Oryx dammah (scimitar-horned oryx): 120853482 Help Entry 120853482         CDS       T07255                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda00230   Purine metabolism oda01100   Metabolic pathways oda01522   Endocrine resistance oda04015   Rap1 signaling pathway oda04020   Calcium signaling pathway oda04022   cGMP-PKG signaling pathway oda04024   cAMP signaling pathway oda04062   Chemokine signaling pathway oda04072   Phospholipase D signaling pathway oda04081   Hormone signaling oda04082   Neuroactive ligand signaling oda04114   Oocyte meiosis oda04211   Longevity regulating pathway oda04213   Longevity regulating pathway - multiple species oda04261   Adrenergic signaling in cardiomyocytes oda04270   Vascular smooth muscle contraction oda04371   Apelin signaling pathway oda04540   Gap junction oda04611   Platelet activation oda04713   Circadian entrainment oda04714   Thermogenesis oda04723   Retrograde endocannabinoid signaling oda04724   Glutamatergic synapse oda04725   Cholinergic synapse oda04727   GABAergic synapse oda04742   Taste transduction oda04750   Inflammatory mediator regulation of TRP channels oda04911   Insulin secretion oda04912   GnRH signaling pathway oda04913   Ovarian steroidogenesis oda04914   Progesterone-mediated oocyte maturation oda04915   Estrogen signaling pathway oda04916   Melanogenesis oda04918   Thyroid hormone synthesis oda04921   Oxytocin signaling pathway oda04923   Regulation of lipolysis in adipocytes oda04925   Aldosterone synthesis and secretion oda04926   Relaxin signaling pathway oda04927   Cortisol synthesis and secretion oda04928   Parathyroid hormone synthesis, secretion and action oda04934   Cushing syndrome oda04935   Growth hormone synthesis, secretion and action oda04970   Salivary secretion oda04971   Gastric acid secretion oda04972   Pancreatic secretion oda04976   Bile secretion oda05032   Morphine addiction oda05163   Human cytomegalovirus infection oda05166   Human T-cell leukemia virus 1 infection oda05200   Pathways in cancer oda05207   Chemical carcinogenesis - receptor activation oda05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oda00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     120853482 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     120853482 (ADCY4)    04371 Apelin signaling pathway     120853482 (ADCY4)    04020 Calcium signaling pathway     120853482 (ADCY4)    04072 Phospholipase D signaling pathway     120853482 (ADCY4)    04024 cAMP signaling pathway     120853482 (ADCY4)    04022 cGMP-PKG signaling pathway     120853482 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     120853482 (ADCY4)    04081 Hormone signaling     120853482 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     120853482 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     120853482 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     120853482 (ADCY4)    04062 Chemokine signaling pathway     120853482 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     120853482 (ADCY4)    04923 Regulation of lipolysis in adipocytes     120853482 (ADCY4)    04912 GnRH signaling pathway     120853482 (ADCY4)    04913 Ovarian steroidogenesis     120853482 (ADCY4)    04915 Estrogen signaling pathway     120853482 (ADCY4)    04914 Progesterone-mediated oocyte maturation     120853482 (ADCY4)    04921 Oxytocin signaling pathway     120853482 (ADCY4)    04926 Relaxin signaling pathway     120853482 (ADCY4)    04935 Growth hormone synthesis, secretion and action     120853482 (ADCY4)    04918 Thyroid hormone synthesis     120853482 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     120853482 (ADCY4)    04916 Melanogenesis     120853482 (ADCY4)    04925 Aldosterone synthesis and secretion     120853482 (ADCY4)    04927 Cortisol synthesis and secretion     120853482 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     120853482 (ADCY4)    04270 Vascular smooth muscle contraction     120853482 (ADCY4)   09154 Digestive system    04970 Salivary secretion     120853482 (ADCY4)    04971 Gastric acid secretion     120853482 (ADCY4)    04972 Pancreatic secretion     120853482 (ADCY4)    04976 Bile secretion     120853482 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     120853482 (ADCY4)    04727 GABAergic synapse     120853482 (ADCY4)    04725 Cholinergic synapse     120853482 (ADCY4)    04723 Retrograde endocannabinoid signaling     120853482 (ADCY4)   09157 Sensory system    04742 Taste transduction     120853482 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     120853482 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     120853482 (ADCY4)    04213 Longevity regulating pathway - multiple species     120853482 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     120853482 (ADCY4)    04714 Thermogenesis     120853482 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120853482 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     120853482 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120853482 (ADCY4)    05163 Human cytomegalovirus infection     120853482 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     120853482 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     120853482 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     120853482 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     120853482 (ADCY4) Enzymes [BR:oda01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      120853482 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  120853482 NCBI-ProteinID:  XP_040083289 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MARLFSPRQPPSEDLFYETYYSLSQQYPLLLLLLLIVLLGLLALLPVAWASGRELAADPA FLTTVLCALGGFSLLLVLASREQRLQRWTRPLSGLVWAALLALGHSLLFTGGVVSAWDQV SFFLFVIFTVYAMLPLDMRDAITAGVTTSLSHLLVLGLYLGPQPNSRPALLPQLAANAVL FLCGNAAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK EEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPWAAEEDEKGTAGGLLSSLEGPTMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTMRALDEELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALTITYSITFLLFFLLLFVCFSEHLMKCVLKGPKMLHWLPTLSVLVATRP GLRVALGTAAILLVFLMAITSLVFLPAASACPFQAPNVSSMASNLSWEIPGSMPLISVPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWVTASCSVFLHSHAWLSDCLIARLYLGTLDS RPGVLKEPKLMGAASFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNAASGQDAQQDAEQSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggcagccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctgctgctgctgctgatcgtgctcttgggg ctcctggcgttgctccctgtggcctgggcaagtggcagggagctggccgcagacccagcc ttcctgaccactgtgctgtgcgctctgggcggcttctcactgctgctggtcctggcttcc cgggagcagcgactgcaacgctggacacgtcccctgtcaggcctcgtgtgggcagcactg ctcgcactgggccacagcctcctgttcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctttttgtcatcttcactgtgtatgccatgttgcccttggacatgagggac gccatcaccgcgggggtcaccacctcactctcacacctgctggtccttggactgtatctc gggcctcagcccaactctcggccggcgctgctaccacagctggctgcaaacgcggtgctg ttcctgtgcgggaacgcggccggagcctatcacaaggcgctgatggagcgcgcgctgcgc gccacgttccgggaggcgcttagttccctgcactcgcggcggagactggacactgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag gaggagatcatggcacgactgcaggctggacaggggtcacggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgcgactggccagtgagtgctcccctaaggagttggtgcttatgctcaacgag ctctttggcaagttcgaccaaatcgccaaggagcacgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctctgggctgccgctctcactgccagaccacgccatcaat tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccacgggc gtggatatcaacatgcgtgtgggcgtgcactcaggcagcgtgctctgcggggtcatcggg ctacagaaatggcaatatgatgtctggtcccatgatgtcactctagccaaccacatggag gcgagtggagtgccaggacgagtacatatcacaggggccacgctggccctgctggccggg gcttatgctgtggaggacgcagccatggaacaccgggacccataccttcgggagctaggg gagccgacctacctggtcatcgacccctgggctgcagaggaggatgagaagggcactgca ggagggttgctgtcctctctggagggccccacgatgcgtccgtccctgctgatgacccgc tacctggagtcctggggtgcagccaagcctttcgcccacctgagccatgtagagagccct gtgtccacgtctacccctctcccggagaaggccctgtcttccttcagcccccagtggagc ctggaccggagccgtaccatgcgggcacttgacgaggaactagacactggggatgccaag ttcttccaggtcatcgaacagctcaattctcagaaacagtggaaacagtcaaaggacttc aatccactgacactgtacttcagagagaaggagatggagaaagagtatcggctctctgca ctccccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaacttcatt atccagatgctggtgacaaacaggcctccagctctgaccatcacctatagcatcaccttc ctcctcttcttcctcctcctcttcgtctgcttctcagagcatctgatgaagtgtgtcttg aaaggccccaagatgctgcactggctgcccaccctgtctgtcctggtggccacacggcca ggactgcgagtggctctgggcaccgctgccatcctgctcgtcttcctcatggccattacc agcctggtcttcttaccagcagcatcagcctgccctttccaggctcccaatgtatcctcc atggcttccaacctctcctgggagatccctgggtccatgcctctcatcagcgtcccgtac tccatgcactgctgcgtgttggggttcctgtcctgctccctcttcctgcacatgagcttt gagctgaagctgctgctgctcctgctgtgggtgacggcctcctgctccgtcttcctgcac tcccacgcctggctgtccgactgcctcatcgcccgcctctacctgggcaccttggactcc aggccaggggtgctgaaggagcccaaactgatgggagcagcctccttcttcatcttcttc ttcaccctcctagtcctggctcggcagaatgaatattactgccgcctggactttctgtgg aagaagaagctgaggcaagagcaggaggagacggagacgatggagaacctgactcggctg ctcttggagaacgtgctccctgcccacgtggccccccagtttattggtcagaatcggcgc aatgaggacctctaccaccagtcctatgagtgtgtgtgtgtcctcttcgcctcggtccca gactttaaggagttctactctgaatccagcatcaaccacgaggggctagagtgtctgcgg ctgctcaatgagataatcgctgattttgatgagctgctctccaagcccaagttcagtggg gtggagaagatcaaaaccatctgcagcacctacatggcagctaccggcttgaacgccgcc tctgggcaggatgcacagcaggatgctgagcaaagctgcagccaccttggcaccatggta gagtttgctgtggcccttggatctaagctggatgtcatcaacaagcactcattcaacaac ttccgcttgcgtgtagggttaaaccacggacctgtagtggctggagtgatcggggcccag aaaccacaatatgatatctggggcaacacggtgaacgtggccagccgcatggagagcaca ggcgtcctgggcaagattcaggtaacagaagagacagcctgggccctgcagtccttaggc tacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctac ttcttgaacacagatttgacacgaactggacctccctcagccaccctaggctga

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