Oryx dammah (scimitar-horned oryx): 120854436
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Entry
120854436 CDS
T07255
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
oda
Oryx dammah (scimitar-horned oryx)
Pathway
oda00230
Purine metabolism
oda00670
One carbon pool by folate
oda01100
Metabolic pathways
oda01523
Antifolate resistance
Module
oda_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
oda00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
120854436 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
120854436 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
120854436 (GART)
Enzymes [BR:
oda01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
120854436 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
120854436 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
120854436 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
ATP-grasp_3
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_4
RimK
Motif
Other DBs
NCBI-GeneID:
120854436
NCBI-ProteinID:
XP_040084373
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALVQ
FCKDEKIEFVVVGPEAPLAAGIVGNLSSEGVRCFGPTAEAAQLESSKRFAKEFMDRHGIS
TARWRAFTKPEKACDFIMSADFPALVVKASGLAAGKGVVIAKSKEEACEAVREIMQGKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVVQSTLDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEA
RALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQTRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKIAQQCGKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLHTTEAVIAGIAQACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPVGCGDQTLGDLLLTPTR
IYSHLLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPGIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEH
LIETMQINGSELENGALRNHYSVQRKKARVAVLISGTGSNLQALIDSTREPSSLAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKNRAAFDSAVDEVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVCLGENGRICWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcagtggaggacgggaacacacgctggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaatactgacatctcaatcagtgatcatactgcccttgtgcag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctagctgct
ggaattgttgggaacctgagctctgagggagttcggtgctttggccccacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatctca
acagcaagatggagagcgttcactaaacctgaaaaagcctgtgacttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtagttatt
gccaagagcaaagaggaggcatgtgaagctgtcagagagattatgcagggtaaagctttc
ggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggacggactgtggcgcccatgcccccagcacaggaccataagcga
ttgctggagggcgatcagggccccaacacggggggaatgggagcctactgtccagcccct
caggtttctaaggatttgttgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcaggaggagggtatgccatacacaggtgtcctctatgctggtataatgctgacc
aagaacggccccaaagttctggaatttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtggttcagtctaccttagatggcttg
ctctgcacatctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaaaggtgtagagataacagggtttcctgaggct
cgggctttaggactggaggtgttccaagcaggcactgccctaaaagatggcaaggtggtg
actaacgggggtagggtcctcactgtcacggccatcagggaaaatctcatctcagccctt
gaagaagccaggaaaggacttgccgctataaagtttgagggagctgtttataggaaagac
atcggctttcgagccatagctttcctccagcagaccaggggcctgacttacaaggaatct
ggggtagacattgcagctggtaatatgctggtccagaaaattaaacctttagcgaaggcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcctgtggaacagatggcgttgggacgaaactg
aagattgcccagcagtgcggtaaacatgacaccattggtcaggatttggttgcgatgtgt
gtaaatgacattctggcacaaggagcagagcctctctttttccttgattacttttcctgt
ggaaaacttgacctccatacgactgaagctgttatcgctgggatcgcccaagcttgtaga
aaagctggatgtgctctcctcggaggtgaaacggcagagatgcctgacatgtaccctcct
ggagagtatgatctagctggttttgctgttggcgccatggagcgggatcagaaacttcct
cacctggaaagaatcacggaaggggacgctgttattggaatcgcctcatctggtcttcac
agcaacggattcagccttgtgaggaaaattgtagcaaaatcttccctccagtactcttct
ccagcacctgttggttgtggtgaccagaccttaggtgacttacttctaaccccaaccaga
atctacagccacttgctgttacctgtcctgcgttcaggacgtgttaaggctgttgcgcat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaactgggggtg
aatttagatgcccagacctggagggtccccgggatcttctcatggttacagcaggaaggc
cacctctctgaagaggagatggccagaacatttaactgtggcattggggctgccctcgtg
gtatcagaggacctggtgaagcagactctgcaggatattgagcagcaccaggaagaagcc
tgggtgattggcagagtggttgcgtgtcccgaaggttctcctcgtgtgaaagttgagcat
ctgattgaaaccatgcaaataaatggatcagaactggagaatggagccctgagaaatcat
tactctgttcaacggaaaaaggcaagagtagctgtcttaatatctgggacaggatcgaac
ctccaagctctcatagacagcactagggagccaagtagcttggcacacattgtcgttgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccgggattcccacc
agagtaattaaccataaattatataaaaatcgtgcagcatttgacagtgcagttgacgaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggccccttcgtcagaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcgtttaagggctcaaatgcccatgaacaagtcctggacgctggggtcacaatcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggtcaaattatcttacaggaagcc
gttccagtgaagaggggtgacactgttgaaactctatctgagagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggagctgtatgtcttggagaa
aatggcagaatctgttgggtcaccgaggactga
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