Oryctolagus cuniculus (rabbit): 100349438 Help Entry 100349438         CDS       T03373                                  Name (RefSeq) neurofibromin isoform X4   KO K08052   neurofibromin 1 Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu01521   EGFR tyrosine kinase inhibitor resistance ocu04010   MAPK signaling pathway ocu04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100349438    04014 Ras signaling pathway     100349438  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100349438 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 MIF4G_like_2 Motif Other DBs NCBI-GeneID:  100349438 NCBI-ProteinID:  XP_002718982 Ensembl:  ENSOCUG00000008567 UniProt:  G1SVG6 LinkDB All DBs Position 19:18259102..18564087 Genome browser AA seq 2841 aa AA seqDB search MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTERNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN SALDWWPKIDAVYCHSVELRNMFGETLHKALQGCGAHPAIRMAPSLTFKEKVTSLKFKEK PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL REILICRNKFLLKNKQADRSSCHFLYLYGVGCDVPSSGNTSQMSMDHEELLRSCAPGASL RKGRGNSSVDGAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD IRCRVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTPGNTEAWE DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSDGNADTPVSKFMDRL LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS FEVDPTRLEPSESLEENQRNLLQMTERFFHAITSSCSEFPPQLRSVCHCLYQATCHSLLN KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSF ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY VYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLQFSEETKQVLRLSLTEFSL PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRGRFSLKHR QSLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGHLTATYPTVGQTSPRA RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGMTTPPKMRRVAETDYE METPRISSAQQHPHLCKVSMSESNALLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRI LYAYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQY QTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTP TSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGLDKENVELSPTTGHCNSGRTRHGSA SQVQKQRSAGSFKRNSIKKIV NT seq 8526 nt NT seq  +upstreamnt  +downstreamnt atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag cttccaataaaaacaggacagcagaacacacataccaaagtcagtactgaacgcaacaag gaatgtctgatcaatatttccaagtacaagttttctttggttattagtggcctcactact atcttaaagaatgttaataatatgagaatatttggagaagctgctgaaaaaaatttgtat ctttctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggat acaatgagattagatgagacgatgctggttaaacagttgctgccagaaatctgccatttt cttcacacctgtcgtgaaggaaaccagcatgcagctgaacttcggaattctgcctctggg gttttattttctctcagctgcaacaacttcaatgcagtctttagtcgaatttcaaccagg ttacaagaattgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta caatatatcaatgtggattgtgcaaaattaaaacgacttctgaaggaaacagcatttaaa tttaaagctttaaagaaagttgcacagttagctgttataaatagcttggaaaaggcattt tggaattgggtagaaaattatccagatgaatttacaaagctgtaccagattccacagact gatatggctgagtgcgcagaaaagctgtttgacttggtggatggctttgctgaaagcacc aaacgtaaagccgcagtttggccattacaaatcattcttcttatcttgtgtccagaaata atccaggatatatccaaggatgtggttgatgaaaacaacatgaataagaaattgtttctg gacagtttacgaaaagcacttgctggccacggaggaagcaggcagctaacagaaagtgct gccattgcctgtgtcaaactgtgtaaagcaagtacttatatcaactgggaagataactct gtcattttcctactggtccagtccatggtggttgatcttaagaacttgctttttaatcca agtaaaccgttctccagaggcagtcagcctgcggatgtggatctgatgattgactgcctt gtttcttgctttcgtataagccctcacaacaaccaacactttaagatctgcctggctcag aattcaccttctacatttcactatgtgctggtaaattcactgcatcgaatcatcaccaat tctgcactggattggtggcctaagattgatgctgtgtattgccactcagttgaacttcga aatatgtttggtgaaacccttcataaagcacttcagggctgcggagcacacccagcaata cgaatggcaccgagtcttacttttaaagaaaaagtaacaagccttaaatttaaagaaaaa cctacagacctggagacaagaagctataaatatctgctcttgtctatggtgaaactgatt catgcggatccaaagctcttgctttgtaatccaaggaaacaggggcctgagacccaaggc agtacggcagaattaattacaggactagtgcaactggtccctcagtcacacatgccagag attgctcaggaagcgatggaggctctgttggttcttcatcagttagatagcattgatttg tggaatcccgatgctcctgtggaaactttttgggagattagctcacagatgcttttttac atctgcaagaaattaactagtcatcagatgcttagtagcacagaaattctcaagtggttg cgggaaattctgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagt tcctgtcactttctttacctatatggggtaggatgtgatgtgccttctagtgggaatacc agtcagatgtccatggatcacgaagagctgctgcggtcctgtgctccgggagcctctctc cggaaggggagaggaaactcctctgtggatggtgctgcaggttgcagtggaaccccaccc atatgccgacaagcccagaccaaactggaagtggctctgtacatgtttctgtggagccca gacactgaagctgtcctggttgccatgtcctgtttccgccacctctgcgaggaagcagat atccggtgtagggtagatgaagtgtcggtgcacaacttcttgcccaactataacacgttc atggagttcgcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaaga gtgatggcactgctacggcgcatcgagcatcccactccagggaacacagaggcttgggaa gatacacatgcaaaatgggagcaagctacaaaattaatccttaactatccaaaagccaaa atggaagatggccaggctgccgagagccttcacaagaccattgttaagaggcgaatgtcc catgtgagtggaggaggatccatagatttgtctgacacagactccctgcaggagtggatc aacatgactggcttcctttgtgctcttgggggtgtgtgcctgcagcagaggagcaattcc ggcctggcgacctatagcccacccatgggccccgtcagtgaacgaaagggttccatgatt tcagtgatgtcttcagatggaaatgcagacacacctgttagcaaatttatggacaggctg ctctccttgatggtgtgtaaccatgagaaagtgggacttcagatacggaccaacgttaag gatctagtgggtctagagttgagtcctgctctttatccaatgctgtttaacaaattgaag aacaccatcagcaagttttttgattcccaaggacaggttttattgactgacaccaatact cagtttgtagagcaaaccatagctataatgaagaacttactagataatcataccgaaggc agctctgaacatctggggcaagctagcattgaaacgatgatgttaaatctggtcagatat gttcgtgtgcttggaaatatggtccatgcaattcaaataaaaacaaagctttgtcagtta gttgaagtcatgatggcaagaagagatgacctctcattttgtcaagagatgaaatttagg aataagatggtagaatacctgacagactgggttatgggaacatcaaaccaagcagcagat gatgatgtaaaatgtcttacaagagatttggaccaggcaagcatggaagcagtagtttca ctcctggctggtcttccgctgcagcctgaggaaggagatggtgtggaactgatggaagcc aaatcacagttatttcttaagtacttcacgttatttatgaaccttctgaatgactgtagt gaagttgaagatgaaaatgcacagacaggtggcaggaagcgtggcatgtctcggaggctg gcatcactgaggcactgtacagttcttgcgatgtcgaacttgctcaatgctaatgtggac agtggcctcatgcactccataggtttaggttatcacaaggatctccagacgagagctaca tttatggaagttctgacaaaaatccttcaacaaggcacagagtttgatacccttgcagaa acggtgctggcagatcggtttgagagactagtggagttggtcaccatgatgggtgatcag ggagagctccccatagctatggctctggccaatgtggtcccttgttcgcagtgggatgaa ctagctcgagttctggttaccctatttgattctcggcatttgctctaccaactgctctgg aacatgttttcgaaggaagtagaattagcagactctatgcagactctcttccgaggcaac agcttggccagcaaaataatgacattctgtttcaaggtatatggtgctacctacctacaa aaactcctggatcctttattacgaattgttattacatcctctgattggcaacatgtcagc tttgaagtggatcctaccagactggaaccgtcagagagcctcgaggagaaccagcggaac ctccttcagatgacggagaggttcttccacgccatcaccagctcctgctccgagttcccc cctcagcttcgcagtgtgtgccactgcctgtaccaggcaacttgccactccctactgaac aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgttttcct cagaacagcatcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccatt gtctcaccgtatgaagcaggcattttagataaaaagccaccacctagaatcgaaaggggc ttgaagttaatgtcaaagatacttcagagtattgccaatcatgttctcttcacaaaagag gagcatatgaggccttttaatgattttgtgaaaagcaactttgatgcagctcgaaggttt ttccttgatatagcgtcagattgccctacaagtgatgcagtaaatcatagtctttccttc atcagtgatggcaatgtgcttgctttacatcgtcttctttggaacaatcaagagaaaatt ggccagtatctttccagcaatagggatcataaagctgttggaagacgaccttttgataaa atggcaaccctgctcgcatacctgggccctccagagcacaagcctgtggcagacacgcac tggtccagccttaacctcaccagctccaagtttgaggaatttatgacaaggcatcaggta catgagaaagaagagttcaaggctttgaaaacattaagtattttctaccaagctgggact tccaaagctgggaatcctattttttattatgttgcacggaggttcaaaactggccaaatc aatggtgatctgctgatataccacgtcttgctaactttaaagccatattatgcaaagcca tatgaaattgtagtggaccttacgcatactgggcccagcaatcgctttaaaacagacttt ctctccaagtggtttgttgtttttcctggctttgcttatgacaacgtctctgcagtctat gtctacaactgtaactcctgggtcagggagtacaccaagtaccatgagcggctgctgact ggtctcaaaggtagtaaaagactcatcttcatagattgtcctgggaaactggctgagcac atagagcacgaacaacagaaactgcctgctgccaccttggctttagaagaggacctaaag gtgttccacaatgctctcaagctagctcacaaagacaccaaagtttccattaaggttggt tctactgctgttcaagtaacctcagctgagagaacaaaagtcctagggcagtcagttttt ctaaatgatatctattatgcctcggaaattgaagagatctgcctggtggatgagaaccag ttcaccttaaccattgcaaaccagggcacaccactcaccttcatgcatcaggagtgtgaa gccatcgtccagtctatcattcatatccggacacgctgggagctgtcacagcctgactcc atcccccagcacaccaagattcggccaaaagacgtacctgggacactgcttaatattgca ttacttaatttgggcagttcagaccctagtttacggtcagctgcctataatcttctctgt gccttaacttgtacttttaatttaaaaatcgagggccagttactagagacatcaggttta tgtatccctgccaacaacactctctttattgtctcgattagtaagacactggcagccaac gagccacacctcacgttagaatttttggaagagtgtatttctggatttagcaaatctagt attgagttgaagcacctctgtttggaatatatgactccgtggctgtccaatctagtccgt ttttgcaagcataacgatgatgccaaacgacaaagagtgactgctattcttgataagctg ataacaatgaccataaatgaaaaacagatgtacccgtctattcaagcaaaaatatggggg agccttgggcagattacagatctgcttgatgttgtactagacagcttcatcaaaaccagt gcaacaggtggcttgggatccatcaaagctgaggtgatggcagatactgctgtagctttg gcctctggaaatgtgaaattggtttcaagcaaggttattggacggatgtgcaaaataatt gataagacgtgcttgtctccaactccgactttggagcagcatctgatgtgggatgacatc gccatcttagcacgctacatgctgatgctgtccttcaacaactccctcgatgtggcagct catctcccctacctcttccacgtcgtgacgttcttagtggccactggcccactctcgctg agagcttccacacatgggctggtcatcaatatcatccactctctgtgcacttgttcacag cttcagtttagtgaagagaccaagcaagttttgagactcagtctgacagagttctcattg ccaaaattttacttgctgtttggcattagcaaagtcaagtcagccgcagtcattgccttc cgttccagttaccgggacaggtcattctctcctggctcctacgagagggagacttttgct ttgacatctttggaaacagtcacagaagccttgttggagatcatggaggcatgtatgaga gacattccaacatgcaagtggctggaccagtggacagaactagcgcaaagatttgcattc caatataatccatccctacaaccaagagctcttgttgtctttggctgtattagcaaacga gtgtctcatggccagataaagcaaattatccgtattcttagcaaggcacttgagagttgc ttaaaaggacctgatacttacaacagtcaagttctgatagaagctacagtaatagcacta accaaattacagccacttcttaataaggactcccctctacacaaagccctcttctgggta gctgtggccgtgctgcagctcgatgaggtcaacttgtattcagcaggcactgctcttctt gaacaaaacttgcacaccctggatagtctccggatattcaatgacaagagtccagaagaa gtatttatggcaatccggaatcctctggaatggcactgcaagcaaatggatcattttgtt ggactcaatttcaactccaactttaattttgcactggttggacacctcttaaaagggtac agacatccttcacctgctattgttgcaagaacagtcagaattttgcatacactactaact ttggttaacaaacacagaaactgtgacaagtttgaggtgaatacgcagagtgtggcttac ttagcagctttactcacagtgtctgaagaggttcgaggtcgtttcagcttaaaacataga cagtcacttcttcttactgatatttcaatggaaaatgttcctatggacacatatcccatt catcatggtgatcccagctacaggacactaaaggagaatcagccatggtcctctcccaaa ggttctgaagggcatctgacagccacctatccaactgtgggacagaccagtccccgagcc aggaaatccatgagcttggatatggggcagccttctcaggctaacactaagaaattgctt ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa atggaatcagggatgacaacaccccccaaaatgaggagagtagcagagactgattatgaa atggaaactccaaggatttcctccgcacagcagcacccgcatttatgtaaggtttccatg tcggaatcgaatgctctcttggatgaagaagtgctgactgatccgaagatacaagcgctc cttcttaccgttctagctactctggtaaaatataccacggatgagtttgatcaacgaatt ctttatgcgtacttagcagaggccagtgtggtattccccaaagtttttcctgttgtgcac aatttgctggactctaagatcaacaccctgttgtcattgtgccaagacccaaatctgtta aatccaatccatggaatcgtgcagagtgtggtgtatcatgaagaatcccctccacagtac cagacgtcttacctgcaaagttttggctttaatggcttatggcggtttgcaggacccttt tcaaagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttg attgacacgtacttgcctggaattgatgaagaagccagtgaggagtccctcctgacaccc acatctccttaccctcctgcactgcagagccagcttagtatcactgccaaccttaacctc tctaattccatgacctcacttgcaacttcccagcattccccaggactggacaaggagaac gtggaactctcccccaccaccggccactgtaacagtggacgcacgcgccacggatccgca agccaagtgcagaagcagagaagcgctggcagtttcaaacggaatagcatcaagaagatc gtgtga

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