Oryx dammah (scimitar-horned oryx): 120857038 Help Entry 120857038         CDS       T07255                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda01521   EGFR tyrosine kinase inhibitor resistance oda04151   PI3K-Akt signaling pathway oda04217   Necroptosis oda04380   Osteoclast differentiation oda04550   Signaling pathways regulating pluripotency of stem cells oda04620   Toll-like receptor signaling pathway oda04621   NOD-like receptor signaling pathway oda04630   JAK-STAT signaling pathway oda04658   Th1 and Th2 cell differentiation oda04659   Th17 cell differentiation oda05140   Leishmaniasis oda05145   Toxoplasmosis oda05152   Tuberculosis oda05160   Hepatitis C oda05161   Hepatitis B oda05162   Measles oda05163   Human cytomegalovirus infection oda05164   Influenza A oda05165   Human papillomavirus infection oda05166   Human T-cell leukemia virus 1 infection oda05167   Kaposi sarcoma-associated herpesvirus infection oda05168   Herpes simplex virus 1 infection oda05169   Epstein-Barr virus infection oda05171   Coronavirus disease - COVID-19 oda05200   Pathways in cancer oda05203   Viral carcinogenesis oda05212   Pancreatic cancer oda05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:oda00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     120857038 (JAK1)    04151 PI3K-Akt signaling pathway     120857038 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     120857038 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     120857038 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120857038 (JAK1)    04621 NOD-like receptor signaling pathway     120857038 (JAK1)    04658 Th1 and Th2 cell differentiation     120857038 (JAK1)    04659 Th17 cell differentiation     120857038 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     120857038 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120857038 (JAK1)    05203 Viral carcinogenesis     120857038 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     120857038 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     120857038 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120857038 (JAK1)    05161 Hepatitis B     120857038 (JAK1)    05160 Hepatitis C     120857038 (JAK1)    05171 Coronavirus disease - COVID-19     120857038 (JAK1)    05164 Influenza A     120857038 (JAK1)    05162 Measles     120857038 (JAK1)    05168 Herpes simplex virus 1 infection     120857038 (JAK1)    05163 Human cytomegalovirus infection     120857038 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     120857038 (JAK1)    05169 Epstein-Barr virus infection     120857038 (JAK1)    05165 Human papillomavirus infection     120857038 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     120857038 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     120857038 (JAK1)    05140 Leishmaniasis     120857038 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     120857038 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oda01001]     120857038 (JAK1) Enzymes [BR:oda01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      120857038 (JAK1) Protein kinases [BR:oda01001]  Non-receptor tyrosine kinases   JAK family [OT]    120857038 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  120857038 NCBI-ProteinID:  XP_040088602 LinkDB All DBs Position Unknown AA seq 1158 aa AA seqDB search MQYLNIKEDCSAMAFCAKMRSSKKAEMNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVADATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKVQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDSGNVLCYEVMVTGNLGIQWRQKPHIVPVEKEKNKLKRKKLENKHKKDEEKNKIR DEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAVNKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEALGIQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDITQGEHLGRGTRTHIYSGT LTDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQHMRKCWEFQPSNRTT FQNLIEGFEALLRSMCSN NT seq 3477 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcagtgccatggctttctgtgctaaaatgagg agctccaagaaggcggagatgaatctagaggcccctgagccgggggtggaggtgctcttc tacctgtcggatagggagcctctccggctgggcggcggagagtacacagcggaggagctg tgcatccgggcggcgcaggagtgctgtatctctcctctgtgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcactgtcgacgacaaa acatcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gacaacgaacagtcagtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagttgcagatgcaacccctctccttgacgccagctcactggagtatctgtttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag gatggacacgacattgagaacgagtgtctggggatggccgtgctggccatctcccactac gccatgatgaagaaggtgcaattgccagaactccccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgcgacagcagc gtgtccacgcacgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat cggttccatccaaatgatagtggaaatgttctctgctatgaagtgatggtgactggaaac cttggaatccagtggagacagaaaccacatattgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggaaaaaaacaaaatccga gatgagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgag gaggccttgtccttcgtgtccctggtggacggctacttccggctcacggcagacgcccat cactacctctgcactgatgtggctcccccgctgattgtccacaacatacagaatggctgt catggtccgatctgcacggagtatgctgtcaataagctgcggcaggaggggagcgaggag gggatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcacc tgcttcgaaaagtctgaggcgctgggtatccagaaacagttcaagaactttcagatcgag gtacagaagggccgctacagcctgcatggctcggaccgcagcttcccaagccttggggac ctcatgagccacctaaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag cgctgctgtcagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc caggagtggcagcctgtctaccccatgagccagctgagtttcgatcgaatcctcaagaaa gatattacacaaggtgagcaccttgggagaggcacgcggacacacatctactctgggacc ctcacggattacaaggatgatgaagggacttctgaagagaagagaataaaagtcatcctg aaggtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg atgaggcaggtctcccataaacacatcgtgtacctctatggggtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggaggggggacccctggatctctttatgcatcgg aaaagtgatgtcctcaccacaccctggaagtttaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagacctggtccatggaaacgtgtgcaccaaaaacctcctt ctggcccgtgagggcatcgacagtgagtgtggccccttcatcaagctcagtgaccctggc atccccatcactgtgctctccaggcaagagtgcatagaacgaatcccctggatcgctccc gagtgtgttgaagactccaagaacctgagtgtggctgctgacaagtggagctttggaacc acactctgggaaatctgctacaatggcgagatccccttgaaagacaagacgctgattgag aaagagagattctacgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct gacctgatgacccgctgcatgaactacgaccccaaccagaggcccttcttccgagccatc atgagagacatcaacaagctggaggagcagaatccagacattgtatcagaaaaaaagcca gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggataataca ggggagcaggtggctgtcaaatccctgaagcccgagagtggagggaaccacatcgctgat ctgaagaaggagattgagatcttaagaaatctttatcatgagaacatcgtgaagtataaa ggcatctgcacagaagacggtggaaatggtattaagctcatcatggagtttctgccttca gggagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatatgttcac cgggacttagcagcaagaaacgtccttgttgagagtgaacaccaagtgaaaattggggac tttggtctaaccaaagccatcgaaactgataaggagtactacacagtcaaggacgaccgg gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc tctgatgtctggtctttcggagtgactctgcatgagctgcttacttattgtgattcagat tccagtcccatggccttgttcctgaaaatgataggcccaactcatggtcagatgacggta acaagactcgtgaatacattaaaagaaggaaaacgcttgccatgtccacctaactgtcca gatgaggtttatcaacatatgcgaaagtgttgggaatttcaaccatctaatcggacaacc tttcagaaccttatcgaaggatttgaagcacttctaagaagcatgtgtagtaactaa

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