Oryx dammah (scimitar-horned oryx): 120864760
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Entry
120864760 CDS
T07255
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
oda
Oryx dammah (scimitar-horned oryx)
Pathway
oda00310
Lysine degradation
oda01100
Metabolic pathways
oda05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
oda00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
120864760 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
120864760 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
oda03036
]
120864760 (DOT1L)
Enzymes [BR:
oda01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
120864760 (DOT1L)
Chromosome and associated proteins [BR:
oda03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
120864760 (DOT1L)
HMT complexes
Dot1-containing complex
120864760 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
120864760
NCBI-ProteinID:
XP_040097781
LinkDB
All DBs
Position
Unknown
AA seq
1714 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTPVDSGAEEEKSGTAAVKKPSPSKARKKKLNKKGRKMVGRKRGRPKKMSAT
NPERKPKKTQSALDLLHAQTVSRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPT
PPALHRLLESFRIQYLQFLAYTKTPQYKATLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EESKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALALQLRGKPEADPGRLHLELDCARFSLPPFSSLSPELSMNGHAASYELCSAL
GRPSPKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKLVLRRHLS
QDHAASGKAAASELHPRAEHAKENGLPYQSPGITNGIKLSPQDPRPSSPTALQMGEKGPE
KGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPA
RESSSTLEKQVAANTHGAGGNTAGSKSLALAPTGFAYSGSVAISGALAGSPAPLGPGAEP
PALDESSSSGSLFATVGSRSSTPQHPPLLTQPRTCGSASPAPQLCASPRLGTLGPLPESG
KGDLPCDASFSDPESEAKRRIVFTISAGASSAKQSPSSKHSPLPSGARGDGGQGHGPDSR
KRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKI
ATISLESKSPPKTLENAGGSLAGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLQA
ASALSHNSLFAFRPGLEEPSAADGKLATHSRKSFPGTLPGAGGLSPNSLPASGFALGGGL
AADLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEGGAAESGPFANKRQLDGLGPKG
EGALPTCGPPDKASTAHSKAGKGREREPDVKNGHNLFMAAAAAPPAGLLSGPGLAPAASS
AGGTAPSVQTHRPFLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAAT
RLTNSHAMGSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSTTLSLTPLQAVA
STPASSFQAPSSAEPRPPQPPPHLGRPPPGQPALHAPPHPNATLPPPPALLPANSEPVLL
QNLASLPANQAFLPAASAASLPPANASLSIKLASLPHKVSRPALTVHHQPLPGLALAQAA
PVNPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5145 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggctgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atcagatgggtctgtgaggaaatcccggatctcaagcttgctatggagaattacgtttta
attgactacgataccaaaagctttgagagtatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggtaccacacagcccatgaagctgaacaca
cggccgtccactgggctcctgcggcacatcctgcagcaggtctacaaccactcggtgacc
gaccctgagaagctcaacaactatgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgacctgttcgtg
gacctgggcagtggggtgggccaggttgtgctgcaggttgccgcggccaccaactgcaaa
catcattatggtgtagagaaagctgacatcccagccaagtacgcggagacgatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagagg
ggggacttcctctcggaggagtggagagaacggattgctaacacaagtgttgtatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcaccgctaaaa
ggctcggtgtcatggacagggaagccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctaaaaaatcctaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcaacacaaccacgcccaccaaggtgccc
gagagcaaggcagctgtgccggcagacacccccgtggactccggtgctgaggaggagaaa
tccgggacagccgctgtcaagaagccatctccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggtgggtcggaagcgtgggcgccccaagaagatgagtgccacc
aaccccgagcgcaagcccaagaagacccagagcgccctggacctgctgcacgcccagacc
gtgtcacgagcggcctcccccttgccgcaggacgcgcacaggccacctcacagcccattc
taccagctacctcccagcgtgcagcggcctacccccgagcagctgctgctggcacccacc
ccgcccgcgctgcacaggctgctagagtccttcaggattcagtacctacagttcctggca
tacacgaagacccctcagtacaaggccaccctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctaggcgcagcgcagcagctgtttggccactgccaagctcagaag
gaggagagcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcagttgagggaa
cagacggagcagctagagaagggcaaccgggagctgaggagccagagcctgcggctgctc
aaggcacggtgtgaggagctgaagctggactggtccacgctgtccctggagaatctgctg
aaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctggaactg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctccagctcaag
tcctgcgtgccgcctgatgaggcactggccctgcagcttcgtgggaagccagaggccgat
cctggccggcttcacttggagctggactgcgcccgcttctccctgccgcctttcagcagc
ttgagccccgagctctccatgaatggccacgcggctagctatgagctctgcagcgcactg
ggtcggccctcacccaagcagaacaccccccagtacctggcctccccgctagaccaggag
gtcgtgccctgcacccctagccacagtggccggccacggctggagaagctgtccggcctg
gccctgcctgactacaccaggctatcccctgccaagctggtgctgcggcgccacctgagc
caggaccacgcggccagtggcaaggcagctgccagtgagctgcacccacgagccgagcat
gccaaggagaacgggctcccttaccagagccctggcattaccaacggcatcaagctgagc
ccacaagacccccgaccttcatcccccacggctttacagatgggagagaagggccccgag
aagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccactgagcactgtgcagcccagcaagctgcccgtcagcatccccctggccagc
gtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctgggccaccggcc
cgagagtcctcgtctacgctggagaagcaggtggctgctaacacccatggtgccggaggc
aacactgctgggagcaagagcctcgccctggctcccacaggctttgcatacagcggctcg
gtggccatcagtggggccctggcaggcagcccggcacccctcggccctggagctgagccc
ccggccctggacgagtcctccagctctggaagcctctttgccactgtggggtcccgcagc
tccaccccgcagcacccacccctgctgacgcagccacgcacctgcggctcagcctcgccg
gccccccagctctgcgccagcccccggctaggcaccctgggcccgctccccgagtctggc
aaaggagacctgccctgcgatgccagcttttcagaccctgagagcgaagccaaaaggagg
atcgtcttcaccatctcggcgggtgccagcagcgccaagcagtcaccttccagcaaacac
agccctctgccctcgggtgcccgtggggatggtggccagggccatgggccagacagccgc
aagcggggccggaggaagcgggcatcggcggggacccccagcctgagctcgagtgtgtcc
cccaagcgccgggccttgccatctgtcgctgggcttttcacgcagtcttcagggtccccc
ctgaatctcaactccatggtcagcaacatcaaccagcccctggagatcacggccatctcg
tcccctgagagctccctaaagagctcacccgtcccctaccaggacaatgaccagccacct
gtgctcaagaaggagaagcccctgagccagaccaacggcgcccactactccccactgacc
tcggacgaggagcccggctctgaggatgagcccggcagtgccagaattgagagaaaaatt
gcaacaatctccttagaaagcaagtctccaccaaaaaccttggaaaatgcaggtggcagc
ctagcaggaaggaaggcaccgctggccagcgagccggtcaacagcagcaagtggaagtcc
accttctcacccatctccgacctgggcctggccaaggcagccgacagcccgctgcaggct
gcctccgctctgagccacaactccctgttcgctttccggcccggcctggaggagcccagc
gcagccgatggcaagctggccacccactccaggaagagcttcccaggcaccctgccaggg
gcaggcgggctgagccccaatagccttcctgccagtggcttcgccctgggcgggggccta
gcagctgacctcagtttacacagcttcagtgatggtgcttctctttcccacaaggccccc
gaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaggagggtggc
gctgcagagtctggccccttcgcgaacaagcggcagctggatggactgggcccaaaaggc
gagggggcccttcccacatgcggacccccggacaaggcctccacagcgcatagcaaggca
ggcaagggccgcgagcgcgagcccgacgtcaagaacggccacaacctgttcatggccgct
gccgccgcgccccctgcaggcctcctcagcggcccaggtcttgccccagcggcatcctcg
gcaggtggcacagccccgtccgtgcagacccaccgccccttcctgggcgccttcgccccc
gggccacagttcgcgctgggccccatgtcgctacaggccaacctgggcccgtctgtgctg
cagtccctgttcagttctgtgcccgccgccggcctggttcacgtctcgactgccgccacc
agattgaccaactcgcacgccatgggcagcttctcttccggggtggccggcggcgcagtt
ggaggtgtctttaaccacgcggtgcctcccgcctccgcccatccgtttggagccagtttc
ggcagtggggctgcatgtcgcagcaccacgctgagcttaaccccgctgcaggcggtggcc
agcaccccagcctcttcctttcaggccccgtcctctgcggagccgaggccaccccaaccc
cctccgcacctgggccggccccctccggggcaacctgccctccatgcacccccccatcct
aacgccaccttgcctcctccccctgcgctgctcccagctaactctgagcccgtgcttctg
cagaacctcgcatccctccctgctaaccaagctttcttgcccgccgcctctgccgcctct
ctgccgcctgctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggtgtcc
cggcccgccttgacggtgcaccaccagcccctgcctgggttggccctggcccaggccgcg
cccgtgaacccacaggccagctccacggggccgcccgccgtgtgggtttcccttggcatg
ccgcctccgtatgccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
