KEGG   Oryctolagus cuniculus (rabbit): 103346035
Entry
103346035         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04010  MAPK signaling pathway
ocu04015  Rap1 signaling pathway
ocu04068  FoxO signaling pathway
ocu04071  Sphingolipid signaling pathway
ocu04114  Oocyte meiosis
ocu04148  Efferocytosis
ocu04218  Cellular senescence
ocu04261  Adrenergic signaling in cardiomyocytes
ocu04370  VEGF signaling pathway
ocu04380  Osteoclast differentiation
ocu04550  Signaling pathways regulating pluripotency of stem cells
ocu04611  Platelet activation
ocu04613  Neutrophil extracellular trap formation
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04625  C-type lectin receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04658  Th1 and Th2 cell differentiation
ocu04659  Th17 cell differentiation
ocu04660  T cell receptor signaling pathway
ocu04664  Fc epsilon RI signaling pathway
ocu04668  TNF signaling pathway
ocu04670  Leukocyte transendothelial migration
ocu04714  Thermogenesis
ocu04722  Neurotrophin signaling pathway
ocu04723  Retrograde endocannabinoid signaling
ocu04728  Dopaminergic synapse
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04912  GnRH signaling pathway
ocu04914  Progesterone-mediated oocyte maturation
ocu04917  Prolactin signaling pathway
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04936  Alcoholic liver disease
ocu05014  Amyotrophic lateral sclerosis
ocu05020  Prion disease
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05132  Salmonella infection
ocu05133  Pertussis
ocu05135  Yersinia infection
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05145  Toxoplasmosis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05163  Human cytomegalovirus infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05205  Proteoglycans in cancer
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103346035
   04015 Rap1 signaling pathway
    103346035
   04370 VEGF signaling pathway
    103346035
   04668 TNF signaling pathway
    103346035
   04068 FoxO signaling pathway
    103346035
   04071 Sphingolipid signaling pathway
    103346035
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103346035
  09143 Cell growth and death
   04114 Oocyte meiosis
    103346035
   04218 Cellular senescence
    103346035
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103346035
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103346035
   04613 Neutrophil extracellular trap formation
    103346035
   04620 Toll-like receptor signaling pathway
    103346035
   04621 NOD-like receptor signaling pathway
    103346035
   04622 RIG-I-like receptor signaling pathway
    103346035
   04625 C-type lectin receptor signaling pathway
    103346035
   04660 T cell receptor signaling pathway
    103346035
   04658 Th1 and Th2 cell differentiation
    103346035
   04659 Th17 cell differentiation
    103346035
   04657 IL-17 signaling pathway
    103346035
   04664 Fc epsilon RI signaling pathway
    103346035
   04670 Leukocyte transendothelial migration
    103346035
  09152 Endocrine system
   04912 GnRH signaling pathway
    103346035
   04914 Progesterone-mediated oocyte maturation
    103346035
   04917 Prolactin signaling pathway
    103346035
   04926 Relaxin signaling pathway
    103346035
   04935 Growth hormone synthesis, secretion and action
    103346035
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103346035
  09156 Nervous system
   04728 Dopaminergic synapse
    103346035
   04723 Retrograde endocannabinoid signaling
    103346035
   04722 Neurotrophin signaling pathway
    103346035
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103346035
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103346035
  09159 Environmental adaptation
   04714 Thermogenesis
    103346035
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103346035
   05208 Chemical carcinogenesis - reactive oxygen species
    103346035
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103346035
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103346035
   05161 Hepatitis B
    103346035
   05171 Coronavirus disease - COVID-19
    103346035
   05163 Human cytomegalovirus infection
    103346035
   05167 Kaposi sarcoma-associated herpesvirus infection
    103346035
   05169 Epstein-Barr virus infection
    103346035
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103346035
   05135 Yersinia infection
    103346035
   05133 Pertussis
    103346035
   05152 Tuberculosis
    103346035
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103346035
   05140 Leishmaniasis
    103346035
   05142 Chagas disease
    103346035
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103346035
   05020 Prion disease
    103346035
   05022 Pathways of neurodegeneration - multiple diseases
    103346035
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103346035
   05418 Fluid shear stress and atherosclerosis
    103346035
   05415 Diabetic cardiomyopathy
    103346035
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103346035
   04932 Non-alcoholic fatty liver disease
    103346035
   04933 AGE-RAGE signaling pathway in diabetic complications
    103346035
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103346035
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    103346035
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103346035
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103346035
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 103346035
NCBI-ProteinID: XP_051695176
LinkDB
Position
Unknown
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPVAEPYDESVEAKERTVEEWKELTYQEVLSFKPPESPQPSGSL
DIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcggggccccgcgccggcttctaccggcaggagctgaacaagacggtgtgggaggtg
ccgcagaggctgcaggggctgcgcccggtgggctccggcgcctacggctcggtctgctca
gcctacgacgcccggctgcggcagaaggtggcggtgaagaagctctcgcggcccttccag
tcgctgatccacgcccgcaggacgtaccgggagctgcggctgctcaagcacctcaagcat
gagaacgtcatcgggcttctggacgtcttcacgccagccacgtccatcgaggacttcagt
gaagtgtacttggtgaccaccctgatgggcgcagacctgaacaacatcgtcaagtgccag
gcgctgagtgacgaacacgtccagttcctggtataccagctgctgcgtgggctgaagtac
atccactctgcagggatcatccaccgggacctgaaacccagcaacgtggcggtgaatgaa
gactgcgagctcaggatcctagacttcggactggcccgccaggctgacgaggagatgacc
ggctacgtggccacacgctggtaccgagccccagagatcatgctgaactggatgcactac
aaccagacagtggatatctggtccgtgggctgtatcatggccgagctgctgcaggggaag
gctctcttcccgggaagtgactacatcgaccagctgaagcggatcatggaggtggtgggt
acgcccagccctgaggttctggccaagatttcctcggagcacgcccggacctacatccag
tctctgccccccatgcctcagaaggacctcagcagcatcttccgcggagccaaccccctg
gctatagatctcctcgggaggatgctggtgctggacagcgaccagcgggtcagcgccgcg
gaggccctggcccacgcctacttcagccagtaccacgaccccgacgatgagccggtggcc
gagccctatgatgaaagcgttgaggccaaggagcgcacagtggaggagtggaaggagctc
acctaccaggaggttctcagcttcaagcccccggagtcaccacagccatctggtagcctg
gacattgagcagtga

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