Osmerus eperlanus (European smelt): 134021197
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Entry
134021197 CDS
T10927
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
oep Osmerus eperlanus (European smelt)
Brite
KEGG Orthology (KO) [BR:
oep00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oep01001
]
134021197 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oep04131
]
134021197 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oep04147
]
134021197 (lrrk2)
Enzymes [BR:
oep01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
134021197 (lrrk2)
Protein kinases [BR:
oep01001
]
Serine/threonine kinases: TKL group
LRRK family
134021197 (lrrk2)
Membrane trafficking [BR:
oep04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
134021197 (lrrk2)
Exosome [BR:
oep04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
134021197 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_14
LRR_1
LRR_6
LRR_NXF1-5
Beta-prop_EML_2
Arf
AAA_16
AAA_22
Beta-prop_BBS7
LRR_R13L1-DRL21
NACHT
LRR_13
G-alpha
WDR55
nSTAND3
Gtr1_RagA
GTP_EFTU
Viral_helicase1
DLIC
cobW
Septin
TFCD_C
AAA_7
LRR_5
MMR_HSR1
T2SSE
ABC_tran
SRPRB
Ank_2
ATP_bind_1
TniB
AAA_19
AAA_30
Kdo
TsaE
PduV-EutP
Motif
Other DBs
NCBI-GeneID:
134021197
NCBI-ProteinID:
XP_062317748
LinkDB
All DBs
Position
5:13660203..13686378
Genome browser
AA seq
2531 aa
AA seq
DB search
MKDKEELEETLKKLLVRLKNLEEGKQLSTLVQIIEDLIFLAHTDGCAAELFEDKAVQGPL
MVVLSFYSNSKRVQQAGWSLLCRLIEICPSTLDQLTKPLEAGKDWEVLGVHQQILKVLSQ
HSRDCRTMMVGLRTLALLLQSDIIKLLVLDAEEDVFDLIVGAMKEFSSSEEVQLQGFRAL
QLLLEQVSDDHLVEFVENKDHSVVLAALLSSQASEDLLLQAMKVLLPLAGPASNVEILMS
GGARCYSVVAGAMDSHPALEPLQEVGCQLIRKFTAVCYYNILVLNGVHRVLVRASVTYPE
NTTLQAAALSCLAELTGTIMESKVVVQQGLDEGEEEQVGGQVEVDGMDLCWMKACCTALE
LHAADSTVQEAACWAIHNLLLHGSGLDYSIVDQENRAPVHRQVMAAMLLHSSSVRVFQAA
ACALGTLITFNPKMQSLLLSNGLHVNVVEMMKRHLNSPEVSASGCQLLHLLFRGRTANLD
EMNMAMNQILAAMKVHNFQPEVQVEALRASLVFLCPDRRLREHGVSVEDPDTVDVSLRVL
KNQCVVEGAHTIYLEALNRFIGCSAVQENGLRVLSALADCSGAVDLLCQQGAIDTVLHTL
QMFPQEQEIHYWGLNLLCYLVSKKKLSRMIVPVLASVLVTSLIEYKDYPEMLLKGFQVAL
RMLDACSGAAGDLQKEDFDRQVFQQLRDGPSDLYSNPLRKAACLALSKMASEADLRYGML
EKACEDGDEVMAECLIQLGADVNRKPKTESLIYQVCEKGGTLALVELLLSRGIHEQHLRS
ALAASTRRGDGPAIILLLGCLGLDRHNGALCLGGFRLGRLDAAWLGPLLVDRGRARSLRD
HNSKGARLGQYVCSFQRIKSTPCPLRSLADPCLTSGYMSDESDDSSFVSLEDSLVFYDDM
ESDGSDSLSLALKSPNDSSEEWRAGSFKKKQSRRRHASAEAGLSEVEPGEPHRRYGRTGS
NHKRVYSPVLGSGDNSASPIGERERIRLLDLSGNELESVSCLMDRGFVQQQLEHLTRLDL
SQNSLSEFPSTLCESLMSLTRLDLQGNQLQSLPVELLALPSLSTLNVSRNSVGPLLTLDP
ALTCPSLRQLNLSFNQITTFPQQLGRAMVRLEELFLEGNRMSELSTPLCLPEMKIIDVSK
NSVESISSNFLSGCPKLESFNASNNKLNSLSLLPSKIATLKLSNNSFSYIPNDVLNLPNL
RSVDMRTNNIQVLPGPGAWASVNLRELIFSQNRIEALDLSGPVHKWARLEKLHLSHNKLT
EIPPQMGQLEELTSLDVSHNGGLRSFPDEMGQLGRLWDLPLEGLRLHLDLKHIGNKTKDI
VRFLQQRLKKAVPYHRMKLIVVGNAGSGKTTLIRQLMKLKRSQQTSQRTTAGIDVCDWTI
RDRDRRNMVLNVWDFTGGEEFSGSHPHFLTPRALYLVVYDVSKGAAQVESLKPWLFNIKA
VAPLSPVILVGTHVDESVEAQLQACLERIREELLQRHGFHVVRDHHMVSVLEDLDAVAKL
RKAIAREVTGFKMQGQPVMGQLVPESYVELERRVLQERARAPAEFPVLQHQALLRLIQDS
PLEEAELPHAIHFLSEAGVLLHFDDPALQLRELYFIDPQWLCDIISQKLTVKSSGSWEHP
KGVVQRSLVEKLLSESKCFPMNYLTQYLKLLEKFQIALPFGVDQLLVPSSLPKSRPVIEL
PHCENSEVIVRLYEMPYFPMGYWSRQINRLLEVSSYLLRGRERALKPNRIYWRRGIYLSW
SPEAYCLVEASSLEGSSASFVKITVPCSRKGHVLLGQVTDHMDSLLEEWFPGLLATDMHG
SGETLLKKWALYSYEDGQDWSKMLLEDLFNHMENDCLLVNPDDPHCVLPISQIAPDLILS
DQPAETMLHNEELDFSKENPLGDGGFGTVYRGVYKNEEVAVKVFNKHASKIYIHRLLRQE
LAVLGRLHHPSLVALLAAGSAPQALVMELAPRGSLDSLFEHENGSLNRKLQHRIALQVAD
GLRYLHSSMIIYRDLKPHNILLFNLKTDSEIIAKITDYGIAQYCCSMGVRTSEGTPGFRA
PEVARGNVIYNQQADIFSFGLLIYDLLTCGERILDGMKFPSEFDEMAVRGKLPDPVTHYG
CCPWPGFQTLMNDCMKESPQNRPTSAQVFDRLNSGEMLCLMRELVVSQAPNAECFTVGAP
SGGDQVKVWVAGGSSTQRIGCISEVDLDTHTVTDQLQIDTSPVLCLVALQVPGKACDWLV
AGTQAGTLVVINTQDISSCHHLQSVTDAVTSLFFHSHPQLNKNYLLVGTADGVLTVYEES
ALQQENGRPVKSVNIGNVNTPLVCLGQSAHSLDRSTVWAGCGTRVLSLSVDYDIWRTINT
KPNFTHHLQRTASSEACVSRVVVEKHVYLSKAGGQTVEVWDKKSERMVDCIDCFQLIRHG
SSRRPTQGYPEMPPWACVKALMVQPGASLWIATRGGYLLLLELSNHQALQVMSPHCQSVR
GMACALIETLNRDDVVLVLGRRFSQGRSQSGGDESVLMFWNSALPREVKDLKKHCEKREE
IAAKMREQLHD
NT seq
7596 nt
NT seq
+upstream
nt +downstream
nt
atgaaggacaaggaagaactggaggagactctaaagaaactgttagtgagattgaaaaat
cttgaagaaggaaagcagttaagtacgctggttcaaatcatcgaagaccttattttcctg
gcccatacagatggatgtgcagctgaactgttcgaagacaaagcggttcaggggcctctt
atggttgtactgtcattttacagtaacagtaaaagagtgcagcaggcaggatggtccttg
ctgtgtcggctaatagaaatatgtcctagcaccttagaccagttgaccaagcctctggaa
gcagggaaagactgggaggtattgggtgtgcaccagcagatcctgaaggtgctttcccaa
cacagcagagactgccggacgatgatggtggggctcagaacactggctctcctcctccaa
tcagacatcatcaagctgttggttctagatgctgaggaggatgtatttgacctgattgtg
ggtgctatgaaggagttttcctccagcgaagaagttcaacttcaaggtttccgtgctctg
cagctgttgttggaacaagtgagcgatgaccacctggtggagtttgtggagaacaaggac
cacagtgtggttctagcagcactcctgagttcccaggccagtgaagacctgcttctacag
gccatgaaggttctgctccctctggcaggacccgccagcaacgtggagatcctcatgtcc
gggggagcacgttgttacagtgttgtggcgggagccatggactctcacccagcactggag
cctctgcaggaagttggttgccaattaatcaggaagttcaccgcagtgtgttactacaat
atcctggtgctgaacggtgtgcatagagtcctggtgagggctagtgtgacctacccagag
aacactaccctgcaggccgctgccctctcctgtctggccgaactcaccgggacgatcatg
gagagtaaggtggtggtccagcagggtctggatgagggagaggaggagcaggttggaggg
caggtggaggtggacggcatggacctgtgctggatgaaggcttgctgcacagccctggag
ctccacgcagcagattccaccgtccaggaagctgcatgttgggccattcacaacctgtta
ctacatgggagtggactagattattccatagtggaccaggaaaatagggcgcctgtccac
agacaggtaatggctgccatgctgctccactcctcctctgtcagggtgttccaggctgcc
gcctgtgccttgggcacgctcatcacatttaaccctaaaatgcagtctctgctgttgtcc
aatggcctccatgtcaacgtggtggagatgatgaagagacacttgaattctccagaagtt
tccgccagcggctgtcagctgctgcatctgctgttcaggggaaggactgccaatctggat
gagatgaacatggccatgaatcagatcctggcggccatgaaggtccataacttccagcct
gaggtccaggtggaggccttgagagccagcctggtcttcctctgcccagaccggcgcctg
cgggagcatggtgtctcggtggaagatccagacactgtggatgtctctctgagggtgctg
aagaaccagtgtgtggtggaaggggctcacaccatctacctggaggccctcaacaggttc
atcggctgctcagctgtccaggagaatggtctgagggttttgtctgcccttgctgattgc
tccggtgcagtggacctgctctgccagcagggggccatagacacggtgctgcacacacta
cagatgtttccccaggaacaagaaatacactactggggtttgaatctactctgctacctg
gtgtctaagaagaagctatcaagaatgatcgtccctgtcctggcctcggtccttgtcacc
tccctcatagagtacaaggactaccccgagatgctgttgaagggtttccaggtggctctg
cgcatgctggacgcctgttcaggggcggcgggggacctgcagaaggaggactttgatcgg
caggtcttccagcagctcagagacggcccttctgacctgtacagcaacccgctgcgcaag
gcggcgtgcctggccctgtccaagatggcgtccgaggccgacctgaggtacggcatgctg
gagaaggcatgcgaggacggggatgaggtcatggctgagtgtctcatccagctgggcgcg
gacgtcaacaggaagcccaagaccgaatccctcatataccaggtgtgcgagaagggcggg
accctggccctggttgagctgctgctgagccgtggcatccacgagcagcaccttcggagc
gcgctggctgccagcacgcggagaggagacgggcccgccatcatcctcctgctgggctgc
ctggggctggaccgccacaacggagccctctgtctgggcggcttcaggctcggacggctg
gacgccgcctggctcggccccctgctggtggaccgggggagagcacggagcctgcgcgac
cacaacagtaaaggtgcacgtctgggccagtacgtgtgctccttccaaagaatcaaaagc
accccatgtcctcttaggtcactagctgacccctgtctgacctctggctacatgtcggac
gagagcgatgactccagcttcgtctccctggaagacagcttggtgttctacgatgacatg
gaaagcgatggaagtgattccctgtctttagcccttaagtcacccaacgactcatcagaa
gagtggagagcaggatctttcaagaagaaacagagccgtcgcagacatgctagtgcagag
gctggcctgtctgaggttgagcctggggagcctcacaggagatatggcaggactggctcc
aaccataaaagagtctactccccagtgttggggtcaggggataattctgcctccccgatt
ggggaaagagagaggatccggctgctggacctatcagggaatgagctggagtctgtgtcc
tgcctgatggacaggggttttgtccaacagcagctggagcacctgactcgcctggacctg
agccagaacagcctgtcagagttcccatccacgctgtgtgagagcttgatgagtttgacc
cgtctggatctccaaggtaaccagctccagtccttgccagtcgaacttctcgccttgccc
tcgctgagcacgctcaatgtgtctcgcaactctgtgggtcctcttctgacccttgacccc
gcactgacctgcccatcgctacggcagctcaacttgtccttcaaccaaatcaccaccttc
cctcaacagctgggcagagccatggtgcgactggaagagctgtttctggaagggaacaga
atgagtgagctaagtactcctctgtgtctgcctgagatgaaaattattgacgtgagcaag
aacagcgtggagagcatctcctccaacttcctgtctggctgccccaagctcgagagcttc
aacgcctccaataacaaactcaattccttgtcactcctcccctcaaaaatagcaacgctg
aaactatccaataacagtttcagctacattccaaatgatgtgctcaatcttccaaatttg
cgttcggtggacatgaggaccaacaacatccaggttctacccggcccgggtgcgtgggct
tcggtaaacctgcgtgaactgattttcagtcagaaccgtattgaagctttggacctcagt
gggcccgtgcacaagtgggccagactggagaaactccacctgagtcacaacaagcttacc
gagatcccccctcagatgggccagctggaggagctgacctcactggacgtgagccacaac
gggggcctgcgctccttccctgacgagatgggccagctgggccggctgtgggacctcccc
ctggagggcctgcgcctccatctggacctcaaacacatcggcaacaagaccaaggacatc
gtcaggttcctgcagcagcgcctgaagaaggccgtgccgtaccaccgcatgaaactcatc
gtcgtggggaatgccgggagcggcaagaccaccctcatccggcagctcatgaagctcaag
cgctcccagcagacgtcgcagcggaccacggcaggcatcgacgtctgcgactggaccatc
cgggaccgcgacagaaggaacatggtcctcaatgtgtgggacttcaccggtggggaggag
tttagcggctcccacccccacttcctgacccccagggcgctctacctggtggtgtacgat
gtcagcaagggcgccgcccaggtggaatcgctcaaaccctggctgttcaacatcaaagcg
gtggccccgctgtcgcccgtcatcctggtgggcacccacgtggacgagagcgtggaggcc
cagctgcaggcctgcctggagcggatccgagaggagctgctgcagcgccacggcttccac
gtggtcagggaccaccacatggtgtctgtgctggaggacctcgacgccgtggcgaagctg
cgcaaggccatcgctcgggaggtgaccggcttcaagatgcagggccagccggtgatgggg
cagctggtcccagaaagctacgtggagctggagcggagagtgttgcaggagagggcccgg
gcccccgcggagttccccgtcctccagcaccaggccctgctgcggctcatccaggacagc
cccctggaggaggcggagctgccacacgccatccacttcctcagcgaggccggtgtcctc
ctgcactttgacgatcctgccctccagcttagagagctgtacttcatcgacccgcagtgg
ctttgcgacatcatctcgcagaaactgaccgtgaagagctcagggtcctgggagcacccc
aagggagttgtccagcgctcgctggtggagaagctcttgtctgagagcaagtgtttcccc
atgaactatctgacccagtacctcaaactcctggagaagttccagatcgccctgcccttt
ggggtcgaccagcttctagtacccagcagccttcccaagtccaggccggtgatagagctg
ccccactgtgagaactcggaggtgattgtgcgcctgtatgagatgccctactttcccatg
ggctactggtcacgccagatcaaccgtctactggaggtctcctcttacttgctgcgtggc
agagagagggctcttaagcccaacaggatctactggaggagaggcatctacctgagctgg
tctccagaggcctactgcctggtggaggccagctctctggagggaagctccgccagcttc
gtcaagatcacagtgccctgctcacgcaaaggtcacgtgctgctgggccaggtgacggac
cacatggactccctgctcgaggagtggttccctggcctgctggccacggacatgcacggc
agcggggagaccctgctgaagaagtgggccctgtacagctacgaggacggccaggactgg
agcaagatgctgctggaggatctgttcaaccacatggagaacgactgtctgctggtgaac
ccagacgaccctcactgcgtcctgcccatctctcagatcgccccagacctcatcctgagc
gaccagccggcagaaaccatgctccacaacgaggagcttgacttctccaaggagaaccca
ctgggggatggcggttttgggactgtctaccggggagtctacaaaaacgaagaagttgcg
gtgaaggttttcaacaagcatgcgtctaagatctacatccaccgcttgctacgacaggag
ttggcagtgctcggccgcctccaccaccccagcctggtggcccttctggcagccggctcg
gccccccaagccctggtgatggagctggcccctcgcggctccctggactccctgttcgag
catgagaacggcagtctcaaccgcaagttacagcaccgcatcgccctgcaagtggctgac
ggactccgatacctgcattcctctatgatcatctaccgcgacctgaagccccacaacatc
cttctcttcaacctcaagacggactctgagatcatcgccaagatcacagactacggcatc
gcccagtactgctgcagcatgggggtgcgcacctccgaaggaaccccaggtttcagggct
ccagaggtcgcccggggcaatgtgatctacaatcagcaggcggacatcttctccttcggc
ctgcttatttacgacctgctgacgtgcggcgaacgcattttggacggcatgaagttcccc
agcgagtttgacgagatggccgtgcgggggaagttaccagaccctgtgacgcactatggc
tgctgtccgtggcccggcttccagaccctgatgaatgactgcatgaaagagagtccccaa
aacagacctacctctgcacaggtgtttgacaggctgaactcgggggagatgctgtgtttg
atgagggagctggtggtgagccaggcgcccaatgcggagtgtttcaccgtgggggcgccc
agcggtggagaccaggtcaaggtctgggtggctggtggcagcagcacccagagaataggc
tgcatctccgaggtggacctggacacccacactgtcactgaccagcttcagatcgacacc
agtcccgtcctatgcctggtggcgctccaagtccccggcaaggcctgcgattggctggtg
gcgggcacccaggctggaaccctggtggtcatcaacacccaggacatatcatcatgccac
cacctacagagtgtcacagatgctgtgacctcgctgtttttccactctcatcctcagcta
aacaaaaattacttgctagtcgggaccgcagatggagttctgacggtttatgaagagtct
gctctccagcaggagaacgggaggccggtcaaaagcgtcaacatcgggaatgtcaacacc
cccctcgtgtgtctgggtcagtcggcccactccctggacaggagcacggtgtgggcaggc
tgtgggaccagagtcctgtccctctctgtagactacgacatctggaggaccatcaacaca
aagcccaacttcacccaccatttgcagaggacagcgagcagcgaggcgtgtgtgtcacgt
gtggtggtggagaagcacgtgtacttgagcaaagccgggggccagaccgtcgaggtttgg
gacaagaagagtgagaggatggtggactgcattgactgtttccagctaatcagacacggc
tccagtcggaggcccacgcagggctaccctgagatgcctccctgggcttgtgtcaaggct
ctcatggtgcagcccggggccagcctgtggatcgccaccaggggggggtacctgctcctg
ttggaactgtctaaccaccaggcgctgcaagtcatgagcccccactgccagtctgtccgc
ggcatggcctgcgcactcatagagacactgaaccgtgatgatgtggtcctggttttgggg
cgaaggttttcccagggtaggagtcagagtggaggagacgagtcggtgctgatgttctgg
aacagtgcccttccacgggaggtgaaggatctgaagaaacactgtgagaagagggaggag
atcgcagccaagatgagagagcagctccacgactga
DBGET
integrated database retrieval system
