KEGG   Ochotona curzoniae (black-lipped pika): 121172419
Entry
121172419         CDS       T11174                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
ocz  Ochotona curzoniae (black-lipped pika)
Pathway
ocz04064  NF-kappa B signaling pathway
ocz04072  Phospholipase D signaling pathway
ocz04151  PI3K-Akt signaling pathway
ocz04380  Osteoclast differentiation
ocz04611  Platelet activation
ocz04613  Neutrophil extracellular trap formation
ocz04625  C-type lectin receptor signaling pathway
ocz04650  Natural killer cell mediated cytotoxicity
ocz04662  B cell receptor signaling pathway
ocz04664  Fc epsilon RI signaling pathway
ocz04666  Fc gamma R-mediated phagocytosis
ocz05152  Tuberculosis
ocz05167  Kaposi sarcoma-associated herpesvirus infection
ocz05168  Herpes simplex virus 1 infection
ocz05169  Epstein-Barr virus infection
ocz05171  Coronavirus disease - COVID-19
ocz05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ocz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    121172419 (SYK)
   04072 Phospholipase D signaling pathway
    121172419 (SYK)
   04151 PI3K-Akt signaling pathway
    121172419 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121172419 (SYK)
   04613 Neutrophil extracellular trap formation
    121172419 (SYK)
   04625 C-type lectin receptor signaling pathway
    121172419 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    121172419 (SYK)
   04662 B cell receptor signaling pathway
    121172419 (SYK)
   04664 Fc epsilon RI signaling pathway
    121172419 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    121172419 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121172419 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    121172419 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    121172419 (SYK)
   05168 Herpes simplex virus 1 infection
    121172419 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121172419 (SYK)
   05169 Epstein-Barr virus infection
    121172419 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    121172419 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocz01001]
    121172419 (SYK)
Enzymes [BR:ocz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     121172419 (SYK)
Protein kinases [BR:ocz01001]
 Non-receptor tyrosine kinases
  SYK family
   121172419 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7063 ABC1 SH2_1 RIO1
Other DBs
NCBI-GeneID: 121172419
NCBI-ProteinID: XP_040860229
LinkDB
Position
Unknown
AA seq 635 aa
MASNTSDNANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIERELNGTYAITGGRTHSSPADLCHYHSQESDGLVCLLKTPFNRPPGVEPKTGPFE
DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQI
VLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGSQQGNLDFDPRPQLPSSHPATWLAGGIISRIRSYTFPK
SGHKKAPPSQGNRPENSVSFNPYEPERGPWAAERGPQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPRE
MYELMNLCWTYDVEKRPGFVAVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggccagcaacacatctgacaacgccaatcacctgcccttcttcttcggaaacatcacc
cgggaggaggctgaggactacctggtccagggaggcatgagtgatgggctctacctgctg
cgccagagtcgcaattacctgggtggctttgccctgtcagtggcccacgggaggaaggca
caccattacaccatcgagagggagctcaatgggacctacgccatcacgggtggcagaacg
cacagcagccctgccgatctctgccactaccactcccaggagtcagatggcctggtctgc
ctccttaagacacccttcaaccggcctcccggggtggagcccaagacaggacccttcgag
gacttgaaggaaaacctcattagggaatacgtgaagcagacgtggaacctgcagggccag
gctctggagcaagccatcatcagtcagaagccgcaactggagaagctgatcgccaccacc
gcacatgaaaagatgccctggttccacgggaaaatctctcgagatgaatctgagcaaatc
gtcctgattggatccaagacaaatgggaaatttctgatcagggccagagacaacaatggg
tcctatgccctgtgcctgctgcacgaaggcaaggtgctgcactaccgcatcgacaaagac
aagactgggaagctctccatcccagaggggaagaagttcgacacgctttggcagcttgtg
gagcattattcctacaaacccgatggtttgttaagggtccttacggttccatgtcagaag
atcggttcacagcaaggaaaccttgattttgaccctcgtccacaacttccaagctcccat
cctgcgacgtggttggcaggtggaataatctccagaatcagatcctacaccttcccaaaa
tctggccacaaaaaggcacccccgtcccaaggaaaccggcctgagaacagcgtctcattc
aatccttacgagccagaacgagggccctgggcagccgaaagagggccccagagggaagcc
atgcccatggacacggaggtgtatgagagcccctacgccgaccctgaagagatcaggccc
aaagaggtctacctggaccggaagctgctgaccctggaagacaaagagctgggctctggt
aacttcgggaccgtgaagaagggctactaccagatgaagaaagtggtgaagacagtggct
gtgaaaatcctgaagaatgaggccaacgaccccgccctgaaagacgagctgttggcggaa
gccaacgtcatgcagcagctggacaacccctacatcgtgcgtatgatcgggatctgcgag
gctgagtcctggatgctggtgatggagatggcggaacttggcccgctcaataagtatctg
cagcagaacaggcacgtcaaggacaagaacatcatagagttggttcatcaggtctccatg
gggatgaagtacttggaggagtgcaattttgtgcacagagatctggctgcaagaaacgtg
ctgctggtcacccaacattacgccaagatcagcgactttgggctttccaaggcgctcagg
gccgatgaaaactactacaaggcacagacgcacggcaagtggcccgtgaaatggtacgcc
cccgagtgcatcaactactacaaattctccagcaagagtgacgtttggagcttcggtgtg
ctgatgtgggaagcgttttcctatgggcagaagccatatcgggggatgaaagggagtgaa
gtgactgccatgttggaaaaaggcgagcggatgggatgccctcccgggtgcccaagggag
atgtacgaactgatgaacttgtgctggacatacgacgtggagaaaaggcccgggtttgta
gcagtggaactgcggctgcgtaattactactacgacgtggtgaactaa

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