KEGG   Oryx dammah (scimitar-horned oryx): 120857807
Entry
120857807         CDS       T07255                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
oda  Oryx dammah (scimitar-horned oryx)
Pathway
oda01522  Endocrine resistance
oda04010  MAPK signaling pathway
oda04015  Rap1 signaling pathway
oda04068  FoxO signaling pathway
oda04071  Sphingolipid signaling pathway
oda04114  Oocyte meiosis
oda04148  Efferocytosis
oda04218  Cellular senescence
oda04261  Adrenergic signaling in cardiomyocytes
oda04370  VEGF signaling pathway
oda04380  Osteoclast differentiation
oda04517  IgSF CAM signaling
oda04550  Signaling pathways regulating pluripotency of stem cells
oda04611  Platelet activation
oda04613  Neutrophil extracellular trap formation
oda04620  Toll-like receptor signaling pathway
oda04621  NOD-like receptor signaling pathway
oda04622  RIG-I-like receptor signaling pathway
oda04625  C-type lectin receptor signaling pathway
oda04657  IL-17 signaling pathway
oda04658  Th1 and Th2 cell differentiation
oda04659  Th17 cell differentiation
oda04660  T cell receptor signaling pathway
oda04664  Fc epsilon RI signaling pathway
oda04668  TNF signaling pathway
oda04670  Leukocyte transendothelial migration
oda04714  Thermogenesis
oda04722  Neurotrophin signaling pathway
oda04723  Retrograde endocannabinoid signaling
oda04728  Dopaminergic synapse
oda04750  Inflammatory mediator regulation of TRP channels
oda04912  GnRH signaling pathway
oda04914  Progesterone-mediated oocyte maturation
oda04917  Prolactin signaling pathway
oda04926  Relaxin signaling pathway
oda04932  Non-alcoholic fatty liver disease
oda04933  AGE-RAGE signaling pathway in diabetic complications
oda04935  Growth hormone synthesis, secretion and action
oda04936  Alcoholic liver disease
oda05014  Amyotrophic lateral sclerosis
oda05020  Prion disease
oda05022  Pathways of neurodegeneration - multiple diseases
oda05132  Salmonella infection
oda05133  Pertussis
oda05135  Yersinia infection
oda05140  Leishmaniasis
oda05142  Chagas disease
oda05145  Toxoplasmosis
oda05152  Tuberculosis
oda05161  Hepatitis B
oda05163  Human cytomegalovirus infection
oda05167  Kaposi sarcoma-associated herpesvirus infection
oda05169  Epstein-Barr virus infection
oda05170  Human immunodeficiency virus 1 infection
oda05171  Coronavirus disease - COVID-19
oda05205  Proteoglycans in cancer
oda05208  Chemical carcinogenesis - reactive oxygen species
oda05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oda05415  Diabetic cardiomyopathy
oda05417  Lipid and atherosclerosis
oda05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oda00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120857807 (MAPK12)
   04015 Rap1 signaling pathway
    120857807 (MAPK12)
   04370 VEGF signaling pathway
    120857807 (MAPK12)
   04668 TNF signaling pathway
    120857807 (MAPK12)
   04068 FoxO signaling pathway
    120857807 (MAPK12)
   04071 Sphingolipid signaling pathway
    120857807 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    120857807 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    120857807 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    120857807 (MAPK12)
   04218 Cellular senescence
    120857807 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    120857807 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    120857807 (MAPK12)
   04613 Neutrophil extracellular trap formation
    120857807 (MAPK12)
   04620 Toll-like receptor signaling pathway
    120857807 (MAPK12)
   04621 NOD-like receptor signaling pathway
    120857807 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    120857807 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    120857807 (MAPK12)
   04660 T cell receptor signaling pathway
    120857807 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    120857807 (MAPK12)
   04659 Th17 cell differentiation
    120857807 (MAPK12)
   04657 IL-17 signaling pathway
    120857807 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    120857807 (MAPK12)
   04670 Leukocyte transendothelial migration
    120857807 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120857807 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    120857807 (MAPK12)
   04917 Prolactin signaling pathway
    120857807 (MAPK12)
   04926 Relaxin signaling pathway
    120857807 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    120857807 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120857807 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    120857807 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    120857807 (MAPK12)
   04722 Neurotrophin signaling pathway
    120857807 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120857807 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120857807 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    120857807 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    120857807 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    120857807 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120857807 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120857807 (MAPK12)
   05161 Hepatitis B
    120857807 (MAPK12)
   05171 Coronavirus disease - COVID-19
    120857807 (MAPK12)
   05163 Human cytomegalovirus infection
    120857807 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120857807 (MAPK12)
   05169 Epstein-Barr virus infection
    120857807 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120857807 (MAPK12)
   05135 Yersinia infection
    120857807 (MAPK12)
   05133 Pertussis
    120857807 (MAPK12)
   05152 Tuberculosis
    120857807 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120857807 (MAPK12)
   05140 Leishmaniasis
    120857807 (MAPK12)
   05142 Chagas disease
    120857807 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120857807 (MAPK12)
   05020 Prion disease
    120857807 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    120857807 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120857807 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    120857807 (MAPK12)
   05415 Diabetic cardiomyopathy
    120857807 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120857807 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    120857807 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120857807 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    120857807 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oda01001]
    120857807 (MAPK12)
Enzymes [BR:oda01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     120857807 (MAPK12)
Protein kinases [BR:oda01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   120857807 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 120857807
NCBI-ProteinID: XP_040089527
LinkDB
Position
Unknown
AA seq 367 aa
MSSPSLARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSALDSRTGSKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQTLKGLKYIHAAGVIHRDLKPSNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVSLLEKMLVLDAERRV
TAAEALAHPYFESLHDTEDEPQAQKYDESFDDMDRTLDEWKRVTYKEVLSFKPPRQLGAK
ASKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgtcgcttgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcagcccgtgggctcgggcgcctacggcgcc
gtgtgctcggcgctggacagccgcacgggcagcaaggtggccatcaagaagctgtaccgg
ccctttcagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcacgcccgacgagacactggat
gacttcacggacttctacctggtgatgccgttcatgggcaccgacctgggaaagctcatg
aagcatgagaagctgagcgaagaccgggtgcagttcctcgtctaccagacgctcaagggg
ctgaagtacatccatgccgccggcgtcatccatagggacctgaagcccagcaacctggct
gtgaatgaggactgtgagctgaagatcctggacttcggcctggcccggcaggcagacagc
gagatgaccggctacgtggtgacccggtggtaccgcgcgcctgaagtcatcttgaactgg
atgcactacacgcagacggtggacatctggtccgtgggctgcatcatggccgaaatgatc
acagggaagacactcttcaaaggcaacgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctcccgcggagtttgtgcagaggctgcaaagtgacgaggccaagaac
tacatgaagggcctccctgagctggagaagaaggattttgcctccatcctgaccaacgca
agccccctggccgtgagcctcctggagaaaatgctggtgctggacgcagagcggcgggtg
acggcggccgaggcgctggcccatccctacttcgagtcactgcacgacacggaggacgag
ccccaggcccagaagtacgatgagtccttcgacgacatggaccgcacgctggatgagtgg
aagcgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gcctccaaggagacagccttgtga

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