KEGG   Ochotona curzoniae (black-lipped pika): 121172421
Entry
121172421         CDS       T11174                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1 isoform X1
  KO
K02599  Notch 1
Organism
ocz  Ochotona curzoniae (black-lipped pika)
Pathway
ocz01522  Endocrine resistance
ocz04330  Notch signaling pathway
ocz04658  Th1 and Th2 cell differentiation
ocz04919  Thyroid hormone signaling pathway
ocz05020  Prion disease
ocz05165  Human papillomavirus infection
ocz05200  Pathways in cancer
ocz05206  MicroRNAs in cancer
ocz05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:ocz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    121172421 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    121172421 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    121172421 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121172421 (NOTCH1)
   05206 MicroRNAs in cancer
    121172421 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    121172421 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    121172421 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    121172421 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    121172421 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_4 Ank_3 Ank_5 EGF_3 EGF_Teneurin Gurken_M EGF_DL_JAG
Other DBs
NCBI-GeneID: 121172421
NCBI-ProteinID: XP_040860236
LinkDB
Position
Unknown
AA seq 2541 aa
MRPLLAPLICLALLPALAARGLRCSQPAESCLNDGRCEVANGTEACVCSGAFVGPRCQDP
SPCLSSPCRNSGTCHVVERMGAVDYTCTCPLGFSGPLCLTPLDHACVPNPCRNGGTCDLL
TLSEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCLSGFHGPTCRQDVN
ECTQTPGLCRHGGTCHNLVGSFRCACRPTHTGRRCELPFVPCSPSPCQNGGTCHPTGDTT
HECACLPGFTGQSCEQNVDDCPAHSCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ
LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCE
CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGA
NPCEHAGRCLNTLGSFECQCLQGYTGPRCEMDVNECVSNPCQNDATCLDQIGEFQCICMP
GYEGVYCEVNTDECASSPCLHNGRCLDKTNEFLCECPTGFSGHLCQYDVDECASTPCKNG
AKCLDGPNTYTCVCAEGYTGTHCEVDIDECVPDPCHYGTCKDGVATFTCLCQPGYTGHHC
ETNINECYSQPCRHGGTCQDRDNAYFCFCLKGTTGPNCEINLDDCASNPCDSGTCLDKID
GYECACEPGYTGSLCNINIDECASSPCRNGGTCEDGINAFTCRCPEGYHDPTCLSEVNEC
NSSPCVHGVCKDSLNGYTCDCAPGWSGTNCDVNNNECESNPCVNGGTCRDMTGGYVCTCR
EGFSGSNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEGVLAPCAPGPCRN
AGKCQESEDYESFSCICPQGWQGQTCEVDINECVKNPCLHSASCQNTRGGYHCLCRPGYT
GRNCETNVDDCRPNPCHNGGSCTDGINMAFCDCLPGFQGAFCEEDINECASNPCRNGANC
TDCVDSYTCTCPAGFNGIHCEHNMPDCTESSCFNGGTCVDGIDSFTCLCPAGLTGSYCQY
NINECDSRPCLHGGTCQDSYGTYKCTCPQGYTGPNCQNLVRWCDSLPCKNGGHCWQSSTR
YHCECLSGWTGLHCDVPSVSCEVAARKRGMDVAQLCQHGGLCVDADNTHYCRCPAGYTGS
YCEDEVDECSPSPCQNGATCTDYLGGYSCKCVPGYHGANCSEEVNECLSLPCQNGGTCID
LTNSYKCSCPRGTQGVHCEINVDDCSPPVDPATRNPRCFNNGTCVDQVGGYSCSCPPGFV
GERCEGDVNECLSNPCDPHGTQDCVQRVNGFHCECRAGHTGRRCESVINGCRGRPCKNGG
TCAVAANTARGFICKCPAGFEGATCENDARSCGSLRCLHGGTCVSGPRSPTCLCLASFTG
PQCQFPASSPCVGNNPCYNQGSCEPTAESPFFRCLCPPKFNGLLCHILDYSFGGGAGRDI
PPPVIEEACELPECREDAGNKVCSLPCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF
SDGRCDAQCNTPGCLFDGFDCQGAEGHCNPLYEQYCQDHFSDGHCDQGCNSAECEWDGLD
CAEHVPERLAAGTLVVVVLLPPEQLRNSSFHFLRELSRLLHTNVVFKRDAQGQRMIFPYY
GREEELRKHLVKRAVGAEGWAAPGSLLGRVLPGSGAERRRRELDPMDVRGSIVYLEIDNR
QCVQSSVQCFQSATDVAAFLGALASLGSLSIPYKIEAVQSKTVEPPPPSQPHLMYVAAAA
FLLLFFLGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKRREPLGEDSVGLKPLKNASDGA
LMDDNQNEWGDEDLETKKFRFEEPVVVPELDDQTDHRQWTQQHLDAADLRVSAMAPTPPQ
GEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEDEEDAPAVISDFIYQGASLHNQT
DRTGETALHLAARYSRSDAAKRLLEASADANIQDNTGRTPLHAAVSADAQGVFQILIRNR
ATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAA
IVLLKNGANKDMQNHKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER
MHHDIVRLLDEYNLMRSPPLHGPALGGTPTLSPPLCSPGGYLGNLKPAVPGKKARKPSSK
GLACSGKDPKDLKARRKKSQDGKGCLLDTSSMLSPVDSLESPHGYLSDVASPPLLPSPFR
QSPSVPLSHLPGMPDTHLGLSHLSVATKPEMAALGGGGGRLPFEPGPPRLSHLPVASGSG
TVLGASGVGGAVNFAVGGAAGLNGQCEWLSRLQNGMVPNQYSPLHGSTAAGGLSTQAPTL
QHGMMGPLHSGVSANTLSQMVSYQALPSARLAAQPPLVPTQQVAPQNLQLQPPQGLQTAP
QAHLGVGSAASSHLGRSFLGSEQSQADAQPLGPSSLPVHTILSPEGQALPTSLPSSLAPP
MTTAQFLTPPSQHSCSSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNISDWSE
GVSSPPTSMQPPLAHIPDAFK
NT seq 7626 nt   +upstreamnt  +downstreamnt
atgcggccgctgctggcacccctgatctgcctggcgctgctgcccgcgctggccgcgaga
ggcctgagatgctcacagccagccgagagctgcttgaatgacggcaggtgtgaagtggcc
aacggcaccgaggcctgtgtctgcagcggggccttcgtgggccctcgatgccaggacccc
agtccatgcctcagcagcccctgccggaactcgggcacgtgccacgtggtggagcgcatg
ggcgccgtggattatacctgcacctgccccctgggcttctcgggacccctgtgcctgacg
cccctggaccacgcctgtgtccccaacccctgccggaacgggggtacctgcgacctcctc
acgctgtcagagtacaagtgccgctgtcccccaggctggtcagggaagtcatgccagcag
gcagacccgtgtgcctccaacccttgtgccaacggcggccagtgcttgcccttcgagtcg
tcctacatctgccgctgcctgtccggcttccacggccccacgtgccggcaggatgtaaat
gaatgtactcagacccccgggctctgccgccacgggggcacctgccacaacctggttggc
tccttccgctgtgcctgccgccccacccacaccggccgccgctgcgagctgccctttgtg
ccctgcagcccctcgccctgccagaacggaggcacctgtcaccccacgggcgacaccacg
cacgaatgtgcctgtctcccaggcttcaccggccagagctgcgagcagaatgtagatgac
tgcccggcacacagctgcaagaacgggggcgcctgtgtggacggtgtgaacacctacaac
tgccgctgcccgcccgaatggacaggccagtactgcacggaggacgtggacgagtgccag
ctcatgcccaacgcctgtcagaacggcggcacttgccataacacccacggcggctacaac
tgcgtgtgcgtcaacggctggacgggcgaggactgcagcgagaacattgacgactgtgcc
agtgctgcctgctttcaaggcgccacctgccacgaccgcgtggcctccttctactgcgag
tgcccccacggccgcaccggtctgctttgccacctgaatgatgcctgcatcagtaaccct
tgcaacgagggttccaactgtgacacgaaccctgtcaacggcaaagccatctgcacctgc
ccctcggggtacacagggccagcctgcagccaggacgtggacgagtgtgccctgggcgcc
aacccctgtgagcacgcgggcaggtgcctcaataccctgggctcgttcgaatgccagtgc
ctgcagggctacacgggcccccgctgtgagatggatgtgaatgagtgtgtgtccaacccc
tgtcagaatgatgccacctgcctggaccagatcggggagttccagtgtatctgcatgcca
ggctacgagggcgtgtactgcgaagtcaacacagacgagtgtgccagcagcccctgctta
cacaacggccgctgcctggacaagaccaacgagtttctgtgcgaatgtcctacaggtttc
agcgggcacctatgccagtatgatgtggacgagtgtgccagcacgccctgcaagaacggt
gccaagtgcctggacggacccaacacctacacctgcgtgtgtgctgaaggctacacgggg
acccactgcgaggtggacatcgacgagtgtgtccctgacccctgtcactacggcacctgc
aaggacggtgtggccaccttcacttgcctgtgccagcccggctacactggccaccactgt
gagaccaacatcaatgagtgctacagccagccctgccgccacggaggcacctgccaggac
cgagacaatgcttacttctgcttctgcctcaaggggaccacaggtcccaactgtgagatc
aacctagatgactgtgccagcaatccctgtgactcgggcacctgcctggacaagattgat
ggttacgagtgtgcctgtgagccgggctacacaggcagcctgtgcaacatcaacattgat
gagtgtgccagcagcccctgccgtaacggtggtacctgtgaggatggcatcaatgccttc
acctgccgttgccccgagggttaccacgaccccacctgcctgtccgaggtcaatgagtgc
aacagcagcccctgtgtccacggggtttgcaaggacagtctgaacgggtacacgtgtgac
tgtgcccccggctggagcgggaccaactgtgatgtcaacaacaacgagtgtgaatccaac
ccctgtgtcaacggcggcacctgcagggacatgaccggtggctacgtgtgcacctgccgg
gagggcttcagtggctccaactgccagaccaatatcaacgagtgtgcgtccaacccgtgc
ctgaaccagggcacgtgtatagatgacgtggctggctacaagtgcaactgcccgctgcct
tacacgggagccacctgtgagggggtcctggccccctgcgcccccggtccctgcaggaat
gctggcaagtgccaggagtcagaagactatgagagcttctcctgcatctgcccccaaggc
tggcaggggcagacctgtgaggtggacatcaatgagtgtgtgaagaacccgtgcctccac
agcgcctcctgtcagaacacgcgtggcggctaccactgcctctgccggcccgggtacaca
ggccgcaactgcgagaccaacgtggacgactgtcggcccaacccatgtcacaatggcggc
tcctgcacagacggcatcaacatggccttctgcgactgcctgccgggtttccagggcgcc
ttctgcgaggaggacatcaacgaatgcgccagcaacccctgccgcaacggcgccaactgc
accgactgcgtggacagctacacctgcacctgcccggccggcttcaacggcatccactgt
gagcacaacatgccggactgcaccgagagctcctgcttcaacggcggcacgtgtgtggat
ggcatcgactccttcacctgcctgtgcccggccggcctcacgggcagctactgccagtac
aacattaacgagtgtgactcacgaccctgcctgcacggcggcacctgccaggacagctat
ggcacctacaagtgcacctgtccccagggctacaccggccccaactgccagaacctcgtg
cgctggtgtgactcattgccctgcaagaacggaggccactgctggcagagcagcacccgc
taccactgcgagtgcctcagcggctggaccggcctccattgcgacgtgcccagcgtctcc
tgtgaggtggctgcccgcaagcgaggcatggacgttgcccagctgtgccagcacgggggc
ctgtgtgtggacgcagacaacacgcactattgtcgctgcccggccggctacacgggcagc
tactgtgaggacgaggtggacgagtgctcgcccagcccctgccagaacggggccacctgc
accgactacctgggcgggtactcctgcaagtgtgtgcctgggtaccatggggccaactgc
tccgaggaggtcaacgagtgcctttcgctgccgtgccagaacggtggcacctgcatcgac
ctcaccaacagttacaagtgctcctgcccccggggcacgcagggtgtgcactgcgagatc
aacgtggatgattgcagtccacccgtggaccccgccacgcggaaccccaggtgcttcaac
aacggcacctgtgtggaccaggtgggcgggtacagctgcagctgcccaccgggcttcgtg
ggcgagcggtgcgagggcgacgtgaatgagtgcctgtccaatccctgcgacccccatggc
actcaggactgcgtgcagcgcgtcaacggctttcattgcgagtgccgcgccggccacact
gggcgccgctgtgagtccgtcatcaatggctgcaggggccggccctgcaagaatgggggc
acctgcgccgtagcagccaacactgcccgcggcttcatctgcaagtgcccagcgggcttt
gagggcgccacgtgtgagaatgacgcgcgttcctgcggtagcctgcgctgcctgcatggt
ggcacctgcgtctcgggcccgcgcagccccacctgcctgtgcctggcctccttcaccggc
ccccagtgccagttcccggccagcagcccctgcgtgggcaacaacccctgctacaaccag
ggcagctgcgagcccaccgccgagagccccttcttccgctgcctgtgccctcccaagttc
aacgggctgctctgtcacatcctggactacagctttggtggcggggcgggccgcgacata
ccgccgccggtcatcgaggaggcgtgcgagctgcccgagtgccgggaggacgcgggcaac
aaggtgtgcagcctgccgtgcaacaaccatgcgtgcggctgggacggcggcgactgctcg
ctcaacttcaacgacccgtggaagaactgcacgcagtctctgcagtgctggaagtacttc
agcgatggccgctgcgatgcccagtgcaacacccctggctgtctcttcgacggctttgac
tgccagggcgcggagggccactgcaaccccctgtacgagcagtactgccaggaccacttc
agcgacggacactgcgaccagggctgcaacagtgccgagtgtgagtgggacgggctggac
tgcgcggagcacgtgcccgagcgcctggcggccggcacgctcgtggtggtggtcctcctg
ccgcccgagcagctccggaacagctccttccacttcctgcgggagctcagccgcctgctg
cacaccaacgtggtgttcaagcgcgacgcccagggccagcggatgatcttcccctactat
ggccgcgaggaggagctgcgcaagcacctggtcaagcgagccgtcggggccgagggctgg
gccgcgcccgggagcctgctgggccgcgtgctgcccgggagcggggccgagcgccggcgc
agggagctggaccccatggacgtgcgcgggtccatcgtgtacctggagattgacaaccga
cagtgcgtgcagtcgtccgtgcagtgcttccagagcgccaccgacgtggccgccttcctg
ggggcgctggcctcgctgggcagcctcagcatcccctacaagattgaggccgtgcagagt
aagacggtggagccgccgccaccctcgcagccgcacctcatgtacgtggccgccgccgcc
ttcctgctgcttttcttcctcggctgcggggtgctcctgtcacgcaagcgccggcggcag
catggccagctctggttccccgagggcttcaaggtgtcggaggccagcaagaagcggcgc
gagcccctgggcgaggactcggtgggcctcaagcccctgaagaatgcctcggacggggcc
ctcatggacgacaaccagaacgagtggggcgacgaggacctggagaccaagaagttccgg
ttcgaggagcccgtggttgtccccgagctggatgaccagacggaccaccggcagtggacg
cagcagcacctggacgctgccgacctgcgtgtgtcggccatggcccccacgccgccccag
ggcgaggtggacgccgactgcatggacgtgaacgtgcgtgggcctgatggcttcaccccg
ctcatgatcgcctcctgcagcggaggcggcctggagacgggcaacagtgaggacgaggaa
gacgcacctgccgtcatctcggacttcatctaccagggcgccagcctgcacaaccagact
gaccgcaccggtgagacggcgctgcacctggccgcccgctactcgcgctccgacgccgcc
aagcgcctgctggaggccagcgccgacgccaacatccaggacaacaccgggcgcaccccg
ctgcacgcggccgtgtctgcggacgctcagggcgtcttccagatcctgatccgtaaccga
gccacagacctggacgcacgcatgcatgacggcaccacgccgctgatcctggccgcccgc
ctggccgtggaaggcatgctggaggacctcatcaactcacacgccgacgtcaacgccgtg
gacgacctgggcaagtcggcgctacactgggcagctgctgtgaacaatgtggacgccgcc
atcgtcctgctcaagaacggcgccaacaaggacatgcagaaccacaaggaggagacgccc
ctgttcctggccgcccgcgagggcagctacgagacggccaaggtgctcctggaccacttc
gccaaccgggacatcacggaccacatggaccgcctgccgcgtgacatcgcccaggaacgc
atgcaccatgacatcgtgcggctgctggacgagtacaacctgatgcgaagccccccgctg
catggccctgccctgggcggcacgcccaccctgtctcccccgctctgctcgcctggcggc
tacctgggcaacctcaagccggccgtgccgggcaagaaggcccgtaaacccagcagcaaa
ggcttggcctgcagcggcaaagaccccaaggacctcaaggcacggcggaagaagtcgcag
gacggcaagggctgcctgctggacacctccagcatgctgtcgcccgtggactccctggag
tcaccccacggctacctgtccgacgtggcctcaccgcctctgctgccctcaccattccgg
cagtccccatccgtgcctctcagccacctgcccggcatgcctgacacccacctgggcctt
agccacctgagcgtggccaccaagccagagatggcggcgctgggtggcggcggtggccgg
ctgcccttcgagcccggccctccgcgcctgtcccacctgccggtggcctccggcagtggc
acggtgctgggtgccagcggcgtgggaggggccgtgaatttcgcggtgggtggggcggcc
ggcctgaacggccagtgcgagtggctctcccggctgcagaacggcatggtaccgaaccag
tacagccctctgcatggcagcacggccgccgggggcttgagcacgcaggcgccgaccctg
cagcacggcatgatgggcccgttgcacagcggtgtgtctgccaacaccctgtcccagatg
gtgagctaccaggccctgccctccgcgcggctggctgcccagcctcccctggtgccaaca
cagcaggttgcaccgcagaacttacagctgcagccgccacagggcctgcagacggcaccg
caggcgcacctcggcgtgggctcagcggcctccagccacctgggccggagcttcctgggc
agcgagcagagccaggcggacgctcagccactgggccccagcagcctgccggtgcatacc
attctgtccccggagggccaggcgctgcccacctcgctcccgtcctcgctggccccgccc
atgaccacggcacagttcctcacgccgccctcccagcacagttgctcctcgtcgcccgtg
gacaacacgcccagccaccagctgcaggtgcccgagcacccgttcctcacaccgtccccc
gagtcccctgaccagtggtccagctcctcgccgcactccaacatctccgactggtccgag
ggcgtgtccagcccgcccaccagcatgcagcccccgctcgcccacatccctgacgccttc
aagtga

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