Ochotona curzoniae (black-lipped pika): 121148868
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Entry
121148868 CDS
T11174
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz01521
EGFR tyrosine kinase inhibitor resistance
ocz01522
Endocrine resistance
ocz04010
MAPK signaling pathway
ocz04014
Ras signaling pathway
ocz04015
Rap1 signaling pathway
ocz04066
HIF-1 signaling pathway
ocz04068
FoxO signaling pathway
ocz04081
Hormone signaling
ocz04114
Oocyte meiosis
ocz04140
Autophagy - animal
ocz04144
Endocytosis
ocz04150
mTOR signaling pathway
ocz04151
PI3K-Akt signaling pathway
ocz04152
AMPK signaling pathway
ocz04211
Longevity regulating pathway
ocz04213
Longevity regulating pathway - multiple species
ocz04510
Focal adhesion
ocz04520
Adherens junction
ocz04550
Signaling pathways regulating pluripotency of stem cells
ocz04730
Long-term depression
ocz04913
Ovarian steroidogenesis
ocz04914
Progesterone-mediated oocyte maturation
ocz05200
Pathways in cancer
ocz05202
Transcriptional misregulation in cancer
ocz05205
Proteoglycans in cancer
ocz05214
Glioma
ocz05215
Prostate cancer
ocz05218
Melanoma
ocz05224
Breast cancer
ocz05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121148868 (IGF1R)
04014 Ras signaling pathway
121148868 (IGF1R)
04015 Rap1 signaling pathway
121148868 (IGF1R)
04066 HIF-1 signaling pathway
121148868 (IGF1R)
04068 FoxO signaling pathway
121148868 (IGF1R)
04151 PI3K-Akt signaling pathway
121148868 (IGF1R)
04152 AMPK signaling pathway
121148868 (IGF1R)
04150 mTOR signaling pathway
121148868 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
121148868 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
121148868 (IGF1R)
04140 Autophagy - animal
121148868 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
121148868 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121148868 (IGF1R)
04520 Adherens junction
121148868 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
121148868 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
121148868 (IGF1R)
04914 Progesterone-mediated oocyte maturation
121148868 (IGF1R)
09156 Nervous system
04730 Long-term depression
121148868 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
121148868 (IGF1R)
04213 Longevity regulating pathway - multiple species
121148868 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121148868 (IGF1R)
05202 Transcriptional misregulation in cancer
121148868 (IGF1R)
05205 Proteoglycans in cancer
121148868 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
121148868 (IGF1R)
05214 Glioma
121148868 (IGF1R)
05218 Melanoma
121148868 (IGF1R)
05215 Prostate cancer
121148868 (IGF1R)
05224 Breast cancer
121148868 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121148868 (IGF1R)
01522 Endocrine resistance
121148868 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocz01001
]
121148868 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ocz04090
]
121148868 (IGF1R)
Enzymes [BR:
ocz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
121148868 (IGF1R)
Protein kinases [BR:
ocz01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
121148868 (IGF1R)
CD molecules [BR:
ocz04090
]
Proteins
121148868 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Other DBs
NCBI-GeneID:
121148868
NCBI-ProteinID:
XP_040825146
LinkDB
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Position
Unknown
AA seq
1392 aa
AA seq
DB search
MKAGFGGGSWTSLWGLLLVAVALLLWPTSGEICGPGIDIRNDFQQLKRLENCTVIEGFLH
ILLISKAEDYRNYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLHNLRNITRGAIRIEKNADLCFLSTVDWSLILDAVPNNYIVGNKPPKECGD
LCPGVLEGKPTCEKTAINNEYNYRCWTANRCQKMCPSSCGKRACSDNNECCHPECLGSCY
APDDNTACVACLHYYHDGTCVTSCPPNTYRFEGWRCVDRDFCANILSVDEGEGFVIHDGE
CMQECPSGFIRNGSQSMFCVPCEGPCPKVCEEDKKTKTIDSVNSAQMLQGCTIFKGNLLI
NIRRGNNIASELESFMGLIEVVTGYVKISHSHALVSLSFLKNLRLILGEEQLEGNYSFYV
LDNQNLQQLWDWEHRNLTIKTGKMYFAFNPKLCVSEIYRMEDVTGTKGRQSKGDINTRNN
GERASCESDILHFTNTATGKNRIILTWHRYRPPDYRDLISFTVYYKEAPHKNVTEYDGQD
ACGSNSWNMVDVDLPPDKDTEPGILLQGLKPWTQYAIYVKAVTLTMVENDHIRGAKSDIL
YVRTNASVPSVPLDILSASNSSSQLIVKWSAPSLPNGNLSYYIVRWQQQPQDAYLYRHNY
CSKEDKIPVRKYADGMIDFEEVTENPKMEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKV
FENFLHNSIFVPRPERKRRDVVHMTDMASSGRGRNTTAENSYNTTDPDEPETDFPFFESR
VDREITVISNLRPFTSYRIDIHSCNHEAEKLGCSASNFVFARTKPAEGADDIPGPVTWEA
QPENSVFLKWPEPENPNGLILMYEIKYGSLMEDQRECISRQHYRKYGGIKLNRLNPGNYT
ARIQATSLSGNGSWTDPVFFYVPDKAADEGYSHLTVVLPVAIVFVVGGLLVFLYILHRKR
TRMGNGVLYASVNPEYFSAADVYIPDEWEVARDKITMNRELGQGSFGMVYEGVAKGVVKD
EPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTR
GDLKSYLRSLRPEIENNPAFAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA
EDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWE
IATLAEQPYQGFSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLDILG
SVKDELEPGFREVSFYYSDDNKAPEAEAEAEALALAQAQAQAEAEVEDEDDELELEPEDM
ESVPLDPSAAAAAAVAALGIPLPDRHKPENGPGLGAMVLCASCEEQRRRPYSHMNGGRTD
ERALPLPQSSTC
NT seq
4179 nt
NT seq
+upstream
nt +downstream
nt
atgaaggctggcttcggaggagggtcttggacctcgctctgggggctcctgcttgtcgcc
gtcgcactcctgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aatgacttccagcagctgaagcgcctggagaactgcacggtgatcgagggcttcctgcac
atcctgctcatctccaaggccgaggactaccgcaactaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctcttccgggtggccggcctcgagagcctgggggacctcttc
ccgaacctcacggtcatccgcggctggaagctcttctacaactatgccctggtcatcttc
gagatgactaaccttaaggacatagggctgcataacctgaggaacatcacccggggcgcc
atcaggatcgagaagaacgccgacctctgcttcctctccacggtggactggtcgctcatc
ctggacgccgtgcccaacaactacattgtggggaacaagcccccgaaggagtgtggggac
ctgtgccccggggtcctggaggggaagccaacatgtgagaagaccgccatcaataacgag
tacaactaccgctgctggactgccaaccgctgccagaaaatgtgcccaagctcgtgcggg
aagcgagcctgctcggacaacaacgaatgctgccaccctgagtgcctgggcagctgctat
gcacccgatgacaacactgcctgcgtcgcctgcctccactactatcatgatggcacctgt
gtgacaagctgcccgcccaacacctaccgatttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatcctcagcgtcgacgaaggcgagggcttcgtcatccatgacggcgag
tgcatgcaggagtgcccctcggggttcatccgcaacggcagccagagcatgttctgcgtc
ccttgcgaaggtccttgccccaaggtctgtgaggaagacaagaaaacaaagaccattgat
tctgtaaattctgctcaaatgctccaaggctgcaccatcttcaagggcaatttgctcatt
aatatccgacgaggcaataacattgcctcagagctggagagcttcatggggctcatcgag
gtggttacgggctatgtgaagataagccactcgcacgccttggtctccttgtccttcctg
aagaatctccgcctgattctcggagaggagcagctggaaggaaactactccttctatgtc
ctggacaaccagaacctacagcagctctgggactgggaacaccgcaacctgaccatcaaa
actgggaagatgtacttcgccttcaatcccaaactctgcgtgtctgaaatttaccgcatg
gaggacgtgacaggaactaaagggcgccagagcaaaggcgacattaacacccggaacaat
ggagagagagcctcctgtgagagtgacatcctgcacttcaccaacactgccactggtaag
aaccgcatcattctcacctggcaccgctaccggcccccggactacagggatctcatcagc
ttcaccgtctactacaaggaggcaccccataaaaacgtgacggaatatgatgggcaggac
gcctgtggctccaacagctggaacatggtggacgtggacctcccccctgacaaggacaca
gagcccggcatcctactgcaggggctgaagccctggactcagtatgccatctatgtcaaa
gccgtgaccctcaccatggtggaaaacgaccacatccgtggggccaagagtgacatctta
tacgttcgcaccaatgcttcagttccttccgtccccctggatattctttcggcatcgaac
tcctcttctcagctgatcgtgaagtggagcgccccctccctgcccaatggcaacctgagc
tactacatcgtgagatggcagcagcagcctcaggacgcctacctgtaccgacacaattac
tgctccaaagaagataaaattcccgtgaggaagtacgcagatggcatgatcgactttgaa
gaagtaaccgagaatcccaagatggaggtgtgcggtggggagaaggggccgtgctgtgcc
tgccccaaaaccgaagccgagaagcaggctgagaaagaggaggcggagtaccgcaaagtg
tttgagaacttcctgcacaactccatcttcgtgcccaggcccgagagaaagcgaagggac
gtcgtgcacatgacagatatggcctcgtccggccgaggcaggaacaccacggcggagaac
tcctacaacaccacggaccccgacgagccggagacggatttccctttctttgagagcaga
gtggacagggagataacagtgatatccaacctccgcccgttcacttcctaccgcatcgac
attcacagttgtaaccacgaggccgagaaactggggtgcagcgcctccaactttgtcttt
gcaagaaccaaacctgcagaaggagcagatgacattcccggcccagtgacctgggaagca
cagcctgaaaactccgtctttctaaagtggccagaacctgagaatcccaacggattgatc
ctgatgtatgagatcaaatacggttctctaatggaggaccagcgggagtgtatatccaga
cagcactaccggaagtacgggggaatcaaactgaaccggctaaaccccggcaactacaca
gcccggattcaggccacgtctctctctgggaacgggtcatggactgatcctgtgttcttc
tatgtcccagacaaagctgccgacgaaggctactcgcacctgacggtcgtgctgcccgtg
gccatcgtgttcgtcgtgggagggctgctggtcttcctgtacatcctgcacaggaagcgt
accagaatgggcaacggcgtgctctatgcctctgtgaacccggagtacttcagcgcagct
gatgtgtatatccctgatgagtgggaggtcgcacgcgataagatcaccatgaaccgagag
ctggggcagggctccttcgggatggtctacgaaggtgtcgccaaaggcgtggtcaaggat
gagcccgagaccagggtggccatcaagactgtgaacgaggctgccagcatgcgggaaagg
attgaatttctcaatgaggcttccgtcatgaaggagttcaattgtcaccacgtggtgcgg
ttgctgggtgtggtgtctcagggccagccaacactggtcatcatggagctgatgacacga
ggagacctcaaaagctatctcaggtctctgcgaccggaaatagagaacaacccagccttt
gcccccccgagcctgagcaagatgatccagatggcgggcgagatcgcagatggcatggcg
tacctcaacgccaacaagttcgtccacagagacctggctgctcggaactgcatggtggcc
gaggacttcaccgtcaagatcggagactttggcatgacacgagacatctacgagactgac
tattaccgcaaaggagggaagggcctgctgcccgtgcgctggatgtcccccgagtccctc
aaggatggagtcttcactacccactctgatgtctggtccttcggagtcgtgctctgggag
attgctacgctggccgagcagccataccagggtttctccaacgagcaggtcctgcgtttt
gtcatggagggtggcctactggacaagccggacaactgccccgacatgctgtttgagctg
atgcgcatgtgctggcagtacaaccccaagatgcggccttccttcctggatatccttgga
agcgtcaaggacgagctcgagcccggcttccgtgaggtctccttctactacagcgacgac
aacaaggcgcctgaggctgaggccgaggccgaggccctggccctggcccaggcccaagcc
caggccgaggccgaggtcgaggacgaggacgacgagctggagctggagcccgaagacatg
gagagcgtgcccctggacccctctgccgccgccgccgccgccgtggccgccctcggcata
ccgctgcccgaccgacacaagcccgagaacgggccggggctgggggccatggtcctctgc
gccagctgcgaggagcagcggcgacggccctactcgcacatgaatgggggccgcaccgat
gagcgggccctgccgctgccccagtcctccacctgctga
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