Oryctolagus cuniculus (rabbit): 100354221
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Entry
100354221 CDS
T03373
Symbol
DIO2
Name
(RefSeq) type II iodothyronine deiodinase
KO
K17904
type II thyroxine 5'-deiodinase [EC:
1.21.99.4
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu04919
Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100354221 (DIO2)
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.21.99 With unknown physiological acceptors
1.21.99.4 thyroxine 5'-deiodinase
100354221 (DIO2)
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Motif
Pfam:
T4_deiodinase
AhpC-TSA
Redoxin
Motif
Other DBs
NCBI-GeneID:
100354221
NCBI-ProteinID:
NP_001243229
UniProt:
A4GNS7
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Position
20:24768945..24780020
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AA seq
269 aa
AA seq
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MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL
RCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSPEAGAGAGNGAQDKTADGAECHLLDFASS
ERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSLAF
EVKKHRNQEDRCAAAHQLLERFSLPPQCRVVADRMDNNANVAYGVAFERVCIVQRQKIAY
LGGKGPFCYNLQEVRRWLEKNFSKRUNLD
NT seq
810 nt
NT seq
+upstream
nt +downstream
nt
atgggcatcctcagcgtagacttgctgatcacactgcagattctgccagtttttttctcc
aactgcctcttcctggcgctctatgactcggtcattctgctcaagcacgtggtgctgctg
ctgagtcgctccaagtccactcgcggagagtggcggcgcatgctgacctcagagggactc
cgctgtgtctggaagagcttcctccttgacgcctacaaacaggtgaaattgggcgaggat
gcccccaattccagtgtggtgcacgtgtccagtcctgaagcaggtgccggtgctgggaat
ggtgctcaggacaagacagcggatggagccgaatgccacctccttgactttgccagctcc
gagcgcccactggtggtcaactttggctcggccacttgacctcctttcaccagccagctg
ccagccttccgcaaactggtggaagagttctcctctgtggctgacttcctgttggtctac
attgatgaggctcatccttcagatggctgggcggtgcctggggactcctctctggctttt
gaggtgaagaagcaccggaaccaggaagaccgatgtgcagcagcccaccagcttctggag
cgtttctccttgccgccccagtgccgggttgtggctgaccgcatggacaataatgccaat
gtagcatacggggtagcctttgaacgcgtgtgcatcgtgcagagacagaaaattgcctat
ctgggaggaaagggtcccttctgctataatcttcaagaagtgcggcgttggctggagaag
aatttcagcaagagatgaaatctagattag
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