KEGG   Ochotona curzoniae (black-lipped pika): 121170470
Entry
121170470         CDS       T11174                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
ocz  Ochotona curzoniae (black-lipped pika)
Pathway
ocz00061  Fatty acid biosynthesis
ocz00620  Pyruvate metabolism
ocz00640  Propanoate metabolism
ocz01100  Metabolic pathways
ocz01212  Fatty acid metabolism
ocz04152  AMPK signaling pathway
ocz04910  Insulin signaling pathway
ocz04922  Glucagon signaling pathway
ocz04936  Alcoholic liver disease
Module
ocz_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:ocz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    121170470 (ACACA)
   00640 Propanoate metabolism
    121170470 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    121170470 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    121170470 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    121170470 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    121170470 (ACACA)
   04922 Glucagon signaling pathway
    121170470 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    121170470 (ACACA)
Enzymes [BR:ocz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     121170470 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     121170470 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     121170470 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 121170470
NCBI-ProteinID: XP_040857650
LinkDB
Position
Unknown
AA seq 2346 aa
MEETSPMAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGVSSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEDVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDKTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQV
YLPPPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFYVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVQSSVPLLSSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPAE
RKELESKLKEREEFLTPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq 7041 nt   +upstreamnt  +downstreamnt
atggaggaaacatctcccatggccaaacctctggagctcaaccagcactcccgatttata
attgggtctgtgtcagaagataactctgaggatgagatcagcaacctggtgaagctggac
ctgctggaggagaaggagggctctctgtccccggcttccgtcagctcagatacgctctct
gacctgggggtcagcagcctgcaggatggcttggccttgcacatgagatccagcatgtct
ggcttgcatctagtgaaacaaggtcgagaccgaaagaagatagactcacagcgggatttc
actgtggcttctccagcagaatttgttactcgtttcgggggaaataaagtgattgagaaa
gttcttattgctaacaatggcattgcagcggtgaaatgcatgcgctccatccgccggtgg
tcttacgaaatgtttcgaaatgagcgtgccatccggtttgttgtcatggtcactcctgaa
gacctgaaagccaatgcagagtacattaagatggcagatcactatgtcccagtgcccgga
ggcccaaacaacaacaactatgcaaatgtggaattgattctggatatcgctaagaggatc
ccagtccaagcagtgtgggccggctggggtcatgcctctgagaatcccaagctgccagaa
cttctcctgaaaaacggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcagactgctggtatcccaacacttccatgg
agtggcagtggtcttcgtgtggactggcaagaaaatgatttttcaaagcgtatcttaaat
gttccccaggaactgtacgaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gctgaggatgttggatacccagtcatgatcaaggcgtctgaaggaggaggagggaaggga
atcaggaaagtcaacaatgcagatgactttccaaacctcttcagacaggttcaagctgaa
gtccctggatctcctatctttgtgatgagacttgccaagcagtctcgtcatctggaggta
cagatcctagcggatcagtacggaaatgccatctctctgtttggtcgtgactgctccgtg
cagcgaaggcatcagaagattattgaagaggcacctgctgcaatagctactccagcagta
tttgaacatatggaacagtgtgcggtgaaacttgccaagatggttggttatgtgagtgcc
gggactgtggaatacctttacagccaggatggcagcttctactttctggagctgaaccct
cggcttcaggtggaacacccttgtacagagatggtagctgatgtcaatcttccagcagca
cagctccagattgccatggggattcctttatacaggatcaaggatatccgtatgatgtat
ggagtatctccctggggcgatgctcccattgattttgaaaattctgctcacgtcccttgc
ccaaggggccatgttattgctgcccggatcactagtgaaaatcccgatgagggttttaag
cccagctcaggaactgttcaggaactgaatttccggagcaataagaacgtctggggttac
ttcagtgttgctgctgcagggggacttcacgagtttgccgattctcagtttggccactgc
ttttcctggggagaaaatcgtgaggaagcgatttcaaacatggtggtggctttgaaggag
ctatctattcgtggcgactttcgaactacagttgaatacctgatcaaattgttagagaca
gaaagctttcagttgaataggatcgacactggctggctggacagattgatagcagaaaaa
gtacaggcagaacgccctgataccatgttgggagttgtatgtggggcccttcatgtggcc
gacgtgaacctgcggaatagcatctccaattttcttcactccttggaaagaggtcaagtg
cttcctgcccatacgcttctgaacacagtagatgttgaactgatttatgagggagtcaag
tatgtgcttaaggtgactcgacagtctcccaactcctacgtggtgatcatgaatggctca
tgtgtggaagtcgatgtgcaccggctcagtgacggcggactgctcttgtcctacgacggc
agcagttacacgacatacatgaaggaggaggtggatagataccgcatcacgattggcaat
aaaacctgcgtgtttgagaaggaaaatgacccatcagtaatgcgctcaccttcggctggg
aagttaatccagtacattgtggaggatggcggccatgtgtttgccgggcagtgctatgct
gagattgaggtgatgaagatggtgatgaccctaacagctgcagaatctggctgtatccat
tacgtcaagcgacctggagcagctcttgaccctggctgtgtaatcgccaaaatgcagttg
gacaatccgagcaaggttcagcaggcggagcttcacacgggcagcctgccccggatccag
agcaccgcactgagaggcgagaagctccaccgggtattccactatgtcctggataatctg
gtcaacgtaatgaatggttattgcctcccagaccctttcttcagcagcaaggtaaaggac
tgggtggaacggttgatgaagaccctcagagatccctccttgcccctcctagaattgcaa
gatatcatgaccagtgtctccggccgtattcctctcaatgtggaaaaatctatcaagaag
gaaatggctcaatatgctagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacattttagatagtcatgcagccacactgaaccggaaatcggagcgggaagtc
ttcttcatgaacacacagagcatcgtccagctggtacagaggtaccgaagtggcatccgg
ggccacatgaaggctgtggtgatggatctgctccggcagtacctgcgagtggaaacacag
ttccagaatggtcactatgacaaatgtgtatttgcccttcgggaggagaacaaaagtgat
atgaacaccgtactgaattacatcttctctcatgctcaagtcaccaagaagaatcttctg
gtcaccatgcttattgatcagttgtgtggccgggatcctacactcactgatgagctgcta
aatatcctcactgagctaactcaactcagtaagaccaccaatgccaaggtggcacttcga
gcccgccaggttcttattgcctcccatttgccatcctatgagcttcgccataaccaagta
gagtctatcttcttatcagctattgacatgtatggacaccagttttgcattgagaatctg
cagaaactcatcctgtctgaaacatctattttcgatgtcctgccaaacttcttctatcac
agcaaccaggtggtgaggatggcagccctggaggtgtatgttcgaagggcttatattgcc
tatgaacttaacagtgtacaacaccgccagcttaaggacaagacctgtgtggtggaattc
cagttcatgctgcccacgtctcatccgaatagagggaacatccccacgctcaacagaatg
tccttctcctccaacctcaaccactatggcatgactcatgtagctagtgtcagtgacgtg
ctgctggacaactcgttcactccaccatgtcagcggatgggcggaatggtctctttccgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgactcccca
cctcagagccccacgttcccagaggcaggccacacgtctctgtatgatgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaagactgactgcgacatcgaa
gatgacaggctggctgccatgttcagagagttcacccagcagaataaagcaaccctggtt
gagcatggaatccgacgtcttactttcctggttgcgcaaaaggacttcagaaaacaagtt
aactgtgaggtggatcagagatttcatagagaatttccaaaatttttcacattccgagca
agggataagtttgaggaagatcggatttatcgtcacttggagcctgctctggctttccag
ttagagctaaaccggatgagaaattttgacctcactgccattccttgtgccaatcacaag
atgcacctgtaccttggggcagccaaggtggaagtaggcacagaagtgacagactacagg
ttctttgttcgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcttttgaa
tatttacaaaatgaaggggaacgactacttctggaagccatggatgagctggaagttgct
tttaacaacacaaacgtccgcacagactgtaatcacatcttcctcaacttcgtgcccaca
gtcatcatggatccctcaaagattgaggaatctgtgaggagcatggtaatgcgctatgga
agtcggctgtggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccgactggaaaggcaattcccattcgcctcttcctgacaaacgagtctggctattacttg
gacatcagcctctacaaggaagtgactgactccaggacagcacagatcatgtttcaggca
tatggagacaaacaggggccgctgcacgggatgttaatcaatactccgtatgtgaccaaa
gacctactgcaatcaaagaggttccaggcacaatccctagggacaacgtacatctatgat
atcccagagatgtttcggcagtccttgatcaaactctgggaatctatgtccacgcaagta
taccttccaccacctcctctgccttctgacatgctgacgtataccgagctggtgttggac
gatcaaggtcaactggtgcacatgaacaggcttccaggaggaaatgagattggcatggtg
gcttggaagatgacccttaaaagtcctgagtatccagaaggccgagatatcatcgtaatt
ggcaatgacatcacataccgcattgggtcctttgggccccaggaggatctgctgtttctg
agagcttctgagctcgccagggcagaggggatcccccgcatctatgtagccgccaatagc
ggggcaagaattggactggcagaagaaattcgtcatatgttctatgtggcctgggtagac
cctgaggatccttacaagggatacaagtatttatatctgacccctcaagattataagagg
gtcagtgctctcaactctgtccattgtgaacatgtggaagacgaaggagaatccaggtac
aagataacagatattatcggaaaagaagaggggcttggagcagagaaccttcgaggttct
ggcatgattgctggagaatcctcgttagcctatgatgagatcatcaccatcagcctggtg
acatgtcgggccattgggattggggcttaccttgtccgactgggacagagaactatccag
gttgagaattctcacctgattctgacaggagccggggccctcaacaaagtccttggacgg
gaagtgtacacctccaacaaccagctcgggggcatccagatcatgcacaacaacggggtc
acccacagcacggtgtgtgatgactttgaaggggtgttcactgtcctgcactggctgtcc
tacatgccaaagagtgtacagagttctgttccgctcctgagctccaaggatcccatagac
agaatcatcgagtttgtgcccacaaaggctccatatgatcctcgatggatgctcgcaggc
cgtcctcacccaacccagaaaggtcagtggttgagtggattttttgactacggatccttc
tcagagattatgcagccctgggcacagactgtggtggttgggagagccaggctaggagga
atacccgtgggagtagttgccgtagaaacgcgaacagtagagctaagtatccctgcggat
cctgcgaacctggattctgaagccaagataatccagcaggctggccaagtttggttccca
gactctgcgtttaagacctaccaggccatcaaagacttcaaccgcgaagggttacctctg
atggtctttgccaactggcgaggcttctctggtggcatgaaagatatgtacgatcaggtg
ctgaagtttggtgcctacatcgtggacagcttgcgggagtgctcccagcccgtgatggtg
tacatccctccccaggccgagctgcggggtggctcctgggtggtgatcgaccccaccatc
aaccctcggcacatggagatgtacgccgaccgagagagcaggggatccgttctggagcca
gaagggacagtagaaatcaaattccgcaaaaaggatctggtgaaaaccatgcgtcgggtg
gacccggtctacatccgcttggctgagcgattgggcaccccggagctaagccctgccgag
cggaaggagctagagagcaagctgaaggagcgggaggagttcctgactcccatttaccat
caggtggctgtgcagtttgctgacctgcacgacaccccgggccggatgcaggagaaggga
gtcattaacgacatcctggactggaagacatcccgcaccttcttctactggcggctgagg
cgtctcctgctggaggacctggtcaagaagaaaatccacaacgccaaccccgagctgacg
gacggccagatccaggccatgctgcggcgctggtttgtggaagtggaaggaacagtgaag
gcctacgtttgggacaacaacaaggacctggtagagtggctggagaagcagctgacagag
gaagatggggtacgctcggtaatagaggaaaacatcaagtacatcagcagagactacgtc
ctcaagcagatccgcagcttggtgcaggccaaccccgaagtcgccatggattccatcgtg
cacatgacccagcacatctcccccacgcagcgggccgaagtcgtacggatcctctccacc
atggactccccctccacgtag

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