KEGG   Ochotona curzoniae (black-lipped pika): 121168838
Entry
121168838         CDS       T11174                                 
Symbol
ATP1A1
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-1 isoform X1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
ocz  Ochotona curzoniae (black-lipped pika)
Pathway
ocz04022  cGMP-PKG signaling pathway
ocz04024  cAMP signaling pathway
ocz04260  Cardiac muscle contraction
ocz04261  Adrenergic signaling in cardiomyocytes
ocz04820  Cytoskeleton in muscle cells
ocz04911  Insulin secretion
ocz04918  Thyroid hormone synthesis
ocz04919  Thyroid hormone signaling pathway
ocz04925  Aldosterone synthesis and secretion
ocz04960  Aldosterone-regulated sodium reabsorption
ocz04961  Endocrine and other factor-regulated calcium reabsorption
ocz04964  Proximal tubule bicarbonate reclamation
ocz04970  Salivary secretion
ocz04971  Gastric acid secretion
ocz04972  Pancreatic secretion
ocz04973  Carbohydrate digestion and absorption
ocz04974  Protein digestion and absorption
ocz04976  Bile secretion
ocz04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:ocz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    121168838 (ATP1A1)
   04022 cGMP-PKG signaling pathway
    121168838 (ATP1A1)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    121168838 (ATP1A1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    121168838 (ATP1A1)
   04918 Thyroid hormone synthesis
    121168838 (ATP1A1)
   04919 Thyroid hormone signaling pathway
    121168838 (ATP1A1)
   04925 Aldosterone synthesis and secretion
    121168838 (ATP1A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    121168838 (ATP1A1)
   04261 Adrenergic signaling in cardiomyocytes
    121168838 (ATP1A1)
  09154 Digestive system
   04970 Salivary secretion
    121168838 (ATP1A1)
   04971 Gastric acid secretion
    121168838 (ATP1A1)
   04972 Pancreatic secretion
    121168838 (ATP1A1)
   04976 Bile secretion
    121168838 (ATP1A1)
   04973 Carbohydrate digestion and absorption
    121168838 (ATP1A1)
   04974 Protein digestion and absorption
    121168838 (ATP1A1)
   04978 Mineral absorption
    121168838 (ATP1A1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    121168838 (ATP1A1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    121168838 (ATP1A1)
   04964 Proximal tubule bicarbonate reclamation
    121168838 (ATP1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ocz04147]
    121168838 (ATP1A1)
Enzymes [BR:ocz01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     121168838 (ATP1A1)
Exosome [BR:ocz04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   121168838 (ATP1A1)
  Exosomal proteins of other body fluids (saliva and urine)
   121168838 (ATP1A1)
  Exosomal proteins of colorectal cancer cells
   121168838 (ATP1A1)
  Exosomal proteins of bladder cancer cells
   121168838 (ATP1A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 DUF1290 HAD
Other DBs
NCBI-GeneID: 121168838
NCBI-ProteinID: XP_040855182
LinkDB
Position
Unknown
AA seq 1023 aa
MGKGVGRDKYEPAAVSEHGDKKGKRAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLS
RGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAHGIRAA
TEEDFDNDNLYLGVVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKLSI
NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR
NIAFFSTNCVEGTARGIVIYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV
FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN
LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA
LSRIAGLCNRAVFQANQENVPILKRAVAGDASESALLKCIELCCGSVKEMRERYTKIVEI
PFNSTNKYQLSIHKNVTPNEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN
AYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDEVNFPVDNLCFIGLISMIDPPRAAVP
DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA
KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN
DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL
TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK
TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRVDWDDRWINDVED
SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFE
ETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEIRKLIIRRRPGGWVEKE
TYY
NT seq 3072 nt   +upstreamnt  +downstreamnt
atggggaagggggtcggacgtgataaatatgaacctgccgccgtttccgaacatggcgat
aaaaagggcaagagggccaagaaggagagggacatggatgagctgaagaaagaagtttct
atggatgaccataagctaagccttgatgaactgcatcggaaatacggcacagacctgagc
cggggcttgacaactgctcgagctgctgagatcctggcccgggacggccccaatgccctc
actccccctcccaccactccagaatgggtgaagttctgccggcaactgtttgggggcttc
tctatgctactgtggattggagcagttctttgtttcttggctcatggcatccgagctgcc
acggaggaggattttgacaacgataatctgtaccttggagtggtgctggcagctgttgtc
atcataactggctgtttctcctactatcaagaagcgaaaagttcaaagatcatggaatcc
ttcaaaaacatggttcctcagcaagccctggtaattcggaatggtgagaagttaagcatc
aacgcggaggaagtggtagttggagacctggtggaagtaaaggggggtgaccgcatccct
gctgacctcaggatcatctcggcgaatggctgcaaggtggataactcctcgctcactggg
gagtcagaaccccagacaaggtctccagatttcacaaacgaaaacccgctggagacgagg
aacatcgccttcttctccaccaactgcgttgaaggcactgcacgtggcattgttatatac
acgggagatcgcactgtgatgggaagaattgccacacttgcctctggcctggaagggggc
cagacacccattgctgcggaaattgaacattttatccacatcatcactggtgtggctgtg
ttcctgggcgtgtctttcttcattctttccctgatccttgaatacacctggcttgaggcc
gtcatcttcctcatcggcatcatcgtagccaacgtgccggaaggccttctggctactgtc
acggtgtgtctgacgcttactgcaaagcgcatggcacggaaaaactgcttggtgaagaac
ttggaagcggtggagaccttggggtccacatccaccatctgctcagataaaactggaact
ctaacccagaaccggatgacggtggctcacatgtggtttgacaatcagatccacgaagct
gacacaacagaaaaccagagcggtgtctcgttcgacaagacatccgccacctggctcgct
ttgtccagaatcgcaggtctctgtaacagggcggtgtttcaggctaaccaggaaaacgta
cctattcttaagcgagcagttgcaggcgatgcatctgaatcggcactcctgaaatgcatc
gagctgtgctgtggttccgtgaaggagatgagggagagatacaccaaaatcgtcgagata
cccttcaactccaccaacaaataccagctgtccattcacaagaatgtcactcccaatgag
ccacggcacctgctggtgatgaagggtgctccggagaggatccttgaccggtgcagctct
atcctcctccatggcaaggagcagcccctggacgaggagctgaaggacgcctttcagaat
gcctacctggagctggggggcctcggcgagcgagtgctagggttctgccacctccttctg
ccagatgagcagtttcccgaagggttccagtttgacacagatgaagtgaactttcctgtg
gataacctgtgctttattgggctcatctccatgatcgaccctccccgagctgccgtcccc
gatgctgtgggcaagtgccgtagcgctggaattaaggtcatcatggtcacaggagatcat
ccaatcacagccaaagccattgccaaaggtgtaggcatcatctctgaaggcaacgagacc
gtggaagacattgctgcccgcctcaacatcccagtgagccaggtgaaccccagagacgcc
aaggcctgcgtcgtgcatggcagtgacctgaaggacatgacctctgagcagctggatgac
atcctgaagtaccacacagagatcgtgtttgcccggacctcgccacaacagaagctcatc
atcgtggaaggctgccagagacagggtgctattgtggctgtcactggtgatggtgtcaat
gactcaccggcgctgaagaaggcagacattggagtggccatgggcattgcaggctcagac
gtgtccaagcaggccgcggacatgatccttttggacgacaactttgcttccattgtgaca
ggagtagaggaaggtcgtctgatcttcgataacttgaagaaatccattgcatacaccctg
accagtaacattccagagatcacccccttcctgatatttattattgcaaacattccacta
ccactggggaccgtcaccatcctctgcatcgacttgggcactgacatggttcctgccatc
tccctggcttatgaacaggcggagagtgacatcatgaagaggcagcccagaaaccccaaa
acagacaagctggtgaatgagcggctcatcagcatggcctacgggcagatcggtatgatc
caggccctcggaggcttcttcacatacttcgtgattctcgctgagaatggcttcctcccc
ttccacctattgggcatccgagtggactgggatgaccgctggatcaacgacgtggaagat
agctatgggcagcagtggacctatgagcagaggaagatcgtggagttcacctgccacacg
gccttctttgtcagcattgtggtggtgcagtgggctgacttggtcatctgcaagaccagg
aggaactcagttttccagcaggggatgaagaacaagatcttgatcttcggcctctttgaa
gagacagccctggctgccttcctctcctactgccccggcatgggcgtcgccctgaggatg
tatcctctcaaacctacctggtggttctgtgccttcccctactctcttctcatcttcgtg
tacgatgaaatcagaaaactcatcatcaggcgacgtcctggcggctgggtggagaaggaa
acctactactag

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