Ochotona curzoniae (black-lipped pika): 121160806
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Entry
121160806 CDS
T11174
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00220
Arginine biosynthesis
ocz00330
Arginine and proline metabolism
ocz01100
Metabolic pathways
ocz04020
Calcium signaling pathway
ocz04081
Hormone signaling
ocz04145
Phagosome
ocz04371
Apelin signaling pathway
ocz04713
Circadian entrainment
ocz04730
Long-term depression
ocz04926
Relaxin signaling pathway
ocz04970
Salivary secretion
ocz05010
Alzheimer disease
ocz05014
Amyotrophic lateral sclerosis
ocz05022
Pathways of neurodegeneration - multiple diseases
ocz05410
Hypertrophic cardiomyopathy
ocz05412
Arrhythmogenic right ventricular cardiomyopathy
ocz05414
Dilated cardiomyopathy
ocz05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
121160806 (NOS1)
00330 Arginine and proline metabolism
121160806 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
121160806 (NOS1)
04020 Calcium signaling pathway
121160806 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
121160806 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
121160806 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
121160806 (NOS1)
09154 Digestive system
04970 Salivary secretion
121160806 (NOS1)
09156 Nervous system
04730 Long-term depression
121160806 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
121160806 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
121160806 (NOS1)
05014 Amyotrophic lateral sclerosis
121160806 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
121160806 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
121160806 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
121160806 (NOS1)
05414 Dilated cardiomyopathy
121160806 (NOS1)
05416 Viral myocarditis
121160806 (NOS1)
Enzymes [BR:
ocz01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
121160806 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
121160806
NCBI-ProteinID:
XP_040842807
LinkDB
All DBs
Position
Unknown
AA seq
1475 aa
AA seq
DB search
MSSAEAPGTTGTMEEPVCGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIR
GGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLE
TTFTGDGTPKTIRVTQPLGAPTKAVDLSHQLPASKEQPRAVDGATGPGNGPQHAQASSPS
HANGLAPRSSSQDTAKKGGKGGPPGSGEKNELLKEIEPVLTLLTGGSKEVNGGAPPKVET
RDTGVQVDRDLDGKSHKPLPLGTENDRVLGDLWGKDNAPVVLNNPYPEKEQPPASGKQSP
TKNGSPSKCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSQHTRRPEDV
RTKEQLFPLAKEFIDQYYSSIKRSGSKAHMDRLEEVNKEIEATSTYQLKDTELIYGAKHA
WRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDG
KHDFRVWNSQLIRYAGYKQPDGSILGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANG
NDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWY
MGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTI
VDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPCFEYQP
DPWSTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQA
YAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEM
RHPNSVQEERKYPEPLRFFPRKGPSLPHGNTDVHRLAAVRDSQYRSYKVRFNSVSSYSDS
RKSSGDGSDVRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKM
REGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYV
AEAPGLTQGLSNVHKKRVSAARLLSRQNLQSPNSSRATIFVRLHTNGNQELQYQPGDHLG
VFPGNHEDLVNALIERLEDAPPANQMVKVELLEERSTALGVISNWKDEPRLPPCTIFQAF
KYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFP
SIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPIHHGVCSSW
LNRIPADEVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNP
CPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAEP
VYRALKEQGGHIYVCGDVTMAADVLKAVQRIMTQQGKLSAEDAGVFVSRLKDDNRYHEDI
FGVTLRTYEVTNRLRSESIAFNEESKKDTDEVFSS
NT seq
4428 nt
NT seq
+upstream
nt +downstream
nt
atgtcttcagccgaggcccctgggacaacaggcaccatggaggagcctgtgtgtggtgtt
cagcagatccaacccaatgtcatttccgtccgcctcttcaagcgcaaggtggggggcctg
gggttcctggtgaaggagcgtgtcagcaagccccccgtgatcatctcggacctgattcgt
ggcggggctgccgagcagagtggcctcatccaggctggggacattattctcgccgtcaat
ggcagacccctagtggacctgagctatgacagtgccctggaggtactcaggggcattgcc
tctgagacccacgtggtcctcatcctgagaggcccagagggcttcaccacacacctggag
accaccttcactggggacgggacccccaagaccatccgtgtaacacaacccctgggcgct
cccaccaaagccgtggatctgtcgcaccagctgccagccagcaaggagcagccacgggca
gtggatggggccacgggtcccggcaatggaccccaacatgcccaagccagctcaccctcc
catgccaatggcctggcccctagatcctcaagccaggacactgccaagaagggtggcaag
ggtggccctccaggcagtggggagaagaatgagcttctgaaagagatcgagccagtgctg
acccttctcaccggtgggagcaaagaggtcaatggaggagctcctcccaaggtggagacg
agagacacgggcgtccaggtagacagagacttggacggcaagtcacataagcccctgcct
cttggcacggagaatgaccgagtcctcggtgacctgtgggggaaggacaatgcacctgtt
gtcctcaacaacccatatccagagaaggagcagccccctgcctcaggaaagcagtccccc
accaagaatggcagcccctccaagtgcccccgcttcctcaaggtcaagaactgggagaca
gatgtggtcctcacagataccctccaccttaagagcacactggaaactgggtgcaccgag
cacatttgcatgggatccatcatgttgccgtctcagcacacacggaggcctgaagacgtc
cgcacaaaagaacagctcttccctcttgccaaggagttcatcgatcagtactactcatcc
attaaaagatctggctccaaagcccacatggacagattggaagaagtaaataaagagatt
gaggccaccagcacctaccagctcaaagacacagagctcatttatggggccaagcatgcc
tggcgtaacgcctcccgctgcgtgggcaggatccagtggtccaagctgcaggtgtttgat
gcccgcgactgcaccacggctcacggcatgtttaactacatctgcaaccacatcaagtat
gccaccaacaaggggaacctcaggtcggccatcaccatatttccccagaggacagacggc
aagcatgacttccgcgtctggaattcccagctcatccgctatgctggctacaagcaacct
gatggctccatcttgggggacccagccaacgtacagttcacagagatctgcatccagcag
ggctggaaacccccaaggggccgcttcgacgtcctgccgctcctgctgcaagccaacggc
aatgatcctgagctcttccaaatcccaccagaactggtgctcgaagtgcctatcaggcac
cccaagtttgagtggttcaaggacctggggcttaagtggtatgggctccctgctgtgtcc
aatatgctcctggagattggtggcctagagttcagcgcctgtcccttcagcggctggtac
atgggcacagagatcggcgtccgtgactactgtgacaactcccgctacaacattctggag
gaagtggccaagaagatgaacttggatatgaggaagacgtcctcgctgtggaaggaccag
gcactggtggagatcaacattgctgttctctacagcttccagagcgacaaggtgaccatc
gtagaccaccactctgccactgaatccttcatcaagcacatggaaaatgagtaccgctgt
cgagggggctgccccgccgactgggtgtggattgtgccccccatgtctggcagcatcacc
cctgtcttccaccaggagatgctcaactatcggctcaccccctgcttcgaataccagcct
gatccttggagcacccatgtgtggaaaggcaccaatgggacccctacgaagcggcgagcc
atcggcttcaagaaactggcagaagccgtcaagttttcagccaagctgatgggacaagca
atggccaagagggtcaaagcaaccatcctgtatgccacagagacgggcaagtcacaagcc
tatgccaaaaccctgtgtgaaatcttcaagcacgcctttgatgccaaggtgatgtccatg
gaagaatatgacattgtacatctggaacatgaaactctggtcctggtggtgaccagcacc
tttggcaacggagacccccctgaaaatggagagaaattcggctgcgctttgatggaaatg
aggcaccccaactctgtgcaggaggaaaggaagtacccggaacccttgcgtttctttccc
cgtaaagggccttccctccctcatggtaacactgacgtccaccgtctggctgcagtccgt
gacagtcagtacaggagctacaaggtccgattcaatagtgtctcctcctactcagactct
cgtaagtcatcaggcgatggctccgacgtcagagacaactttgagagcactggacccctg
gctaatgtgaggttttctgtgtttggcctgggttcacgggcataccctcacttctgtgct
tttggacatgctgtggacacactcctggaagagctgggaggggagaggatcctgaagatg
agagaaggagatgagctctgtgggcaggaggaggctttccggacttgggccaagaaggtc
ttcaaggcagcttgtgatgtgttctgcgtgggcgatgacgttaatatcgagaaggcaaac
aattccctgatcagcaatgaccgcagctggaagaggaacaagttccgcctcacttacgtg
gctgaagcccccgggcttacacaaggcctttccaatgtccacaaaaagcgagtctctgct
gcgcgactcctcagccgccaaaacctgcagagtcctaactccagccgagccactatcttt
gtgcgcctacacaccaacgggaaccaggagctgcagtaccaacctggggaccacctcggg
gtcttcccaggcaaccatgaagacctcgtgaatgccctgatcgaacggctggaagacgcg
ccccccgccaaccagatggtcaaagtggaactgctggaggagcgtagcaccgctctaggc
gtcatcagtaactggaaggatgaaccccgcctgcccccatgcaccatcttccaggccttc
aagtactacctggacatcaccacgccacccacgcccctgcagctacagcagttcgcctcc
ctggcaaccaacgagaaagagaaacagcggctgttggtcctcagcaagggtctgcaggaa
tacgaggagtggaaatggggcaagaaccccaccatcgtggaggtgctggaggaattccca
tctatccagatgccggccaccttgctcctgacccagctgtcccttctgcagcctcgctac
tactccatcagctcctccccagacatgtacccggacgaggtgcacctcacggtagccatc
gtgtcctaccacacccgagatggagaaggaccaattcatcatggtgtgtgctcctcttgg
ctcaaccggatccctgctgatgaagtggttccctgctttgtgagaggtgcacccagcttc
cacctgcccagaaatccccaagtcccctgcatcctagtgggcccgggtaccggcattgcg
ccattccgcagcttctggcagcagcggcagtttgacatccaacacaaaggaatgaacccc
tgtcccatggtcctagtgtttgggtgccggcagtccaagatagatcacatttacagggag
gagaccctccaggccaaaaacaagggtgtcttcagagaactgtacacggcctactcccgg
gagcccgacaagccaaagaagtacgtgcaggacatcctgcaggagcagttggcagagccc
gtgtaccgggccctgaaggagcagggaggccacatctacgtctgcggggacgtgaccatg
gccgccgacgtgctcaaggctgtgcagcgcatcatgacacaacaggggaagctctcggcc
gaggacgccggcgtgttcgtcagcaggctgaaggatgacaaccggtaccatgaggacatt
tttggagtcaccctgcgcacgtatgaagtgaccaaccgccttagatccgagtccatcgcc
ttcaacgaggagagcaaaaaagacacggatgaggttttcagctcctaa
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integrated database retrieval system
