Oryctolagus cuniculus (rabbit): 100351427
Help
Entry
100351427 CDS
T03373
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100351427
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ocu03032
]
100351427
03036 Chromosome and associated proteins [BR:
ocu03036
]
100351427
Enzymes [BR:
ocu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100351427
DNA replication proteins [BR:
ocu03032
]
Eukaryotic type
DNA Topoisomerases
100351427
Chromosome and associated proteins [BR:
ocu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100351427
Centrosome formation proteins
Centriole proteins
100351427
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
100351427
NCBI-ProteinID:
XP_051674464
Ensembl:
ENSOCUG00000000717
LinkDB
All DBs
Position
14:complement(13317530..13387849)
Genome browser
AA seq
1623 aa
AA seq
DB search
MAKSGGGGGAGAGAGGGALTWVTLFDQNNAAKKEESETASKNDTSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQLMWVYDEEVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKISIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLAKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
DGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEA
QEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK
KGDLDTTAVKVEFDEEFSGTPIEGTGEEALTQSAPVNKGPKPKREKKEPGTRVRKTPTTS
GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPIINDGEDEFVPSDGLDKDEYTFSPGKSKTTPEKSSHDKKSQ
DFGSLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTAAAKKGKPTSD
TTPKPKRTPKQKKVVETVNSDSDSEFGIPKKSTAPKGKGRGAKKRKASGSENEGDYNPGR
KPSKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFA
MFN
NT seq
4872 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggcggcggcggcggcgctggagccggcgcgggcggcggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaagc
aaaaatgatacttccaagaagttgtctgttgagagagtgtatcagaagaagacacaactt
gaacatattctccttcgtcctgacacatacattgggtcagtggagccattgacacagtta
atgtgggtgtatgatgaagaagtaggaatgaattgcagagaggttacctttgtgccaggt
ttatataagatctttgatgaaattttggttaatgctgctgacaataaacagagggataag
aatatgacctgtattaaaatttcaattgacccagaatctaacattataagcatttggaat
aatgggaaaggcattccagtagtagaacacaaagtagagaaagtgtatgttcctgcttta
atttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgcaatggttatggtgcaaaactttgtaatatttttagtacaaagtttacagtagaa
acagcttgcaaagaatacaaacacagttttaagcagacatggatgaataatatgatgaag
acctctgaagccaaaattaagcattttgatggtgaagattacacatgtataacattccaa
ccagatctggccaaatttaagatggaaaaacttgacaaggatattgtggctctcatgacc
agaagagcgtatgatttggctggttcatgtaaaggggtcaaagtcatgtttaatggaaag
aaattaccagtaaatggatttcgaagttatgtggatctttatgtgaaagacaaattagat
gaaactggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgc
ctcacactgagtgaaaaaggcttccagcaaatcagctttgtaaatagtattgcaacgaca
aaaggtggacggcacgtagactatgtagtagatcaagttgttggtaaactgattgaagtg
gttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtgaaaaaccacata
tgggtttttattaattgccttattgaaaatccaacttttgattctcaaactaaggaaaac
atgactctgcaacccaaaagttttggatccaaatgccaactgtcagaaaaattttttaaa
gcagcttctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaagctcag
actcagctgaacaagaagtgttcatcagtaaaatatagtaaaatcaaaggtattcccaaa
ctggatgatgctaatgatgctggaggcaaacattccctggaatgtacactgatattaaca
gagggagactctgccaaatcactggccgtgtctggattaggtgtgattgggcgagacaga
tacggagtttttccactcaggggtaaaattcttaatgtacgggaagcttctcataaacag
atcatggaaaatgcagaaataaataatattattaaaatagttggtctacagtacaaaaaa
agttatgatgatgcagaatctctgaaaacattacgttatggaaagattatgattatgact
gatcaggatcaagatggttctcatatcaaaggcctgcttattaatttcattcatcacaat
tggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggca
agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaaggattgggtaccagtaca
gctaaagaagcaaaagaatattttgctgatatggaaaggcatcgcatcttgtttagatat
gctggccctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac
agaaaagaatggttaacaaattttatggaagatcggaggcagcgtaggttacatggctta
ccagagcaatttttatatggtacagcaacaaaacatttgacttacaatgatttcatcaac
aaggaattgattctgttctcaaactcagacaatgagagatctataccatctcttgttgat
ggtttcaaacctggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgt
gaagtaaaagttgcccagttggctggatctgttgctgagatgtctgcctatcatcatgga
gaacaagcgttgatgatgacaattgtgaacttggctcagaactttgtgggaagtaacaac
attaacttgcttcagcctattggtcagtttgggactcgacttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagattactttttcctgct
gtggatgacaacctgcttaagtttctttatgatgataatcaacgtgtagagcctgagtgg
tatattcccataattcccatggttttaataaatggtgctgaaggcattggtactggatgg
gcttgtaaactaccaaattatgatgccagggaaatcgtgaacaatgtcaggcgaatgcta
gatggtttggatcctcatcccatgcttccaaactataagaactttaaaggcacaatccaa
gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtggttgatagaaacaca
gtagaaattacagagcttccagtcagaacttggacacaggtatacaaagaacaagttttg
gaacctatgctaaatgggaccgacaaaacaccagcattaatttctgattataaagaatat
catactgatacaactgtgaaatttgtggtgaaaatgacagaggagaaactagcacaagca
gaagctgctggattacataaagtttttaagcttcaaactactctgacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattctgaaa
gaattctttgatttacggttaagttattatggtttacgaaaggagtggcttgtaggaatg
ttgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggcccc
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa
ctgattaaacagagagatacaaaaggacgagaggtcaatgatcttaaaagaaaatctcct
tcagacctttggaaagaagatttagcagcatttgttgaagaactggataaagtggaagct
caagaacgagaagatatcctggctggaatgtctggaaaagcaataaaaggtaaagttggc
aaacctaaggtgaagaagcttcaattggaagagacaatgccctcaccttatggaaggaga
ataattccagaaattactgccatgaaggcagatgccagcaaaaagttactgaagaagaag
aagggtgatcttgataccacagcagtaaaagtagagtttgatgaagaattcagtggaaca
ccaatagaaggtacaggagaagaggcactgacacaatcagcacctgtaaacaaaggcccc
aagcccaaaagggagaaaaaagagcctggtaccagggtgagaaaaacacctacaacatct
ggtaaacccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag
tcagagagtgatttggaagaaacagaacctgtggttattccaagagattctttgcttagg
agagcagctgctgaaagacctaaatacacatttgatttctcagaagaagaggatgatgat
gctgatgatgatgatgacaataatgacttagaggagctgaaagttaaagcatctcccata
ataaatgatggggaagatgaatttgttccttcagatggcctggataaagatgaatataca
ttttcaccaggcaaatcaaaaactactccagaaaaatcttcacatgacaaaaaaagtcag
gatttcgggagtctcttctcatttccttcatactctcaaaagtcagaagatgattcagct
aaatttgacagtaatgaagaagattctgcttctgttttttccccgtcgtttggtttgaaa
caaacagataaagttccaagtaaaacagcagctgccaaaaagggaaaaccaacttcagat
acaacccctaagcccaagagaacacccaaacagaagaaagtagtagagactgtaaactct
gactcagattcagaatttggcattccaaagaagagtacagcaccaaaaggtaaaggccga
ggggcaaagaaaaggaaagcttctggttccgaaaatgaaggtgattataaccctggcagg
aaaccatccaaaaccacaagcaagaaaccgaagaaaacatcttttgatcaggattcagat
gtggacatcttcccctcagacttcacttctgaaccaccttctctgccacgaactggccga
gctagaaaagaagtaaaatattttgcagaatctgatgaagaagaagatgttgattttgca
atgtttaattaa
DBGET
integrated database retrieval system
