Oryctolagus cuniculus (rabbit): 100353481
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Entry
100353481 CDS
T03373
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00020
Citrate cycle (TCA cycle)
ocu00620
Pyruvate metabolism
ocu01100
Metabolic pathways
ocu01200
Carbon metabolism
ocu04934
Cushing syndrome
ocu05200
Pathways in cancer
ocu05211
Renal cell carcinoma
Module
ocu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ocu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100353481
00620 Pyruvate metabolism
100353481
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100353481
09162 Cancer: specific types
05211 Renal cell carcinoma
100353481
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100353481
Enzymes [BR:
ocu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
100353481
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
100353481
NCBI-ProteinID:
XP_002722110
UniProt:
G1TUE0
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All DBs
Position
14:817106..818730
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AA seq
508 aa
AA seq
DB search
MYRALRVFARSGHLARAPASASAPGLSGAAVLPVWLPNAARMASQNSFRTEYDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMK
AADEVAEGKLNDHFPLVIWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALEAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYAMARIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIENDVRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDASVSFTENCVLGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KETAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgagcactccgggtcttcgcgcggtcaggccaccttgcgcgagctccagcctcc
gcctcggctccgggcttgagtggcgctgccgtcctcccagtctggcttccgaacgccgct
cgaatggcaagccaaaattccttcaggacagaatatgatacctttggggaactcaaggtc
ccaaatgataagtattatggtgcccagactgtgagatctacaatgaacttcaagattgga
ggtgtgacggaacgcatgccaattccagttattaaagcttttggcatcttgaagcgagca
gctgctgaagtaaaccaggattatggtcttgatccaaagatcgccaatgcaataatgaag
gcagcagatgaggtagctgaaggtaaattaaatgatcattttcctctcgtgatatggcag
actggatcgggaacccagacaaatatgaatgtaaatgaagtcattagcaacagagcaatt
gagatgttgggaggtgaacttggcagtaagaaacctgtgcatcccaatgatcatgttaat
aaaagccagagttcaaatgatactttccccacagcaatgcacattgctgctgcaatagaa
gttcatgaagtactcttaccaggactccagaagttacatgatgctctggaagcaaaatcc
aaagagttcgctcagatcatcaaaattggacgaactcatactcaggatgctgttccactt
actcttggtcaggaattcagtggttatgttcaacaagtgaaatatgcaatggcgagaata
aaagctgccatgccaagaatctatgagctcgcagctggaggcactgctgttggtactggc
ttaaatactagaattggctttgcagaaaaggttgctgcgaaggtggctgccctcacaggc
ttgccttttgtcactgctccaaataaatttgaagctctggctgctcatgatgctctggtt
gagctcagtggagccatgaacacgactgcttgcagtctgatgaagatagaaaatgatgtt
cgttttctgggttctggccctcggtcaggcctgggagaattgatcttgcctgaaaatgaa
ccgggaagcagtatcatgccaggcaaggtgaaccctactcagtgtgaagcaatgaccatg
gttgcagcccaggtcatggggaatcatgttgctgttacagttggaggcagcaatggacat
tttgagctgaatgttttcaagccaatgatgattaaaaatgtgttgcactcagccagactg
ctaggggatgcttcagtttccttcacagaaaactgtgtcctggggatccaggctaacaca
gaaaggatcaataagctaatgaatgagtctctaatgttggtgacagctctcaatccacat
ataggatatgacaaggcagcaaagattgctaagacagcacacaaaaatggatcaaccttg
aaagaaactgctattgaacttgggtatctcacagcagagcagtttgatgagtgggtgaaa
cctaaagacatgctgggtccgaagtga
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