Oryx dammah (scimitar-horned oryx): 120863977
Help
Entry
120863977 CDS
T07255
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
oda
Oryx dammah (scimitar-horned oryx)
Pathway
oda04217
Necroptosis
oda04380
Osteoclast differentiation
oda04620
Toll-like receptor signaling pathway
oda04621
NOD-like receptor signaling pathway
oda04630
JAK-STAT signaling pathway
oda04658
Th1 and Th2 cell differentiation
oda04659
Th17 cell differentiation
oda05145
Toxoplasmosis
oda05160
Hepatitis C
oda05161
Hepatitis B
oda05162
Measles
oda05164
Influenza A
oda05165
Human papillomavirus infection
oda05167
Kaposi sarcoma-associated herpesvirus infection
oda05168
Herpes simplex virus 1 infection
oda05169
Epstein-Barr virus infection
oda05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
oda00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
120863977 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
120863977 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
120863977 (TYK2)
04621 NOD-like receptor signaling pathway
120863977 (TYK2)
04658 Th1 and Th2 cell differentiation
120863977 (TYK2)
04659 Th17 cell differentiation
120863977 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
120863977 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
120863977 (TYK2)
05160 Hepatitis C
120863977 (TYK2)
05171 Coronavirus disease - COVID-19
120863977 (TYK2)
05164 Influenza A
120863977 (TYK2)
05162 Measles
120863977 (TYK2)
05168 Herpes simplex virus 1 infection
120863977 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
120863977 (TYK2)
05169 Epstein-Barr virus infection
120863977 (TYK2)
05165 Human papillomavirus infection
120863977 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
120863977 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oda01001
]
120863977 (TYK2)
Enzymes [BR:
oda01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120863977 (TYK2)
Protein kinases [BR:
oda01001
]
Non-receptor tyrosine kinases
JAK family [OT]
120863977 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
120863977
NCBI-ProteinID:
XP_040096666
LinkDB
All DBs
Position
Unknown
AA seq
1184 aa
AA seq
DB search
MPLCQWRTTTRGRKPNGDGAQPMTTREGLKVLLHWAGPSGGEPWVTFTEPTLTAEDVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGPETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMALLHLCHLALRNGVPLEKVAKKTSFKDCIPRSFRRQIRQHNALTRLRQRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLSQAEGEPCYIQDGGQA
PPDPGSESAAGPPTHEVLVSGTEGIQWRLVPAEGPADGGGSTMPDADPSGKKMKAKEAGG
EPVDRPRETPWSYFCDFQDITHVVLKECHVSLHCQDNKCLELTLPSRAAALSLVSLVDGY
FRLTTDSNHYLCHEVAPPRLVMSIQDGIHGPLLDPFVLAKLKPEAGLYLIHWSTSHLHRL
ILTVAQHDQLQAPGTKGLRLRKFPIELRAGTVMLEGWGRSFPSVRDLRAALQDCSLRAGD
DCFSLRRCCLPRPGEISNLIVTRGPQASTRPLNLSHLSFYRVRQEDITQLSHLGQGTRTN
VYEGLLRVGGGGPEEDKADGEEPLTPAGDRGQELRVVLKVLDPSHHDIALAFYETASLMS
QVSHVHLAFVHGVFVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLASALS
YLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTAPEC
LSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPELAT
LTSQCLTYEPAQRPSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFHKRYLKKIRDL
GEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIDILRTLYHKHIVKYK
GCCEDQGEKSVQLVMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHTQHYVHRD
LAARNVLLDNNRLVKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVLMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLMELLERGERLPQPERCPSE
IYCLMKDCWKAEASFRPTFQNLVPILRSYHEKYQGLAPSVFSVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggaggaccaccaccaggggcaggaagcccaatggggacggagct
cagcccatgaccaccagagaaggcctgaaagtacttctgcactgggctggccccagtggt
ggggagccctgggtcactttcactgagcccacactgaccgcggaggatgtctgcatccac
atcgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacatcctggatacctccagggactccagcctg
acgctgtacttccgcatgaggttttatttccgaaactggcatggcacaaatcctcaggag
ccggctgtgtaccgctgcgggcccccagggcctgagacttcctcagaacaggcagagcag
ggggtgcaactcctggaccctgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtaaatgacgtggcgtcactatgggagctatccagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccacctcgctctccgcaatggt
gtcccccttgaaaaggtggccaagaagaccagcttcaaggattgcatcccacgctccttc
cggcggcaaatccggcagcacaatgctctgacacggctgcgccaacggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggtcgtcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcctgtgtgccac
ctggagctgctgtcccaggccgagggggagccctgctacatccaggacggtgggcaggcc
cctcccgaccccgggtctgagtctgctgccggaccccccacccacgaggtgttggtgtca
ggcacggaaggcatccagtggcggctggtaccggcagaggggcctgctgatggtggcggc
agtacgatgcctgatgctgacccgtctgggaagaaaatgaaggccaaggaggcgggcggc
gagccagtggacaggcctcgggagaccccctggtcctacttttgtgacttccaggacatc
acccacgtggtgctgaaggaatgccacgtcagccttcattgtcaggacaacaaatgcctg
gagctgaccctgccttcccgggctgcggccctgtccttggtgtcgctggtggatggctac
tttcgcctgaccaccgactcaaaccactacctgtgccacgaggtggctcctccacggctg
gtgatgagtatccaggatggtatccatggccccctgctggatccattcgtgctggccaag
ctgaagcctgaggctggcctctacctaatccactggagcaccagccacctccaccgcctc
atcctcacagtggcccagcacgaccagctgcaggctcccggcaccaagggcttgcgcctg
cggaagttccccatcgagctccgggccgggacagtcatgctggagggctggggccggtct
ttccccagcgtgcgggacctgcgggccgccctgcaggactgctcgctgcgggccggcgac
gactgcttttccctgcgtcgctgctgcctgcctcggccgggagagatctccaacctcatc
gtcacacgggggcctcaggccagcaccagaccgctcaacctcagtcatctcagcttctac
cgagtccgccaggaagacatcacccagctgtcccacttgggccagggcacaaggaccaac
gtgtatgagggcctcttgcgagtggggggcggaggccccgaggaggacaaggcagatggc
gaggaacccctcacgcccgctggggaccgtgggcaggagctgcgtgtggtgctcaaggtg
ctagaccccagtcaccacgacatcgccctggccttctacgagacagccagcctcatgagc
caggtctcccacgtgcacctggccttcgtgcacggcgtcttcgtgcacggctccgagaac
atcatggtgaccgagtatgtggagcacgggcccctggacgtatggctgcggcgggagagg
ggccgcgtgcccctggcctggaagttggcagtggcccagcagctggccagcgccctcagc
tacctggaagacaaaagcctggttcatggcaacgtgtgtggccggaacatcctgctggca
cggctggggctagcggagggcaccagccccttcatcaagctgagcgaccccggcgtgggc
ctgagtgccctctccagggaggagcgggtggagcggatcccctggacagcccccgagtgc
ctatctggtggagccaacagcctgagcaccgcagccgacaagtggggctttggtgccacc
ctcctggagatctgcttcgacggtgaggcccccctgcagggccgcagtccctctgagaaa
gagcgcttctaccagaagcagcacaaactgcccgagccctcgtgcccagagctggccaca
ctcaccagccagtgcctgacctacgagccagcccagcggccatccttccgcaccatcctg
cgtgacttcactcagctacagccccagaatctcgctgatgtcttgtctgtgagcccggat
tctctggcttcagatcccacggttttccacaagcgatacttgaaaaagatccgggatctg
ggtgagggtcacttcggaaaggtcagcctgtactgctacgaccccaccaacgacggcact
ggtgagatggtagccgtgaaggctctcaaggcaggctgcggtccccagctccggacgggc
tggaggcgagaaatcgacatcctacgcacgctctaccacaagcacatcgtcaagtacaag
ggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggaatacatgcccctg
ggcagcctccgagactacttgccccggcacaatgtcgggctggtgcagctgctgctcttc
tccctgcagatctgcgagggtatggcctacctgcacacacagcactacgtgcatcgagac
ctggccgcgcgcaacgtgctgctggacaacaacaggctggtcaagatcggggacttcgga
ctcaccaaggccgtgcccgaaggccacgagtattactgcgtgcgcgaggatggggacagt
cctgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactacgcatcagac
gtctggtcctttggggtcctcatgtatgagctgctgacctactgtgactccagccagagc
cctccctcgaaattcatcgagctcataggcctcacccaagggcagatgactgtgctgagg
ctcatggagctgttggaacgaggggagaggctgccacaaccagagagatgcccctctgag
atatattgcctcatgaaggactgctggaaggcagaggcctcattccgcccgaccttccag
aacctcgtacccatcctcagatcataccacgagaaataccaaggcctggccccctcggtg
ttcagtgtctgctga
DBGET
integrated database retrieval system
