Ochotona curzoniae (black-lipped pika): 121172489
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Entry
121172489 CDS
T11174
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00790
Folate biosynthesis
ocz01100
Metabolic pathways
ocz01240
Biosynthesis of cofactors
ocz01523
Antifolate resistance
ocz04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
121172489 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
121172489 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121172489 (FPGS)
Enzymes [BR:
ocz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
121172489 (FPGS)
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SSDB
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
121172489
NCBI-ProteinID:
XP_040860455
LinkDB
All DBs
Position
Unknown
AA seq
574 aa
AA seq
DB search
MSWARRHLHAALALAAVSARAATTEGAARRELSTRPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRGDPQAQLEAMELYLTRSGLQLEDLDRLNIIHVTGTKGKGSTCAFTEHILRN
YGLKTGFFSSPHLVQVRERIRINGQPISRELFTKHFWRLYHRLEETKDDNYNSMPAYFRF
LTLMAFHVFLQEQVDLAVMEVGIGGAYDCTNIVRKPVVCGVSSLGMDHTNLLGDTMEKIA
WQKGGIFKCGVPAFTSLQPEGPLAVLRDRAQQISCPLYLCPPLEVLEEGGPPLSLGLEGE
HQRANAALALQLAHCWLRRQEHQDTGELKSSQPGVLWQLPLAPVFQPTERMRHGLRDTEW
LGRTQVLRRGPLTWYLDGAHTTSSVQACVRWFLGALQQQERPSVGSEVRVLLFNSTGDRD
SAALLKLLQPCQFDYALFCPNLTEVSFTGDADQQNFMVTLDQVLHRCLEHQQHWSHLNDG
VRSPHSPGQAGSLLHPSSSTSLVFSCISHALQWISQGRDPVSQSPSPPRGLLPFSLASGK
TKVLREATAVHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagacacttgcacgccgccctggctctggcagcggtttctgctcgt
gctgcaacgacagaaggagccgcgcggcgggaactgagcacgcggccggctccgcaggag
cccggcatggagtatcaggatgccgtgcgcatgctcaataccctgcagaccaatgccagc
tacctggagcaggtaaaacgccagcggggcgacccccaggcccagctggaagccatggaa
ctctacctgacacggagtggcctacagttggaggacctggaccgcctgaacatcattcac
gtcacggggaccaaggggaagggctccacctgcgccttcactgaacacatccttcggaac
tatgggttgaagacaggattttttagctctcctcacctggtacaggtacgtgagcggatc
cgcatcaacgggcagcccatcagccgcgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggacgacaactacaactccatgcctgcctacttccgcttc
ctcacgctcatggccttccacgtcttcctccaagagcaggtggacttggcggtgatggaa
gtaggcattggtggggcctacgactgcaccaacatcgtcaggaagcccgtggtgtgcggt
gtctcctcccttggcatggaccacaccaatctcctcggggacacaatggagaagattgca
tggcagaaggggggcatctttaagtgtggtgtcccagctttcacatctctccagcctgag
gggcccctggcggtgctcagagaccgagcacagcagatctcgtgtcccctttacctgtgc
ccaccgctggaagtcctggaggagggtgggccaccgctgagcctgggcctggagggcgag
caccagcgggccaatgctgccctggccttgcagttggcgcactgctggctgcggaggcag
gagcaccaagacactggcgagctgaagtcctcccagcccggcgtcctgtggcagctgccc
ctggcgcccgtgttccagcctacagagcgcatgaggcacgggcttcgggacacggaatgg
ctgggccgcacgcaggtactgaggcgtgggccactcacctggtacctggatggtgcgcac
accaccagcagcgtgcaggcctgtgtgcgctggttccttggggcgctgcagcagcaggag
agaccgagcgtcggctcggaagtacgtgtcctgctcttcaactccactggggaccgggac
tcagcggccctgctgaagctgctgcagccctgccaatttgactatgctctcttttgcccc
aacctgacagaggtgtcattcacaggtgacgcagaccagcagaactttatggtgaccctg
gaccaggtgctgcaccgctgcctggagcaccagcagcactggagccacctgaatgacggt
gtccggagcccccacagcccagggcaggcaggatccctgctccacccttccagcagcacc
tccttggttttcagctgcatctcgcacgccttgcagtggatcagccaaggccgggatcca
gtctcccagtcccccagccccccgagaggtctcctccccttctccctggccagcggcaag
accaaggtactccgggaggctactgctgtccatgtgctggtcacaggcagcctgcacctt
gtgggcggcgtgctgaagctgctggacccctccctgtcccagtag
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