Oryx dammah (scimitar-horned oryx): 120873247
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Entry
120873247 CDS
T07255
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
oda
Oryx dammah (scimitar-horned oryx)
Pathway
oda00562
Inositol phosphate metabolism
oda01100
Metabolic pathways
oda01521
EGFR tyrosine kinase inhibitor resistance
oda04012
ErbB signaling pathway
oda04014
Ras signaling pathway
oda04020
Calcium signaling pathway
oda04062
Chemokine signaling pathway
oda04064
NF-kappa B signaling pathway
oda04066
HIF-1 signaling pathway
oda04070
Phosphatidylinositol signaling system
oda04072
Phospholipase D signaling pathway
oda04360
Axon guidance
oda04370
VEGF signaling pathway
oda04380
Osteoclast differentiation
oda04611
Platelet activation
oda04613
Neutrophil extracellular trap formation
oda04625
C-type lectin receptor signaling pathway
oda04650
Natural killer cell mediated cytotoxicity
oda04662
B cell receptor signaling pathway
oda04664
Fc epsilon RI signaling pathway
oda04666
Fc gamma R-mediated phagocytosis
oda04670
Leukocyte transendothelial migration
oda04722
Neurotrophin signaling pathway
oda04750
Inflammatory mediator regulation of TRP channels
oda04919
Thyroid hormone signaling pathway
oda04933
AGE-RAGE signaling pathway in diabetic complications
oda04935
Growth hormone synthesis, secretion and action
oda05167
Kaposi sarcoma-associated herpesvirus infection
oda05169
Epstein-Barr virus infection
oda05170
Human immunodeficiency virus 1 infection
oda05171
Coronavirus disease - COVID-19
oda05200
Pathways in cancer
oda05205
Proteoglycans in cancer
oda05206
MicroRNAs in cancer
oda05214
Glioma
oda05223
Non-small cell lung cancer
oda05225
Hepatocellular carcinoma
Module
oda_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
oda00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
120873247 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
120873247 (PLCG2)
04014 Ras signaling pathway
120873247 (PLCG2)
04370 VEGF signaling pathway
120873247 (PLCG2)
04064 NF-kappa B signaling pathway
120873247 (PLCG2)
04066 HIF-1 signaling pathway
120873247 (PLCG2)
04020 Calcium signaling pathway
120873247 (PLCG2)
04070 Phosphatidylinositol signaling system
120873247 (PLCG2)
04072 Phospholipase D signaling pathway
120873247 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
120873247 (PLCG2)
04613 Neutrophil extracellular trap formation
120873247 (PLCG2)
04625 C-type lectin receptor signaling pathway
120873247 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
120873247 (PLCG2)
04662 B cell receptor signaling pathway
120873247 (PLCG2)
04664 Fc epsilon RI signaling pathway
120873247 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
120873247 (PLCG2)
04670 Leukocyte transendothelial migration
120873247 (PLCG2)
04062 Chemokine signaling pathway
120873247 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
120873247 (PLCG2)
04919 Thyroid hormone signaling pathway
120873247 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
120873247 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
120873247 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
120873247 (PLCG2)
04380 Osteoclast differentiation
120873247 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120873247 (PLCG2)
05206 MicroRNAs in cancer
120873247 (PLCG2)
05205 Proteoglycans in cancer
120873247 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
120873247 (PLCG2)
05214 Glioma
120873247 (PLCG2)
05223 Non-small cell lung cancer
120873247 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
120873247 (PLCG2)
05171 Coronavirus disease - COVID-19
120873247 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
120873247 (PLCG2)
05169 Epstein-Barr virus infection
120873247 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
120873247 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120873247 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oda04131
]
120873247 (PLCG2)
Enzymes [BR:
oda01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
120873247 (PLCG2)
Membrane trafficking [BR:
oda04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
120873247 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
120873247 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
120873247
NCBI-ProteinID:
XP_040110000
LinkDB
All DBs
Position
Unknown
AA seq
1262 aa
AA seq
DB search
MANVDTLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEG
FLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFILSTLSLAADSKEDATKWL
SGLKILHQEVMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVNSAKFL
KDKFLEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFLLGNTDRPDASAVHL
HDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWD
EKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDCWDG
PDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARVFKE
VFGDLLLTKPKEASADQLPSPSQLRGKIVIKHKKLGPRGDVDVNMEDKKDEHKQQGELHM
WDPIDQKWTRHYCAIADAKLSFSDDIEQTVEEELPLDIPPTELHFGEKWFHKKVEKRTSA
EKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYYLTD
NLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDMLMRV
PRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKH
ALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYRAK
QSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISPAEGEEADKQIIEDN
PLGSLCRGILNLNIYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDSVEELFEWFQSI
REITWKMDTKENNLKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKA
DSIVRQKPSDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQM
NHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSIACP
FVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPSLAFLRFVVYEEDMFS
DPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQL
RRRQEELNNQLFLYDTHQNLRSANRDALVREFNVNENQLQLYQEKCNRRLREKRVSNSKF
YS
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
atggccaacgtggacaccctcccagagtacgagaagagtcagatcaagcgggccctggag
ctgggcaccgtcatgactgtgttcagcttccgcaagtccaccccggaacggaggaccgtc
caggtgatcatggagacgcggcaggtggcctggagcaagacggctgacaagatcgagggc
ttcctggacatcatggagataaaggagatccggccagggaagaactccaaggatttcgag
cgcgcgaaagcggtccgccagaaggaagagtgctgcttcaccatcctgtacggcacccag
tttatcctcagcacgctcagcctggcagccgactcgaaggaagatgcaactaagtggctg
tctggcttgaagatcttacaccaggaagtgatgagcgcgtccacccccaccatcatcgag
agctggctgagaaagcagatttattctgtggatcaaaccaggagaaacagcatcagcctc
cgggagctgaagaccatcttgcccctggtcaacttcaaagtgaacagtgccaagttcctg
aaagacaagttcctggaaataggcgcacacaaagatgaactcagctttgaacagttccat
ctcttctataaaaaactcatgtttgaacagcagaaatcgatccttgacgaattcaaaaag
gattcttccgtgttcctcttgggcaacaccgaccggccggacgcctctgctgtccacttg
catgacttccagcggtttctcttgcatgaacagcaggagctttgggctcaggatctgaac
aaagtccgtgagcggatgacgaagtttattgacgacaccatgagggaaactgctgaaccc
ttcttgtttgtggatgagttcctcacgtacctgttttcccgggagaacagcatctgggac
gagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtctcattactggatc
tcctcgtctcacaacacgtacctcacgggggaccagctgcggagcgagtcgtccacggag
gcctacatccgctgcctgcggatgggctgccgctgcatcgagctggactgctgggacggg
cccgacggcaagcccatcatctaccacggctggacgcggaccaccaagatcaagttcgac
gacgttgtgcaggccatcaaagaccacgcctttgtcacctccagcttccccgtgatcctg
tccatcgaggagcactgctgtgtggagcagcagcgccacatggccagggtgttcaaggag
gtgtttggagacctgctgctgaccaaacccaaggaggccagtgccgaccagctgccgtcg
cccagccagctgcgcgggaagatcgtcatcaagcataagaagctgggcccccgtggtgac
gtggacgtcaacatggaggacaagaaggacgagcacaagcagcagggcgaactgcacatg
tgggaccccatcgaccagaaatggactcggcactactgtgccattgctgatgccaagctg
tccttcagcgatgacattgaacagactgtggaagaggagctgcccctggatatacccccc
acagagctgcattttggggagaagtggttccacaagaaagtggagaagaggacaagtgcc
gagaagctgctgcaggaatactgcgctgagacagggggcaaggatgggaccttcttggtg
cgggagagtgagactttccccaacgactacaccctgtccttctggcggtcaggccgcgtg
cagcactgccggatccgctccaccatggagggcgggaccatgaagtactacctgaccgac
aacctcatgttcaccagcatctacgccctcatccagcactaccgcgagacacacctgcgc
tgcgccgagttcgagctccggctgaccgaccccgtgcccaaccccaacccgcacgagtcc
aagccgtggtactacgatgggctgagccgcggagaagcggaggacatgctgatgagggtc
ccccgggacggggccttcctgatccggaagcgggaaggtactgactcctacgccatcacc
ttcagggccaggggcaaggtgaagcactgtcgcatcaaccgagacggccggcacttcgtg
ctgggcacctccgcctactttgagagcctcgtggagctggtcagctactatgagaagcat
gcactctaccggaagatgaaactgcgctatcctgtgacccccgagctgctggagcgctac
aacatggaaagagatataaactccctctatgatgtcagcaggatgtatgtggatcccagt
gaaatcaatccttcaatgcctcagagaaccgtgaaagctctgtatgactacagagccaag
cagagtgatgagctgagcttttgccgcggtgccctcatccacaacgtctccaaggagccc
gggggctggtggaaaggagactatgggaccagaatccagcagtacttcccgtccaattat
gtcgaggacatttcaccagcagaaggggaggaggcggataagcagattattgaagacaat
cccttagggtccctttgcagaggaatcctgaatctcaacatctataatgttgttaaagcc
ccacacgggaagaaccagaagcctttcgtctttatcttggagcccaagaagcagggcgac
cctccggtagagtttgccacggacagcgtggaggagctgttcgagtggttccagagcatc
cgggagatcacctggaagatggacaccaaggagaacaacttgaagtactgggagaagaac
cagtccatcgccatcgagctctcggacctggtcgtctactgcaagccaaccagcaagacc
aaggacaacctcgaaaaccctgacttccgagaaatccgctccttcgtggagacgaaggct
gacagtatcgtcagacagaaacccagcgatctcctgaaatacaatcaaaagggcctgacc
cgtgtgtaccccaaaggacagcgggtggactcgtccaactacgaccccttccgcctctgg
ctgtgcggctcccagatggtggcgctcaatttccagactccagataagtacatgcagatg
aaccacgcgctattctccctcaacgggcggacgggctacgtgctgcagcctgagagcatg
agggcggagaagtacgaccccatgccacccgagtcccagaggaagatcctcatgaccctg
acagtcaaggtactgggggcccgtcatctccccaaacccggacgaagcatcgcgtgtccc
tttgtggaggtggagatatgcggagcggagtatgacaacaacaagttcaagacgacagtt
gtgaatgacaatggcctcagccctgtttgggccccaacgcaggagaaggtgacgtttgag
atttatgaccccagccttgcgtttctgcgctttgtggtttatgaggaagatatgttcagc
gatcccaactttctggcccatgccacgtaccccattaaaggaatcaagtcaggatttaga
tctgtgcctctgaagaacggctacagtgaagacattgagctggcgtccctcctggttttc
tgtgagatgcggccagtcctggagagtgaagaggagctgtattcctcctgccgccagctg
cggaggcggcaagaagaactgaacaaccagctctttctgtacgacacccaccagaacctg
cgcagcgccaaccgcgatgccctggtcagagaattcaacgtcaacgagaaccagctgcag
ctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaacagcaagttt
tactcatag
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integrated database retrieval system
