Ochotona curzoniae (black-lipped pika): 121169917
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Entry
121169917 CDS
T11174
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
121169917 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ocz03032
]
121169917 (TOP2A)
03036 Chromosome and associated proteins [BR:
ocz03036
]
121169917 (TOP2A)
Enzymes [BR:
ocz01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
121169917 (TOP2A)
DNA replication proteins [BR:
ocz03032
]
Eukaryotic type
DNA Topoisomerases
121169917 (TOP2A)
Chromosome and associated proteins [BR:
ocz03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
121169917 (TOP2A)
Centrosome formation proteins
Centriole proteins
121169917 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
121169917
NCBI-ProteinID:
XP_040856695
LinkDB
All DBs
Position
Unknown
AA seq
1529 aa
AA seq
DB search
MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKSFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNRLPIKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLADVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKSFGSTCPLSEKFMKAAMGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGSRNSAECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQELAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQSTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVRFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTALDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDTEKEPERSDSAADSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELETLKRKGPSDLWKEDLAAFIEELEAVEAKEKLDEQAGLPGKGGKA
KGKKAQVAEVLPSPRGQRVIPRVTSEMKAEAEKKIRKKIKSENTEGSPKEDGVEAEDLKQ
RLEKKQKREPGTKAKKQTTLPFKPVKKAKKRNPWSDSESDMSSNESNFDVPPREVEPRRA
AAKTKFTMDLDSDDDFSDFNEKTQDDDDFVSSPADLPKTKTSPKHTDKELKPQQGAMSVA
PPDSDTEGSAPLAAGAPDETEAVKPVPKTNVAMKKTTTKTLSSTSITGPKKRGPPKGTKK
NPAPKADVPQKPEAPKATKNPRKRKPSMSDESDSNFEEVVSKAVASKKSKGDSDNFHLDL
DSAVAPRAKSSRAKKPIKYLEESDEEDLF
NT seq
4590 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactacagcccgtcaatgaaaatatgcaagtgaacaaaataaagaaa
aatgaagatgctaagaaaagactgtctattgaaaggatctatcagaagaaaacgcaactg
gaacatattttgctgcgtccagatacctacattggctctgtagagttagtgacccagcaa
atgtgggtgtatgatgaagatgttggtatgaactacagggaagtcacttttgttcccggt
ttgtacaaaatctttgatgagattctcgttaatgctgcggacaacaagcagagggatcca
aaaatgtcttgcatcagagtcacaattgatcccgaaaacaatttaattagcatatggaat
aatggcaaaggtattcctgttgttgaacacaaagttgagaagatgtatgttccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtgacaggt
ggtcgaaacggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagctagcagagaatataagaaaatgtttaaacagacgtggatggataacatgggaaga
gctggtgaaatggaactcaagtcctttagtggagaagattatacgtgtatcaccttccag
cctgatttgtccaagtttaaaatgcaaagcctggacaaagatattgttgccctgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtcttccttaatggaaat
aggctaccaataaaaggattccgtagctatgtggatatgtatttgaaggataaagtagat
gaaactggcaacccactgaaagtcatacatgagcaagtgaaccacagatgggaagtgtgt
ctgacaatgagtgaaaaaggcttccagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgtcgattacgtagccgatcagattgtgacaaaacttgctgatgtt
gtaaagaagaagaacaaaggcggtgttgcagtcaaagcacaccaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagccaagagctttgggtccacttgcccgttgagtgaaaaattcatgaaa
gctgcaatgggctgtggtatcgtagaaagcatactgaattgggtgaaatttaaggctcaa
gtccagttaaacaaaaagtgttcagctgttaaacataacagaatcaagggaattcccaag
ctggatgatgccaatgatgcagggagccgaaactctgctgagtgtacacttatcctgacg
gagggagactcagccaaaactttagctgtttcaggccttggtgttgttggaagagacaaa
tatggggtcttcccccttagaggaaaaatactcaatgttcgagaagcttctcataagcag
attatggaaaatgctgaaattaacaatattatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattaaagactcttcgttatggaaagataatgattatgacg
gatcaggaccaagacggttcccatatcaaaggcttgctgattaatttcatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaattcatcactcctattgtaaaggtg
tctaaaaacaagcaagaattggcattctacagccttcctgaatttgaagaatggaagagt
tctactccaaatcataagaagtggaaagtcaagtattacaaaggtttgggtactagcaca
tcaaaggaagctaaagaatactttgcagatatgaagagacatcgtatccaattcaagtac
tctggtcctgaggatgatgctgctattagccttgcctttagcaaaaaacaaatagatgat
cggaaggaatggttaactcatttcatggaggatagaagacagcgaaagttacttggcctt
cctgaggattacttgtatggacaaagtaccacatatctgacatacaatgacttcataaac
aaagaacttatcctgttctccaattctgataacgagagatctattccatctatggtagac
ggtttgaaaccgggccagagaaaggttttgtttacttgtttcaaacggaatgacaagcga
gaagtgaaggttgcccagttggctgggtcggtggcagaaatgtcctcttaccatcatggt
gagatgtcgttaatgatgaccattatcaatttggctcagaattttgtgggtagcaacaat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gccagtcctcgatacatcttcacaatgcttagtcctttggctcggttattatttccacca
aaagatgatcatacattaaaatttctgtatgatgacaaccagcgagttgagcctgaatgg
tacattcccattatacccatggtgttgataaatggagcggaaggaattggtactgggtgg
tcctgcaaaatccccaactttgacattcgtgaagttgtgaataacatcagacgtttaatg
gatggagaagaacctttgccgatgcttccgagttacaagaacttcaagggtactattgaa
gagctggctccgaatcagtatgttattagtggtgaagtagctattcttaattctacaacc
attgaaatctcagagcttcccattagaacatggacccagacgtataaagaacaggttcta
gaacccatgttgaatggcaccgagaagacgccccctctgataacggactacagggagtat
cacacagacaccactgtgaggttcgttgtgaagatgactgaagaaaagctggcagaggca
gaaagagttgggttacacaaagtcttcaaacttcaaacgagtctcacctgtaactctatg
gtgctttttgaccatgtaggctgtttgaagaaatatgacacagcgttggatattctaaga
gacttctttgaactcagacttaagtattacggcttaagaaaagaatggcttctgggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgttttatcttggagaaaatagac
ggcaaaataatcattgaaaataagcctaagaaggaattaattaaagttctgatccagagg
ggatatgactcggacccagtgaaggcctggaaagaagctcagcaaaaggtcccagacgaa
gaagagaacgaagagagcgacacggagaaggagcctgagcgcagtgactccgcggccgat
tcggggccgaccttcaactacctcctggacatgcctctctggtacctgaccaaggagaag
aaggatgagctgtgcagactacggaatgaaaaagagcaagagctggaaacattgaagagg
aagggcccgtcggatttgtggaaggaagacctggctgcgtttattgaagaactggaggcc
gttgaagccaaggaaaaactagatgaacaagcaggactccccgggaaaggggggaaagca
aaaggaaaaaaagcacaagtggctgaagtcttgccttctccacggggacaaagagtcatt
ccccgagtgacctcagagatgaaagcagaggcagaaaagaaaatcagaaagaaaatcaag
agtgaaaatactgaaggaagccctaaggaagatggtgtggaagcagaagacttaaaacaa
agactagagaagaaacagaaacgagagccagggaccaaggcaaagaaacaaaccacactg
ccatttaaaccagtgaaaaaagcaaagaagagaaacccctggtctgactcggaatccgac
atgagcagtaacgaaagtaactttgatgttcctccacgagaagtcgagccacggagagca
gcagcgaaaacgaaattcactatggatttggattcagatgatgatttctcagattttaat
gaaaaaactcaagatgatgatgattttgtctcatcacctgctgatctacccaagaccaaa
acgtccccaaaacacacggacaaggaactgaagccacagcaaggtgccatgtcagtggcc
cctccagacagtgatacggagggcagtgccccgcttgctgctggggcccctgatgagact
gaagctgtgaagccggtacctaaaacaaacgtggcaatgaagaagacaacaacaaaaact
ctgtcttccacctccatcacgggtcccaagaaaagggggccgccaaaaggaaccaaaaag
aatccagcccccaaagctgacgtcccgcagaagcccgaggcccccaaagcgacgaagaat
ccgcgcaagagaaagccgtccatgtccgacgagtctgactccaacttcgaggaagttgtc
tccaaagcagtcgcaagcaagaaatctaaaggggacagcgataacttccatctggacctg
gactccgccgtggctcctcgggcaaaatccagccgggcaaagaagcccatcaagtacctg
gaagagtcagacgaagaggatctgttttaa
DBGET
integrated database retrieval system
