
    100346929
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100346929
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100346929
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100346929
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100346929
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 100346929
NCBI-ProteinID: XP_051693488
Ensembl: ENSOCUG00000002873
UniProt: G1TPJ7
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFERLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVISGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAPA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagatcggagattctacattc
acagtcctgaagcgatatcagaatctaaaacctataggttctggagctcaaggaatagtc
tgtgcagcttatgatgccattcttgaaagaaatgttgccatcaagaagctaagccggccg
tttcagaatcaaacgcatgctaagagggcctacagagagctggttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatctctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcgaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactccgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaaaatccttgactttggactggccaggactgcaggaacaagcttt
atgatgacgccttatgtggtgactcgctactacagagcgcctgaggtcatcctgggcatg
ggctacaaggagaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
ctgggaacaccatgtcctgagttcatgaagaaactgcaaccaacagtaaggacttacgtg
gaaaacagacctaagtatgccggatatagctttgagaggctcttccccgatgtgcttttc
ccagctgactcggaacacaacaagcttaaagccagtcaggcaagggatttgctctctaaa
atgctggtgatagatgcatctaagaggatctctgtagacgaagctctccagcacccatac
atcaatgtctggtacgatccctctgaagcagaagccccaccaccaaagattcctgacaaa
cagttagacgaaagggaacacacgatagaagaatggaaagaattgatatacaaggaagtg
atggatttggaagaaagaaccaagaatggagttatacgagggcagccctctcctttaggt
gcagcagtgatcagtggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagacccgactttggcctcggatacagacagcagtctggaagccccagct
gggcctctgggctgctgtagatga

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