KEGG   Oryx dammah (scimitar-horned oryx): 120880186
Entry
120880186         CDS       T07255                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
oda  Oryx dammah (scimitar-horned oryx)
Pathway
oda00562  Inositol phosphate metabolism
oda01100  Metabolic pathways
oda01521  EGFR tyrosine kinase inhibitor resistance
oda01522  Endocrine resistance
oda01524  Platinum drug resistance
oda04012  ErbB signaling pathway
oda04014  Ras signaling pathway
oda04015  Rap1 signaling pathway
oda04024  cAMP signaling pathway
oda04062  Chemokine signaling pathway
oda04066  HIF-1 signaling pathway
oda04068  FoxO signaling pathway
oda04070  Phosphatidylinositol signaling system
oda04071  Sphingolipid signaling pathway
oda04072  Phospholipase D signaling pathway
oda04081  Hormone signaling
oda04140  Autophagy - animal
oda04145  Phagocytosis
oda04150  mTOR signaling pathway
oda04151  PI3K-Akt signaling pathway
oda04152  AMPK signaling pathway
oda04210  Apoptosis
oda04211  Longevity regulating pathway
oda04213  Longevity regulating pathway - multiple species
oda04218  Cellular senescence
oda04360  Axon guidance
oda04370  VEGF signaling pathway
oda04380  Osteoclast differentiation
oda04510  Focal adhesion
oda04517  IgSF CAM signaling
oda04518  Integrin signaling
oda04550  Signaling pathways regulating pluripotency of stem cells
oda04611  Platelet activation
oda04613  Neutrophil extracellular trap formation
oda04620  Toll-like receptor signaling pathway
oda04625  C-type lectin receptor signaling pathway
oda04630  JAK-STAT signaling pathway
oda04650  Natural killer cell mediated cytotoxicity
oda04660  T cell receptor signaling pathway
oda04662  B cell receptor signaling pathway
oda04664  Fc epsilon RI signaling pathway
oda04666  Fc gamma R-mediated phagosome formation
oda04668  TNF signaling pathway
oda04670  Leukocyte transendothelial migration
oda04722  Neurotrophin signaling pathway
oda04725  Cholinergic synapse
oda04750  Inflammatory mediator regulation of TRP channels
oda04810  Regulation of actin cytoskeleton
oda04910  Insulin signaling pathway
oda04914  Progesterone-mediated oocyte maturation
oda04915  Estrogen signaling pathway
oda04917  Prolactin signaling pathway
oda04919  Thyroid hormone signaling pathway
oda04923  Regulation of lipolysis in adipocytes
oda04926  Relaxin signaling pathway
oda04929  GnRH secretion
oda04930  Type II diabetes mellitus
oda04931  Insulin resistance
oda04932  Non-alcoholic fatty liver disease
oda04933  AGE-RAGE signaling pathway in diabetic complications
oda04935  Growth hormone synthesis, secretion and action
oda04960  Aldosterone-regulated sodium reabsorption
oda04973  Carbohydrate digestion and absorption
oda05010  Alzheimer disease
oda05017  Spinocerebellar ataxia
oda05020  Prion disease
oda05100  Bacterial invasion of epithelial cells
oda05132  Salmonella infection
oda05135  Yersinia infection
oda05142  Chagas disease
oda05146  Amoebiasis
oda05160  Hepatitis C
oda05161  Hepatitis B
oda05162  Measles
oda05163  Human cytomegalovirus infection
oda05164  Influenza A
oda05165  Human papillomavirus infection
oda05166  Human T-cell leukemia virus 1 infection
oda05167  Kaposi sarcoma-associated herpesvirus infection
oda05168  Herpes simplex virus 1 infection
oda05169  Epstein-Barr virus infection
oda05170  Human immunodeficiency virus 1 infection
oda05171  Coronavirus disease
oda05200  Pathways in cancer
oda05203  Viral carcinogenesis
oda05205  Proteoglycans in cancer
oda05206  MicroRNAs in cancer
oda05207  Chemical carcinogenesis - receptor activation
oda05208  Chemical carcinogenesis - reactive oxygen species
oda05210  Colorectal cancer
oda05211  Renal cell carcinoma
oda05212  Pancreatic cancer
oda05213  Endometrial cancer
oda05214  Glioma
oda05215  Prostate cancer
oda05218  Melanoma
oda05220  Chronic myeloid leukemia
oda05221  Acute myeloid leukemia
oda05222  Small cell lung cancer
oda05223  Non-small cell lung cancer
oda05224  Breast cancer
oda05225  Hepatocellular carcinoma
oda05226  Gastric cancer
oda05230  Central carbon metabolism in cancer
oda05231  Choline metabolism in cancer
oda05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oda05415  Diabetic cardiomyopathy
oda05417  Lipid and atherosclerosis
oda05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oda00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120880186 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    120880186 (PIK3CD)
   04014 Ras signaling pathway
    120880186 (PIK3CD)
   04015 Rap1 signaling pathway
    120880186 (PIK3CD)
   04370 VEGF signaling pathway
    120880186 (PIK3CD)
   04630 JAK-STAT signaling pathway
    120880186 (PIK3CD)
   04668 TNF signaling pathway
    120880186 (PIK3CD)
   04066 HIF-1 signaling pathway
    120880186 (PIK3CD)
   04068 FoxO signaling pathway
    120880186 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    120880186 (PIK3CD)
   04072 Phospholipase D signaling pathway
    120880186 (PIK3CD)
   04071 Sphingolipid signaling pathway
    120880186 (PIK3CD)
   04024 cAMP signaling pathway
    120880186 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    120880186 (PIK3CD)
   04152 AMPK signaling pathway
    120880186 (PIK3CD)
   04150 mTOR signaling pathway
    120880186 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    120880186 (PIK3CD)
   04517 IgSF CAM signaling
    120880186 (PIK3CD)
   04518 Integrin signaling
    120880186 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    120880186 (PIK3CD)
   04140 Autophagy - animal
    120880186 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    120880186 (PIK3CD)
   04218 Cellular senescence
    120880186 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120880186 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    120880186 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    120880186 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    120880186 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    120880186 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    120880186 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    120880186 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    120880186 (PIK3CD)
   04660 T cell receptor signaling pathway
    120880186 (PIK3CD)
   04662 B cell receptor signaling pathway
    120880186 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    120880186 (PIK3CD)
   04666 Fc gamma R-mediated phagosome formation
    120880186 (PIK3CD)
   04670 Leukocyte transendothelial migration
    120880186 (PIK3CD)
   04062 Chemokine signaling pathway
    120880186 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    120880186 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    120880186 (PIK3CD)
   04929 GnRH secretion
    120880186 (PIK3CD)
   04915 Estrogen signaling pathway
    120880186 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    120880186 (PIK3CD)
   04917 Prolactin signaling pathway
    120880186 (PIK3CD)
   04926 Relaxin signaling pathway
    120880186 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    120880186 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    120880186 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    120880186 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    120880186 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    120880186 (PIK3CD)
   04722 Neurotrophin signaling pathway
    120880186 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120880186 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    120880186 (PIK3CD)
   04380 Osteoclast differentiation
    120880186 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    120880186 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    120880186 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120880186 (PIK3CD)
   05206 MicroRNAs in cancer
    120880186 (PIK3CD)
   05205 Proteoglycans in cancer
    120880186 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    120880186 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    120880186 (PIK3CD)
   05203 Viral carcinogenesis
    120880186 (PIK3CD)
   05230 Central carbon metabolism in cancer
    120880186 (PIK3CD)
   05231 Choline metabolism in cancer
    120880186 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120880186 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    120880186 (PIK3CD)
   05212 Pancreatic cancer
    120880186 (PIK3CD)
   05225 Hepatocellular carcinoma
    120880186 (PIK3CD)
   05226 Gastric cancer
    120880186 (PIK3CD)
   05214 Glioma
    120880186 (PIK3CD)
   05221 Acute myeloid leukemia
    120880186 (PIK3CD)
   05220 Chronic myeloid leukemia
    120880186 (PIK3CD)
   05218 Melanoma
    120880186 (PIK3CD)
   05211 Renal cell carcinoma
    120880186 (PIK3CD)
   05215 Prostate cancer
    120880186 (PIK3CD)
   05213 Endometrial cancer
    120880186 (PIK3CD)
   05224 Breast cancer
    120880186 (PIK3CD)
   05222 Small cell lung cancer
    120880186 (PIK3CD)
   05223 Non-small cell lung cancer
    120880186 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120880186 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    120880186 (PIK3CD)
   05161 Hepatitis B
    120880186 (PIK3CD)
   05160 Hepatitis C
    120880186 (PIK3CD)
   05171 Coronavirus disease
    120880186 (PIK3CD)
   05164 Influenza A
    120880186 (PIK3CD)
   05162 Measles
    120880186 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    120880186 (PIK3CD)
   05163 Human cytomegalovirus infection
    120880186 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120880186 (PIK3CD)
   05169 Epstein-Barr virus infection
    120880186 (PIK3CD)
   05165 Human papillomavirus infection
    120880186 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120880186 (PIK3CD)
   05135 Yersinia infection
    120880186 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    120880186 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    120880186 (PIK3CD)
   05142 Chagas disease
    120880186 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120880186 (PIK3CD)
   05017 Spinocerebellar ataxia
    120880186 (PIK3CD)
   05020 Prion disease
    120880186 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120880186 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    120880186 (PIK3CD)
   05415 Diabetic cardiomyopathy
    120880186 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    120880186 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    120880186 (PIK3CD)
   04931 Insulin resistance
    120880186 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120880186 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    120880186 (PIK3CD)
   01524 Platinum drug resistance
    120880186 (PIK3CD)
   01522 Endocrine resistance
    120880186 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oda04131]
    120880186 (PIK3CD)
Enzymes [BR:oda01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     120880186 (PIK3CD)
Membrane trafficking [BR:oda04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    120880186 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2
Other DBs
NCBI-GeneID: 120880186
NCBI-ProteinID: XP_040119302
LinkDB
Position
Unknown
AA seq 1044 aa
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTMRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNLAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELMHLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaatgtg
gcagttgatttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgcgcccagtatgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgcctgtcctgcgg
ctggtggcccgcgaaggtgaccgtgtgaagaagctcatcaactcgcagatcagcctgctc
atcggcaaaggcctccacgagtttgactccttgcaagacccggaggtgaatgacttccga
ggcaagatgcgccagttctgcgaggaggcagctgcccgcaggcagcagctgggctgggag
gcctggctgcagtacagcttccctctgcagttggagccctcggcgcggagctgggggccg
ggcacaatgcgcgtccccagtcgggcactcctggtcaatgtcaagtttgagggcagcgag
gagagcttcaccttccaggtatccaccaaggatgtgcccctggcactgatggcctgcgcc
ctccgaaagaaggccacggtgttccggcagccgctggtggagcagcctgaggactacaca
ctgcaggtgaacggcaagcatgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagtgggctgaccccccacctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgagcagagcaaccttgccccccaagtccagaagccacgc
accaaaccaccccccatccccatgaagaagccctcctccgtgtccctctggtccctggag
cagcctttctacatcgagctgatccagggcagcaaagtgaatgccgacgagcggatgaag
ctggtggtgcaggccgggctcttccacggcaatgagacactatgcaagacggtgtccagc
tcagaggtgagcgtgtgttcggagcccgtgtggaagcagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccggctctgcttcgcgctttacgcggtgatcgagaag
gccaagaaggcccgctccaccaagaagaagtccaagaaggcggactgtcccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagacgggcgagcgctgtctctac
atgtggccctctgtcccagacgagaaaggggagctattgaacccctgtgggaccgtgcgg
agtaaccccaacactgagagtgcagccgccctggtcatctttctccccgaggtggcccct
caccctgtatactacccttccctggacaagatcctggagctggggcggcttggagagcac
ggacgcttcacggaggaggagcagctgcagctgcgggagatcctggagcggcggggttcc
ggggaactgtacgagcacgagaaggacctggtgtggaagatgcggcacgagatccaggag
cactttcccgaggctctagcccggctgctgctggtcactaagtggaacaaacacgaggac
gtggcccagatgctctacctgctctgctcctggcctgaattgcccgttctgagcgccctg
gagttgctagacttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctg
cggaaactaacggacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tatgagtcctacctcgactgcgagctgaccaaattcctgctggaccgggccctggccaat
cgcaggatcggccacttcctcttctggcacctccgctccgagatgcacgtgccgtcggtg
gctctgcgctttggcctcatcatggaagcctattgccggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctcaatgacttcgtcaaa
gtgagctcccagaagacccccaaaccccaggccaaggagctgatgcacctgtgcctgcgc
caggagacctacctggaggccctctcccacttgcagtccccacttgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaaacccctgtgg
gtcatgtacagcaacgaggaggcaggcagcgatggcaccgtgggcatcatctttaagaat
ggggacgacctccgccaggacatgctgaccctgcagatgatccagctcatggacattctg
tggaagcaggagggcttggacctgaggatgaccccctatggctgcctctccactggggac
cgcacaggccttattgaggtggtgcttcactcggacaccattgccaacatccagctgaac
aagagcaacatggcagccacggccgccttcaataaggatgctctgctcaactggctcaag
tccaagaaccctggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctactgtgtggccacctatgtgctgggcatcggcgatcgccacagcgacaacatcatg
atccgagagaacgggcagctgttccacattgatttcggccactttctggggaatttcaag
accaagtttggaatcaaccgtgagcgggtcccgttcatcctcacctatgacttcgtccac
gtgatccagcaggggaagacgaataatagtgagaagtttgaaaggttccggggctattgt
gagacggcctacaccatcctgcggcgccatgggctccttttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggat
tctctggcattggggaaaacggaggaggaggctctgaagcacttccgagtgaagtttaat
gaagccctccgggaaagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gataacaggcaataa

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