Oryctolagus cuniculus (rabbit): 100353706
Help
Entry
100353706 CDS
T03373
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01521
EGFR tyrosine kinase inhibitor resistance
ocu01522
Endocrine resistance
ocu01524
Platinum drug resistance
ocu04010
MAPK signaling pathway
ocu04012
ErbB signaling pathway
ocu04014
Ras signaling pathway
ocu04015
Rap1 signaling pathway
ocu04022
cGMP-PKG signaling pathway
ocu04024
cAMP signaling pathway
ocu04062
Chemokine signaling pathway
ocu04066
HIF-1 signaling pathway
ocu04068
FoxO signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04072
Phospholipase D signaling pathway
ocu04140
Autophagy - animal
ocu04150
mTOR signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04152
AMPK signaling pathway
ocu04210
Apoptosis
ocu04211
Longevity regulating pathway
ocu04213
Longevity regulating pathway - multiple species
ocu04218
Cellular senescence
ocu04261
Adrenergic signaling in cardiomyocytes
ocu04370
VEGF signaling pathway
ocu04371
Apelin signaling pathway
ocu04380
Osteoclast differentiation
ocu04510
Focal adhesion
ocu04550
Signaling pathways regulating pluripotency of stem cells
ocu04611
Platelet activation
ocu04613
Neutrophil extracellular trap formation
ocu04620
Toll-like receptor signaling pathway
ocu04625
C-type lectin receptor signaling pathway
ocu04630
JAK-STAT signaling pathway
ocu04660
T cell receptor signaling pathway
ocu04662
B cell receptor signaling pathway
ocu04664
Fc epsilon RI signaling pathway
ocu04666
Fc gamma R-mediated phagocytosis
ocu04668
TNF signaling pathway
ocu04722
Neurotrophin signaling pathway
ocu04725
Cholinergic synapse
ocu04728
Dopaminergic synapse
ocu04810
Regulation of actin cytoskeleton
ocu04910
Insulin signaling pathway
ocu04914
Progesterone-mediated oocyte maturation
ocu04915
Estrogen signaling pathway
ocu04917
Prolactin signaling pathway
ocu04919
Thyroid hormone signaling pathway
ocu04920
Adipocytokine signaling pathway
ocu04922
Glucagon signaling pathway
ocu04923
Regulation of lipolysis in adipocytes
ocu04926
Relaxin signaling pathway
ocu04929
GnRH secretion
ocu04931
Insulin resistance
ocu04932
Non-alcoholic fatty liver disease
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu04935
Growth hormone synthesis, secretion and action
ocu04936
Alcoholic liver disease
ocu04973
Carbohydrate digestion and absorption
ocu05010
Alzheimer disease
ocu05017
Spinocerebellar ataxia
ocu05132
Salmonella infection
ocu05135
Yersinia infection
ocu05142
Chagas disease
ocu05145
Toxoplasmosis
ocu05152
Tuberculosis
ocu05160
Hepatitis C
ocu05161
Hepatitis B
ocu05162
Measles
ocu05163
Human cytomegalovirus infection
ocu05164
Influenza A
ocu05165
Human papillomavirus infection
ocu05166
Human T-cell leukemia virus 1 infection
ocu05167
Kaposi sarcoma-associated herpesvirus infection
ocu05168
Herpes simplex virus 1 infection
ocu05169
Epstein-Barr virus infection
ocu05170
Human immunodeficiency virus 1 infection
ocu05200
Pathways in cancer
ocu05205
Proteoglycans in cancer
ocu05207
Chemical carcinogenesis - receptor activation
ocu05208
Chemical carcinogenesis - reactive oxygen species
ocu05210
Colorectal cancer
ocu05211
Renal cell carcinoma
ocu05212
Pancreatic cancer
ocu05213
Endometrial cancer
ocu05214
Glioma
ocu05215
Prostate cancer
ocu05218
Melanoma
ocu05220
Chronic myeloid leukemia
ocu05221
Acute myeloid leukemia
ocu05222
Small cell lung cancer
ocu05223
Non-small cell lung cancer
ocu05224
Breast cancer
ocu05225
Hepatocellular carcinoma
ocu05226
Gastric cancer
ocu05230
Central carbon metabolism in cancer
ocu05231
Choline metabolism in cancer
ocu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05415
Diabetic cardiomyopathy
ocu05417
Lipid and atherosclerosis
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100353706
04012 ErbB signaling pathway
100353706
04014 Ras signaling pathway
100353706
04015 Rap1 signaling pathway
100353706
04370 VEGF signaling pathway
100353706
04371 Apelin signaling pathway
100353706
04630 JAK-STAT signaling pathway
100353706
04668 TNF signaling pathway
100353706
04066 HIF-1 signaling pathway
100353706
04068 FoxO signaling pathway
100353706
04072 Phospholipase D signaling pathway
100353706
04071 Sphingolipid signaling pathway
100353706
04024 cAMP signaling pathway
100353706
04022 cGMP-PKG signaling pathway
100353706
04151 PI3K-Akt signaling pathway
100353706
04152 AMPK signaling pathway
100353706
04150 mTOR signaling pathway
100353706
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100353706
09143 Cell growth and death
04210 Apoptosis
100353706
04218 Cellular senescence
100353706
09144 Cellular community - eukaryotes
04510 Focal adhesion
100353706
04550 Signaling pathways regulating pluripotency of stem cells
100353706
09142 Cell motility
04810 Regulation of actin cytoskeleton
100353706
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100353706
04613 Neutrophil extracellular trap formation
100353706
04620 Toll-like receptor signaling pathway
100353706
04625 C-type lectin receptor signaling pathway
100353706
04660 T cell receptor signaling pathway
100353706
04662 B cell receptor signaling pathway
100353706
04664 Fc epsilon RI signaling pathway
100353706
04666 Fc gamma R-mediated phagocytosis
100353706
04062 Chemokine signaling pathway
100353706
09152 Endocrine system
04910 Insulin signaling pathway
100353706
04922 Glucagon signaling pathway
100353706
04923 Regulation of lipolysis in adipocytes
100353706
04920 Adipocytokine signaling pathway
100353706
04929 GnRH secretion
100353706
04915 Estrogen signaling pathway
100353706
04914 Progesterone-mediated oocyte maturation
100353706
04917 Prolactin signaling pathway
100353706
04926 Relaxin signaling pathway
100353706
04935 Growth hormone synthesis, secretion and action
100353706
04919 Thyroid hormone signaling pathway
100353706
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100353706
09154 Digestive system
04973 Carbohydrate digestion and absorption
100353706
09156 Nervous system
04725 Cholinergic synapse
100353706
04728 Dopaminergic synapse
100353706
04722 Neurotrophin signaling pathway
100353706
09158 Development and regeneration
04380 Osteoclast differentiation
100353706
09149 Aging
04211 Longevity regulating pathway
100353706
04213 Longevity regulating pathway - multiple species
100353706
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100353706
05205 Proteoglycans in cancer
100353706
05207 Chemical carcinogenesis - receptor activation
100353706
05208 Chemical carcinogenesis - reactive oxygen species
100353706
05230 Central carbon metabolism in cancer
100353706
05231 Choline metabolism in cancer
100353706
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100353706
09162 Cancer: specific types
05210 Colorectal cancer
100353706
05212 Pancreatic cancer
100353706
05225 Hepatocellular carcinoma
100353706
05226 Gastric cancer
100353706
05214 Glioma
100353706
05221 Acute myeloid leukemia
100353706
05220 Chronic myeloid leukemia
100353706
05218 Melanoma
100353706
05211 Renal cell carcinoma
100353706
05215 Prostate cancer
100353706
05213 Endometrial cancer
100353706
05224 Breast cancer
100353706
05222 Small cell lung cancer
100353706
05223 Non-small cell lung cancer
100353706
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100353706
05170 Human immunodeficiency virus 1 infection
100353706
05161 Hepatitis B
100353706
05160 Hepatitis C
100353706
05164 Influenza A
100353706
05162 Measles
100353706
05168 Herpes simplex virus 1 infection
100353706
05163 Human cytomegalovirus infection
100353706
05167 Kaposi sarcoma-associated herpesvirus infection
100353706
05169 Epstein-Barr virus infection
100353706
05165 Human papillomavirus infection
100353706
09171 Infectious disease: bacterial
05132 Salmonella infection
100353706
05135 Yersinia infection
100353706
05152 Tuberculosis
100353706
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100353706
05142 Chagas disease
100353706
09164 Neurodegenerative disease
05010 Alzheimer disease
100353706
05017 Spinocerebellar ataxia
100353706
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100353706
05418 Fluid shear stress and atherosclerosis
100353706
05415 Diabetic cardiomyopathy
100353706
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100353706
04932 Non-alcoholic fatty liver disease
100353706
04931 Insulin resistance
100353706
04933 AGE-RAGE signaling pathway in diabetic complications
100353706
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100353706
01524 Platinum drug resistance
100353706
01522 Endocrine resistance
100353706
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
100353706
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100353706
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100353706
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
ABC1
PH_11
Motif
Other DBs
NCBI-GeneID:
100353706
NCBI-ProteinID:
XP_051676760
Ensembl:
ENSOCUG00000015901
LinkDB
All DBs
Position
16:complement(61445896..61751067)
Genome browser
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGINWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccacgatacttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttaccccctcaacaacttttcagtggcaaagtgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgtcatagagagaacatttcatgtagatactccagaagaaagggaagaatggacagaa
gctatccaggctgtagcagacagactgcaaaggcaagaagaggagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttctacaactcatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagtcattttggttcgagagaaggcaagtgggaaatattatgctatgaagattctgaag
aaagaagtcattattgcaaaggatgaagtggcacacactttaacggaaagcagagtatta
aagaacactagacatccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatggtggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggcaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacattttgtggcacaccagaatatctggcaccagaggtgttagaagac
aatgactatggccgagcagtagactggtggggtctcggggttgtcatgtatgaaatgatg
tgtgggaggttgccgttctacaaccaggaccatgagaaactttttgaactgatactaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagacgatgcaaaagaaattatg
agacatagtttcttttctggaataaactggcaagatgtatatgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagataccagatactttgatgaagaatttaca
gctcagactattacaataacgccacctgagaaatatgatgaggatggtatggactgcatg
gacaatgagaggcggccgcatttccctcagttttcctactctgcaagtggacgggaataa
DBGET
integrated database retrieval system