KEGG   Oryctolagus cuniculus (rabbit): 100355970
Entry
100355970         CDS       T03373                                 
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00061  Fatty acid biosynthesis
ocu00620  Pyruvate metabolism
ocu00640  Propanoate metabolism
ocu01100  Metabolic pathways
ocu01212  Fatty acid metabolism
ocu04152  AMPK signaling pathway
ocu04910  Insulin signaling pathway
ocu04922  Glucagon signaling pathway
ocu04936  Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    100355970
   00640 Propanoate metabolism
    100355970
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    100355970
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    100355970
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    100355970
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100355970
   04922 Glucagon signaling pathway
    100355970
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100355970
Enzymes [BR:ocu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     100355970
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     100355970
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     100355970
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 100355970
NCBI-ProteinID: XP_002719123
Ensembl: ENSOCUG00000014453
LinkDB
Position
19:23098620..23415379
AA seq 2346 aa
MEETSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGVSSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVNWQENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVPPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKGWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVQSSVPLLSSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPAE
RKELESKLKEREEFLTPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISATQRAEVVRILST
MDSPST
NT seq 7041 nt   +upstreamnt  +downstreamnt
atggaggaaacatctcccttggccaagcctctggagctgaaccagcactcccgctttata
attggttctgtgtccgaagataactcggaggatgagatcagcaacctggtgaagctggac
ttgctggaagagaaggagggctctctgtctccagcttctgtcagctcagatactctgtct
gatttgggggtctctagcctgcaggatggcttggccttgcatatcaggtccagcatgtct
ggcttgcatctagtgaagcaaggtcgagaccgaaagaaaatcgactcacagcgggatttc
actgtggcttctccggcagaatttgttactcgttttgggggaaataaagtcattgagaag
gttcttattgctaacaacggcattgcagcagtgaaatgcatgcggtccatccgccggtgg
tcttatgaaatgtttaggaatgagcgtgcgatccgatttgttgtcatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactacgtgccagtgcctgga
ggcccgaacaacaacaactatgctaatgtggaattaattcttgatatcgcgaaaaggatc
ccagtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttctcttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcaaactgcaggaatcccaactcttccctgg
agtggcagtggtcttcgtgtgaactggcaagaaaatgatttttcaaaacgtatcttaaat
gttccccaggaactgtatgaaaaaggttatgtgaaggatgtggatgatgggctaaaggca
gcagaagaagttggatatccagtgatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaagtcaacaatgcagatgacttccctaaccttttcagacaggttcaagctgaa
gtccctgggtctcctatatttgtgatgaggcttgccaaacagtctcgtcatctggaagtg
cagatcctagcagaccagtatggaaatgccatctctctgtttggtcgtgactgctccgta
cagcgcaggcatcagaagattattgaagaggcgcctgctgctattgctactccagcagtg
tttgaacatatggaacagtgtgcagtgaaactggccaaaatggttggttatgtgagtgct
ggaacggtggagtacctttacagccaggatgggagcttctactttctggagctgaaccct
cgactgcaggtggaacacccttgtacagagatggtggctgatgtcaatctcccagcagcg
cagctccagattgccatggggattcctctatataggatcaaggatatccggatgatgtat
ggggtacctccctggggcgatgctcctattgattttgaaaattctgctcacgttccttgc
ccaaggggccatgtgattgctgcccggatcaccagtgaaaatcctgatgaggggtttaag
cccagctcgggaacagttcaggagctgaatttccgcagcaacaagaatgtttggggttat
ttcagtgttgctgctgcagggggactccatgaatttgctgattctcagtttggtcactgc
ttctcctggggagaaaaccgagaagaagcgatttcaaacatggtggtggctttgaaggag
ctgtctatccgcggtgacttccgaactacagttgagtacctgatcaaattgttagaaacg
gaaagctttcagctgaacaggatcgacactggctggctggacaggctaatagcagaaaaa
gtacaggcagaacgccctgacaccatgttgggagttgtgtgtggggctctccatgtggca
gatgtgagcctgcggaatagcatctccaatttccttcactccttggaaaggggtcaagtc
cttcctgctcatacacttctgaacacagtagatgttgaacttatttatgagggagtcaag
tatgtacttaaggtgacgcgccagtctcccaactcctacgtggtcatcatgaatggctcc
tgtgtggaggtggatgtacacaggctcagtgatgggggtctgctcctgtcctacgacggc
agcagttacacaacatacatgaaggaggaagtggatagataccgcatcacgattggcaat
aaaacctgtgtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttcggctggg
aagttaatccagtacattgtggaggacggaggccacgtgtttgctgggcagtgctatgct
gagattgaggtgatgaagatggtgatgaccttaacggctgcagaatctggctgtatccat
tatgtcaagcgaccaggagcagctcttgatcctggttgtgtcatagccaaaatgcagttg
gataaccccagcaaggttcagcaggcggagcttcacacaggcagcctgccgcagatccag
agcacagcgctgcgcggcgagaagctccatcgagtgttccactacgtgctggataacctg
gttaacgtgatgaatggctactgccttcctgaccctttcttcagcagcaaggtaaagggc
tgggtagaacggttgatgaagaccctcagagatccttccttgcctctcctagaattacaa
gatatcatgaccagtgtctccggccgcatacccctcaatgtggagaagtccattaagaag
gaaatggctcagtatgctagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctggatagccatgcagccacactgaaccggaagtctgaacgggaggtc
ttcttcatgaacacacagagcattgtccagctggtgcagaggtaccgaagtggcatccga
ggccacatgaaggcagtggtgatggatctgctccggcagtacctgcgagtggagacacaa
ttccagaatggtcactatgacaaatgtgtgtttgcccttcgggaggagaacaaaagtgac
atgaacactgtcttgaactacatcttctctcatgctcaagtcaccaagaagaatcttctg
gttactatgcttattgatcagctgtgtggccgggatcctactctcactgatgagctgctg
aatatcctcacggagctaactcagctcagtaagactaccaatgctaaggtggcactccgc
gctcgccaggttcttattgcctcccatttgccatcgtacgagcttcgccataaccaagtg
gagtctatcttcttatcggctattgacatgtatggacaccagttctgcattgagaatctg
cagaaactcatcctatctgaaacatctatttttgatgtcctgccaaacttcttctatcac
agcaaccaggtggtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcc
tacgaactgaacagtgtacagcaccgccagcttaaggacaacacgtgtgtggtggagttc
cagttcatgctgcctacatctcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcatgtagctagtgtgagtgatgtg
ctattggacaactcattcactccaccgtgtcagcggatgggcggaatggtctcttttcgg
acttttgaagattttgtcaggatcttcgatgaagtgatgggttgcttctgtgactcccca
cctcaaagccccacattcccagaggcaggccacacatctctgtatgatgaagacaaggtc
cccagggatgaaccaatccacattctgaatgtggctatcaagactgactgtgatattgaa
gatgacaggctggcagccatgttcagagagttcacccagcagaataaagctaccctggtt
gaacatgggatccggcgccttactttcctggttgcacaaaaggacttcagaaaacaagtc
aactatgaggtggatcagagatttcatagagaatttcctaaatttttcacattccgagca
agggataagtttgaggaagatcgtatttatcgtcacttggaacctgctctggcattccag
ttagagctaaaccgcatgagaaattttgacctaactgccattccatgtgccaatcacaag
atgcacctgtaccttggggcagccaaggtggaagtaggcacagaagtgacagactacaga
ttcttcgttcgtgcaatcatcagacactctgatctggtcaccaaggaagcttcttttgaa
tatttacaaaatgaaggagagcgactacttctggaagccatggatgagctggaagttgct
tttaacaatacaaatgtccgcaccgactgtaatcacatcttcctcaactttgtgcccaca
gttatcatggacccatcaaagattgaggaatctgtgagaagcatggtaatgcgctatgga
agtcggctgtggaaattgcgtgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccaactggaaaagcaattcccattcgcctcttcctgacaaacgagtctggctattacttg
gacatcagcctctacaaggaagtgactgactccaggactgcacagatcatgtttcaggca
tatggagacaaacagggaccactgcatggaatgttaatcaatactccctatgtgaccaaa
gatcttcttcaatcaaagagattccaggcacaatccctggggacaacatacatatatgat
atcccagagatgtttcggcagtccttgatcaaactctgggagtctatgtccacgcaagca
ttccttccttcaccccctctgccttcggacatgttgacgtataccgagctggtgttggat
gatcaaggtcaactggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgacccttaaaagtcctgaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacataccgaattgggtcctttgggccccaggaagatttgctgtttctc
agagcttctgaacttgccagggcagagggcattccacgcatctttgtagcagccaacagt
ggtgcaagaattggactggcagaagaaattcgtcatatgttccatgtggcctgggtagat
cctgaggatccttacaagggatacaagtatttatatctgacccctcaagattataagagg
gtcagtgctctcaactctgtccactgtgaacatgtggaagatgaaggagaatctaggtac
aagataacggatattattgggaaggaagagggacttggagcagagaaccttcgaggttct
ggaatgattgctggggagtcttccttggcctatgacgagatcatcaccattagcctggtg
acgtgccgggccattgggattggggcttaccttgtccgactgggacagagaacgatccag
gttgagaattctcatttaattctcacaggcgctggggccctcaacaaagtcctcgggcgg
gaagtgtacacctccaataaccagctcgggggcatccagatcatgcacaacaacggggtg
acccacagcaccgtgtgtgatgactttgaaggggtgttcactgtcctgcactggctgtcc
tacatgcccaagagtgtgcaaagttcagttcccctcctgagctccaaggatcctatagat
agaatcatcgagtttgtccccacaaaggctccatatgaccctcgatggatgctggcaggc
cgccctcacccaacccagaaaggtcagtggttgagtggattttttgactacggatcgttc
tcggagattatgcagccctgggcacagaccgtggtggttggtagagccaggctaggggga
atacctgtgggagtagttgctgtagaaactcgaacagtagaactaagtatcccagctgat
cctgcaaacctggattctgaagccaagataatacagcaagctggccaagtttggtttcca
gactctgcatttaagacctatcaggccatcaaggacttcaaccgcgaagggctgcctctg
atggtctttgccaactggagaggcttctctggtgggatgaaagatatgtacgatcaagtg
ctgaagtttggtgcttacatcgtggacagcttgcgagagtgctcccagcctgtgatggtt
tacattcctccccaggccgagctgcggggtggctcctgggtggtgatcgaccccaccatc
aaccctcggcacatggagatgtatgccgacagagaaagcaggggatcagtcctggagcca
gaagggacagtagaaatcaaattccgcaaaaaggatctagtgaaaaccatgcgtcgggtg
gacccagtctacatccgcttggctgagcgattgggcaccccagagctgagccccgccgag
cggaaggagctggagagcaagttgaaggagcgggaggagttcctgactcccatctaccat
caggtcgccgtgcagtttgccgacctgcacgacaccccgggccggatgcaggagaagggt
gtgattaacgacatcctggactggaagacatcccgcaccttcttctactggcggctgaga
cgtctcctgctggaggacctggtcaagaagaaaatccacaacgccaaccctgagctcacg
gacggccagatccaggccatgttaaggcgctggtttgtggaagtagaaggaacagtgaag
gcctatgtttgggacaacaacaaggacctggtggagtggctggagaagcagctgaccgag
gaggacggcgtccgctcggtgatcgaggagaacatcaagtacatcagccgagactacgtc
ctcaagcagatccgcagcttggtacaggccaacccggaggtcgccatggattccatcgtc
cacatgacccagcacatctcagccacgcagcgggccgaagtcgtccggatcctctccacg
atggactccccttccacgtag

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