Oryx dammah (scimitar-horned oryx): 120853265 Help Entry 120853265         CDS       T07255                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda04020   Calcium signaling pathway oda04371   Apelin signaling pathway oda04713   Circadian entrainment oda04921   Oxytocin signaling pathway oda04970   Salivary secretion oda05010   Alzheimer disease oda05012   Parkinson disease oda05020   Prion disease oda05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:oda00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     120853265 (RYR3)    04020 Calcium signaling pathway     120853265 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     120853265 (RYR3)   09154 Digestive system    04970 Salivary secretion     120853265 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     120853265 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     120853265 (RYR3)    05012 Parkinson disease     120853265 (RYR3)    05020 Prion disease     120853265 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     120853265 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:oda04040]     120853265 (RYR3) Ion channels [BR:oda04040]  Voltage-gated cation channels   Ryanodine receptor    120853265 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Motif Other DBs NCBI-GeneID:  120853265 NCBI-ProteinID:  XP_040082946 LinkDB All DBs Position Unknown AA seq 4864 aa AA seqDB search MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYL TCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSLSNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTD QNDSQHRRIYYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTED QGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIAS GLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQ FVSGNSRTAAPVTLPIEEVLQTLHDLIAYFQPPEEGMQHEGKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSN NLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDV LCSLCLCDGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRIPRAVASINQHLLKSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVS FSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGIRDLLGT TQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKMRDDNKR QHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKLPKNYMMS NGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYSLLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSY AVRSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGVDDQAFVFEGSRGQRWHQGSGYFGR TWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIDNGFVPICSLGLSQIGR MNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVVRID GTMDTPPCLKVTHKTFGTQNSSATMIYCRLSVPVECHSSFSHSPCLDSDAFQKRKQMQEI LSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHE SVKRSNCYMVWGGDIVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPN TKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLW SRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYH TLRLYSALCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKE RKLMMKNEYIIPITSTIRKIRLYPDESKRHGLPGVGPRTCLKPGFRFSTPCFITTNEEHQ KQSPEIPLELLKTKALGMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDD DDVRQILLLIDPSVFGEHSGETEEGGEKEEVTQVEEKAVEAGEKASREAPIKGLLQTRLP ESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQENQKFRYNELMQALNMSAALTA RKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEED TSWTGKFCALVQRIKGPPKPEKEQPTEEEERCPTTLKELISQTMIRWAQEDQIQDAELVR MMFNLLRRQYDSIGELLQALRKTYTISQASVSDTISLLAALGQIRCLLSVRMGKEEELLM INGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKSQIAFPKMVASCCRFLCYF CRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLE KVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKL LIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVTEDDEDEEEIVHM GNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPS LNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDT VSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHCTSLIDSTLQTIYRLSKGRSLTKA QRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLP SGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDPDLFRMALPCLSAIAGALPPDYLDTR ISATLEKQVSVDADGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDKWACDKSQSGWKYG ISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGEALVQQREN EKLRSVSQASQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGG SHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGVKDMELDASSMEKRFAYKFL KKVLKYVDSAQEFIAHLEAIVSSGKNEKSPHDQEIKFFAKVLLPLVDQYFTNHRLYFLSS PLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSATMVSCLHILAQTLDTRTV MKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPIL TSIFEHVAQHQFGVDLLLGDVQLSCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAA IPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESG ARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSAGPWCTKVTSEHLSVILGNILKIIN NNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAIKTVQEEEQLRADSK GDTQEAELLILDEFAILCRDLYAFYPMLIRYVDNSRSNWLKSPDADSDQLFRMVAEIFIL WCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGQDQERKKTKRRGDFYSIQTSL IVAALKKMLPIGLNMCTPGDQELISLAKSRYSYRDTDEEVKEHLRNNLHLQEKSDDPAVK WQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRA VVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEEEEEEEV EKQPDPLHQIILHFSRNALTERSKLEDDPLYTSYASMMAKSCQSGEDEDEEEDKEKTFEE KEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQK MLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVL QNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYW YYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHV FANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNV EMILKFFDMFLKLKDLTSSDAFKEYDPDGKGIISKKEFQKAMEGQKQYTQSETDFLLSCA EADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFE PYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFV NFCEDTIFEMQLASQISESDSADRPEEEEEEDGDSSYVLEVEGEEEEEKSFECASAFAMA CASVKRNVANFLKRATLKNLRKQYRKVKKMTFKELVKLFFSFFWTLFVGLFHLLFTIVGG IIQVLWSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDAMEAERAEVPEPGLTTELV HFVKGEKGDADIMSDLFGLHPKKEGGLKHGPEVGLGDLSEIIGKDEPPTLESTVRKKRKA QAAEMKASHEAEGKIESEKADMEDGEKEHTAKEEQAEALWADVTKRKKRRCGQKVEKPEA FMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVA NLWNSFNDEEEEEAVVFFVLQESTGYMAPALRALAIIHTVISLVCVVGYYCLKVPLVVFK REKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLY GAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHVWKLGVVFTDNSFLYLA WYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTV VAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYR IVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPH GFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYE DQLG NT seq 14595 nt NT seq  +upstreamnt  +downstreamnt atggccgaagggggagaaggaggcgaagacgagatccagttcctgcggactgaagatgaa gtggtcctccagtgcattgccaacgttcacaaggagcagaggaagttctgcctggcagcc gagggacttgggaatcgcctgtgctttttggaacccacttcagaagccaagtatgttcct ccagatctctgcgtctgcaactttgtgctggaacagtccctctctgtcagagccctgcag gagatgcttgccaacacaggtgaaaatggcggcgaaggggcagcacaagggggtggccac aggaccctgctgtatggccatgcaattctcctgcggcactccttcagtggcatgtaccta acatgtttgaccacatcaagatcccagacggataaacttgcctttgatgtaggtctacgg gaacacgccacaggagaagcctgttggtggaccattcatcccgcttccaagcagaggtct gagggagaaaaggttcgaattggtgatgacctcatcctcgtcagtgtgtcctctgaaaga taccttcatctctcactatcaaatggtaacatacaagtggatgcctcctttatgcagaca ctctggaatgtacatcctacgtgctcaggaagtagcatcgaagaaggatacctacttggt ggacatgtagtacgtcttttccatggtcatgatgagtgtttgacgataccatctacagac cagaatgattcccagcacaggaggatatactatgaagccgggggagctggcacgagagcc agatcgctatggagagtggaaccccttcggataagctggagtggcagtaacatcagatgg ggacaggctttccgcctccggcacctcaccacaggccactacctggccttgacagaagac cagggccttatcctgcaagaccggggaaagtcggacaccaagtccacagccttctctttt cgggcatccaaggaaatcaaggagaaattggattccagtcacaagcgagatatagaaggc atgggagtcccagaaatcaagtatggagactctgtctgctttgtccagcatatagccagt ggtctgtgggtgacctacaaagcacaagatgccaagacatcccgcctgggacctctgaaa agaaaggtcatactccatcaggaaggccacatggatgatgggttaacactgcagagatgc cagcgtgaggagtcccaggctgctcggatcatccggaacacgaccgccttattcagccag tttgtaagtggaaacagtcgcacagctgccccagtcaccctgccaatagaagaggtcctg cagaccttacatgacctgattgcctacttccagcccccggaggaggggatgcagcatgaa ggcaagcagagcaagctccgctcactcaaaaacagacagaatcttttcaaggaagaggga atgttagcccttgtgttaaactgcattgatcgcttaaatatctacaatagcatagcacac ttcgcagggatcgccagggaggagagtgggatggcctggaaagaaattctgaacctcctc tacaaattgctcgctgctcttattcgtggcaacagaaacaactgtgctcaattctccaat aaccttgattggctgatcagcaaattggacagactagaatcttcctcaggtatcttggaa gttttgcactgcatcctcattgaaagcccagaagccttaaacctgatagcagagggccac atcaagtccatcatctccctgttggataagcacggacggaatcacaaggttctggatgtg ctgtgttccctctgtctctgcgatggggtcgcagtgagagccaaccagaatctcatctgt gacaacttgctgccccggagaaacctgctcctgcagacacggctgattaatgacgtaaca agtattcggccaaacatcttcctgggagttgctgaaggctcagcacagtataagaagtgg tacttcgagcttatcatcgaccaggtggaccccttcctcacagcagagcccacgcatctg cgggtgggctgggcctcttcctctggctacgctccttaccccggaggtggagaaggatgg ggaggcaatggtgttggtgatgacctatactcctatggctttgatggactgcacctctgg tcaggtcgcatacccagagccgtggcctccatcaaccagcacctcctgaagtcagacgac gtggtaagctgttgcctggacctgggggcacccagcatctctttccgcatcaacgggcag cctgtgcaggggatgtttgagaacttcaacacggatgggctcttcttccctgtggtgagc ttttcagcaggtgtcaaagtacgtttcctgctgggtggacgtcatggagaatttaagttc ctgcctccctctggctatgccccttgctatgaagccttgcttccgaaggaaaagatgaga ttggagcctgtcaaagagtataaacgtgatgctgaaggaattcgagatctgttgggtacc acccagttcctttcccaagcctctttcatcccatgccccatagataccagtcaggtggtt ttaccacctcatctagagaaaatcagagacaggctggctgaaaacatccacgagctttgg ggaatgaataaaatagagcttggctggacttttggcaagatgcgggatgacaataagaga cagcacccctgccttgtcgagttttcaaagctgcccgaaactgagaagaattataaccta caaatgtcaactgaaaccctaaaaactctcctggccctggggtgccacattgctcatgtt aacccagctgctgaggacgatctcaagaaggtcaaattgcccaaaaactacatgatgtcc aatggctataagccagcccctttggatttgtctgatgtgaagctgttacctcctcaagaa attttagtggataagcttgcagaaaatgcacacaatgtctgggcaaaagacagaataaaa caaggatggacctatggcattcaacaggatttaaagaacaaaagaaatccacgtttggtg ccatattcattgctggatgagcgtaccaagaagtcaaacagggacagccttcgtgaagct gtccggacgtttgttggttatggctataacattgagccatcagaccaagagctagctgac ccagctgtggagaaagtcagcatagacaagatccgctttttccgggtagagcgctcttat gccgtgagatcggggaagtggtatttcgagtttgaggtggtgaccggaggcgacatgcgt gttggctgggcccggccaggctgccgacctgacattgagctaggggtggatgaccaagcc ttcgtgtttgaaggcagcaggggccagcgttggcatcaagggagtgggtatttcggacgg acctggcagccaggagatgtggttggatgtatgattaacctggatgatgcttcaatgatc ttcacgctgaatggggagctgctgatcaccaacaaaggctctgaacttgccttcgctgac tacgagattgacaatggctttgtgcccatctgctctctggggctgtctcagatcggccgc atgaatctcgggatggacgctagcaccttcaagttttataccatgtgtggtctccaagag ggttttgagccttttgctgtcaacatgaatcgcgacgtggccatgtggttcagcaaacgc ctcccaacatttgtcaacgtgcccaaggatcatccgcagatagaggtcgtgaggatcgac ggcaccatggatacccctccatgcctcaaggtgacccacaagacattcggcacccagaac agcagtgccaccatgatctactgccgcctgagcgtgcccgtcgagtgccactcctccttc agtcacagcccctgtctggacagtgatgccttccagaaaaggaaacagatgcaagaaata ctctctcacacaacaacacagtgctactatgcaatccgcatctttgccggacaggacccc tcctgcgtgtgggtcggatgggtgactccggattatcacttgtacagtgaaaagtttgac ctgaataaaaactgtactgtgactgttactctgggggacgaaagaggccgagtccacgaa agcgtgaaacgcagcaactgctacatggtgtggggtggagacatcgtggctacatcccaa agagcgagtcgcagcaatgtggacctggagatcggctgcctcgtggatctggcgatgggc atgctgtccttttcagccaacgggagggaacttggcacctgctaccaggtggagcccaat accaaagtgtttccagccgtcttcctgcagcccacaagcacctctctgtttcaatttgaa cttgggaagctgaagaatgccatgcccctgtcggcagccatatttaagagtgaagagaag aaccccgtcccgcagtgcccgccacggctggatgtccaaaccatccagcctgtgctctgg agccgcatgcccagcagcttcctgaaggtggagacggagagggtgagcgagcgccatggc tgggtggtgcagtgcctggagcccctgcagatgatggcactgcacatcccggaagagaac aggtgtgtggatatcctggagctctgcgagcaggaggacctcatgcggttccattaccat acactgagactctacagcgccttgtgtgccctgggaaacagccgggtggcctacgccctg tgcagccacgtggacctctcccaacttttctatgccattgacaacaagtacctccctggc ctcctgcgctcaggcttctatgacctgcttatcagcatccacctggccagcgctaaggag aggaagctgatgatgaagaatgagtacatcatccccatcaccagcaccatcaggaaaatc cgcctgtacccggatgagtccaagaggcatgggctccctggggtgggcccgagaacgtgc ctcaagccagggttcaggttctccaccccctgcttcatcaccaccaacgaggagcaccag aagcagagccccgagattcccttggagcttctcaagacgaaggcgctgggcatgctgacg gaggcagtgcagtgcagcggggctcacatccgggaccctgtcggggggtccgtggagttc cagtttgtgcctgtgctgaagctcatcggaaccctgctggtcatgggggtgtttgatgat gatgacgttcggcagatcctcctcctcatcgacccctctgtgtttggggagcacagtggg gagacagaggagggaggagagaaggaggaggtgacacaggtggaggagaaggctgtggag gctggggaaaaggccagcagggaggctcccatcaaaggcttgttgcagacccgattaccg gagtcagtcaagctgcagatgtgtgagctgctcagctatctctgtgactgtgagctgcag caccgggtggaggccattgtggccttcggtgacatctatgtctccaagctccaggaaaat cagaagttccgctacaacgagctcatgcaggccctgaacatgtctgcagccctgaccgcc cggaagaccagggagttccgctcgcccccacaggaacagatcaacatgcttcttaacttt caactgggggagaactgcccatgcccagaagaaatccgggaagagctgtatgacttccat gaggaccttctccttcactgcggggttcccctggaagaagaggaagaggaggaagaggat acctcctggactggaaaattctgtgccttggtgcagagaatcaaaggccctcccaagcca gagaaggagcaaccaacggaggaagaagagagatgccctacgaccctgaaggagctcatc tcacagaccatgatccgctgggcccaggaggaccagatccaggatgcagagctggtccgg atgatgttcaaccttctgcggcggcagtacgacagcatcggggagctgctgcaggcgctg cgcaagacctataccatcagccaggcctccgtgagcgacaccatcagcctgctagccgcc ctgggccaaattcgctgcctgctcagcgtcaggatgggcaaggaggaggagctactcatg atcaacgggctgggagacataatgaacaacaaggtgttttaccagcaccccaacctcatg agagtcctcggcatgcatgagacagtcatggaggtgatggtgaacgtgctgggtgcagaa aagtctcagattgcctttccaaagatggttgctagctgttgccgcttcctgtgctatttc tgtcgaatcagccgacaaaatcagaaggccatgtttgagcacctaagttacctgttggag aacagcagtgttggcctagcttccccctcgatgagaggatccaccccgctggatgtggcc gcttcctccgtgatggacaacaatgagttagcgctgggcttagaggagccagacctcgag aaggtggtgacctacttggcaggctgtggactacagagctgccccatgcttctagccaaa ggataccctgatgtcggctggaaccccattgaaggggagcgctacctgtccttcctgagg tttgccgtcttcgtgaacagtgaaagtgtggaagaaaatgctagtgtggtggtcaagctg ctcatcagacgtcccgagtgcttcggccccgccctgcggggtgaaggaggaaacggtctg ttggcggccatgcaaggcgccattaagatctccgagaacccagccctcgacctcccctca cagggctacaagagggaagtcacagaggacgatgaagatgaagaagagattgtgcacatg ggcaacgcaatcatgtcattttattcggctcttatagacctgctgggccgctgtgctcct gagatgcaccttatccagacagggaagggagaagccatccggatcaggtccatcctgcgc tccctggttcccactgaggacttggttggaatcatcagcatccccttgaaactgccttcc ctgaacaaagatgggtcagtcagtgagccagacatggcagccaacttctgccctgaccac aaggcgcccatggtactgttcttggaccgtgtgtatggcatcaaggatcaaacttttctg ctccacttgctggaagttggatttttacctgacctaagagcctctgcctctctagataca gtttccctaagcaccaccgaggcggcgctggcactgaacaggtacatatgttctgctgtg ctcccgctcctcacaagatgcgcccctctctttgccgggacagaacactgcacttctttg attgactctacactgcagacaatatacaggctttccaaggggcgatccctcaccaaagct cagagggacaccatagaggagtgtctgctggccatctgcaatcacttgagaccttccatg ttacagcaactcctgcgacgtctagtttttgatgtgccccaactcaatgaatactgcaaa atgcctcttaagcttctgacgaatcactacgaacagtgctggaagtattattgtctgcct tcgggctgggggagctacggtctggccgtggaggaagagctacatctgacagagaagctc ttctgggggatttttgactccctctcccataagaggtatgacccagatcttttccggatg gccctgccctgtctcagtgcaatagcgggggccctgccaccagattatttagataccaga atctcagccacattggagaaacaggtctcagtggacgcagatggcaactttgaccccaaa cccatcaacaccgtgaacttctccttgcctgaaaaattggaatacatcgtcaccaagtat gctgagcactcccatgataaatgggcctgtgacaagagtcagagtggatggaaatacgga atttccctggatgaaaatgtgaagacccatccattgatccggcctttcaagacattaacc gagaaggagaaggaaatttatcgctggcctgccagagagtccctgaaaaccatgctggct gtaggctggactgtagagaggaccaaagagggagaagctctggtgcaacagcgggaaaat gagaagcttcgaagcgtgtcccaggccagccagggcaacagctacagccctgcccctctg gatctctccaatgtcgtgctctccagagagctccaggggatggtggaggtggtagctgag aactatcacaatatctgggccaagaagaagaagctggagctggagagcaaaggtggcggc agtcaccctcttttggtaccctatgataccttgactgccaaggaaaagttcagagaccga gagaaggcccaggacctgtttaaattcctccaagtgaatggcattgtggtttccagaggt gtgaaggatatggagctggatgcctcctccatggaaaagaggtttgcctataagtttttg aagaaggttctgaaatatgttgattcggctcaagagtttattgcccatttggaagccatt gtcagcagtgggaaaaatgaaaagtctccccatgaccaggagatcaaattctttgccaaa gttctcctcccactggttgaccagtacttcaccaatcatcgcctctacttcctgtcctcc cctctgaagccccttagcagcagcgggtatgcctcccataaggagaaagaaatggtggcc agcctgttctgcaaactcgctgctctagttcgacacaggatttctctcttcgggagcgat tctgcgacaatggtgagctgtcttcacatcttagctcagacacttgacacaaggacggtc atgaagtcaggctcagagctggtgaaagccgggttacgggcgttctttgaaaatgcagcg gaagacttagagaagactttggaaaacctgaagctcggcaagtttacccattccagaacg cagatcaaaggtgtctctcaaaatattaactacactacggtggctctgctccccatcttg acatccatctttgagcacgtggctcagcatcagttcggggtggacttactcttgggtgac gttcagctctcatgctaccatatactgtgcagcctctactccctcgggacaggaaagaac atctatgttgaaaggcagcgtcctgcccttggagaatgcctggcctcactggcagccgcc ataccagtggcattcctggagcccacccttaaccgctacaacccgctctccgtcttcaac accaaaacccccagggagaggtctattctggggatgccagacacagtggaggagatgtgc cccgacatcccccagctggaaggcctgatgaaggaaatcaacgacctggctgagtcaggg gcccggtacacagagatgccccacgtcattgaggtcatcttgcccatgctgtgcaactac ctgtcctactggtgggagcgggggcccgagcacctgccccccagtgcagggccctggtgc accaaggtcacgtctgaacacctcagtgtcatcctgggcaacattctgaaaatcatcaac aataacctgggcattgatgaggcctcttggatgaagcgcattgcagtgtacgcccaaccg atcatcagcaaagccaggccagacctgctgagaagccacttcatcccgaccctggagaag ctgaagaagaaggccatcaagaccgtgcaggaggaggagcagctgcgagctgacagcaag ggagacacgcaggaggccgagctgctcatcctggacgagtttgctatcctctgcagagac ctctatgccttctaccccatgctcatccgctacgtggacaacagcagatctaactggctc aaaagccccgatgcagactctgaccagctcttccgcatggtggcagagatcttcatcctg tggtgtaaatctcacaacttcaagagggaagagcaaaattttgtgattcagaacgaaatt aataatctggcatttttaactggagacagcaaaagcaagatgtcgaaatctggaggacag gaccaggagcggaagaagacaaagcggaggggagacttttattccatccagacctccctc atcgtggctgcgctcaagaaaatgctgcccattggtctgaatatgtgcaccccaggcgat caggagctgatctcccttgcaaaatcacggtacagctatagggacacagatgaagaggtg aaggaacatctgcggaataacttgcacttgcaggaaaagtctgatgatccagctgtaaag tggcaactgaacctatacaaggatgttttaaagagtgaagaaccttccaacccagaaaag acagtggagcgtgtgcagagaatttcagcagctgtcttccacctagagcaggtggagcag cctttgaggtccaagaaggcggtctggcataaactgctatcaaagcagcggaaacgggca gtggtggcctgtttcaggatggcccctctctacaacttgcccaggcaccgctctattaac ctcttcctccatggctatcagagattttggatagaaacagaggagtattcctttgaagag aaactagtacaggatttggctaaatctcccaaggtggaagaggaggaggaggaagaggtg gaaaagcagccagacccgcttcatcagatcatcctccactttagccgcaacgctctcacg gagaggagcaaactggaagacgaccctttgtacacctcctatgccagcatgatggccaag agttgtcagagtggggaagacgaagacgaggaggaagacaaggagaaaacatttgaagag aaagaaatggaaaagcagaaaaccctctatcagcaagcccggctgcatgagcgtggagcc gccgagatggtccttcagatgatcagcgccagcaaaggtgagatgagccccatggtggtg gagactctgaagttggggatcgccattctgaatgggggcaatgccggtgtgcagcagaaa atgctagattacctaaaggagaaaaaggatgctgggttctttcaaagtctttctggtctt atgcagtcttgcagtgtccttgatttgaatgcatttgagaggcagaataaagctgaaggc ctggggatggttactgaggaaggaacactcattgttcgtgagcgtggtgaaaaagtactc cagaatgacgagtttacacgggatctctttagattcctacagttactttgtgaaggacat aacagtgatttccagaacttcctgaggacacagatgggcaacaccaccaccgtgaatgtc atcatcagtaccgtggactaccttctgcgtctgcaggaatcaatcagtgatttctactgg tattactcagggaaggacatcattgatgaatctggacagcacaatttttccaaagccctg gcagtcaccaagcagatcttcaattcgcttacagaatacatccagggcccctgcattggg aaccagcagagcctggctcacagcaggctgtgggacgcagtggtcggcttcctccatgtg tttgctaacatgcaaatgaaactctcccaggattccagtcagatcgagctgctgaaggaa ctcttggatctccttcaggacatggtggtgatgcttctgtccctcctggaagggaatgtg gtaaatggaaccattggcaagcagatggttgacacactggtagagtcatctaccaatgta gaaatgatcttgaaattctttgacatgttcttgaaacttaaagacttaaccagctcagac gccttcaaagaatatgaccccgacgggaaaggaatcatttccaaaaaggaattccagaag gccatggaagggcaaaagcagtacacacagtcggagacagactttctcctttcgtgcgca gaagctgatgaaaatgacatgtttaattacatcgattttgttgaccggttccatgagcca gccaaggacatagggtttaatgtggcggtgttattgaccaacctctctgagcatatgcca aacgattctcgccttaagtgtctgttggacccagcagaaagtgtactcaattacttcgaa ccatacctgggacgcattgagatcatgggtggggccaagaaaattgagcgtgtttatttt gagatcagtgagtccagtcgaacccagtgggagaagccccaagtgaaggagtctaagcga cagttcatctttgatgttgtcaatgaaggcggggagcaagagaaaatggagctgttcgtg aacttctgtgaggacaccatctttgagatgcagttagcatcgcagatctcggaatctgac tcagccgacaggccagaggaggaggaggaagaagatggagattcttcgtacgtgttagaa gtggagggtgaggaggaggaggagaagtcttttgagtgtgcctctgcatttgcgatggct tgcgcctcggtgaagagaaacgtggccaactttctgaagagggccaccctgaagaacctc aggaagcagtacaggaaggtgaagaagatgaccttcaaggagctggtgaagctgttcttc tctttcttctggacgttgttcgtggggctcttccacttgctcttcactatagtaggagga atcattcaggtcctctggagcaccgtgtttggagggggactcatagaaggggcaaagaat ataagagtcaccaagatcctgggcgacatgcctgacccaacccagtttggtatccacgat gatgctatggaagctgagagggcagaagtgcctgagccaggcctcaccacggaactcgtg cacttcgtaaagggggagaagggagatgcagacatcatgtcagatctctttggactccac ccaaagaaagaaggtggcttaaagcatgggcccgaagtgggtttgggtgacctctctgag attattggcaaggacgaaccccctaccttagagagtactgtccggaagaaaaggaaagca caggcagcagaaatgaaagcgtctcatgaagcagaaggaaaaatagagtctgagaaggca gacatggaagatggggagaaagagcacacagccaaagaagagcaggccgaggccctgtgg gcagacgtgaccaaaaggaagaagcgacggtgtggccagaaggttgagaagcctgaagcc ttcatggccaatttctttaaagggctggaaatctatcagaccaagttgctgcactacctg gccaggaatttctacaacctgaggttccttgctctgtttgtagccttcgctatcaacttc atcctgcttttttacaaggtcaccgaagaacctttagaagaagagacagaggatgttgca aacctgtggaattcctttaatgacgaggaagaggaagaggcggtggtgttctttgtcctg caggagagcactgggtacatggcgccagccctgcgggccctggccatcatccacaccgtc atctctttagtctgcgtggtgggctactactgcctaaaggtccctttggtcgtattcaaa agagaaaaagaaatcgccaggaagctggagtttgatggcctgtatatcactgaacagcct tctgaagatgacatcaaggggcagtgggatcgcttggtcatcaacacgccatcttttcct aataactactgggacaagtttgtaaagagaaaggtgatcaacaaatatggagatctctac ggagcagaacgcattgctgaactcctgggtttggacaaaaatgcccttgactttagccca gtggaagagaccaaagcagaggcggcctccctggtgtcatggctaagttccatcgacatg aagtaccatgtctggaagctgggagttgtttttactgacaattcctttctctacctcgcc tggtacacgaccatgtcagtcctgggccactacaacaactttttcttcgctgctcatctt ctggatatcgcgatgggcttcaagaccctgaggactattctgtcatctgtcactcacaat ggcaaacagctggtcctgaccgtcggtctcctggccgtggtggtttatctctataccgtg gttgccttcaacttcttccgcaagttctacaacaaaagtgaagacgatgacgagcccgac atgaagtgtgatgacatgatgacgtgttacctgttccacatgtacgtgggagtgagagct ggaggtggcatcggggatgaaattgaagaccctgctggggacccatatgaaatgtatcgc atcgtttttgacattaccttcttcttcttcgtcattgtcatcctgctagccatcatccaa ggtcttattattgatgcttttggggagctgagagaccagcaggaacaagtacgagaggat atggagactaaatgtttcatctgtgggattggcaatgactactttgacacgacccctcat ggttttgaaacacacacactgcaagagcacaacttagccaactacctgttcttcctcatg tatttgattaacaaagatgagacagagcacacgggacaggaatcttacgtctggaagatg taccaagaaaggtgctgggatttcttcccagctggtgactgcttccggaaacaatatgaa gatcagcttggataa

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