Ochotona curzoniae (black-lipped pika): 121146092
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Entry
121146092 CDS
T11174
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00230
Purine metabolism
ocz01100
Metabolic pathways
ocz04024
cAMP signaling pathway
ocz05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121146092 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
121146092 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
121146092 (PDE10A)
Enzymes [BR:
ocz01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
121146092 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
121146092 (PDE10A)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
121146092
NCBI-ProteinID:
XP_040821311
LinkDB
All DBs
Position
Unknown
AA seq
1050 aa
AA seq
DB search
MASPPEPRAPRPQAPLPAAGDEPGPGPGKLRPEARRGAAPERPGRGRAERAAPPRAPPSP
AGRVGSAGGPGALSALGGCWVAARAPFALALSSPAPSASPSSFYFWPPPPLPPPSFLPSS
AAFHLPARLPGREGAAAGGGGGGGDAGGGGGQEAAPLSVPASSSPRGGGGGGRRRLFLSL
ALQGLLLPARAGPRAPPPRLPFGAAARRVGFPGFPGAGGGCPGPAGGGGGRHRDRTPQRP
GGAGCALASLLLGSDMEDGPSGNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVS
ESVSAETVEKWLKRKNNKPEDESTHKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLL
LYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGLKEGRPRLIPAGPITQGTTISAYV
AKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAF
CLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIM
IYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVA
RTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSK
TDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFTLP
ARLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYH
NWKHAVTVAHCMYAILQNTYGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAAL
YSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQL
EEMCQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKK
LGLQPIPMMDRDKWDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKV
IRGEETALWISAPPAAPDAGEKLPPGKTDN
NT seq
3153 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccgccggagcctcgcgctccccgcccccaggctcccctgcccgcggcgggg
gacgagccgggcccgggccccggcaaactccgcccggaagcccggcgcggcgcggccccg
gagcggccaggccgcgggcgggccgagcgcgccgcgcccccgcgcgcgcccccctccccg
gcaggccgcgtgggctcggccggggggcccggcgcgctctcggcgctcggcggctgctgg
gtcgcggcccgggcccccttcgcgctcgcgctctcctcccccgccccctcggcctcccca
tcttccttttacttctggccgccgccgcccctgccccctccctcgtttctcccctcctca
gccgcctttcacctccccgcgcgtctcccaggaagggagggcgcggcggcgggaggaggt
ggaggcggcggcgatgctggcggcggcggaggacaagaggcagctccgctgagcgtcccc
gccagcagcagtccgcgcggcggcggcggcggcgggcggcggcgcctcttcctctcgctc
gcgctccaaggcttgctgctccccgcgcgcgccgggccccgagcgccgccgccccggctg
cccttcggcgcggccgcccggcgcgtgggcttccccggcttcccgggcgccggcgggggc
tgccccggccccgccggcggaggcggcggccgccaccgtgaccgaactccacagcggccc
ggaggcgccggctgtgcgctcgcctcgcttcttctcggctccgacatggaagatggacct
tctggtaacgcgagctgcttccgaaggctgaccgagtgtttcctgagccccagtttgaca
gatgaaaaagtgaaggcctatctttctcttcacccccaggtattagatgaatttgtttct
gaaagcgttagtgcagagaccgtagaaaaatggctgaagaggaagaacaacaagcccgaa
gatgaatcgactcataaggaagtcagcaggtaccaagacacaaatatgcaaggagttgta
tatgaactaaacagctacatagagcaacggctggatactgggggagacaaccaactgctt
ctctacgagctgagcagcatcattaaaatagctacaaaagccgatggatttgcactgtat
ttccttggagagtgcaataacagcctgtgtgtgttcacaccccctgggttgaaggaaggc
aggccccggctcatccccgctgggcccatcacccagggcaccaccatctctgcgtatgtg
gccaagtcaaggaaaacgctgctggtggaagacatccttggggatgagcgatttccaaga
ggtacgggactggaatcagggactcgtatccagtctgttctttgcttgcccattgtcact
gccatcggagatttgattggcattctcgagctgtatcgtcactggggcaaagaagccttc
tgcctgagtcaccaggaggttgcgacagcaaatcttgcctgggcctcggtagcaatccat
caggtgcaggtgtgccgaggtcttgccaaacagactgaactgaatgactttctcctcgac
gtgtcaaaaacgtattttgataatatagtcgcaatagattctctacttgaacacataatg
atatatgcaaagaacctggtgaatgccgaccgctgtgccctcttccaggtagaccataaa
aacaaggagctatattcagacctttttgatattggagaggagaaggagggcaagcctgtc
ttcaagaagaccaaagagataagattttcaattgagaagggcattgctggtcaggtagcc
agaacaggagaggtcctgaacatcccagacgcctacgctgacccgcgcttcaacagagaa
gtggacttgtacacgggctacaccacacggaacatcctgtgcatgcccatcgtgagccga
ggcagcgtgatcggcgtggtgcagatggtgaacaagatcagcggcagcgccttctccaag
acggacgagaacaacttcaagatgtttgctgtcttttgtgctttggccttgcactgtgct
aatatgtaccacaggatccgtcactcggagtgcatctaccgggtgaccatggagaagctg
tcttaccacagcatctgcacggcggaggagtggcaaggcctcatgcgctttaccctgccc
gctcgcctctgcaaggagattgaactgttccactttgacatcggtccttttgaaaacatg
tggcctgggatatttgtctacatggtccatcggtcctgtgggacttcctgctttgagctc
gagaagttgtgccgcttcatcatgtctgtgaagaagaactaccggcgggttccctaccac
aactggaagcacgcggtgacggtggctcactgcatgtacgccatactgcagaacacctac
gggctcttcactgacctggagcgcaaaggcctgctgatcgcgtgtctgtgtcacgacctg
gaccacaggggcttcagtaacagctatctgcagaagttcgaccacccactggccgctctc
tactccacctccaccatggagcagcaccacttctcacagacggtgtccatcctgcagttg
gagggacacaacatcttctccacgctgagctccagtgagtacgaacaggtgcttgagata
atccgcaaagccatcattgccacagacctcgccctgtacttcggcaacaggaagcagttg
gaagagatgtgccagactggatcgctaaaccttaacaaccagtctcatagagaccgggtg
atcggtttgatgatgacggcctgtgacctctgttccgtgacgaaactgtggccggttaca
aaactgacagccaatgacatttatgcggagttctgggccgagggtgatgaaatgaagaaa
ttgggcctacagcctattcccatgatggacagagacaagtgggatgaggtcccgcaaggc
cagctgggattctacaacgctgtagccatcccctgttacaccaccctcacccagatccta
cctcccaccgagcctctgctcaaagcctgcagggacaacctcaatcagtgggagaaagtg
atccgaggggaggagacggccttgtggatctcggccccaccggcagcccctgacgccgga
gagaagctgccacctgggaaaacggacaactga
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