Ochotona curzoniae (black-lipped pika): 121163191
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Entry
121163191 CDS
T11174
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00310
Lysine degradation
ocz01100
Metabolic pathways
ocz05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
121163191 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
121163191 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ocz03036
]
121163191 (DOT1L)
Enzymes [BR:
ocz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
121163191 (DOT1L)
Chromosome and associated proteins [BR:
ocz03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
121163191 (DOT1L)
HMT complexes
Dot1-containing complex
121163191 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
121163191
NCBI-ProteinID:
XP_040846465
LinkDB
All DBs
Position
Unknown
AA seq
1697 aa
AA seq
DB search
MGDKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMSEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDSKSNATTPTKAP
EGKAAGPATTATTTGATAAEAPADFGAEDEKAGVTTVKKASPSKARKKKLNRKGRKMAGR
RRGRPKKLSAVDPERKPRKSRAVLDALHTPAAPPTAPPSPQEPYRSPHSPFYQLPPGAQR
LPPNPLLTAPTPPALQKLLESFRVQYLQFLAYTKTPQYKANLQQLLDQEKEKKAQLLGTA
RQLFSHCQAQKEEIRRLFQQKLDELGVKALTYDDLIQAQKEICAHNQQLREQSEQLERDN
SQLRSQSLQLLKARCEELRLDWATLSLEKLLKEKQALKSQISEKQRRCLELQISIVELEK
SQRQQELLQLKSCVLPDDALPLHLRAKGPLGRELEAEPSRLHLELDCAKLSLPHLSSMSP
ELSMNGHAASYEPCGAPSRPSSKQNTPQYLSSPLDQEVVPCTPGLSGRPRLEKLSALALP
ECTRLSPASVVLRRHPGQEHPGPARAAASEAAPRVEHAKENGLPYPSPCLPSGTKLSPQD
PRPPSPGPMPLLTEKSSEKGVKERAYSSSGDTITSLPISIPLSTVQPNKLPVSIPLASVV
LPSRAEKVGRSTPSPVSALDKQIGANTHSAGSKGLGLAPTGFAYAGSVAITGPLGGSPAP
LVPGGESAAFDESCSSSSLFVAVGSRSTTPQHPPLLGQPRTSGPASPAHQLAASPRLAGA
AQGTVPDPSKGELPCDTGFSDPESEAKRRSVFTISSGAGSAKQSPSNKHSPLTSGSRGDS
GQGHGQDRRKRGRRKRASAGTPSLGVSPKRRALPSVVGLFTPSSGSPLNLSSMVSNINQP
LEITAISSPENSLKSSPTPYQDHDQPPVLKKERPLGPPNGAHYSPLTSDEEPGSEDEPGS
ARIERKIATISLDSKSPPKSLENGGGLAGRKLAPASEPVNSSKWKSTFSPISDVSLTKSA
DSPLQASSASSQASLFAFRPALDEPGAAEPKLAAHPRKSFASSLAGADGHSPGAHPSNSF
ALGPGLASELGLHGFSDGASLAHKVPSEANPFFTKRQLEGLGGLKGEGGPAKEPGEPGLS
LCGPMDKAGPPHGSRASKGRDRDHDGKNGHNLFISAAAAPPGGLLGGPGLVTAAPAAGSS
APGGQAHRPFLGTFGPGPQFMGPMSLQANLSSVAGSSVLQSLFGSVPAAAGLVHVSSAAA
RLTNSHTMGSFSGVAGGTVGGVFNHAVPPASAHLFGASVGSGAVCGSAPLGLSPLQASSL
QAEIRPPPPPAPPLAPAPPPPNVALPPAPTLLTANLDPVLLQSLTPVPVNINHVFLAPAS
AASLSPTNPSLSVKLTPLSHKVSHPPFSVHPQPLPRLALAQTVPGIPQASSTGAPAVWVS
LGMPPPYAAHLSGRKPR
NT seq
5094 nt
NT seq
+upstream
nt +downstream
nt
atgggcgacaagctggagctgaggctcaagtcacccgtcggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagatcatcgagacc
atccggtgggtctgcgaggagatcccagacctcaagctcgctatggagaactacgtactc
atcgactacgacaccaaaagctttgagagcatgcagaggctgtgtgacaagtacaaccgt
gccatcgacagcattcaccagctgtggaagggcaccacccagcccatgaagctcaacacg
cggccgtccaatgggctgctgcggcacatcctgcagcaggtgtacaaccactcggtcacc
gaccccgaaaagctcaacaactacgagcccttctccccggaagtgtacggcgaaacctcc
tttgacctggtggcccagatgattgacgagatcaagatgagtgaggatgacctgttcgtg
gacttgggcagcggtgtgggccaggttgtgctacaggtcgccgcggccaccaactgtaag
catcactacggcgtggagaaagcggacatcccggccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaagaagcatgcagaatacacactggaaaga
ggcgattttctctcagaagagtggagggagcgcattgccaacacgagtgtcatctttgtg
aataactttgcctttggtcccgaggtggaccaccagctgaaggagcgcttcgccaacatg
aaggaaggtggcaggatcgtgtcctcaaagcccttcgcgcctttgaacttcaggatcaac
agcaggaacctgagtgacatcggcactatcatgcgcgtggtggagttgtcccccctgaag
ggctccgtgtcgtggacagggaagccagtgtcgtactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtttgaaaaacccaaaactcagggaggaacaggaggcc
gctcggcgccgacagcagcgggacagcaagagcaacgctaccacccccaccaaggccccc
gaggggaaggcggctggcccagcgacgacagcaacaacgacaggggctactgcagcggag
gcccctgcggactttggtgctgaggatgagaaggcaggggtgaccactgtcaagaaggcc
tctccctccaaggcccgcaagaagaagctgaacaggaagggccgcaagatggccggccgg
cggcgtgggcgccccaaaaagctgagcgccgtggaccccgagcgcaaaccccgcaagagc
cgcgccgtgttggatgccctgcacaccccggccgcacctcccaccgcccctccctctccc
caggagccatataggtcccctcacagcccgttctaccagctacctccaggtgcgcagcga
ctacccccaaacccgctgctcacggcgcccacccctcccgcgctgcagaagctgctagag
tccttcagggtccagtacctgcagttcctggcctacaccaagaccccgcagtacaaggcc
aacctgcagcagctgctggaccaggagaaggagaagaaggcccagctgctgggcacggcc
cgccaactcttcagccactgccaggcccagaaggaagagatccgtaggctcttccagcag
aagctggacgagctgggggtgaaagccctgacgtatgatgacctgatccaagcccagaaa
gagatctgcgctcacaaccagcagctgcgggagcagtcggagcagctggagagagacaac
agccagctccgcagccagagcctccagctgctgaaagcccgctgcgaggagctgcggctg
gactgggccacactgtcactggagaagctgctgaaggagaagcaggccctcaagagtcag
atctcagagaagcagcggcgctgcctggagctgcagatcagcatcgtggagctggagaag
agccagcggcaacaggagctactgcaactcaagtcgtgcgtgctgcccgacgacgctctc
cccctgcacctgcgggccaagggcccgctgggccgcgagctggaggccgagcccagccgc
ctgcatctggagctcgactgtgccaagctctcgctgcctcacctgagcagcatgagccct
gagctgtccatgaacggccatgcggccagttacgaaccgtgtggcgccccgagccggcct
tcgtccaagcagaacacgcctcagtacctgtcctcgcctctggaccaggaggtggtaccc
tgcacccccggcctcagcggccggccccggctcgaaaagctgtcagcgctggccctacct
gagtgcacaaggctgtccccagccagcgtggtgctgcggaggcacccaggccaggagcac
ccggggccggccagggctgctgccagtgaggccgctccaagggtggaacatgccaaggag
aatggcctcccctaccccagcccctgcctgcccagcggaaccaagctgagccctcaggac
ccacggccgccatcgcctgggcccatgccactcctgactgagaagagcagtgagaagggc
gtgaaggagcgagcctacagcagcagcggggacaccatcaccagcctgcccatcagcatc
ccactgagcaccgtgcagcccaacaagctgcccgtcagcatccccctggccagcgtggtg
ttgcccagccgcgccgagaaggtgggtaggagcacccccagtcccgtgtcggcactcgac
aagcagattggtgctaatacccacagcgcggggagtaaaggcctgggcctggccccgaca
ggttttgcctatgcgggctcggtggccatcacagggcccttgggcgggagcccagccccc
ctggtacccggaggagagtccgctgccttcgacgagtcctgcagctccagcagcctcttc
gtggctgtgggctcccgcagtaccaccccacagcatccgcccctgctcggccagccccgc
acctctggtcctgcctctcccgcccaccagcttgctgccagtccccggcttgctggggct
gcccagggcactgtccccgaccccagcaagggagaactcccctgtgacaccggcttctca
gaccccgagagcgaagccaagaggaggagcgtgttcaccatctcgtccggcgcgggcagt
gccaagcagtcgccctccaacaagcacagccccttgacctccggctcccgtggggacagc
ggccagggccacgggcaggacaggcgcaaacgtggccgcaggaagcgcgcctcagctggg
acccccagcctgggggtgtcccccaagcgccgggcactgccatccgtcgtggggctcttc
accccgtcctcagggtcccccctcaacctcagctccatggtcagcaacatcaaccagccc
ttggagatcacggccatctcgtcccccgagaattccctaaagagctccccgaccccctac
caggaccacgaccagccccccgtgctcaagaaggagcggcccctgggcccccccaatgga
gcccactactccccgttgacatcggacgaggagccgggctccgaggatgaacctgggagt
gctcgaattgagaggaagattgcgacaatctccttagatagcaaatctcccccgaaaagc
ttggagaatggtggtggtctggcggggaggaagctggctcccgccagcgagccggtcaac
agcagcaagtggaaatccaccttctcgcccatctccgatgtgagcctgaccaagtcggcc
gacagcccactgcaggccagctctgcctcaagccaggcctccctgtttgccttccgcccg
gccctggatgagccaggggccgctgagcccaagttggctgcccacccaaggaagagcttc
gccagctccttggcaggggccgacggacacagcccaggggcccacccttccaacagcttc
gcactgggcccgggcctggcctcggagctcggcctgcatggtttcagcgatggtgcttcc
cttgcccacaaggtcccctcggaggccaatcctttcttcaccaagaggcagctggaaggc
ctgggcggcctcaagggcgagggcggcccggccaaggagccgggcgagccgggcctgtcc
ctgtgcgggcccatggacaaggccggccccccccacggcagcagggccagcaaggggcgg
gaccgcgaccacgacggcaagaacggccacaacctcttcatctcggcagcggcggcgccc
cccggtggcctcctcggcggccctggcctcgtgacggcagctccggcagcaggcagctcg
gcacccggcggccaggcgcaccgccccttcctgggtacttttgggcctgggccacagttc
atgggccccatgtccctgcaggccaacctgagctcggtggccggctcgtccgtgctccag
tccttgtttggctccgtgccggccgccgcgggcctggtgcacgtgtcctccgctgcggcc
agactgaccaactcccacactatgggcagcttctccggggtggcaggcggaaccgtcgga
ggtgtctttaaccacgcggtgcctcccgcctctgctcatctgtttggagccagtgtcggc
agtggggctgtgtgtggcagcgccccgctgggcctgagcccgctgcaggcctcctccttg
caggccgagattcggcctccccctccgccagccccgcccctggcccccgccccgccgccc
cctaacgtggccttgcctcccgccccgacgctgctgaccgctaacctggaccccgtgctg
ctgcagagcctcacgcccgtccctgtaaacattaaccacgtcttcctagctcctgcctcc
gctgcttctctgtctcccactaacccctctctctctgtcaagctcaccccactctcgcac
aaggtctcccacccgcccttctcggtgcacccgcagcccctgccccggctggccttggca
cagaccgtgcccggcatcccgcaggccagctccacgggcgcgcccgctgtgtgggtttct
cttggcatgccgcctccttatgccgcgcacctttcggggcgtaagccgcgctaa
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integrated database retrieval system
