Ochotona curzoniae (black-lipped pika): 121160566
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Entry
121160566 CDS
T11174
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00230
Purine metabolism
ocz00670
One carbon pool by folate
ocz01100
Metabolic pathways
ocz01523
Antifolate resistance
Module
ocz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121160566 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121160566 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121160566 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ocz04147
]
121160566 (ATIC)
Enzymes [BR:
ocz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
121160566 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
121160566 (ATIC)
Exosome [BR:
ocz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
121160566 (ATIC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
121160566
NCBI-ProteinID:
XP_040842385
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPGQLAVLSVSDKTGLVDFARNLASFGLNLVASGGTAKTLRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARDIPEDNADMARLDFNLIRVVACNLYPFVQTVASPEVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAVVSTEMQASDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLRPKLPLTVLNGAPGFINL
CDALNAWQLVKELKDALGIPAAASFKHVSPAGAAVGIPLSEDEARVCMVHDLYQTLTAVA
TAYARARGADRMSSFGDFIALSDVCDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
SYCVLQMDASYKPDENEVRTLFGLRLSQKRNNGVVDRSLFSNVVTKNKELPESAIRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKA
GVKRAEISNAIDQYVTGTIGEDEDVLKWKALFEEVPAMLTEVEKKEWVDKLSGVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggctcccggccagctagccgtcttgagtgtctcggacaaaaccggtctcgtggatttt
gccagaaacttggcttcttttggcttgaatctcgtcgcctctggagggactgcgaaaact
cttagggatgctggtctggcggtcagggatgtctccgagctgacagggtttcctgagatg
ctgggagggcgtgtgaagaccttgcatcctgcagtacatgctggaatcctggctcgtgat
atcccagaagacaatgctgatatggccagacttgatttcaacctgataagagtcgttgcc
tgcaacctgtacccgtttgtgcagaccgtggcgtccccggaggtgacggtggaggaggcc
gtggagcagatcgatattggtggagtgaccctgctgagagctgcagcgaagaaccacgcc
cgagtgacagtggtgtgtgagccagaggactatgcggtggtgtccacggagatgcaggcc
tccgacagtaaggacacctccctggagacccgacgccagcttgccctgaaggcattcact
catacagcacagtatgatgaagccatttccgattacttccggaaacagtacagcaaaggc
atatcgcagatgcccctgaggtatgggatgaaccctcatcagactcctgcccagctctac
acactgaggcctaagctgcccctcactgttctcaatggagctcctgggttcataaacttg
tgcgatgctttgaatgcctggcagctagtgaaggaactcaaagatgcgttaggcattcca
gctgctgcctctttcaaacatgtcagccccgcaggtgccgcggtgggaattccgctgagt
gaagatgaggccagagtctgcatggtccacgatctctatcagaccctcacagctgtggca
accgcatacgccagagcaagaggggctgacaggatgtcttcatttggtgattttattgca
ctgtctgatgtttgtgatgtcccaactgcaaaaattatctccagagaggtgtctgatggc
attgttgccccagggtatgaggaagaagccttgaaaatcctgtctaagaagaagaatggg
agttactgcgttctccagatggatgcatcttacaaaccggatgaaaatgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcgttgacagatcactgttc
agcaacgttgtcaccaagaataaagaactgccagaatctgccatcagagacctcattgtg
gccaccatcgctgtcaagtacactcagtctaactcggtgtgctatgccaagaacgggcag
gtgattggcatcggtgcggggcagcagtcccggatacactgcacacgcctggcaggggat
aaggccaactactggtggcttcggcaccacccgcaggtgctctcaatgaagtttaaggcg
ggcgtgaagcgagcggagatctccaatgccatcgaccagtatgtgactggaaccatcggc
gaggatgaagacgtactcaagtggaaggctctctttgaagaagtccctgcaatgttaacg
gaggtcgaaaagaaggagtgggttgacaaactgagtggagtctctgtcagctctgatgcc
ttctttcccttcagggataatgtggatagagcgaaaaggagtggcgtggcgtacattgct
gctccgtccggttctgctgctgacaaagttgtcattgaggcttgtgatgaactaggaatc
atcctcgctcatacgaatcttcgcctcttccaccactga
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