Ochotona curzoniae (black-lipped pika): 121156804
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Entry
121156804 CDS
T11174
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00230
Purine metabolism
ocz00670
One carbon pool by folate
ocz01100
Metabolic pathways
ocz01523
Antifolate resistance
Module
ocz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121156804 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121156804 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121156804 (GART)
Enzymes [BR:
ocz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
121156804 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
121156804 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
121156804 (GART)
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GFIT
Other DBs
NCBI-GeneID:
121156804
NCBI-ProteinID:
XP_040836702
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Position
Unknown
AA seq
1045 aa
AA seq
DB search
MKSCLRIIPGLCTCCLPDCGLFCVQVSLSVGTHTAMTARVLVIGNGGREHALAWKLSQSH
HVQQVLVAPGNAGTACSGKISNTAISVDNHAALAQFCKHENIALVVVGPEAPLAAGVVES
LTSAGVRCFGPTAKAAQLESSKRFAKEFMDRHGIPTARWRAFTSPEEACHFILSADFPAL
VVKASGLAAGKGVIVAENKEAACKAVQEIMQEKSFGAAGETIVVEELLEGEEISCLCFSD
GKTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAPQVSKDLLLEIKNTVLQRAVDGMQQE
GTPYVGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLFEVIQSALDGLLCTSL
PAWLDDHTAVTIVMASQGYPGAYAKGVEITGFPEAQALGLQVFHAGTALQEGRVVTNGGR
VLAVTAIQETLSSALEEAKKGLTLLRFAGSIYRTDIGFRALAFLQRPRGLTYKDSGVDIA
AGNMLVKKIQPLAKATSRAGCDVALGDFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQL
CNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFACGKLDLKTTEAVVAGIAKACGKAGCA
LLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGVASSGLHSNGFS
LVRKIVAKSSLQYSAPAPAGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGG
LLENIPRVLPQKLGVDLDARSWKIPRIFSWLQQEGQLSEEEMARTFNCGVGAVLVVPKEH
TEPLLRDIRQRQEEAWVIGSVVARTKGSPCVKVKNLTEALQVDRSVLENSSLENHSPAHP
KKARVAVLISGTGSNLQALIDSTQQPHSASRIAVVISNKAGVAGLERAQRADIPTRVINH
KLYKDRVEFDNAIDQVLEEFSTDIVCLAGFMRILSGPFVRKWTGKMLNIHPSLLPSFKGA
NAHEQALEAGVTVSGCTVHFVSEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKVFP
AALELVATGAVQLGENGKICWAKGQ
NT seq
3138 nt
NT seq
+upstream
nt +downstream
nt
atgaagtcgtgcttgaggattattcctggactgtgtacgtgctgtcttcctgactgtggt
ttgttctgcgtgcaggtttcgttgtccgttggcactcacacagcaatgacagcccgagtt
ctggtcatcggcaacggaggcagggagcacgcgctggcctggaagctctcacagtcccat
catgtccagcaggtgttggttgccccaggaaatgcagggactgcctgctctgggaagatt
tccaacactgccatctcagttgacaaccacgctgcccttgcccagttctgcaaacacgag
aacattgcgttggtggtggttggacccgaggcacccctggccgccggggtcgttgagagc
ctgacatctgcgggggtgcgatgcttcggccccacagcaaaggcagctcaactggagtct
agcaagaggtttgccaaagagtttatggatcgacacggaatcccaactgcacgctggcga
gctttcaccagccctgaggaagcctgccacttcatcctgagtgcagacttccctgctttg
gttgtgaaggccagtggtcttgcagctgggaaaggagtcattgttgcagagaacaaagaa
gcagcctgcaaggctgtgcaggagatcatgcaggagaaaagctttggagcagctggagaa
acgattgttgttgaagaacttcttgaaggggaagagatttcttgtctctgcttcagtgat
gggaaaacggtggcccccatgcctccagcacaggaccacaagcgcttactagagggagat
catggtcccaatacagggggaatgggagcctactgtccagcacctcaggtttctaaggac
ttgttactagaaattaaaaatactgttcttcagagggcagtggatggcatgcagcaggag
ggcactccttacgtagggattttgtatgctggtataatgctcaccaaagatggcccaaaa
gttctggagtttaattgccgttttggtgatccagaatgccaagtgatcctcccactgctt
aaaagtgatctttttgaagtgattcagtccgccttagatggcctgctttgcacgtccctg
cctgcctggctagacgaccacaccgctgtaactatagtcatggcaagtcagggttatcct
ggagcctatgccaagggtgtggaaatcacggggtttcctgaggcccaggctctgggacta
caggtgttccatgcgggaactgccctccaggagggcagagtagtgacaaacgggggaaga
gttcttgctgtcacagccatccaggagactctcagctcagccctcgaggaagccaagaaa
ggactgactcttctgaggtttgcgggctccatttataggacggacattggcttccgtgcc
ctggccttcctccagcggcccagaggcctgacttacaaggactctggagtggacattgca
gctggaaacatgctggtgaaaaaaattcagccattagccaaagccacctctcgggcaggc
tgtgatgttgctcttggagatttcgctggtctttttgatttgaaagcagctggcttcaaa
gatcctcttctggcctccggaacagatggtgttggaacaaaactgaagattgctcagctc
tgcaataaacatgacaccattgggcaagacttggttgcgatgtgtgtgaatgacattctg
gcgcaaggcgcagagcccctcttcttcctggattacttcgcctgcgggaaactcgacctc
aagacaactgaagccgtcgttgctggcatcgccaaagcatgtgggaaagctgggtgtgct
ctccttggaggtgaaacagcagaaatgcctgacatgtatcctcccggagagtacgacctt
gctgggtttgctgttggtgccatggagcgggaccagaagctccctcatctagaaagaatc
actgaaggggatgttgttgttggcgtagcttcatctggtctccacagcaatggctttagc
cttgtgaggaagattgtggccaaatcttcactgcagtactctgcgccagcacctgctggt
tgtggtgaccagaccttaggggacctgcttttaactccaacaagaatctacagccattcg
ttgttacccgtcctccggtcaggtcatgtcaaggcttttgctcatattaccggtggagga
ttgctggaaaatatccccagagtcctgcctcagaaacttggtgtagatctagatgcccgg
agctggaagatccccaggatcttttcatggctgcagcaagaagggcagctctcggaggag
gagatggccaggacgtttaactgtggggttggagctgtacttgtggtaccaaaggagcac
acagagccacttctgagggacattcggcagcgccaggaggaagcctgggtgattggcagc
gtggttgcccgaactaaaggttccccttgtgtaaaagtcaagaatctgactgaagccttg
caagtggacaggtcagtgctggagaacagctccctggaaaatcattcccctgcccatcca
aaaaaggcaagagtggctgtcttgatatccggaacaggttccaacctacaggcactcata
gacagtactcagcagccacacagcgcctcgcgcatcgctgtcgtcatctccaacaaagcc
ggggtcgccgggctagagagggcacagagagctgacattcccaccagggtgattaatcat
aaattatacaaggatcgtgtagagtttgacaatgccattgaccaagttcttgaagaattc
tccacagacatagtctgtcttgcaggattcatgagaatactgtctgggccgtttgttagg
aaatggactgggaaaatgctcaacatccacccgtccttgctcccttccttcaagggtgca
aatgcacacgagcaggctctggaagctggggtcacagtcagcggctgcaccgtgcacttc
gtgtctgaggatgtagatgccggacaaattattctgcaagaagctgttccggtgaaaagg
ggtgacactgttgcaactctgtctgaaagagtaaagttagcagaacataaagtatttcct
gcagccctcgagctggtggccactggagctgtacagcttggagaaaatggcaagatttgt
tgggccaaagggcaataa
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