KEGG   Oryctolagus cuniculus (rabbit): 100355230
Entry
100355230         CDS       T03373                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04015  Rap1 signaling pathway
ocu04218  Cellular senescence
ocu04380  Osteoclast differentiation
ocu04620  Toll-like receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04912  GnRH signaling pathway
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05014  Amyotrophic lateral sclerosis
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05135  Yersinia infection
ocu05145  Toxoplasmosis
ocu05161  Hepatitis B
ocu05163  Human cytomegalovirus infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100355230
   04015 Rap1 signaling pathway
    100355230
   04668 TNF signaling pathway
    100355230
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100355230
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100355230
   04664 Fc epsilon RI signaling pathway
    100355230
  09152 Endocrine system
   04912 GnRH signaling pathway
    100355230
   04935 Growth hormone synthesis, secretion and action
    100355230
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100355230
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100355230
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100355230
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100355230
   05161 Hepatitis B
    100355230
   05163 Human cytomegalovirus infection
    100355230
   05167 Kaposi sarcoma-associated herpesvirus infection
    100355230
   05169 Epstein-Barr virus infection
    100355230
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100355230
   05135 Yersinia infection
    100355230
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100355230
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100355230
   05022 Pathways of neurodegeneration - multiple diseases
    100355230
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100355230
   05418 Fluid shear stress and atherosclerosis
    100355230
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100355230
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100355230
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100355230
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: STE group
  STE7 family
   100355230
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 100355230
NCBI-ProteinID: XP_008269979
Ensembl: ENSOCUG00000007606
UniProt: G1STE8
LinkDB
Position
19:50691956..50830547
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTVHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaaaaaacgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggttaaggcagatgacctggaacctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctattgatggatttg
gatatttccatgaggacagtggactgtccctttactgtcaccttttatggcgccctcttc
cgggagggtgatgtctggatctgcatggagctcatggatacatcactagataaattctac
aaacaagtcattgataaaggccaaacaattccagaggacatcttagggaaaatagctgtt
tctattgtaaaagcattagaacatttacacagtaagctctctgtcattcatcgagacgtc
aagccttctaatgtgctgattaataccctgggccaagtgaagatgtgtgactttggaatc
agtggctacctggtggattcagttgctaaaacaattgatgcaggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagttggccatcctccggtttccctatgattcttgg
ggcactcccttccagcaactcaaacaggtggtagaagagccatcgccacaactcccagca
gacaagttctctgcagaatttgttgactttacctcacagtgcttgaagaagaattccaaa
gaaaggcctacatatccagagcttatgcaacatccattcttcactgtacatgaatccaaa
gcaacagatgtggcatcttttgtaaaattgattcttggagactaa

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